Results for 'fMRI'

25 found
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  1. Productive Theory-Ladenness in fMRI.Emrah Aktunc - forthcoming - Synthese.
    Several developments for diverse scientific goals, mostly in physics and physiology, had to take place, which eventually gave us fMRI as one of the central research paradigms of contemporary cognitive neuroscience. This technique stands on solid foundations established by the physics of magnetic resonance and the physiology of hemodynamics and is complimented by computational and statistical techniques. I argue, and support using concrete examples, that these foundations give rise to a productive theory-ladenness in fMRI, which enables researchers to (...)
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  2.  70
    Using fMRI in Experimental Philosophy: Exploring the Prospects.Rodrigo Díaz - 2019 - In Eugen Fischer & Mark Curtis (eds.), Methodological Advances in Experimental Philosophy. London: Bloomsbury.
    This chapter analyses the prospects of using neuroimaging methods, in particular functional magnetic resonance imaging (fMRI), for philosophical purposes. To do so, it will use two case studies from the field of emotion research: Greene et al. (2001) used fMRI to uncover the mental processes underlying moral intuitions, while Lindquist et al. (2012) used fMRI to inform the debate around the nature of a specific mental process, namely, emotion. These studies illustrate two main approaches in cognitive neuroscience: (...)
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  3.  44
    Building a Science of Individual Differences From fMRI.Julien Dubois & Ralph Adolphs - 2016 - Trends in Cognitive Sciences 20 (6):425-443.
    To date, fMRI research has been concerned primarily with evincing generic principles of brain function through averaging data from multiple subjects. Given rapid developments in both hardware and analysis tools, the field is now poised to study fMRI-derived measures in individual subjects, and to relate these to psy- chological traits or genetic variations. We discuss issues of validity, reliability and statistical assessment that arise when the focus shifts to individual subjects and that are applicable also to other imaging (...)
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  4. Evaluating Methods of Correcting for Multiple Comparisons Implemented in SPM12 in Social Neuroscience fMRI Studies: An Example From Moral Psychology.Hyemin Han & Andrea L. Glenn - 2018 - Social Neuroscience 13 (3):257-267.
    In fMRI research, the goal of correcting for multiple comparisons is to identify areas of activity that reflect true effects, and thus would be expected to replicate in future studies. Finding an appropriate balance between trying to minimize false positives (Type I error) while not being too stringent and omitting true effects (Type II error) can be challenging. Furthermore, the advantages and disadvantages of these types of errors may differ for different areas of study. In many areas of social (...)
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  5. An fMRI Study Measuring Analgesia Enhanced by Religion as a Belief System.Katja Wiech, Miguel Farias, Guy Kahane, Nicholas Shackel, Wiebke Tiede & Irene Tracey - unknown
    Although religious belief is often claimed to help with physical ailments including pain, it is unclear what psychological and neural mechanisms underlie the influence of religious belief on pain. By analogy to other top-down processes of pain modulation we hypothesized that religious belief helps believers reinterpret the emotional significance of pain, leading to emotional detachment from it. Recent findings on emotion regulation support a role for the right ventrolateral prefrontal cortex, a region also important for driving top-down pain inhibitory circuits. (...)
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  6. GABAA Receptor Deficits Predict Recovery in Patients With Disorders of Consciousness: A Preliminary Multimodal [11C]Flumazenil PET and fMRI Study.Pengmin Qin, Georg Northoff, Timothy Lane & et al - 2015 - Human Brain Mapping:DOI: 10.1002/hbm.22883.
    Disorders of consciousness (DoC)—that is, unresponsive wakefulness syndrome/vegetative state and minimally conscious state—are debilitating conditions for which no reliable markers of consciousness recovery have yet been identified. Evidence points to the GABAergic system being altered in DoC, making it a potential target as such a marker.
