Achieving space situational awareness requires, at a minimum, the identification, characterization, and tracking of space objects. Leveraging the resultant space object data for purposes such as hostile threat assessment, object identification, and conjunction assessment presents major challenges. This is in part because in characterizing space objects we reference a variety of identifiers, components, subsystems, capabilities, vulnerabilities, origins, missions, orbital elements, patterns of life, operational processes, operational statuses, and so forth, which tend to be defined in highly heterogeneous and sometimes inconsistent (...) ways. The Space Domain Ontologies are designed to provide a consensus-based realist framework for formulating such characterizations in a way that is both consistent and computable. Space object data are aligned with classes and relations in a suite of ontologies built around the existing Space Object Ontology. They are stored in a dynamically updated Resource Description Framework triple store, which can be queried to support space situational awareness and the needs of spacecraft operators and analysts. This paper provides an overview of the Space Domain Ontologies and their development and use. It presents the motivation for and advantages of the Space Domain Ontologies, including the benefits they provide for enhancing and maintaining long-term space situational awareness. (shrink)

Achieving space domain awareness requires the identification, characterization, and tracking of space objects. Storing and leveraging associated space object data for purposes such as hostile threat assessment, object identification, and collision prediction and avoidance present further challenges. Space objects are characterized according to a variety of parameters including their identifiers, design specifications, components, subsystems, capabilities, vulnerabilities, origins, missions, orbital elements, patterns of life, processes, operational statuses, and associated persons, organizations, or nations. The Space Object Ontology provides a consensus-based realist framework (...) for formulating such characterizations in a computable fashion. Space object data are aligned with classes and relations in the Space Object Ontology and stored in a dynamically updated Resource Description Framework triple store, which can be queried to support space domain awareness and the needs of spacecraft operators. This paper presents the core of the Space Object Ontology, discusses its advantages over other approaches to space object classification, and demonstrates its ability to combine diverse sets of data from multiple sources within an expandable framework. Finally, we show how the ontology provides benefits for enhancing and maintaining longterm space domain awareness. (shrink)

We have begun work on two separate but related ontologies for the study of neurological diseases. The first, the Neurological Disease Ontology (ND), is intended to provide a set of controlled, logically connected classes to describe the range of neurological diseases and their associated signs and symptoms, assessments, diagnoses, and interventions that are encountered in the course of clinical practice. ND is built as an extension of the Ontology for General Medical Sciences — a high-level candidate OBO Foundry ontology that (...) provides a set of general classes that can be used to describe general aspects of medical science. ND is being built with classes utilizing both textual and axiomatized definitions that describe and formalize the relations between instances of other classes within the ontology itself as well as to external ontologies such as the Gene Ontology, Cell Ontology, Protein Ontology, and Chemical Entities of Biological Interest. In addition, references to similar or associated terms in external ontologies, vocabularies and terminologies are included when possible. Initial work on ND is focused on the areas of Alzheimer’s and other diseases associated with dementia, multiple sclerosis, and stroke and cerebrovascular disease. Extensions to additional groups of neurological diseases are planned. The second ontology, the Neuro-Psychological Testing Ontology (NPT), is intended to provide a set of classes for the annotation of neuropsychological testing data. The intention of this ontology is to allow for the integration of results from a variety of neuropsychological tests that assay similar measures of cognitive functioning. Neuro-psychological testing is an important component in developing the clinical picture used in the diagnosis of patients with a range of neurological diseases, such as Alzheimer’s disease and multiple sclerosis, and following stroke or traumatic brain injury. NPT is being developed as an extension to the Ontology for Biomedical Investigations. (shrink)

The Neurological Disease Ontology (ND) is being developed to provide a comprehensive framework for the representation of neurological diseases (Diehl et al., 2013). ND utilizes the model established by the Ontology for General Medical Science (OGMS) for the representation of entities in medicine and disease (Scheuermann et al., 2009). The goal of ND is to include information for each disease concerning its molecular, genetic, and environmental origins, the processes involved in its etiology and realization, as well as its clinical presentation (...) including signs and symptoms. (shrink)

We are developing the Neurological Disease Ontology (ND) to provide a framework to enable representation of aspects of neurological diseases that are relevant to their treatment and study. ND is a representational tool that addresses the need for unambiguous annotation, storage, and retrieval of data associated with the treatment and study of neurological diseases. ND is being developed in compliance with the Open Biomedical Ontology Foundry principles and builds upon the paradigm established by the Ontology for General Medical Science (OGMS) (...) for the representation of entities in the domain of disease and medical practice. Initial applications of ND will include the annotation and analysis of large data sets and patient records for Alzheimer’s disease, multiple sclerosis, and stroke. (shrink)

This paper provides a method for characterizing space events using the framework of conceptual spaces. We focus specifically on estimating and ranking the likelihood of collisions between space objects. The objective is to design an approach for anticipatory decision support for space operators who can take preventive actions on the basis of assessments of relative risk. To make this possible our approach draws on the fusion of both hard and soft data within a single decision support framework. Contextual data is (...) also taken into account, for example data about space weather effects, by drawing on the Space Domain Ontologies, a large system of ontologies designed to support all aspects of space situational awareness. The framework is coupled with a mathematical programming scheme that frames a mathematically optimal approach for decision support, providing a quantitative basis for ranking potential for collision across multiple satellite pairs. The goal is to provide the broadest possible information foundation for critical assessments of collision likelihood. (shrink)

The overall goal of the approach developed in this paper is to estimate the likelihood of a given kinetic kill scenario between hostile spacebased adversaries using the mathematical framework of Complex Conceptual Spaces Single Observation. Conceptual spaces are a cognitive model that provide a method for systematically and automatically mimicking human decision making. For accurate decisions to be made, the fusion of both hard and soft data into a single decision framework is required. This presents several challenges to this data (...) fusion framework. The first is the challenge involved in handling multiple complex terminologies, which is addressed by drawing on a set of Space Domain Ontologies. Another challenge is the complex combinatorics involved when considering all possible feature combinations. This can be mitigated by using integer linear programming optimization that is outlined by the Complex Conceptual Spaces Single Observation mathematical model framework. A third challenge is the complicated physics that is involved in a spacecraft collision that must be addressed to obtain a better understanding of threat assessment. Overcoming these various challenges allows for a quantitative ranking for the potential of a kinetic kill collision across multiple spacecraft pairs. In addition to overcoming these challenges this paper will break down threat assessment into four domains and identify a ranking of threat both for each individual domain and for the four domains combined. Simulation results are shown to verify the developed concepts. (shrink)

Despite the frequency of stillbirths, the subsequent implications are overlooked and underappreciated. We present findings from comprehensive, systematic literature reviews, and new analyses of published and unpublished data, to establish the effect of stillbirth on parents, families, health-care providers, and societies worldwide. Data for direct costs of this event are sparse but suggest that a stillbirth needs more resources than a livebirth, both in the perinatal period and in additional surveillance during subsequent pregnancies. Indirect and intangible costs of stillbirth are (...) extensive and are usually met by families alone. This issue is particularly onerous for those with few resources. Negative effects, particularly on parental mental health, might be moderated by empathic attitudes of care providers and tailored interventions. The value of the baby, as well as the associated costs for parents, families, care providers, communities, and society, should be considered to prevent stillbirths and reduce associated morbidity. (shrink)

Biological ontologies are used to organize, curate, and interpret the vast quantities of data arising from biological experiments. While this works well when using a single ontology, integrating multiple ontologies can be problematic, as they are developed independently, which can lead to incompatibilities. The Open Biological and Biomedical Ontologies Foundry was created to address this by facilitating the development, harmonization, application, and sharing of ontologies, guided by a set of overarching principles. One challenge in reaching these goals was that the (...) OBO principles were not originally encoded in a precise fashion, and interpretation was subjective. Here we show how we have addressed this by formally encoding the OBO principles as operational rules and implementing a suite of automated validation checks and a dashboard for objectively evaluating each ontology’s compliance with each principle. This entailed a substantial effort to curate metadata across all ontologies and to coordinate with individual stakeholders. We have applied these checks across the full OBO suite of ontologies, revealing areas where individual ontologies require changes to conform to our principles. Our work demonstrates how a sizable federated community can be organized and evaluated on objective criteria that help improve overall quality and interoperability, which is vital for the sustenance of the OBO project and towards the overall goals of making data FAIR. Competing Interest StatementThe authors have declared no competing interest. (shrink)

Host-microbiome interactions (HMIs) are critical for the modulation of biological processes and are associated with several diseases, and extensive HMI studies have generated large amounts of data. We propose that the logical representation of the knowledge derived from these data and the standardized representation of experimental variables and processes can foster integration of data and reproducibility of experiments and thereby further HMI knowledge discovery. A community-based Ontology of Host-Microbiome Interactions (OHMI) was developed following the OBO Foundry principles. OHMI leverages established (...) ontologies to create logically structured representations of microbiomes, microbial taxonomy, host species, host anatomical entities, and HMIs under different conditions and associated study protocols and types of data analysis and experimental results. (shrink)

This paper argues that higher-order doubt generates an epistemic dilemma. One has a higher-order doubt with regards to P insofar as one justifiably withholds belief as to what attitude towards P is justified. That is, one justifiably withholds belief as to whether one is justified in believing, disbelieving, or withholding belief in P. Using the resources provided by Richard Feldman’s recent discussion of how to respect one’s evidence, I argue that if one has a higher-order doubt with regards to P, (...) then one is not justified in having any attitude towards P. Otherwise put: No attitude towards the doubted proposition respects one’s higher-order doubt. I argue that the most promising response to this problem is to hold that when one has a higher-order doubt about P, the best one can do to respect such a doubt is to simply have no attitude towards P. Higher-order doubt is thus much more rationally corrosive than non-higher-order doubt, as it undermines the possibility of justifiably having any attitude towards the doubted proposition. (shrink)

