This essay considers how scholarly approaches to the development of molecular biology have too often narrowed the historical aperture to genes, overlooking the ways in which other objects and processes contributed to the molecularization of life. From structural and dynamic studies of biomolecules to cellular membranes and organelles to metabolism and nutrition, new work by historians, philosophers, and STS scholars of the life sciences has revitalized older issues, such as the relationship of life to matter, or of physicochemical inquiries to (...) biology. This scholarship points to a novel molecular vista that opens up a pluralist view of molecularizations in the twentieth century and considers their relevance to current science. (shrink)

The application of machine-learning technologies to medical practice promises to enhance the capabilities of healthcare professionals in the assessment, diagnosis, and treatment, of medical conditions. However, there is growing concern that algorithmic bias may perpetuate or exacerbate existing health inequalities. Hence, it matters that we make precise the different respects in which algorithmic bias can arise in medicine, and also make clear the normative relevance of these different kinds of algorithmic bias for broader questions about justice and fairness in healthcare. (...) In this paper, we provide the building blocks for an account of algorithmic bias and its normative relevance in medicine. (shrink)

Issues of reliability are claiming center-stage in the epistemology of machine learning. This paper unifies different branches in the literature and points to promising research directions, whilst also providing an accessible introduction to key concepts in statistics and machine learning – as far as they are concerned with reliability.

The history of philosophy is replete with attempts at invoking rationality as a means of directing and even subduing human desire and emotion. Understood as that which moves human beings to action, desire and emotion come to be associated with human freedom and rationality as a means of curbing that freedom. Plato, for instance, takes for granted a separation between thought and action that drives a wedge between our rational ability to exercise self-discipline and the free expression of desire and (...) emotion. Hobbes, on the other hand, replaces our internal ability for rational self-control with the external authority of the political State. So long as freedom and control are pitted against one another, human beings are incapable of attaining a symbiosis of these two elements of human action so essential to realizing true democracy. Unlike Plato, John Dewey sees in democracy the greatest potential for individual and social life. The purpose of this dissertation is to demonstrate how the educational philosophy of Dewey, which culminates in an educational aesthetic, appeals to and makes the most of the symbiosis of freedom and self-control, emotion and reason. Dewey’s educational aesthetic not only offers an alternative to traditional methods of education, but also demonstrates how the goal of a democratic way of life is made feasible by means of intelligently guided self-discipline—a form of self-control guided by intelligence that is not a constraint upon freedom, but instead embodies greater opportunity for freedom. I trace the basis for this synthesis, in the social-political and pedagogical principles of John Locke and Jean-Jacques Rousseau. Both Locke and Rousseau offer educational theories that begin turning our attention toward the essential partnership required of rationality and emotion. Dewey's educational aesthetic is then considered as a response to alienating forms of education that continue to pit control and freedom against one another, and which thwart the intellectual and emotional development necessary for autonomy and democratic forms of social organization. (shrink)

Past research has identified a number of asymmetries based on moral judgments. Beliefs about what a person values, whether a person is happy, whether a person has shown weakness of will, and whether a person deserves praise or blame seem to depend critically on whether participants themselves find the agent's behavior to be morally good or bad. To date, however, the origins of these asymmetries remain unknown. The present studies examine whether beliefs about an agent's “true self” explain these observed (...) asymmetries based on moral judgment. Using the identical materials from previous studies in this area, a series of five experiments indicate that people show a general tendency to conclude that deep inside every individual there is a “true self” calling him or her to behave in ways that are morally virtuous. In turn, this belief causes people to hold different intuitions about what the agent values, whether the agent is happy, whether he or she has shown weakness of will, and whether he or she deserves praise or blame. These results not only help to answer important questions about how people attribute various mental states to others; they also contribute to important theoretical debates regarding how moral values may shape our beliefs about phenomena that, on the surface, appear to be decidedly non-moral in nature. (shrink)

This study provides a unified theory of properties, relations, and propositions (PRPs). Two conceptions of PRPs have emerged in the history of philosophy. The author explores both of these traditional conceptions and shows how they can be captured by a single theory.