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  7.  82
    The Structured Uses of Concepts as Tools: Comparing fMRI Experiments That Investigate Either Mental Imagery or Hallucinations.Eden T. Smith - 2018 - Dissertation, University of Melbourne
    Sensations can occur in the absence of perception and yet be experienced ‘as if’ seen, heard, tasted, or otherwise perceived. Two concepts used to investigate types of these sensory-like mental phenomena (SLMP) are mental imagery and hallucinations. Mental imagery is used as a concept for investigating those SLMP that merely resemble perception in some way. Meanwhile, the concept of hallucinations is used to investigate those SLMP that are, in some sense, compellingly like perception. This may be a difference of degree. (...)
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  8.  20
    Domain-General and Domain-Specific Patterns of Activity Support Metacognition in Human Prefrontal Cortex.Jorge Morales, Hakwan Lau & Stephen M. Fleming - 2018 - The Journal of Neuroscience 38 (14):3534-3546.
    Metacognition is the capacity to evaluate the success of one's own cognitive processes in various domains; for example, memory and perception. It remains controversial whether metacognition relies on a domain-general resource that is applied to different tasks or if self-evaluative processes are domain specific. Here, we investigated this issue directly by examining the neural substrates engaged when metacognitive judgments were made by human participants of both sexes during perceptual and memory tasks matched for stimulus and performance characteristics. By comparing patterns (...)
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  9. Measuring Away an Attentional Confound?Jorge Morales, Yasha Mouradi, Claire Sergent, Ned Block, Vincent Taschereau-Dumouchel, David Rosenthal, Piercesare Grimaldi & Hakwan Lau - 2017 - Neuroscience of Consciousness 3 (1):1-3.
    A recent fMRI study by Webb et al. (Cortical networks involved in visual awareness independent of visual attention, Proc Natl Acad Sci U S A 2016;113:13923–28) proposes a new method for finding the neural correlates of awareness by matching atten- tion across awareness conditions. The experimental design, however, seems at odds with known features of attention. We highlight logical and methodological points that are critical when trying to disentangle attention and awareness.
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  10. Altered Resting-State Functional Connectivity in Cortical Networks in Psychopathy.Carissa L. Philippi, Maia S. Pujara, Julian C. Motzkin, Joseph P. Newman, Kent A. Kiehl & Michael Koenigs - 2015 - The Journal of Neuroscience 35 (15):6068 – 6078.
    Psychopathy is a personality disorder characterized by callous antisocial behavior and criminal recidivism. Here we examine whether psychopathy is associated with alterations in functional connectivity in three large-scale cortical networks. Using fMRI in 142 adult male prison inmates, we computed resting-state functional connectivity using seeds from the default mode network, frontoparietal network, and cingulo-opercular network. To determine the specificity of our findings to these cortical networks, we also calculated functional connectivity using seeds from two comparison primary sensory networks: visual (...)
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  11. Cultural Influences on the Neural Correlate of Moral Decision Making Processes.Hyemin Han, Gary H. Glover & Changwoo Jeong - 2014 - Behavioural Brain Research 259:215-228.
    This study compares the neural substrate of moral decision making processes between Korean and American participants. By comparison with Americans, Korean participants showed increased activity in the right putamen associated with socio-intuitive processes and right superior frontal gyrus associated with cognitive control processes under a moral-personal condition, and in the right postcentral sulcus associated with mental calculation in familiar contexts under a moral-impersonal condition. On the other hand, American participants showed a significantly higher degree of activity in the bilateral anterior (...)
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  12. Functional Integration and the Mind.Jakob Hohwy - 2007 - Synthese 159 (3):315-328.
    Different cognitive functions recruit a number of different, often overlapping, areas of the brain. Theories in cognitive and computational neuroscience are beginning to take this kind of functional integration into account. The contributions to this special issue consider what functional integration tells us about various aspects of the mind such as perception, language, volition, agency, and reward. Here, I consider how and why functional integration may matter for the mind; I discuss a general theoretical framework, based on generative models, that (...)
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  13. Mechanisms and Model-Based Functional Magnetic Resonance Imaging.Mark Povich - 2015 - Philosophy of Science 82 (5):1035-1046.