Introduction Current treatments for pain have limited benefits and worrying side effects. Some studies suggest that pain is reduced when clinicians deliver positive messages. However, the effects of positive messages are heterogeneous and have not been subject to meta-analysis. We aimed to estimate the efficacy of positive messages for pain reduction. -/- Methods We included randomized trials of the effects of positive messages in a subset of the studies included in a recent systematic review of context factors for treating pain. (...) Several electronic databases were searched. Reference lists of relevant studies were also searched. Two authors independently undertook study selection, data extraction, risk of bias assessment, and analyses. Our primary outcome measures were differences in patient- or observer-reported pain between groups who were given positive messages and those who were not. -/- Results Of the 16 randomized trials (1703 patients) that met the inclusion criteria, 12 trials had sufficient data for meta-analysis. The pooled standardized effect size was −0.31 (95% confidence interval [CI] −0.61 to −0.01, p = 0.04, I2 = 82%). The effect size remained positive but not statistically significant after we excluded studies considered to have a high risk of bias (standard effect size −0.17, 95% CI −0.54 to 0.19, P = 0.36, I2 = 84%). -/- Conclusion Care of patients with chronic or acute pain may be enhanced when clinicians deliver positive messages about possible clinical outcomes. However, we have identified several limitations of the present study that suggest caution when interpreting the results. We recommend further high-quality studies to confirm (or falsify) our result. -/- FUNDING -/- Alexander Mebius research has been funded through the ERC grant "Philosophy of Pharmacology: Safety, Statistical Standards, and Evidence Amalgamation" (GA: 639276). (shrink)

El concepto de familia a lo largo de la historia ha sido estructurado y entendido desde diversas ópticas y perspectivas, configuradas especialmente a partir de los enfoques filosóficos, políticos, religiosos y sociales de cada época. Como señala Morales Gómez (2015), la familia, “es la institución histórica y jurídica de más profundo arraigo a lo largo de las distintas etapas de la civilización y su origen se remonta a los albores de la humanidad” (p. 129), pero, a pesar de ser una (...) institución como tal no se gesta a través de la norma, ya que su existencia es de carácter natural, y, lo que fundamenta y promueve la protección de su permanencia son sus fines intrínsecos. Las reflexiones desarrolladas en la época medieval y en los primeros siglos del cristianismo por grandes pensadores como san Agustín y Santo Tomás, cuyos aportes contribuyeron significativamente en la construcción de un modelo de familia basado en la sacramentalidad matrimonial, la educación en la fe y la formación en virtudes cristianas, cobran especial importancia en este recorrido. (shrink)

Some time ago, Joel Katzav and Brian Ellis debated the compatibility of dispositional essentialism with the principle of least action. Surprisingly, very little has been said on the matter since, even by the most naturalistically inclined metaphysicians. Here, we revisit the Katzav–Ellis arguments of 2004–05. We outline the two problems for the dispositionalist identified Katzav in his 2004 , and claim they are not as problematic for the dispositional essentialist at it first seems – but not for the reasons espoused (...) by Ellis. (shrink)

SUMMARY. The works of Alexander of Aphrodisias were written a few decades after the publication of the most successful -astrology hand- book in antiquity, Ptolemy's Tetrabiblos Syntaxis, which attempts to naturalize astrology, i.e. to make it agree with Aristotelian theory of science. A comparison of the doctrines between the Tetrabiblos and some passages of Alexander'p works on fate demostrates a noteworthy con¬vergere of the two scholars, and probably a dependence of the lasi great greek Aristotle's exegete on the (...) theories of Ptolemaic astrology, at least in reference to three points: theory of fate; justification of de- vining as a technical and naturai conjecture about man's fate; ana¬lysis of the stars' influence on the sublunary world in physical and phi¬losophical terms. (shrink)

This is a review of: Николай Онуфриевич Лосский, под редакцией В. П. Филатова, Москва: Росспэн (Серия "Философия России первой половины ХХ века"), 2016. It describes and appraises the content of this collection of nineteen articles on the life and thought of the prominent twentieth century Russian philosopher Nikolai Lossky. The volume, edited by Vladimir Filatov, presents the reader with an analysis of Lossky's philosophical legacy, including such aspects of his thought as his intuitivism, his personalism, his relation to phenomenology, his (...) narrative of the history of Russian philosophy, and so on. Lossky is also compared to other Russian philosophers (Shpet, Frank) and his legacy in other countries (Poland, Slovakia) is examined. The authors are Piama Gaidenko, Frances Nethercott, Albert Novikov, Victor Molchanov, Vitaly Lechtzer, Tatiana Shchedrina, Irina Beshkareva, Anatoly Pushkarsky, Elena Serdyukova, Vasily Vanchugov, Irina Blauberg, Roman Granin, Varvara Popova, Evgeny Babosov, Teresa Obolevich, Zlatica Plašienková, Oleg Ermichin, Alexander Podoxenov, Alexander Opalev, and Vladimir Schultz. (shrink)

Wall, G. Locke's attack on innate knowledge.--Harris, J. Leibniz and Locke on innate ideas.--Greenlee, D. Locke's idea of idea.--Aspelin, G. Idea and perception in Locke's essay.--Greenlee, D. Idea and object in the essay.--Mathews, H. E. Locke, Malebranche and the representative theory.--Alexander, P. Boyle and Locke on primary and secondary qualities.--Ayers, M. R. The ideas of power and substance in Locke's philosophy.--Allison, H. E. Locke's theory of personal identity.--Kretzmann, N. The main thesis of Locke's semantic theory.--Woozley, A. D. Some remarks (...) on Locke's account of knowledge.--Laudan, L. The nature and sources of Locke's views on hypotheses. (shrink)