This paper constructs a model of metaphysical indeterminacy that can accommodate a kind of ‘deep’ worldly indeterminacy that arguably arises in quantum mechanics via the Kochen-Specker theorem, and that is incompatible with prominent theories of metaphysical indeterminacy such as that in Barnes and Williams (2011). We construct a variant of Barnes and Williams's theory that avoids this problem. Our version builds on situation semantics and uses incomplete, local situations rather than possible worlds to build a model. We evaluate the resulting (...) theory and contrast it with similar alternatives, concluding that our model successfully captures deep indeterminacy. (shrink)

The term “thematic analysis” abounds in research articles and appears in the titles of books, without the authors of these writings being primarily concerned with defining what thematic analysis is. Thematic analysis is present in the current vocabulary of several disciplines and is presented as a working method of choice in psychology, sociology, or linguistics, to name but a few. This article seeks to situate thematic analysis in the thinking of Holton Gerald, who introduced it into the philosophy of science (...) as a rational approach that can account for scientific discovery and progress. The aim of this article is to see whether the attested interdisciplinary interest nature of thematic analysis argues in favour or against Holton’s claim of making it a credible and acceptable tool in philosophy of science. (shrink)

The paper begins with a clarification of the notions of intuition (and, in particular, modal intuition), modal error, conceivability, metaphysical possibility, and epistemic possibility. It is argued that two-dimensionalism is the wrong framework for modal epistemology and that a certain nonreductionist approach to the theory of concepts and propositions is required instead. Finally, there is an examination of moderate rationalism’s impact on modal arguments in the philosophy of mind -- for example, Yablo’s disembodiment argument and Chalmers’s zombie argument. A less (...) vulnerable style of modal argument is defended, which nevertheless wins the same anti-materialist conclusions sought by these other arguments. (shrink)

The topic of a priori knowledge is approached through the theory of evidence. A shortcoming in traditional formulations of moderate rationalism and moderate empiricism is that they fail to explain why rational intuition and phenomenal experience count as basic sources of evidence. This explanatory gap is filled by modal reliabilism -- the theory that there is a qualified modal tie between basic sources of evidence and the truth. This tie to the truth is then explained by the theory of concept (...) possession: this tie is a consequence of what, by definition, it is to possess (i.e., to understand) one’s concepts. A corollary of the overall account is that the a priori disciplines (logic, mathematics, philosophy) can be largely autonomous from the empirical sciences. (shrink)

This paper provides a defense of two traditional theses: the Autonomy of Philosophy and the Authority of Philosophy. The first step is a defense of the evidential status of intuitions (intellectual seemings). Rival views (such as radical empiricism), which reject the evidential status of intuitions, are shown to be epistemically self-defeating. It is then argued that the only way to explain the evidential status of intuitions is to invoke modal reliabilism. This theory requires that intuitions have a certain qualified modal (...) tie to the truth. This result is then used as the basis of the defense of the Autonomy and Authority theses. The paper closes with a defense of the two theses against a potential threat from scientific essentialism. (shrink)

Radical empiricism is the view that a person's experiences (sensory and introspective), or a person's observations, constitute the person's evidence. This view leads to epistemic self-defeat. There are three arguments, concerning respectively: (1) epistemic starting points; (2) epistemic norms; (3) terms of epistemic appraisal. The source of self-defeat is traced to the fact that empiricism does not count a priori intuition as evidence (where a priori intuition is not a form of belief but rather a form of seeming, specifically intellectual (...) as opposed to sensory). Moderate rationalism, by contrast, avoids self-defeat. (shrink)

In this paper, I propose a framework that supports both free will and anomalous mind-matter interaction (psychokinesis). I begin by considering the argument by the physicist Sean Carroll that the laws of physics as we understand them rule out psychokinesis (and other modes of psi). I find Carroll’s claims problematic, in part due to what I believe are misunderstandings of arguments borrowed from David Hume. I proceed to consider a more dispositional notion of causality (in contrast to one characterized by (...) universal and necessary laws) which I argue is more hospitable to both psychokinesis and free will. I then incorporate recent work from the philosophy of mind and science to arrive at a framework that supports both real volition and psychokinesis, which I argue are intimately linked. This approach is fundamentally dispositional, but grounded in an ontologically prior field of awareness and potentiality. I also consider that the regularities (or causal natures) we observe in our physical world are ultimately supported by what we might term teleological “intentions” within a nonlocal, mind-like quantum ground. (shrink)