    Mechanistic explanations satisfy widely held norms of explanation: the ability to manipulate and answer counterfactual questions about the explanandum phenomenon. A currently debated issue is whether any nonmechanistic explanations can satisfy these explanatory norms. Weiskopf argues that the models of object recognition and categorization, JIM, SUSTAIN, and ALCOVE, are not mechanistic yet satisfy these norms of explanation. In this article I argue that these models are mechanism sketches. My argument applies recent research using model-based functional magnetic resonance imaging, a novel (...)
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  14.  27
    Neurofeedback-Based Moral Enhancement and the Notion of Morality.Koji Tachibana - 2017 - The Annals of the University of Bucharest - Philosophy Series 66 (2):25-41.
    Some skeptics question the very possibility of moral bioenhancement by arguing that if we lack a widely acceptable notion of morality, we will not be able to accept the use of a biotechnological technique as a tool for moral bioenhancement. I will examine this skepticism and argue that the assessment of moral bioenhancement does not require such a notion of morality. In particular, I will demonstrate that this skepticism can be neutralized in the case of recent neurofeedback techniques. This goal (...)
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  15. Minding Mammals.Adam Shriver - 2006 - Philosophical Psychology 19 (4):433-442.
    Many traditional attempts to show that nonhuman animals are deserving of moral consideration have taken the form of an argument by analogy. However, arguments of this kind have had notable weaknesses and, in particular, have not been able to convince two kinds of skeptics. One of the most important weaknesses of these arguments is that they fail to provide theoretical justifications for why particular physiological similarities should be considered relevant. This paper examines recent empirical research on pain and, in particular, (...)
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  16. Associations Between Psychopathic Traits and Brain Activity During Instructed False Responding.Andrea L. Glenn, Hyemin Han, Yaling Yang, Adrian Raine & Robert A. Schug - 2017 - Psychiatry Research: Neuroimaging 266:123-137.
    Lying is one of the characteristic features of psychopathy, and has been recognized in clinical and diagnostic descriptions of the disorder, yet individuals with psychopathic traits have been found to have reduced neural activity in many of the brain regions that are important for lying. In this study, we examine brain activity in sixteen individuals with varying degrees of psychopathic traits during a task in which they are instructed to falsify information or tell the truth about autobiographical and non-autobiographical facts, (...)
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  17. Towards the Developmental Pathway of Face Perception Abilities in the Human Brain.Simon van Rysewyk - 2010 - In A. Freitas-Magalhães (ed.), ‘Emotional Expression: The Brain and the Face’ (V. II, Second Series). University of Fernando Pessoa Press. pp. 111-131.
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  18. Neural Processing of Moral Violations Among Incarcerated Adolescents with Psychopathic Traits.Carla L. Harenski, Keith A. Harenski & Kent A. Kiehl - 2014 - Developmental Cognitive Neuroscience 10:181–189.
    Neuroimaging studies have found that adult male psychopaths show reduced engagement of limbic and paralimbic circuitry while making moral judgments. The goal of this study was to investigate whether these findings extend to adolescent males with psychopathic traits. Functional MRI was used to record hemodynamic activity in 111 incarcerated male adolescents while they viewed unpleasant pictures that did or did not depict moral transgressions and rated each on “moral violation severity”. Adolescents were assessed for psychopathic traits using the Psychopathy Checklist-Youth (...)
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  19. Activity in Early Visual Areas Predicts Interindividual Differences in Binocular Rivalry Dynamics.Hiroyuki Yamashiro, Hiroki Yamamoto, Hiroaki Mano, Masahiro Umeda, Toshihiro Higuchi & Jun Saiki - 2014 - Journal of Neurophysiology 111:1190-1202.
    When dissimilar images are presented to the two eyes, binocular rivalry (BR) occurs, and perception alternates spontaneously between the images. Although neural correlates of the oscillating perception during BR have been found in multiple sites along the visual pathway, the source of BR dynamics is unclear. Psychophysical and modeling studies suggest that both low- and high-level cortical processes underlie BR dynamics. Previous neuroimaging studies have demonstrated the involvement of high-level regions by showing that frontal and parietal cortices responded time locked (...)