ABSTRACT The individual-community relationship has always been one of the most fundamental topics of social sciences. In sociology, this is known as the micro-macro relationship while in economics it refers to the processes, through which, individual actions lead to macroeconomic phenomena. Based on philosophical discourse and systems theory, many sociologists even use the term "emergence" in their understanding of micro-macro relationship, which refers to collective phenomena that are created by the cooperation of individuals, but cannot be reduced to individual actions. (...) "Emergence" theories attempt to explain the nature of society as a complex system by examining how individuals and their relationships lead to the creation of integrated and macro-social phenomena such as markets, educational systems, cultural beliefs, and shared social practices. As a prelude to activity, every researcher has to answer the question from the methodological point of view, how is it possible to study the behavior of social groups and how can we gain knowledge about the laws related to social groups? Anyone who deals with humanities and social sciences or any reality and phenomenon that affects human beings, inevitably deals with the reality that is emerging. In fact, emergence occurs when one level of reality emerges radically from another level. Examples of emergent levels of reality include how the mind emerges from the body; or the way society emerges from human beings. Therefore, when there is an emerging factor, different scientific disciplines should be used, because it is inevitable to talk about social affairs, psychology and neurobiology, as well as physical and even chemical. -/- INTRODUCTION Since its beginning in the 19th century, sociology has faced the fundamental question of what a social phenomena stands for? At a glance, sociologists deal with the study of social groups, collective behavior, institutions, social structures, social networks, and social dynamics, and ultimately all such phenomena are composed of individuals. Therefore, social phenomena seem to have no independent ontological status, and in this case, sociology is ultimately about reducible individuals. Different approaches about the micro-macro relationship, using the concept of "emergence", argue that although collective phenomena are created by individuals, they cannot be reduced to individual action. The term "emergence" is used to distinguish "emergent results" from " Procedural results". Results are called Procedural that can only be calculated by adding or subtracting the causes that act together. On the contrary, they are emergent outcomes that are qualitatively novel compared to the causes from which they originate. An example of such emergent results is mental characteristics that emerge from neural processes, but are not considered among the characteristics of neural processes of components - which are their origin. Philosophical debates about emergentism and reductionism focus on the mind-brain relationship, but as many philosophers have noted, they can be generalized to apply to any hierarchical set of features. The cognitive revolution reactivated a 19th century controversy between theorists of Identity and dualism. The theorists of Identity believe in reductionist materialism and elimination of metaphysics, according to which the mind is nothing more than the biological, while the dualists believe that the mind and the brain are distinct from each other. Emergence has been considered as a third way between the theories of Identity and dualism. -/- METHODOLOGY Interdisciplinarity Is fundamentally indicated by the dominance of open systems as well as social and emerging systems at different levels. Therefore, as long as we are facing a new emergentism, there will necessarily be different fields and an interdisciplinary method. The commonality of social sciences and cognitive sciences on the issue of emergence provides the possibility of interaction and exchange of concepts between these two for deeper research. Therefore, in this research, apart from the concepts of Subvenience and downward causation, we have used multiple realization and wildly disjunctive, which are used to explain the emerging concept in cognitive sciences, including neurobiology, psychology, and philosophy. For analytical and interdisciplinary approaches, after examining the concepts of subvenience, and wildly disjunctive, Individualistic and collectivist emergentism have been reviewed. And then their adequacy is criticized and evaluated in meeting strong emergence conditions. -/- FINDINGS Philosophers of the mind have been able to define the conditions of irreducibility and downward causation, which are essential for strong emergence, by using the principle of subvenience with the help of multiple realization and wildly disjunctive principles. Therefore, by definition, emergentist individualism suffers from the problem of how to explain downward causality and irreducibility, and emergentist collectivism faces the challenge of reification. The analysis of the challenges facing the two methodological approaches of individualism and collectivism leads us to three unresolved issues about the emerging phenomenon, which are realism, downward causality, and mechanism. Despite the differences in the stances of these two approaches regarding the aforementioned triple problems, individualists and collectivists both agree that some social characteristics are reducible; and some others are irreducible due to their complexity, the determination of which, depends on the case study of the mechanism of emergence of each social characteristic. -/- CONCLUSION An emergence that is consistent with reductionism is called a weak emergence. And strong emergence includes the principle of irreducibility and downward causality. According to strong emergence, the characteristics of social phenomena have downward causal power, which cannot be reduced to the causal forces. The principle of subvenience, together with multiple realization and wildly disjunctive, can provide the conditions of irreducibility and downward causality, which are essential conditions of strong emergence. Based on the philosophical analysis of two methodological approaches, individualist and collectivist, it can be concluded that emergentist individualism suffers from the problem of how to explain downward causality and irreducibility, and reification collectivism faces the challenge of reification. The analysis of the problems faced by these two approaches leads us to three unresolved issues, which are realism, downward causality, and mechanism. individualist emergentists acknowledge the existence of emergent social characteristics, but despite this, they believe that these characteristics are not real but merely analytical constructs that require explanation based on individuals and their mutual actions. But collectivists argue that emergentism yields a categorical ontology and supports social realism. They accept the dependence of social characteristics on individuals, but claim that social entities and structures are ontologically independent. Individualists and collectivists both agree that some social characteristics are reducible; and others are irreducible due to their complexity; and the only way to recognize this is to engage in empirical studies of the mechanisms and temporal processes of "emergence" that create social characteristics. -/- NOVELTY The newness of this compact article is as follows: a) Presenting an interdisciplinary approach using the analysis of philosophy of cognitive sciences, including the philosophy of mind, neurobiology and psychology to formulate the issue of social emergence; b) Criticizing individualist and collectivist methodological approaches to the issue of social emergence and explaining the sufficiency and shortcomings of both in providing weak and strong emerging conditions; c) Explaining and categorizing the challenges facing methodological approaches in explaining the phenomenon of social emergence, in three categories: realism, downward causality, and mechanism. BIBLIOGRAPHY Beckermann, A., Flohr, H., & Kim, J. (eds.) (1992). Emergence or reduction? Essays on the prospects of nonreductive physicalism. Berlin: Walter de Gruyter. Bhaskar, R. (1979). The possibility of Naturalism. New York: Routledge. Bhaskar, R., Danermark, B. & Price, L. (2018). Interdisciplinarity and wellbeing: A critical realist general theory of interdisciplinarity. London and New York: Routledge. Blau, P.M. (1981). Introduction: diverse views of social structure and their common denominator. In Blau, P.M. & Merton, R.K. (eds.), Continuity in Structural Inquiry (pp. 1–23). Beverly Hills: Sage. Blau, P.M. (1987). Microprocess and macrostructure. In K.S. Cook (ed.), Social Exchange Theory (pp. 83–100). Newbury Park, CA: Sage. Brooks, R.A., & Maes, P. (eds). (1994). Artificial life IV; proceedings of the Fourth International Workshop on the Synthesis and Simulation of Living Systems. Cambridge, Mass: MIT Press. Clark, A. (1997). Being there: Putting brain, body, and world together again. Cambridge, Mass.: MIT Press. Coleman, J. S. (1987). Microfoundations and macrosocial behavior. In: J. C. Alexander, B. Giesen, R. Munch, & Neil J. Smelser (Eds.). The Micro-Macro Link (pp. 153–73). Berkeley: University of California. Coleman, J. S. (1990). Foundations of social theory. Cambridge, MA: Harvard University Press. Elster, J. (1985). Making sense of Marx. New York: Cambridge University Press. Fodor, J.A. (1974). Special sciences (Or: The disunity of science as a working hypothesis). Synthese, 28(2), 97–115. Fodor, J.A. (1989). Making mind matter more. Philosophical Topics, 17, 59-79. Giddens, A. (1984). The constitution of society: Outline of the theory of structuration. Berkeley: University of California Press. Hempel, C.G. (1965). Aspects of scientific explanation and other essays in the philosophy of science. New York: The Free Press. Horgan, T. (1993). From supervenience to superdupervenience: meeting the demands of a material world. Mind, 102, 555-586. Humphreys, P. (1997). How properties emerge”. Philosophy of Science, 64, 1-17. Kim, J. (1999). Making sense of emergence. Philosophical Studies, 95, 3–36. Kincaid, H. (1997). Individualism and the unity of science. New York: Rowman & Littlefield. Lewis, D.K. (1986). The plurality of worlds. Oxford: Oxford University Press. Nigel, G., & Conte, R. (eds.) (1995). Artificial societies; The computer simulation of social life. London: UCL Press. O’Connor, T. (1994). Emergent properties. American Philosophical Quarterly, 31, 91-104. Popper, K.R. (1968). Conjectures and refutations: The Growth of Scientific Knowledge. New York: Harper & Row. Sawyer, R. K. (2001). Emergence in sociology: contemporary philosophy of mind and some implications for sociological theory. American Journal of Sociology, 107, 551-585. Sawyer, R. K. (2004). The mechanisms of emergence. Philosophy of the Social Sciences, 34, 260–282. Sawyer, R. K. (2005). Social emergence: societies as complex systems. Cambridge: Cambridge University Press. Sawyer, R.K. (2003). Nonreductive individualism: Part 2, Social causation. Philosophy of the Social Sciences, 33, 203–224. Winch, P. (1993). The idea of a social science and its relation to philosophy‭ (SAMT, Trans.). Tehran, Iran: SAMT. (shrink)

Recent work has argued that there may be cases where no attitude – including withholding – is rationally permissible. In this paper, I consider two such epistemic dilemmas, John Turri’s Dilemma from Testimony and David Alexander’s Dilemma from Doubt. Turri presents a case where one’s only evidence rules out withholding (without warranting belief or disbelief). Alexander presents a case where higher order doubt means one must withhold judgment over whether withholding judgment is rational. In both cases, the authors (...) conclude that no doxastic attitude is warranted. In this paper, I argue against the possibility of these epistemic dilemmas. I argue that withholding cannot be irrational in either case. But meditating on the dilemmas gives us an important – and overlooked – insight into the nature of rational withholding. First, rational withholding is a function of evidence failing to sufficiently support belief or disbelief. As a result, withholding is not symmetrical to belief and disbelief. Second, there can be two distinct grounds for rational withholding. First, propositional withholding, which arises when our evidence does not support belief or disbelief in p. And second, doxastic withholding, which arises when we cannot determine whether our evidence supports belief or disbelief in p. Accepting two grounds of rational withholding licenses a kind of Weak Permissivism. But this Weak Permissivism should not be troubling to anyone. (shrink)

Öz: Frege özel adların (ve diğer dilsel simgelerin) anlamları ve gönderimleri arasında ünlü ayrımını yaptığı “Anlam ve Gönderim Üzerine” (1948) adlı makalesinde, bu ayrımın önemi, gerekliliği ve sonuçları üzerine uzun değerlendirmeler yapar ancak özel adın anlamından tam olarak ne anlaşılması gerektiğinden yalnızca bir dipnotta kısaca söz eder. Örneğin “Aristoteles” özel adının anlamının Platon’un öğrencisi ve Büyük İskender’in öğretmeni ya da Stagira’da doğan Büyük İskender’in öğretmeni olarak alınabileceğini söyler. Burada dikkat çeken nokta örnekteki özel adın olası anlamları olarak gösterilen belirli betimlemelerin (...) de özel ad içeriyor olması. Anlamın Frege için bileşimsel olduğu, bir başka deyişle bir dilsel simgenin anlamının (varsa) parçalarının anlamlarınca belirlendiği düşünülürse, örnekteki belirli betimlemelerin anlamlarının saptanabilmesi için içerdikleri özel adların da anlamları saptanıp betimleme içinde geçtikleri yere konmalıdır. Bu işlem hiçbir özel ad kalmayana kadar sürdürülmelidir. Ancak biraz düşünülünce bir özel adın nesnesini tekil olarak betimleyecek ve içinde özel ad geçmeyecek bir betimleme bulmanın kolay olmadığı görülür. Örneğin yukarıdaki betimlemelerde geçen “Platon”, “Büyük İskender” ve “Stagira” gibi özel adların anlamları olabilecek ancak özel ad içermeyen betimlemeler bulmak pek kolay görünmüyor. Ortaya bir sonsuz gerileme sorunu çıkmış gibi duruyor. Frege’nin anlam-gönderim ayrımını için ciddi sonuçları olabilecek bu sorunu Frege çözebilir mi? Bu yazıda bu sorunun yanıtını arayacağım. Sorunu betimledikten sonra Frege’nin önündeki seçenekleri (örneğin bağlama duyarlı terimlerden (gösterme adılları veya belirteçler) yararlanma veya bağlamı sınırlama gibi) değerlendireceğim. -/- Abstract: In his “Sense and Reference” (1948), Frege makes his famous distinction between the sense and the reference of a proper name (and other signs) and discusses at length the significance, necessity and consequences of the distinction, but he explains how the sense of a proper name should be understood very briefly in a footnote. According to him, for example, the sense of the proper name “Aristotle” can be taken as the pupil of Plato and teacher of Alexander the Great or the teacher of Alexander the Great who was born in Stagira. What is interesting here is that the definite descriptions given as the possible senses of this proper name do themselves contain proper names too. Since the sense is something compositional for Frege, which means the sense of a linguistic sign is determined by its constituents (if there are any), in order to determine the sense of definite descriptions in question, we should first determine the senses of proper names they contain and substitute these senses with the proper names themselves. This process should continue until no proper name remains. However, it does not seem easy to find a definite description which describes the object of a proper name uniquely but contains no proper name itself. For instance, could we find appropriate senses that contain no proper name for “Plato”, “Alexander the Great” and “Stagira”? It does not seem likely. A problem of infinite regress appears to arise. Can Frege solve this problem, which poses a serious threat for his sensereference distinction? I will explore this problem in this paper. After explaining the problem, I will discuss the options (e.g. turning to indexicals or context restriction) Frege can take to deal with it. (shrink)