Scientific essentialism is the view that some necessities can be known only with the aid of empirical science. The thesis of the paper is that scientific essentialism does not extend to the central questions of philosophy and that these questions can be answered a priori. The argument is that the evidence required for the defense of scientific essentialism is reliable only if the intuitions required by philosophy to answer its central questions is also reliable. Included is an outline of a (...) modal reliabilist theory of basic evidence and a concept-possession account of the reliability of a priori intuition. (shrink)

Recent work in philosophy of language has raised significant problems for the traditional theory of propositions, engendering serious skepticism about its general workability. These problems are, I believe, tied to fundamental misconceptions about how the theory should be developed. The goal of this paper is to show how to develop the traditional theory in a way which solves the problems and puts this skepticism to rest. The problems fall into two groups. The first has to do with reductionism, specifically attempts (...) to reduce propositions to extensional entities-either extensional functions or sets. The second group concerns problems of fine grained content-both traditional 'Cicero'/'Tully' puzzles and recent variations on them which confront scientific essentialism. After characterizing the problems, I outline a non-reductionist approach-the algebraic approach-which avoids the problems associated with reductionism. I then go on to show how the theory can incorporate non-Platonic (as well as Platonic) modes of presentation. When these are implemented nondescriptively, they yield the sort of fine-grained distinctions which have been eluding us. The paper closes by applying the theory to a cluster of remaining puzzles, including a pair of new puzzles facing scientific essentialism. (shrink)

from the back cover: -/- "Searching the faraway origins of philosophy, religion, and science might reshape the accepted foundation of our knowledge. Georges Kassabgi invites us to think anew about starting points and primal elements, material as well as nonmaterial--common to all that exists. With this essay, he sketches a walkway, so often dreamed of but never completed before, connecting these three disciplines, so as to improve the outcome of discussions about some big questions." -/- -- Daniel S. Larange', PhD (...) McGill University, Montreal 2012. (shrink)

The persistent interpretation problem for quantum mechanics may indicate an unwillingness to consider unpalatable assumptions that could open the way toward progress. With this in mind, I focus on the work of David Bohm, whose earlier work has been more influential than that of his later. As I’ll discuss, I believe two assumptions play a strong role in explaining the disparity: 1) that theories in physics must be grounded in mathematical structure and 2) that consciousness must supervene on material processes. (...) I’ll argue that the first assumption appears to lead us toward Everett’s many worlds interpretation, which suggests a red flag. I’ll also argue that the second assumption is suspect due to the persistent explanatory gap for consciousness. Later, I explore ways that Bohm’s later work holds some promise in providing a better fit with our world, both phenomenologically and empirically. Also, I’ll address the possible problem of realism. (shrink)

The paper elaborates upon various points and arguments in the author’s “A Priori Knowledge and the Scope of Philosophy” (Philosophical Studies, 1993), in which the author defends the autonomy of philosophy from the empirical sciences. It provides, for example, an extended defense of the modal reliabilist theory of basic evidence, including a new argument against evolutionary explanations of the reliability of intuitions. It also contains a fuller discussion of how to neutralize the threat of scientific essentialism to the autonomy of (...) philosophy. (shrink)

This paper argues that participation in an intimate relationship can generate additional or stronger reasons for one to act paternalistically toward the intimate. Moreover, participation in such a relationship can also weaken or cancel some of the presumptive reasons of respect one would otherwise have not to interfere. The paper also reflects, more generally, on the nature of intimate relationships, the normative significance of paternalism, and the normative differences between paternalism in larger-scale institutional contexts and paternalism in closer, interpersonal ones. (...) -/- . (shrink)

In this paper, I consider what the growing evidence in parapsychology can tell us about the nature of consciousness. Parapsychology remains controversial because it implies deviations from the understanding that many scientists and philosophers hold about the nature of reality. However, given the difficulties in explaining consciousness, a growing number of philosophers have called for new, possibly radical explanations, which include versions of dualism or panpsychism. In this spirit, I briefly review the evidence on psi to see what explanation of (...) consciousness might best be supported. After a brief survey of the evidence, I conclude that the best explanation would probably be neutral monism. I then explore a framework for neutral monism, using well-known features of quantum mechanics, to develop a ground or bridge between consciousness and matter. This framework, which I believe helps explain the psi evidence, suggests that a non-local proto-conscious field of potential or seed stuff underlies both matter and consciousness. (shrink)

