Most discussions of racial fetish center on the question of whether it is caused by negative racial stereotypes. In this paper I adopt a different strategy, one that begins with the experiences of those targeted by racial fetish rather than those who possess it; that is, I shift focus away from the origins of racial fetishes to their effects as a social phenomenon in a racially stratified world. I examine the case of preferences for Asian women, also known as ‘yellow (...) fever’, to argue against the claim that racial fetishes are unobjectionable if they are merely based on personal or aesthetic preference rather than racial stereotypes. I contend that even if this were so, yellow fever would still be morally objectionable because of the disproportionate psychological burdens it places on Asian and Asian-American women, along with the role it plays in a pernicious system of racial social meanings. (shrink)

This paper primarily investigates the following questions: The first question：What is the basic structure of consciousness? I proposed that objects moving at the speed of light form the fundamental structure of consciousness. The second question:How is the unified field of the conscious self formed? The study suggests that countless particles moving at the speed of light, through quantum entanglement, form the unified field of each individual's consciousness. Each individual's unified field consists of countless particles originating from a source, which can (...) be referred to as the "soul quantum." The third question:What is the mechanism underlying the formation of different forms of imagery (images, sounds, and bodily sensations)? The study posits that when the wave-particle duality of quantum mechanics collapses, it results in different forms of imagery. (shrink)

Statistics play a critical role in biological and clinical research. To promote logically consistent representation and classification of statistical entities, we have developed the Ontology of Biological and Clinical Statistics (OBCS). OBCS extends the Ontology of Biomedical Investigations (OBI), an OBO Foundry ontology supported by some 20 communities. Currently, OBCS contains 686 terms, including 381 classes imported from OBI and 147 classes specific to OBCS. The goal of this paper is to present OBCS for community critique and to describe a (...) number of use cases designed to illustrate its potential applications. The OBCS project and source code are available at http://obcs.googlecode.com. (shrink)

Statistics play a critical role in biological and clinical research. However, most reports of scientific results in the published literature make it difficult for the reader to reproduce the statistical analyses performed in achieving those results because they provide inadequate documentation of the statistical tests and algorithms applied. The Ontology of Biological and Clinical Statistics (OBCS) is put forward here as a step towards solving this problem. Terms in OBCS, including ‘data collection’, ‘data transformation in statistics’, ‘data visualization’, ‘statistical data (...) analysis’, and ‘drawing a conclusion based on data’, cover the major types of statistical processes used in basic biological research and clinical outcome studies. OBCS is aligned with the Basic Formal Ontology (BFO) and extends the Ontology of Biomedical Investigations (OBI), an OBO (Open Biological and Biomedical Ontologies) Foundry ontology supported by over 20 research communities. We discuss two examples illustrating how the ontology is being applied. In the first (biological) use case, we describe how OBCS was applied to represent the high throughput microarray data analysis of immunological transcriptional profiles in human subjects vaccinated with an influenza vaccine. In the second (clinical outcomes) use case, we applied OBCS to represent the processing of electronic health care data to determine the associations between hospital staffing levels and patient mortality. Our case studies were designed to show how OBCS can be used for the consistent representation of statistical analysis pipelines under two different research paradigms. By representing statistics-related terms and their relations in a rigorous fashion, OBCS facilitates standard data analysis and integration, and supports reproducible biological and clinical research. (shrink)

Prominent memeticists like Daniel Dennett and Susan Blackmore have made claims far more radical than those included in Dawkins’ original proposal, which provoked increasingly heated debates and arguments over the theoretical significance as well as limits or flaws of the entire memetic enterprise. In this paper, I examine closely some of the critical points taken by Kate Distin in her penetrating engagement with those radical claims, which include such ideas as the thought that we are meme machines as much as (...) gene machines, the thesis that there is no conscious self inside those machines, and the claim that a complex interplay of replicators and environment is all there is to life (Blackmore 1999: 241). It is hoped that a viable thesis concerning a deep-seated normativity emerges from my discussion. (shrink)

This article presents a robust defense of the concept of “datafied enhancement” as a subset of human enhancement. Firstly, the author notes that the widespread development of ICT and AI technologies has made it possible to collect and analyze human biometric data, thus integrating data into the concept of embodiment. Secondly, the author explores the cultural and intellectual history of datafied enhancement, highlighting the significant role data has played in human evolution. Thirdly, the author examines the functional classifications of datafied (...) enhancement, arguing that conversational, wearable, ingestible, and embeddable technological devices can enhance individuals’ physical, cognitive, emotional, and moral capacities by collecting body data. Fourthly, the author underscores the importance of distinguishing datafied enhancement from dataism to avoid misconceptions. Finally, the author addresses potential ethical issues, such as data exclusivity, the uncontrollable data self, and privacy invasion. By acknowledging these risks, datafied enhancement can be guided to become a technology that respects human dignity and promotes the common good. (shrink)