This seventh volume of Collected Papers includes 70 papers comprising 974 pages on (theoretic and applied) neutrosophics, written between 2013-2021 by the author alone or in collaboration with the following 122 co-authors from 22 countries: Mohamed Abdel-Basset, Abdel-Nasser Hussian, C. Alexander, Mumtaz Ali, Yaman Akbulut, Amir Abdullah, Amira S. Ashour, Assia Bakali, Kousik Bhattacharya, Kainat Bibi, R. N. Boyd, Ümit Budak, Lulu Cai, Cenap Özel, Chang Su Kim, Victor Christianto, Chunlai Du, Chunxin Bo, Rituparna Chutia, Cu Nguyen Giap, Dao (...) The Son, Vinayak Devvrat, Arindam Dey, Partha Pratim Dey, Fahad Alsharari, Feng Yongfei, S. Ganesan, Shivam Ghildiyal, Bibhas C. Giri, Masooma Raza Hashmi, Ahmed Refaat Hawas, Hoang Viet Long, Le Hoang Son, Hongbo Wang, Hongnian Yu, Mihaiela Iliescu, Saeid Jafari, Temitope Gbolahan Jaiyeola, Naeem Jan, R. Jeevitha, Jun Ye, Anup Khan, Madad Khan, Salma Khan, Ilanthenral Kandasamy, W.B. Vasantha Kandasamy, Darjan Karabašević, Kifayat Ullah, Kishore Kumar P.K., Sujit Kumar De, Prasun Kumar Nayak, Malayalan Lathamaheswari, Luong Thi Hong Lan, Anam Luqman, Luu Quoc Dat, Tahir Mahmood, Hafsa M. Malik, Nivetha Martin, Mai Mohamed, Parimala Mani, Mingcong Deng, Mohammed A. Al Shumrani, Mohammad Hamidi, Mohamed Talea, Kalyan Mondal, Muhammad Akram, Muhammad Gulistan, Farshid Mofidnakhaei, Muhammad Shoaib, Muhammad Riaz, Karthika Muthusamy, Nabeela Ishfaq, Deivanayagampillai Nagarajan, Sumera Naz, Nguyen Dinh Hoa, Nguyen Tho Thong, Nguyen Xuan Thao, Noor ul Amin, Dragan Pamučar, Gabrijela Popović, S. Krishna Prabha, Surapati Pramanik, Priya R, Qiaoyan Li, Yaser Saber, Said Broumi, Saima Anis, Saleem Abdullah, Ganeshsree Selvachandran, Abdulkadir Sengür, Seyed Ahmad Edalatpanah, Shahbaz Ali, Shahzaib Ashraf, Shouzhen Zeng, Shio Gai Quek, Shuangwu Zhu, Shumaiza, Sidra Sayed, Sohail Iqbal, Songtao Shao, Sundas Shahzadi, Dragiša Stanujkić, Željko Stević, Udhayakumar Ramalingam, Zunaira Rashid, Hossein Rashmanlou, Rajkumar Verma, Luige Vlădăreanu, Victor Vlădăreanu, Desmond Jun Yi Tey, Selçuk Topal, Naveed Yaqoob, Yanhui Guo, Yee Fei Gan, Yingcang Ma, Young Bae Jun, Yuping Lai, Hafiz Abdul Wahab, Wei Yang, Xiaohong Zhang, Edmundas Kazimieras Zavadskas, Lemnaouar Zedam. (shrink)