In this chapter we explore two important questions that we believe should be central to any discussion of the ethics and politics of cultural heritage: What are the harms associated with appropriation and commodification, specifically where the heritage of Indigenous peoples is concerned? And how can these harms best be avoided? Archaeological concerns animate this discussion; we are ultimately concerned with fostering postcolonial archaeological practices. But we situate these questions in a broader context, addressing them as they arise in connection (...) with the appropriation of Indigenous cultural heritage, both past and present. (shrink)

_Socrates_ presents a compelling case for some life-changing conclusions that follow from a close reading of Socrates' arguments. Offers a highly original study of Socrates and his thought, accessible to contemporary readers Argues that through studying Socrates we can learn practical wisdom to apply to our lives Lovingly crafted with humour, thought-experiments and literary references, and with close reading sof key Socratic arguments Aids readers with diagrams to make clear complex arguments.

Commonplace syntactic constructions in natural language seem to generate ontological commitments to a dazzling array of metaphysical categories - aggregations, sets, ordered n-tuples, possible worlds, intensional entities, ideal objects, species, intensive and extensive quantities, stuffs, situations, states, courses of events, nonexistent objects, intentional and discourse objects, general objects, plural objects, variable objects, arbitrary objects, vague kinds and concepts, fuzzy sets, and so forth. But just because a syntactic construction in some natural language appears to invoke a new category of entity, (...) are we theoreticians epistemically justified in holding that there are such entities? This would hardly seem sufficient. To be epistemically justified, the ontology to which we theoreticians are committed must pass strict standards: the entities must be of the sort required by our best comprehensive theory of the world. The thesis of this paper is that fine-grained type-free intensional entities are like this. If the thesis is right, these entities have a special objective status perhaps not possessed by some of the other ontological categories associated with special syntactic constructions in natural language. In fact, it is plausible to hold that fine-grained type-free intensional entities provide the proper minimal framework for constructing logical and linguistic theories. In this paper my strategy will be to survey the competing conceptions of fine-grained type-free intensionality and to present arguments in support of one of them. Following this narrowing down process, I will go on to the indicated epistemological considerations. (shrink)

Presented here is an argument for the existence of universals. Like Church's translation- test argument, the argument turns on considerations from intensional logic. But whereas Church's argument turns on the fine-grained informational content of intensional sentences, this argument turns on the distinctive logical features of 'that'-clauses embedded within modal contexts. And unlike Church's argument, this argument applies against truth-conditions nominalism and also against conceptualism and in re realism. So if the argument is successful, it serves as a defense of full (...) ante rem realism. The argument emphasizes the need for a unified treatment of intensional statements -- modal statements as well as statements of assertion and belief. The larger philosophical moral will be that ante rem universals are uniquely suited to carry a certain kind of modal information. Linguistic entities, mind-dependent universals, and instance-dependent universals are incapable of serving that function. (shrink)

It is argued that, because of scientific essentialism, two currently popular arguments against the mind-body identity thesis -- the multiple-realizability argument and the Nagel-Jackson knowledge argument -- are unsatisfactory as they stand and that their problems are incurable. It is then argued that a refutation of the identity thesis in its full generality can be achieved by weaving together two traditional Cartesian arguments -- the modal argument and the certainty argument. This argument establishes, not just the falsity of the identity (...) thesis, but also the metaphysical possibility of disembodiment. (shrink)

The paper investigates Ernst Cassirer’s structuralist account of geometrical knowledge developed in his Substanzbegriff und Funktionsbegriff. The aim here is twofold. First, to give a closer study of several developments in projective geometry that form the direct background for Cassirer’s philosophical remarks on geometrical concept formation. Specifically, the paper will survey different attempts to justify the principle of duality in projective geometry as well as Felix Klein’s generalization of the use of geometrical transformations in his Erlangen program. The second aim (...) is to analyze the specific character of Cassirer’s geometrical structuralism formulated in 1910 as well as in subsequent writings. As will be argued, his account of modern geometry is best described as a “methodological structuralism”, that is, as a view mainly concerned with the role of structural methods in modern mathematical practice. (shrink)