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  20. There and Up Again: On the Uses and Misuses of Neuroimaging in Psychology.Guillermo Del Pinal & Marco J. Nathan - 2013 - Cognitive Neuropsychology 30 (4):233-252.
    The aim of this article is to discuss the conditions under which functional neuroimaging can contribute to the study of higher cognition. We begin by presenting two case studies—on moral and economic decision making—which will help us identify and examine one of the main ways in which neuroimaging can help advance the study of higher cognition. We agree with critics that functional magnetic resonance imaging (fMRI) studies seldom “refine” or “confirm” particular psychological hypotheses, or even provide details of the (...)
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  21. How Do Narratives and Brains Mutually Influence Each Other? Taking Both the ‘Neuroscientific Turn’ and the ‘Narrative Turn’ in Explaining Bio-Political Orders.Machiel Keestra - manuscript
    Introduction: the neuroscientific turn in political science The observation that brains and political orders are interdependent is almost trivial. Obviously, political orders require brain processes in order to emerge and to remain in place, as these processes enable action and cognition. Conversely, every since Aristotle coined man as “by nature a political animal” (Aristotle, Pol.: 1252a 3; cf. Eth. Nic.: 1097b 11), this also suggests that the political engagements of this animal has likely consequences for its natural development, including the (...)
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  22. Punishment and Psychopathy: A Case-Control Functional MRI Investigation of Reinforcement Learning in Violent Antisocial Personality Disordered Men.Sarah Gregory, R. James Blair, Dominic Ffytche, Andrew Simmons, Veena Kumari, Sheilagh Hodgins & Nigel Blackwood - 2014 - Lancet Psychiatry 2:153–160.
    Background Men with antisocial personality disorder show lifelong abnormalities in adaptive decision making guided by the weighing up of reward and punishment information. Among men with antisocial personality disorder, modifi cation of the behaviour of those with additional diagnoses of psychopathy seems particularly resistant to punishment. Methods We did a case-control functional MRI (fMRI) study in 50 men, of whom 12 were violent off enders with antisocial personality disorder and psychopathy, 20 were violent off enders with antisocial personality disorder (...)
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  23.  53
    Brain Network Commonality and the General Empirical Method.Anuj Rastogi - 2014 - Dialogues in Philosophy, Mental and Neuro Sciences 7 (2):68-69.
    The Generalized Empirical Method as outlined by Henman initially seems a cogent approach that should be adopted by cognitive neuroscientists. However, some weaknesses in the presumptions of this method in light of modern neuroscience research may challenge its validity. As I am currently working on mapping cerebral-cerebellar networks using fMRI, I am intrigued by the practical utility of the GEM in experimental work.
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  24. Children with Reading Disability Show Brain Differences in Effective Connectivity for Visual, but Not Auditory Word Comprehension.Li Liu, Vira Amit, Emma Friedman & James Booth - 2010 - PLoS ONE 10.
    Background -/- Previous literature suggests that those with reading disability (RD) have more pronounced deficits during semantic processing in reading as compared to listening comprehension. This discrepancy has been supported by recent neuroimaging studies showing abnormal activity in RD during semantic processing in the visual but not in the auditory modality. Whether effective connectivity between brain regions in RD could also show this pattern of discrepancy has not been investigated. Methodology/Principal Findings -/- Children (8- to 14-year-olds) were given a semantic (...)
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  25. The Cross-Validation in the Dialogue of Mental and Neuroscience.Drozdstoj St Stoyanov - 2009 - Dialogues in Philosophy, Mental and Neuro Sciences 2 (1):24-28.
    The aim of the Validation Theory (VT) as a meta-empirical construct is to introduce a new vista in the reorganization of the neuroscience, in its role of a science of the Mind-and-Brain unification. The present study focuses on existing discrepancies and contradictions between the methods of basic neurosciences and those prescribed by the psychological science. Our view is that these discrepancies are based on a high penetration of traditional neuroscience methods into the biological processes, coupled with low extrapolation (experimenting with (...)
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