REPRODUÇÃO EM NOVILHAS LEITEIRAS -/- INTRODUÇÃO -/- O principal objetivo da criação de substitutos em gado leiteiro é produzir uma novilha que tenha seu parto aos dois anos de idade (23 a 25 meses) e com um peso de 550 a 580 kg. O manejo reprodutivo das novilhas começa quando estas atingem 14 ou 15 meses de idade e um peso de 350 a 370 kg. A produção de novilhas deve ser suficiente para substituir as vacas descartadas anualmente (25 a (...) 35%), e para contribuir com o crescimento do rebanho. Espera-se que em um gado leiteiro deva haver uma população de animais de reposição, desde um dia de vida até à fase de novilha ao parto, correspondendo pelo menos a 70 % do total das vacas (figura 1). -/- Figura 1: A meta do programa de produção de substitutos ou fêmeas de reposição consiste em uma novilha que chegue ao seu primeiro parto aos 24 ou 25 meses de idade, entre um peso de 550 a 580 kg. Elaborado pelo autor. -/- A produção de novilhas depende basicamente de três fatores: da fertilidade das vacas, ou seja, do número de bezerras nascidas anualmente; da mortalidade durante a criação e desenvolvimento; e da eficiência reprodutiva das novilhas. O manejo reprodutivo moderno das novilhas é orientado para a utilização da inseminação artificial, seja em um estro natural ou sincronizado. As novilhas representam a população animal geneticamente mais avançada no rebanho, portanto, o mérito genético de suas crias obtidas por inseminação é maior do que o das crias das vacas adultas. Além disso, as crias das novilhas obtidas mediante a inseminação aceleram o avanço genético, uma vez que contribuem com uma proporção maior de substituições do rebanho em comparação com as crias das vacas de outras faixas etárias. Além disso, as novilhas são as fêmeas mais férteis do rebanho (porcentagem de concepção: 60 a 70% vs 30 a 40% em vacas), pelo que o custo do sêmen por gestação é menor em comparação com as vacas adultas, o que permite investir em melhores touros e em sêmen sexado. -/- 1. PUBERDADE -/- A puberdade é definida como a fase de desenvolvimento em que a fêmea apresenta o seu primeiro estro fértil. Regularmente as novilhas leiteiras, sob condições ótimas de manejo, chegam à puberdade entre 11 e 12 meses de idade, ou seja, antes de alavancar o peso recomendado para receber o primeiro serviço. Vale salientar que as novilhas podem ficar gestantes após a puberdade; no entanto, isto não é conveniente porque ainda não completou-se o seu desenvolvimento. Se ficarem gestantes nos primeiros ciclos estrais, as novilhas poderiam chegar ao parto com pouco desenvolvimento físico, o que provocaria distocias e baixa produção de leite (figura 2). A ativação do sistema neuroendócrino para que a bezerra atinja a puberdade é regulada principalmente pelo estado nutricional (condição corporal). A transição do anestro pré-puberal à ciclicidade puberal coincide com um aumento da condição corporal e das concentrações de insulina, IGF-I e leptina. Estes hormônios agem como sinais metabólicos no hipotálamo e hipófise que modificam a frequência de secreção das gonadotropinas, resultando na maturação folicular e ovulação. O atraso em relação à puberdade está diretamente relacionado com deficiências na alimentação; esta condição verifica-se em criações pouco tecnificadas, principalmente de pequenos e médios produtores. As novilhas que já atingiram o peso para receber o primeiro serviço e não apresentaram estro, devem ser examinadas por via retal para excluir possíveis anormalidades do desenvolvimento, tais como freemartinismo ou hipoplasia genital. -/- Figura 2: O fator mais importante que determina a puberdade é a nutrição. Bezerras bem alimentadas apresentam ciclos estrais aos 11 meses de idade e devem ser inseminadas aos 14 ou 15 meses de idade, com um peso de 350 a 370 kg. Acervo pessoal do autor. -/- 2. DETECÇÃO DE ESTRO E INSEMINAÇÃO ARTIFICIAL -/- A baixa eficiência na detecção de estros é o problema que mais afeta a eficiência reprodutiva das novilhas. De acordo com a duração do estro (8 a 18 horas), a observação das novilhas em períodos de 30 minutos durante a manhã e à tarde, permite detectar em estro até 70% das fêmeas, enquanto a observação contínua (24 horas) aumenta a eficiência na detecção até 95% (figuras 3 e 4). No manejo tradicional dos rebanhos leiteiros, as novilhas recebem pouca atenção por parte dos trabalhadores, o que resulta em baixa eficiência na detecção de estros (50 a 60%). Em diferença das vacas adultas em lactação, as novilhas estão menos expostas a fatores que diminuem a expressão do estro, portanto, com uma rotina de observação, de pelo menos duas horas na manhã (6h a 8h da manhã) e duas horas pela tarde até a noite (17h da tarde a 19h da noite), pode-se detectar até 90% das fêmeas no estro (figura 5). -/- Figura 3: O fator que mais influencia a idade ao primeiro parto é a baixa eficiência na detecção de estros, pelo que é recomendável a observação de estros com pessoal qualificado, em períodos de pelo menos duas horas pela manhã e duas à tarde. Acervo pessoal do autor. -/- Figura 4: Com a observação contínua é possível alcançar de 90 a 95% de eficiência na detecção de estros. Acervo pessoal do autor. -/- Figura 5: A inseminação deve ser realizada durante o período de receptividade sexual. Com boa eficiência na detecção de estros, a inseminação pode ser praticada no programa AM-PM e PM-AM, ou em apenas um turno de inseminação pela manhã (10:00), com bons resultados. -/- 3. TAXA DE PRENHEZ -/- O melhor indicador de eficiência reprodutiva é a taxa de prenhez. Este indicador refere-se à proporção de animais gestantes do total elegível para inseminação, num período equivalente a um ciclo estral. Como já se descreveu no trabalho Fisiologia do Estro e do Serviço na Reprodução Bovina, este indicador considera a eficiência na detecção de estros e a porcentagem de concepção, e reflete com maior objetividade a eficácia do manejo reprodutivo. Este parâmetro pode ser melhorado através de um aumento da proporção de novilhas detectadas em estro, o que se obtém aumentando o tempo de observação e aplicando técnicas de sincronização do estro (figura 6). -/- 4. INSEMINAÇÃO DE NOVILHAS COM SÊMEN SEXADO -/- A utilização de sêmen sexado é uma boa opção para a produção de novilhas de reposição. Com a nova tecnologia disponível para a separação de espermatozoides com o cromossomo x, é possível alcançar até 90% de crias fêmeas; no entanto, o processo de separação de espermatozoides tem baixa eficiência, o que limita o número de espermatozoides por palheta. As palhetas de inseminação com sêmen sexado contém de dois a três milhões de espermatozoides (doses de sêmen não sexado têm de 20 a 30 milhões). De acordo com os dados de fertilidade de gados comerciais, as novilhas inseminadas com sêmen sexado mostram de 10 a 20% menor concepção que novilhas inseminadas com sêmen não sexado, o que desencoraja o seu uso. Causas de baixa fertilidade não são conhecidas, no entanto, estão associadas com a menor concentração espermática e com alguns danos nos espermatozoides provocados pelo processo de separação. No entanto, o uso de sêmen sexado é uma opção viável para aumentar a produção de novilhas no rebanho, e com o melhoramento dos processos de separação espermática em pouco tempo se converterá em uma prática de rotina nos estábulos (figura 7). -/- Figura 6: Uma técnica que aumenta a eficiência na detecção dos estros consiste em pintar a região da grupa. Quando esta pintura desaparece ou se nota que as novilhas estão "talhadas", devem ser apalpadas via retal para determinar se existem sinais genitais de estro. Acervo pessoal do autor. -/- Figura 7: As novilhas são as fêmeas mais férteis do rebanho, por isso o custo do sêmen por gestação é menor em comparação com as vacas adultas, o que permite investir em melhores touros e em sêmen sexado. Acervo pessoal do autor. 5. MONTA DIRIGIDA -/- A monta dirigida ou direta é uma opção prática e eficaz para emprenhar as novilhas. Neste sistema se introduz um touro com um grupo de novilhas, para que ele se encarregue de encontrar as fêmeas em estro e proceder a monta. Em rebanhos comerciais, o ideal é a utilização de um touro para 25 fêmeas. No entanto, com este manejo perde-se a oportunidade de utilizar a inseminação artificial e, com isso, a possibilidade de melhoria genética. -/- 6. PROGRAMAS DE SINCRONIZAÇÃO DE ESTROS -/- Os tratamentos para sincronizar o estro das novilhas possuem os mesmos fundamentos que os utilizados nas vacas. -/- 6.1 Prostaglandina F2a -/- A PGF2α é utilizada para a sincronização de estros em grupos de novilhas, e também é utilizada para a indução do estro individualmente, nas fêmeas que são examinadas por via retal e têm um corpo lúteo. A resposta dos animais tratados é variável; em novilhas pode-se alcançar até 95% de animais em estro. O tempo de manifestação do estro após a injeção é de 48 a 120 horas. -/- 6.1.1 Dupla injeção de PGF2a -/- Além da sincronização dos animais selecionados pela presença de um corpo lúteo diagnosticado por palpação retal, existem dois programas que não incluem a palpação retal. Por exemplo, na segunda-feira, ou no dia preferido, injeta-se PGF2α em todas as novilhas que se deseja inseminar. Cerca de 50% das novilhas manifestarão estro nas próximas 48 a 120 horas. As fêmeas que não mostrarem estro receberão uma segunda injeção na segunda-feira seguinte (intervalo de sete dias). As que apresentaram estro com a primeira injeção teriam um corpo lúteo nesse momento, enquanto as que não o manifestaram estavam em estro ou em metaestro; assim, ao repetir o tratamento sete dias depois, estas últimas novilhas teriam um corpo lúteo e responderiam à PGF2α (figura 8). No outro programa, é administrada duas doses de PGF2α com 11 dias de separação/intervalo. As novilhas podem ser inseminadas no estro observado, após qualquer uma das duas injeções. Este programa oferece uma boa sincroniza- ção após a segunda injeção e é o programa de escolha na sincronização das novilhas receptoras de embriões (figura 9). -/- Figura 8: Sincronização do estro com dupla injeção de PGF2a com 7 dias de diferença/intervalo. Elaborado pelo autor. -/- Figura 9: Sincronização do estro com dupla injeção de PGF2a com 11 dias de diferença/intervalo. Elaborado pelo autor. -/- 6.2 Progestágenos -/- Existe um tratamento que consiste na inserção, na parte externa da orelha, de um implante que contém norgestomet, que permanece na região auricular por nove dias. Além disso, o tratamento é complementado com a injeção intramuscular de valerato de estradiol e norgestomet, no momento da colocação do implante. O tempo de apresentação do estro a partir da remoção do implante é de 48 a 72 horas e a proporção de animais em estro muitas vezes se torna maior do que 80%. Outro tratamento é baseado na inserção intravaginal de dispositivos de liberação de progesterona. O dispositivo pode ser utilizado durante 12 dias ou o período de exposição pode ser encurtado, desde que seja acompanhado da injeção de uma dose luteolítica de PGF2α, um dia antes ou no momento da remoção do dispositivo. A fertilidade global conseguida após o serviço no estro sincronizado é similar à obtida no estro natural; porém, algumas novilhas são menos férteis, o que está associado com alterações no desenvolvimento folicular e alterações na relação temporal entre o estro e a ovulação. Observou-se que o tratamento com implantes de norgestomet combinados com a injeção de valerato de estradiol pode induzir comportamento estral em animais que não estão ciclando normalmente. Isso ocorre porque os níveis de estradiol, administrados no primeiro dia, persistem até o momento da remoção do implante. Assim, ao remover a fonte do progestágeno e ao haver concentrações altas de estradiol se desencadeia o estro, o qual em novilhas anéstricas não é acompanhado de ovulação, enquanto que em novilhas ciclando se altera a relação temporal entre o estro, pico pré-ovulatório de LH e ovulação. Bons resultados são alcançados quando o valerato de estradiol não é administrado e é substituído por uma injeção de PGF2α no momento da remoção do implante. Outro fator que tem sido associado com baixa fertilidade é o dia do ciclo em que o tratamento começa. Observou-se que quando coincide com a presença de um corpo lúteo (diestro), a porcentagem de concepção é maior do que quando não há um corpo lúteo (proestro). Isto ocorre porque a concentração sérica do progestágeno, por si só, não é capaz de suprimir a secreção pulsátil de LH, o que faz com que o folículo dominante presente no momento de iniciar o tratamento não sofra atresia e persista até o dia da retirada do progestágeno, convertendo-se no folículo ovulatório. Com isso, o folículo já envelheceu e o ovócito já sofreu alterações que reduzem o seu potencial para desenvolver um embrião viável. Quando o tratamento coincide com a presença de um corpo lúteo, a secreção de LH é efetivamente suprimida devido ao efeito aditivo da progesterona secretada pelo corpo lúteo e do progestágeno exógeno, inserido na vaca, o que provoca a reposição folicular. Em condições de campo, a seleção das vacas pela presença de um corpo lúteo antes de iniciar o tratamento com progestágenos é impraticável, uma vez que não é possível visualizá-lo, além disso essa prática/seleção não faria sentido, já que seria mais fácil tratar estes animais com dose ou doses de PGF2α. Atualmente existem tratamentos para eliminar folículos dominantes e promover uma nova onda folicular. -/- 6.3 Progestágenos orais -/- O acetato de melengestrol (MGA) é um progestágeno administrado por via oral. Em fêmeas bovinas é utilizado para melhorar a eficiência alimentar nos currais de engorda, o que se consegue através da inibição da apresentação do estro. Como todos os progestágenos, o MGA inibe a secreção de LH, eliminando assim a maturação do folículo e a ovulação. Após a remoção do MGA, o folículo dominante termina o seu desenvolvimento e as fêmeas apresentam estro em forma sincronizada. A dose de MGA por novilha é de 0,5 a 1 mg por dia, em tratamentos que variam de 9 a 14 dias. A apresentação comercial de MGA contém 0,22 mg do hormônio por 1 g do produto. O MGA pode ser facilmente misturado com qualquer concentrado ou grão moído. Após o último dia de tratamento, o estro se apresenta de dois a seis dias. O intervalo de remoção do MGA ao estro é mais longo quando comparado com outros progestágenos. Isto deve-se ao tempo de remoção do MGA, uma vez que enquanto um implante ou dispositivo intravaginal é removido abruptamente, o MGA pode continuar a ser absorvido enquanto é removido do trato gastrointestinal. Com tratamentos de 14 dias podem-se obter porcentagens de concepção menores em comparação com o estro natural, o que se deve em grande parte à ovulação de folículos persistentes. Um tratamento eficaz, que também melhora a fertilidade, consiste na administração de MGA durante 14 dias, seguido de uma injeção de PGF2α 15 ou 17 dias após a remoção do progestágeno. Com este programa, uma alta proporção de fêmeas teriam um corpo lúteo no momento da injeção da PGF2α e apresentariam estro com boa sincronização. Outro tratamento eficaz consiste na administração do MGA durante nove dias, mais uma dose de PGF2α ao nono dia; com este programa também se obtêm bons resultados em sincronização do estro e fertilidade. Este tratamento foi avaliado com novilhas holandesas e a porcentagem de fêmeas sincronizadas é elevada (95%). A porcentagem de concepção é semelhante à obtida no estro natural. Estes resultados são comparáveis aos obtidos com outros programas, como implantes de norgestomet ou dispositivos intravaginais de liberação de progesterona, mas com um custo significativamente menor (figura 10). -/- 6.4 Sincronização da ovulação e inseminação em tempo fixo -/- Em contraste com o observado em vacas em lactação, a resposta das novilhas aos programas de sincronização da ovulação e inseminação a tempo fixo é deficiente, o que se reflete em porcentagens de concepção de 20 a 35% menores que as novilhas inseminadas no estro natural. A causa desta resposta está relacionada com diferenças no desenvolvimento folicular; assim, nas novilhas o tempo de desenvolvimento do folículo dominante é mais rápido e o tempo de domínio é mais curto do que nas vacas em lactação. Desta forma, o folículo da onda folicular sincronizada com a injeção de GnRH sofre atresia antes da injeção de PGF2α, de tal forma que quando se induz a ovulação com a segunda injeção de GnRH, as novilhas têm folículos em diferentes estádios de desenvolvimento, o que provoca assincronia entre a ovulação e a inseminação artificial. -/- Figura 10: Programa de sincronização do estro com Acetato de Melengestrol (MGA). Elaborado pelo autor. -/- 7. MANEJO DO ANESTRO -/- Uma vez que as novilhas atingem a puberdade, apresentam ciclos estrais em intervalos de 21 dias que só são interrompidos pela gestação ou por alguma patologia. O anestro patológico é raro em novilhas; no entanto, surgem casos de piometra e cistos luteinizados, que são tratados com uma dose de PGF2α. Também se observam anormalidades de desenvolvimen- to, tais como freemartinismo e hipoplasia genital, patologias que não têm tratamento; somente 8% das novilhas freemartin são férteis. O anestro funcional (as novilhas manifestam estro, mas não são detectadas) é frequen- te e está diretamente relacionado com a eficiência na detecção de estros. As novilhas com idade e peso para se integrarem no programa reprodutivo e não apresentarem sinais de estro devem ser examinadas retalmente para diagnosticar a causa do anestro. Se, durante a palpação retal, as novilhas tiverem um corpo lúteo são tratadas nesse momento com PGF2α, os animais sem corpo lúteo podem receber uma injeção de PGF2α, sete dias depois. Este programa sincroniza o estro e aumenta a probabilidade de o detectar (figura 11). -/- Figura 11: As novilhas com idade e peso para se integrarem no programa reprodutivo e não mostrarem sinais de estro devem ser verificadas via retal para diagnosticar a causa do anestro. Arquivo pessoal do autor. -/- 8. MANEJO DA NOVILHA INFÉRTIL -/- A fertilidade das vacas leiteiras diminuiu nos últimos 30 anos, enquanto a fertilidade das novilhas não se alterou; após a primeira inseminação, entre 60 e 70% das novilhas emprenham. O objetivo do programa reprodutivo é conseguir que 90% das novilhas gestem nos primeiros três serviços. Desta forma, esta proporção de animais daria à luz antes dos 25 meses de idade. É comum que 10% das novilhas se transformem em animais repetidores, ou seja, novilhas com mais de três serviços inférteis. A causa da falha na concepção de novilhas deve-se principalmente à morte embrionária precoce. Uma causa importante da falha na concepção das novilhas repetidoras são as patologias adquiridas no aparelho reprodutivo; é comum encontrar aderências ovarianas e salpingite. Provavelmente, esses problemas são consequência de alguma infecção adquirida durante a criação. Diversos tratamentos hormonais têm sido testados para resolver o problema de infertilidade em novilhas repetidoras e os resultados obtidos ainda são deficientes. Como estes tratamentos não apresentam resultados consistentes, a melhor forma de mitigar o problema de infertilidade nas novilhas é melhorando as práticas de inseminação, ou seja, o momento da inseminação, o manejo do sêmen e a técnica de inseminação empregada. Além disso, a melhor técnica para aumentar a proporção de novilhas prenhes no rebanho é aumentar a eficiência da detecção de estros. -/- 9. RESUMO -/- As novilhas devem parir aos dois anos de idade (23 a 25 meses). O peso ao parto deve ser de 550 a 580 kg. O manejo reprodutivo começa aos 14 ou 15 meses de idade, com um peso de 350 a 370 kg. As palhetas de sêmen sexado contêm de 2 a 3 milhões de espermatozoides. As doses de sêmen não sexado contêm de 20 a 30 milhões de espermatozoides. A porcentagem de concepção das novilhas inseminadas com sêmen sexado é 10 a 20% menor do que com sêmen não sexado. Com sêmen sexado se obtém entre 90 e 95% de fêmeas. A porcentagem de concepção com programas de IATF é de 20 a 35% menor que nas novilhas inseminadas no estro natural. Cerca de 90% das novilhas devem ficar prenhes nos primeiros três serviços. Devem ser produzidas novilhas para substituir as vacas que são descartadas anualmen- te (25 a 35%). Espera-se que um gado leiteiro tenha ao dispor uma população de animais de reposição, desde um dia de vida até a etapa de novilha ao parto, correspondente a, pelo menos, 70 % do total das vacas. -/- REFERÊNCIAS BIBLIOGRÁFICAS -/- AUAD, Alexander Machado et al. Manual de bovinocultura de leite. Brasília: LK Editora, 2010. BRICKELL, J. S.; MCGOWAN, M. M.; WATHES, D. C. Effect of management factors and blood metabolites during the rearing period on growth in dairy heifers on UK farms. Domestic animal endocrinology, v. 36, n. 2, p. 67-81, 2009. DE VRIES, A. et al. Exploring the impact of sexed semen on the structure of the dairy industry. Journal of Dairy Science, v. 91, n. 2, p. 847-856, 2008. Fertilidade em Vacas Leiteiras: Fisiologia e Manejo. Fisiologia do Estro e do Serviço na Reprodução Bovina. FERREIRA, A. M. Manejo reprodutivo de bovinos leiteiros: práticas corretas e incorretas, casos reais, perguntas e respostas. Edição do autor, Juiz de Fora, 2012. FERREIRA, A. de M. Reprodução da fêmea bovina: fisiologia aplicada e problemas mais comuns (causas e tratamentos). Juiz de Fora: Minas Gerais–Brasil, p. 422, 2010. GALINA, Carlos; VALENCIA, Javier. Reproducción de los animales domésticos. 2006. GONÇALVES, J. N. Manual do produtor de leite. Viçosa, MG: Aprenda Fácil, 2012. HEINRICHS, A. J. Raising dairy replacements to meet the needs of the 21st century. Journal of dairy science, v. 76, n. 10, p. 3179-3187, 1993. HOFFMAN, P. C. Optimum body size of Holstein replacement heifers. Journal of Animal Science, v. 75, n. 3, p. 836-845, 1997. NEIVA, R. S. Criação eficiente de bezerros e novilhas. Lavras: Autor, 2013. NEIVA, Rogério Santoro. Produção de bovinos leiteiros. Lavras: UFLA, 1998. PEREIRA, E. S. et al. Novilhas leiteiras. Graphiti Gráfica e Editora LTDA, Fortaleza, Ceará, 2010. CARVALHO, B. C. Manejo reprodutivo de novilhas leiteiras. In. SENAR. Curso de reprodução e genética em bovinocultura de leite. Coronel Pacheco: Senar, 2021. YOUNGQUIST, Robert S.; THRELFALL, W. R. Large animal theriogenology. 2007. (shrink)