Functionalism would be mistaken if there existed a system of deviant relations (an “anti-mind”) that had the same functional roles as the standard mental relations. In this paper such a system is constructed, using “Quinean transformations” of the sort associated with Quine’s thesis of the indeterminacy of translation. For example, a mapping m from particularistic propositions (e.g., that there exists a rabbit) to universalistic propositions (that rabbithood is manifested). Using m, a deviant relation thinking* is defined: x thinks* p iff (...) x thinks m(p). Such deviant relations satisfy the commonly discussed functionalist psychological principles. Finally, a more complicated system of deviant relations is constructed, one satisfying sophisticated principles dealing with the self-conscious rational mind. (shrink)

Hilbert's ε-calculus is based on an extension of the language of predicate logic by a term-forming operator εx. Two fundamental results about the ε-calculus, the first and second epsilon theorem, play a rôle similar to that which the cut-elimination theorem plays in sequent calculus. In particular, Herbrand's Theorem is a consequence of the epsilon theorems. The paper investigates the epsilon theorems and the complexity of the elimination procedure underlying their proof, as well as the length of Herbrand disjunctions of existential (...) theorems obtained by this elimination procedure. (shrink)

This paper provides a new approach to a family of outstanding logical and semantical puzzles, the most famous being Frege's puzzle. The three main reductionist theories of propositions (the possible-worlds theory, the propositional-function theory, the propositional-complex theory) are shown to be vulnerable to Benacerraf-style problems, difficulties involving modality, and other problems. The nonreductionist algebraic theory avoids these problems and allows us to identify the elusive nondescriptive, non-metalinguistic, necessary propositions responsible for the indicated family of puzzles. The algebraic approach is also (...) used to defend antiexistentialism against existentialist prejudices. The paper closes with a suggestion about how this theory of content might enable us to give purely semantic (as opposed to pragmatic) solutions to the puzzles based on a novel formulation of the principle of compositionality. (shrink)

The inherently subjective nature of consciousness severely limits our ability to make progress on the problem of consciousness. The inability to acquire objective, publicly available data on the phenomenal aspect of consciousness makes evaluating alternative theories very difficult, if not impossible. However, the anomalous nature of subjective states with respect to our conventional theories of the physical world suggests the possibility of considering other anomalous data around consciousness that happen to be objective. For such purposes, I propose that we examine (...) the psi data gathered under laboratory conditions, which generally receive little attention. I wish to consider whether we have theories or frameworks of consciousness that attempt to account for subjective qualia but also fit the psi data. I argue that Russellian monism can be combined with an argument regarding quantum holism to arrive at a version of cosmopsychism that fits very well with the psi data. While I do not argue that such a framework exhausts the theoretical possibilities, I do suggest we can move forward with a framework that has attractive theoretical features and is also consistent with objective data currently on the table. (shrink)

Reber and Alcock have recently made a sharp attack on the entire psi literature, and in particular a recent overview by Cardeña of the meta-analyses across various categories of psi. They claim the data are inherently fl awed because of their disconnect with our current understanding of the world. As a result, they ignore the data and identify key scientific principles that they argue clash with psi. In this Commentary, I argue that these key principles are diffi cult to apply (...) in areas where our understanding remains poor, especially quantum mechanics and consciousness. I also explore how the psi data may fi t within these two domains. (shrink)

Philosophical interest in state power has tended to focus on the state’s coercive powers rather than its expressive powers. I consider an underexplored aspect of the state’s expressive capacity: its capacity to use symbols (such as monuments, memorials, and street names) to promote political ends. In particular, I argue that the liberal state’s deployment of symbols to promote its members’ commitment to liberal ideals is in need of special justification. This is because the state’s exercise of its capacity to use (...) symbols may be in tension with respecting individual autonomy, particularly in cases in which the symbols exert influence without engaging citizens’ rational capacities. But despite the fact that the state’s deployment of symbols may circumvent citizens’ rational capacities, I argue that it may nonetheless be permissible when surrounded by certain liberal institutions and brought about via democratic procedures. (shrink)

Throughout the debate on psi, skeptics have almost universally insisted on different standards for evaluating the evidence, claiming that psi represents a radical departure from our current scientific understanding. Thus, there is considerable ambiguity about what standard of evaluation psi must meet. Little attention has been paid to the possible harm to the integrity of scientific investigation from this resulting inconsistency in testing standards. Some have proposed using a Bayesian framework as an improvement on this dilemma in order to more (...) explicitly model beliefs, assumptions, and background scientific knowledge, especially when evaluating a controversial hypothesis. Recently, Kuhn’s notion of paradigms, which constrains scientific research within bound- aries believed to be most productive, has been incorporated into a Bayesian framework. Within this framework, I explore a likely paradigm or meta-theory used by skeptics that typically constrains research and makes it difficult for psi evidence to be accepted. It appears that such a paradigm would in many respects have difficulty accounting for consciousness, which is fundamental to an understanding of psi. I discuss why psi data are likely to play a key role in making progress in solving the problem of consciousness. Thus, applying different standards of evaluation to psi data is likely counterproductive. (shrink)

In this paper, I explore the link between consciousness and quantum mechanics. Often explanations that invoke consciousness to help explain some of the most perplexing aspects of quantum mechanics are not given serious attention. However, casual dismissal is perhaps unwarranted, given the persistence of the measurement problem, as well as the mysterious nature of consciousness. Using data accumulated from experiments in parapsychology, I examine what anomalous data with respect to consciousness might tell us about various explanations of quantum mechanics. I (...) examine three categories of quantum mechanics interpretations that have some promise of fitting with this anomalous data. I conclude that explanations that posit a substratum of reality containing pure information or potentia, along the lines proposed by Bohm and Stapp, off er the best fit for various categories of this data. (shrink)

The paper begins with an argument against eliminativism with respect to the propositional attitudes. There follows an argument that concepts are sui generis ante rem entities. A nonreductionist view of concepts and propositions is then sketched. This provides the background for a theory of concept possession, which forms the bulk of the paper. The central idea is that concept possession is to be analyzed in terms of a certain kind of pattern of reliability in one’s intuitions regarding the behavior of (...) the concept. The challenge is to find an analysis that is at once noncircular and fully general. Environmentalism, anti-individualism, holism, analyticity, etc. provide additional hurdles. The paper closes with a discussion of the theory’s implications for the Wittgenstein-Kripke puzzle about rule-following and the Benacerraf problem concerning mathematical knowledge. (shrink)

This is the only complete logic for properties, relations, and propositions (PRPS) that has been formulated to date. First, an intensional abstraction operation is adjoined to first-order quantifier logic, Then, a new algebraic semantic method is developed. The heuristic used is not that of possible worlds but rather that of PRPS taken at face value. Unlike the possible worlds approach to intensional logic, this approach yields a logic for intentional (psychological) matters, as well as modal matters. At the close of (...) the paper, the origin of incompleteness in logic is investigated. The culprit is found to be the predication relation, a relation on properties and relations that is expressed in natural language by the copula. (shrink)

We investigate an enrichment of the propositional modal language L with a "universal" modality ■ having semantics x ⊧ ■φ iff ∀y(y ⊧ φ), and a countable set of "names" - a special kind of propositional variables ranging over singleton sets of worlds. The obtained language ℒ $_{c}$ proves to have a great expressive power. It is equivalent with respect to modal definability to another enrichment ℒ(⍯) of ℒ, where ⍯ is an additional modality with the semantics x ⊧ ⍯φ (...) iff Vy(y ≠ x → y ⊧ φ). Model-theoretic characterizations of modal definability in these languages are obtained. Further we consider deductive systems in ℒ $_{c}$ . Strong completeness of the normal ℒ $_{c}$ logics is proved with respect to models in which all worlds are named. Every ℒ $_{c}$ -logic axiomatized by formulae containing only names (but not propositional variables) is proved to be strongly frame-complete. Problems concerning transfer of properties ([in]completeness, filtration, finite model property etc.) from ℒ to ℒ $_{c}$ are discussed. Finally, further perspectives for names in multimodal environment are briefly sketched. (shrink)