Aristotle says that ὑπαρχειν has as many senses as ‘to be true’ (PrA. , A, 36, 48b2-9) and as many ways as there are different categories. (PrA., A, 37, 49a6-9) This may mean that for every ‘is’ there is a ὑπαρχειν. Τhe reason is that Aristotle uses ὑπαρχειν in converse direction of ‘is’. The equal statement of ‘A is B’ with ὑπαρχειν is ‘B ὑπαρχει to A.’ Allen Bāck points to the difference between the use of the verb with dative (...) case and its use with a subject alone in Greek language. When it is used with the dative, it retains its basic meaning, that is, ‘be already present’ or ‘exist really.’ ‘So to say that P belongs to S is to say that P exists in S, or, if you like, that P has its being in S.’ He believes that Aristotle uses this construction to insist that primary substances alone are the fundamental being and all other things only are ‘in’ substances. Thus, when the verb is used with the dative, it expresses dependent substance relation. But when it is used with a subject alone, e.g. in ‘S ὑπάρχει,’ it expresses that the subject really exists. (OI., 17a24 and 17b2) Thus, while it is the subject which is said to be the predicate, it is the predicate which ὑπάρχει to the subject. The formula of ‘τὸ Α ὑπάρχει τῷ Β’ is equivalent to ‘τὸ Β ἐστι Α.’ He uses the word for the predication of a category on substance (e.g. Met., α, 993b24-25; Met., Z, 1029a15-16; Cat., 5, 3b24-25), the predication of secondary substance on primary substance (e.g. Met., Z, 1038b21-23; Cat., 5, 2a14-19), the predication of primary substance on nothing else but itself (e.g. Met., Z, 1040b23-24), the belonging of a verb to the subject, the belonging of axioms to a single science (Met., 1005a22-23) , the belonging of PNC to all things that are (Met., IV, 3) , in the sense of really existing (Cael. 297b22, Met., 1041b4. Cf. B503, 125-126) or merely in the sense of the predication of a predicate on a subject (e.g. OI., I, 5, 17a22-24) and especially and much more repeatedly than anywhere else in his discussion of syllogism. (e.g. PrA., A, 36, 48a40-b2; PrA., B, 22, 67b28-30; PrA., A, 24a26-28) It is also used in some related senses like mere belonging (e.g. Met., A, 989a10-14; K, 1060a9-10) or to be there. (So., B, 5, 417b23-26) Some of its derived forms are also used by Aristotle. For example, ἐνυπαρχον in the sense of the thing that is ‘in’ something; (e.g. Met., A, 991a13-16; Met., Z, 1038b29-33 and 1039a3-5) ὑπερέχον in the sense of that which contains and ὑπερεχόμενον in the sense of that which is contained in something else. (e.g. Met., Δ, 1020b26-28) In a sense, the extent of the application of ὑπαρχειν is wider than ‘is’ since it is not restricted to the nominative form in which ‘is’ is used but is applicable to other cases as well: ‘For ‘That does not belong to this’ does not always mean that ‘This is not that’ but sometimes that ‘this is not of that’ or ‘for that.’ (PsA., A, 36, 48b28-33) Allen Bāck (B503, 124) points that in the Prior Analytics Aristotle uses ‘ὑπάρχει τῷ’ and ‘κατηγορεῖσθαι κατά’ interchangeably. (e.g. at 25b37-26a4) Referring to its converse construction in respect of μετέχει (if A belongs to B, then B participates in A) as a probable reason that it may have Platonist foundations. But the question is: why does Aristotle uses this construction (B belongs to A) instead of simply saying A is B? Alexander of Aphrodisias (Apr 54.21-29) wonders why Aristotle had to adhere to such artificial language, entirely unnatural for ordinary speakers of Greek. As Jonathan Barnes points out, all the three formulas of ‘τὸ Α ὑπάρχει τῷ Β,’ ‘τὸ Α κατηγορεῖται κατὰ τοῦ Β’ and ‘τὸ Α λέγεται κατὰ τοῦ Β’ are artificial in the sense that no Greek who wanted to say that pleasure was good would normally have expressed himself by way of any of them.’ Bāck thinks Aristotle may have used it ‘to stress the primacy of primary substances as the ultimate subjects.’ He also mentions the probability that it may be to emphasize that the terms are being coupled in predication without any existence condition, a suggestion he is not himself inclined with. Robin Smith notes for Aristotle that ‘belonging to’ construction is wider than ‘predicated of’ construction because it can be used for cases that cannot easily be treated as categorical sentences. While predication is restricted to cases in which the subject term is in the nominative case, belonging can indicate, as he quotes Mignucci (480-481), ‘any possible grammatical construction for a predicative relation’ . (shrink)

How a group G can know that p has been the subject of much investigation in social epistemology in recent years. This paper clarifies and defends a form of non-supervenient, non-summative group knowledge: G can know that p even if none of the members of G knows that p, and whether or not G knows that p does not locally supervene on the mental states of the members of G. Instead, we argue that what is central to G knowing that (...) p is whether G has an epistemic structure that is functioning appropriately in accord with the action-related purposes of the group, and this structure may include non-agential elements such as devices that retain or process information. We argue that recent objections to non-summative group knowledge given by Jennifer Lackey do not in fact succeed in undermining the view, but do help to clarify the nature of non-summative group knowledge. The main upshot of our response to Lackey’s objections is that groups put their knowledge into action in ways that often differ from how individuals do so, and social epistemologists should be careful to notice these differences, especially insofar as groups often structure themselves by employing various epistemically-relevant devices. (shrink)

We outline a framework of multilevel neurocognitive mechanisms that incorporates representation and computation. We argue that paradigmatic explanations in cognitive neuroscience fit this framework and thus that cognitive neuroscience constitutes a revolutionary break from traditional cognitive science. Whereas traditional cognitive scientific explanations were supposed to be distinct and autonomous from mechanistic explanations, neurocognitive explanations aim to be mechanistic through and through. Neurocognitive explanations aim to integrate computational and representational functions and structures across multiple levels of organization in order to explain (...) cognition. To a large extent, practicing cognitive neuroscientists have already accepted this shift, but philosophical theory has not fully acknowledged and appreciated its significance. As a result, the explanatory framework underlying cognitive neuroscience has remained largely implicit. We explicate this framework and demonstrate its contrast with previous approaches. (shrink)

Each of the degenerating constitutions in Book VIII of Plato's Republic is the result of the disappearance of one of the four cardinal virtues. The failure of wisdom creates a timocracy; the failure of courage, an oligarchy; the failure of moderation, a democracy; the failure of justice, a tyranny. The degeneration shows that the disunited virtues are imperfect, though they have some power to stave off vice. Thus Book VIII implies a unity of the virtues thesis according to which perfect (...) virtues can only exist in a united state, but imperfect simulacra of virtue can exist in a disunited state. -/- Published 2011 in Apeiron: A Journal for Ancient Philosophy and Science. (Please note that the pagination in the uploaded document is not the same as the pagination in the published edition.). (shrink)

Monoclonal antibodies are essential biomedical research and clinical reagents that are produced by companies and research laboratories. The NIAID ImmPort (Immunology Database and Analysis Portal) resource provides a long-term, sustainable data warehouse for immunological data generated by NIAID, DAIT and DMID funded investigators for data archiving and re-use. A variety of immunological data is generated using techniques that rely upon monoclonal antibody reagents, including flow cytometry, immunofluorescence, and ELISA. In order to facilitate querying, integration, and reuse of data, standardized terminology (...) for describing monoclonal antibody reagents and their targets needs to be used for annotating data submitted to ImmPort. (shrink)

Augustine′s conversion to Christianity in A.D. 386 is a pivotal moment not only in his own life, but in Christian and world history, for the theology of Augustine set the course of theological and cultural development in the western Christian church. But to what exactly was Augustine converted? Scholars have long debated whether he really converted to Christianity in 386, whether he was a Platonist, and, if he adhered to both Platonism and Christianity, which dominated his thought. The debate of (...) the last thirteen decades spans an immense body of literature in multiple languages. In this literature, four major views on Augustine′s conversion may be discerned. The first view is associated with Gaston Boissier and Adolph von Harnack, and was famously championed by Prosper Alfaric: that Augustine in 386 converted to neo-Platonism but not to Christianity. Second, there is the view recently promoted by Catherine Conybeare: that Augustine in 386 converted to Christianity and rejected neo-Platonism. Third, there is the view that he converted to Christianity and was also a neo-Platonist; the most famous adherents of this view are Robert J. O′Connell and Pierre Courcelle. Finally, there is the view recently promoted by Carol Harrison: that Augustine committed to Christianity in 386, yet did not utterly reject neo-Platonism; rather, he aimed to develop a Christian faith that was informed by neo-Platonic insight. In this article, I first explain and distinguish these four general views, and then I explain why I prefer the fourth view. -/- More Info: This is the pre-peer reviewed version of Boone, Mark, "The Role of Platonism in Augustine's 386 Conversion to Christianity," Religion Compass 9.5 (May 2015), 151-61. This article has been published in final form at http://onlinelibrary.wiley.com/doi/10.1111/rec3.12149/abstract. (shrink)

Alvin Plantinga’s Warrant and Proper Function gives two major definitions of warrant. One states that reliable cognitive faculties aimed at true belief and functioning properly in the right environment are necessary and sufficient for warrant; the other definition only states that they are necessary. The latter definition is the more important one. There are different kinds of knowledge, and justification is necessary for some beliefs to be warranted. Even a belief warranted by proper function can receive a higher degree of (...) warrant by justification. This implies that natural theology has a useful role within the contours of a Plantingian epistemology. (Please note that the pagination here does not match the pagination in the published edition.). (shrink)

THIS IS A PRE-PUBLICATION VERSION OF THE PAPER. The New Testament speaks of our having faith rather than sight. This distinction is not made to distinguish faith from knowledge. Rather, it is to distinguish one kind of knowledge from another. We may know by trust in reliable authority; this knowledge is necessarily secondhand, but it is knowledge all the same. This, I argue, is the New Testament idea of faith. Another way of knowing is firsthand. Sight in the New Testament, (...) I argue, is a metonym for firsthand knowledge. In this article I consider the meaning of faith and sight in the relevant New Testament passages, with an extended exegesis of 2 Cor. 5:7 and Heb. 11:1. (shrink)

Augustine and William James both argue that religious faith can be both practical and rational even in the absence of knowledge. Augustine argues that religious faith is trust and that trust is a normal, proper, and even necessary way of believing. Beginning with faith, we then work towards knowledge by means of philosophical contemplation. James’ “The Will to Believe” makes pragmatic arguments for the rationality of faith. Although we do not know (yet) whether God exists, faith is a choice between (...) the risk of believing something false and the risk of not believing something true, and in the absence of convincing evidence we may decide for ourselves which risk we prefer. We may be able to experience God in the future and thereby gain knowledge, yet this may be contingent on our willingness to believe. There are key differences, however. Augustine is a Christian with a neo-Platonic bent, James an empiricist defending the religion of your choice. These differences may be less significant than they first appear. After explaining Augustine and then James I draw out the major points of comparison and contrast and suggest a few reasons their insights might be at least partially synthesized. -/- This is the accepted version of the following article: Mark J. Boone, “Augustine and William James on the Rationality of Faith,” The Heythrop Journal (online edition December 2018), which has been published in final form at [See First URL]. This article may be used for non-commercial purposes in accordance with the Wiley Self-Archiving Policy [See Second URL]. (shrink)

The Cell Ontology (CL) is designed to provide a standardized representation of cell types for data annotation. Currently, the CL employs multiple is_a relations, defining cell types in terms of histological, functional, and lineage properties, and the majority of definitions are written with sufficient generality to hold across multiple species. This approach limits the CL’s utility for cross-species data integration. To address this problem, we developed a method for the ontological representation of cells and applied this method to develop a (...) dendritic cell ontology (DC-CL). DC-CL subtypes are delineated on the basis of surface protein expression, systematically including both species-general and species-specific types and optimizing DC-CL for the analysis of flow cytometry data. This approach brings benefits in the form of increased accuracy, support for reasoning, and interoperability with other ontology resources. 104. Barry Smith, “Toward a Realistic Science of Environments”, Ecological Psychology, 2009, 21 (2), April-June, 121-130. Abstract: The perceptual psychologist J. J. Gibson embraces a radically externalistic view of mind and action. We have, for Gibson, not a Cartesian mind or soul, with its interior theater of contents and the consequent problem of explaining how this mind or soul and its psychological environment can succeed in grasping physical objects external to itself. Rather, we have a perceiving, acting organism, whose perceptions and actions are always already tuned to the parts and moments, the things and surfaces, of its external environment. We describe how on this basis Gibson sought to develop a realist science of environments which will be ‘consistent with physics, mechanics, optics, acoustics, and chemistry’. (shrink)

An increasing number of financial services (FS) companies are adopting solutions driven by artificial intelligence (AI) to gain operational efficiencies, derive strategic insights, and improve customer engagement. However, the rate of adoption has been low, in part due to the apprehension around its complexity and self-learning capability, which makes auditability a challenge in a highly regulated industry. There is limited literature on how FS companies can implement the governance and controls specific to AI-driven solutions. AI auditing cannot be performed in (...) a vacuum; the risks are not confined to the algorithm itself, but rather permeates the entire organization. Using the risk of unfairness as an example, this paper will introduce the overarching governance strategy and control framework to address the practical challenges in mitigating risks AI introduces. With regulatory implications and industry use cases, this framework will enable leaders to innovate with confidence. (shrink)

The comprehension of anaphoric relations may be guided not only by discourse, but also syntactic information. In the literature on online processing, however, the focus has been on audible pronouns and descriptions whose reference is resolved mainly on the former. This paper examines one relation that both lacks overt exponence, and relies almost exclusively on syntax for its resolution: adjunct control, or the dependency between the null subject of a non-finite adjunct and its antecedent in sentences such as Mickey talked (...) to Minnie before ___ eating. Using visual world eyetracking, we compare the time course of interpreting this null subject and overt pronouns (Mickey talked to Minnie before he ate). We show that when control structures are highly frequent, listeners are just as quick to resolve reference in either case. When control structures are less frequent, reference resolution based on structural information still occurs upon hearing the non-finite verb, but more slowly, especially when unaided by structural and referential predictions. This may be due to increased difficulty in recognizing that a referential dependency is necessary. These results indicate that in at least some contexts, referential expressions whose resolution depends on very different sources of information can be resolved approximately equally rapidly, and that the speed of interpretation is largely independent of whether or not the dependency is cued by an overt referring expression. (shrink)

NOW OPEN-ACCESS! In Reason, Authority, and the Healing of Desire in the Writings of Augustine, Mark Boone explains Augustine’s theology of desire in a cross-section of his writings. He shows that Augustine's writings consistently teach a Platonically informed, yet distinctively Christian, theology of desire.

In The Entangled Brain, Pessoa criticizes standard approaches in cognitive neuroscience in which the brain is seen as a functionally decomposable, modular system with causal operations built up hierarchically. Instead, he advocates for an emergentist perspective whereby dynamic brain networks are associated, not with traditional psychological categories, but with behavioral functions characterized in evolutionary terms. Here, we raise a number of concerns with such a radical approach. We ultimately believe that while much revision to cognitive neuroscience is welcome and needed, (...) Pessoa’s more radical proposals may be counterproductive. (shrink)

J. L. Mackie distinguished himself in twentieth-century philosophy by presenting an important objection to the traditional free will explanation for why God would allow evil: If evil is due to the free choice of creatures, why wouldn’t an omnipotent God simply create free creatures who would choose better? Alvin Plantinga, in turn, distinguished himself with his critique of Mackie. Plantinga’s main point is that Mackie made a mistake in assuming that it is within the power of omnipotence fully to create (...) just any possible world. However, Mackie made a second questionable assumption which Plantinga does not critique, and which I aim to clarify in this article. Mackie assumes that a God, as construed by classical theistic belief, who could create either of two people—one of whom would freely choose right and the other of whom would freely choose wrong—must create the one who would freely choose right. This assumption motivates Plantinga’s own account of trans-world depravity, which suggests that every free creature God might have created would have sinned had God created them. I consider Plantinga’s suggestion highly improbable. More importantly, under Mackie’s assumption, if there is at least one possible creature who would choose rightly, then there is no possibility of God ever allowing any other creature to sin, which would seem to be incompatible with their having any free will. -/- This version of the paper does have the same pagination as the published version. Permission has been granted from the Editor of Philosophia Christi to upload this contribution according to Philosophy Documentation Center terms of use. Learn more about the Journal by going to wwwepsociety. org/philchristi. (shrink)

Functional robustness refers to a system’s ability to maintain a function in the face of perturbations to the causal structures that support performance of that function. Modularity, a crucial element of standard methods of causal inference and difference-making accounts of causation, refers to the independent manipulability of causal relationships within a system. Functional robustness appears to be at odds with modularity. If a function is maintained despite manipulation of some causal structure that supports that function, then the relationship between that (...) structure and function fails to be manipulable independent of other causal relationships within the system. Contrary to this line of reasoning, I argue that functional robustness often attends feedback control, rather than failures of modularity. Feedback control poses its own challenges to causal explanation and inference, but those challenges do not undermine modularity—and indeed, modularity is crucial to grappling with them. (shrink)

This paper employs a case study from the history of neuroscience—brain reward function—to scrutinize the inductive argument for the so-called ‘Heuristic Identity Theory’ (HIT). The case fails to support HIT, illustrating why other case studies previously thought to provide empirical support for HIT also fold under scrutiny. After distinguishing two different ways of understanding the types of identity claims presupposed by HIT and considering other conceptual problems, we conclude that HIT is not an alternative to the traditional identity theory so (...) much as a relabeling of previously discussed strategies for mechanistic discovery. (shrink)

This paper is the submitted version. The published version of the paper is available using the DOI number 10.1111/heyj.14007.

American Pragmatist philosopher William James and subcontinent Islamic philosopher Allama Iqbal both believe that religious experiences are an important class of those experiences with which empiricism is concerned. They both explain and defend religious belief on empirical grounds and argue that the ultimate empirical justification of a religious belief must come by looking at its fruits. This is no accident, for James influenced Iqbal on this very point. -/- However, they diverge in some matters. James defends the right to diverse (...) religious belief and eventually articulates his own account based on religious experience—an account which is intentionally philosophical and not reliant on any religious authority. Iqbal, however, reconsiders and defends Islam understood along largely traditional lines. -/- I compare and contrast James’ and Iqbal’s religious epistemologies in order to understand both of them better and, hopefully, enrich contemporary reflection on faith and reason through a better awareness of the past dialogue on the subject. -/- This is the accepted version of the following article: “William James and Allama Iqbal on Empirical Faith;” The Heythrop Journal 61.5 (2020): 775-787, which has been published in final form at the URL provided. This article may be used for non-commercial purposes in accordance with the Wiley Self-Archiving Policy [see second URL]. (shrink)

The general idea of strong foundationalism is that knowledge has a foundation in well warranted beliefs which do not derive any warrant from other beliefs and that all our other beliefs depend on these foundational ones for their warrant. Although inerrancy posits Scripture as a solid foundation for theology, the idea that the doctrine of biblical inerrancy involves a strong foundationalist epistemology is deeply problematic. In fact, inerrancy does not require any particular view of the structure of knowledge, and notable (...) sources on inerrancy tout it in ways inconsistent with most forms of strong foundationalism. (shrink)

Although current educational priorities tend to avoid strong moral positions, one of the world's most venerable yet persistently influential moral traditions not only lays out a number of major moral principles but also incorporates them into its pedagogy. Confucius teaches us about the importance of seeking knowledge, learning how to learn, applying ancient wisdom to contemporary situations, valuing virtue over material gain, following the Golden Rule, and living by our principles. He also has ways of assessing his own students' progress (...) in these matters. Confucius' pedagogy is an interesting model to consider and contrast with contemporary models. This chapter introduces these principles and assessments from the Analects and draws out some comparisons to and contrasts with two alternative theories in western moral thought, Augustine and John Dewey. -/- The accepted version of the paper is included here. Pagination does not match the published version. (shrink)

THIS IS A PRE-PUBLICATION VERSION OF THE PAPER and does not have the same pagination as the published version. -/- It is sometimes said that religious belief and empiricism are different or even incompatible ways of believing. However, William James and notable twentieth-century philosophers representing Buddhism, Hinduism, Islam, Judaism, and Christianity have argued that there is a high degree of compatibility between religious faith and empiricism. Their analyses suggest that there are three characteristics of empiricism—that an empiricist bases his beliefs (...) on past experience, that he seeks to test his beliefs in future experience, and that he holds his beliefs with a degree of tentativeness in case future experience should uncover evidence against them. The epistemological insights of these philosophers, along with Augustine, show that Christian theology is consistent with empiricism. Indeed, reliance on faith fails to distinguish Christianity from science, and Christian theology is even to a significant extent both verifiable and falsifiable. (shrink)

In contrast to the successful previous year, 2020 turned out to be difficult, not only for the earth’s population due to COVID-19 but also for JDDM with an unusually small sixth volume. Looking back at these two very different years back-to-back led us to some reflection: As the COVID-19 pandemic forcefully illustrates, dynamic decision-making with all its complications and uncertainty is a topic of high relevance for modern societies.

Original meaning generally and authorial intent specifically are relevant to textual meaning. The author is not dead—a reasonable common-sense view in the absence of extremely good contrary evidence. If anyone should offer such evidence, they will not be able to take credit for it—at least not for writing it down! Accordingly, humanities teachers should train students to understand original meaning and authorial intent. This is one reason the humanities will continue to be relevant to other fields of study. Finally, this (...) is one reason to support a critical thinking pedagogy. I also connect these considerations to some of the major textual and cultural issues in South Asia. THE VERSION AVAILABLE HERE IS THE ACCEPTED MANUSCRIPT, NOT THE SAME AS THE FINAL PUBLISHED VERSION. (shrink)

Esta obra colectiva expone diversas concepciones teóricas, ontológicas, epistemológicas, axiológicas y prácticas sobre el origen, sentido, problemáticas, ventajas, detrimentos, alternativas y desafías de la filosofía de la innovación y su incidencia en la educación; reflexiona sobre las contribuciones de la tecnología y responde a interrogantes como: ¿Cuáles son los aporte de la tradición filosófica, del pensamiento ilustrado, de la postmodernidad y de la teoría crítica para la filosofía de la innovación educativa?; ¿Cuál es la función de la filosofía para la (...) comprensión de la innovación?; ¿Cómo se explica el progreso tecno-científico desde la epistemología contemporánea?; ¿Cuál es el componente pedagógico de la innovación?; ¿Cuáles son las aportaciones del Laudato Si para la innovación educativa?. Además, plantea la necesidad de repensar algunos aspectos relacionados con la educación, el Estado y la identidad latinoamericana para determinar las posibilidades, las limitaciones y los retos de la innovación, entendida como un fenómeno en permanente construcción. Este tomo se encuentra conformado por ocho capítulos en los que los autores formulan un conjunto de contribuciones para la generación de nuevas investigaciones. Además, evidencia a la innovación como un procesos que exige reformulaciones. La innovación sigue siendo una de las tareas pendientes de la filosofía. (shrink)