This paper addresses the issues related to designing and estimating the strength of solid-alloy elements in the deforming broaches of significant diameter (exceeding 150 mm) for the developed process of discrete broaching. The tool limit condition was assessed based on two strength criteria: the specific potential energy of shape change and the maximum tangent stresses. Numerical modeling using the finite element method has made it possible to derive the distribution of equivalent stresses in the tool elements and the contact stresses (...) at the surface of the contact between a solid-alloy insert and the body, which enabled the analysis of tool strength under loading. The simulation was performed under a single normal load, which ensured the versatility of the calculation for any contact pressure values. We have derived formulae to calculate the acceptable contact pressure depending on unit load. The effect of the insert protrusion height over the body on the strength of tool elements has been established. We have derived engineering dependences that determine the required magnitude of insert protrusion over the body depending on the ultimate load. An example of calculating the strength of a prefabricated deforming element in the machining of a sleeve made from gray modified cast iron of hardness HB230 has been considered. Our calculations have shown that the deforming element designed for the new technological process corresponds to the conditions of strength, provided the ratio h1/h=0.15 is maintained (where h1 is the insert height above the body, h is the insert height). The results obtained could be used in engineering calculations when designing the prefabricated tool for discrete deformation, as well as to assess the strength of prefabricated tools, such as cutters, core drills, reamers, when refining external loads. (shrink)

The main aim of this paper is to illustrate human–nature relations from a comparative study of the contexts of later Merleau-Ponty and the Zhuangzi. I argue that the Zhuangzi has its own phenomenology of the natural world, which is worth comparing to Merleau-Pontian later phenomenology. To compare the arguments on human–nature relations in the contexts of later Merleau-Ponty and the Zhuangzi in detail, first, I briefly compare the cultural philosophies of nature in ancient Greece and China and their possible influences (...) on our contemporary understanding of nature. Second, I compare the concept of “flesh” of Merleau-Ponty with the concept of “vital energy” in the Zhuangzi and point out the main roles of these concepts in their respective theories of the natural world. Third, I use the “reversibility thesis” created by Merleau-Ponty to analyze the ontological significance of illness in the arguments of Merleau-Ponty and the Zhuangzi. Fourth, inspired by Merleau-Pontian and Zhuangzian ideas about language and expression, I expound on a view of illness as a primordial language of nature and its possible role in mediating human–nature relations. Ultimately, I conclude that the comparative study of thoughts on human–nature relations in the literatures of later Merleau-Ponty and the Zhuangzi can help us reconsider and readjust our main attitudes toward nature, illness and nonhuman beings in the contemporary postpandemic era. (shrink)

The dissertation is a contrastive analysis. It deals with the acquisition of English relative clause (RC) by German and Turkish students(in Germany and Turkey) learning English as a second and third language and attending the 11th grades of a German school. The main question of the study is to find out whether the acquisition of English RCs is more difficult for German or for Turkish learners. The other study is the corpus analysis of the English relative clauses. For this research (...) I have chosen various school books from the fields such as History, Chemistry and Literature. The target is to find out how often the English relative clauses are used. They are from the same school level (11th grade) where I have applied the tests. I wanted to know which difficulties exists for the students. Moreover the frequency of English relative clauses in the school books has been given. (shrink)

Host-microbiome interactions (HMIs) are critical for the modulation of biological processes and are associated with several diseases, and extensive HMI studies have generated large amounts of data. We propose that the logical representation of the knowledge derived from these data and the standardized representation of experimental variables and processes can foster integration of data and reproducibility of experiments and thereby further HMI knowledge discovery. A community-based Ontology of Host-Microbiome Interactions (OHMI) was developed following the OBO Foundry principles. OHMI leverages established (...) ontologies to create logically structured representations of microbiomes, microbial taxonomy, host species, host anatomical entities, and HMIs under different conditions and associated study protocols and types of data analysis and experimental results. (shrink)

When a widely reused ontology appears in a new version which is not compatible with older versions, the ontologies reusing it need to be updated accordingly. Ontobull has been developed to automatically update ontologies with new term IRI(s) and associated metadata to take account of such version changes. To use the Ontobull web interface a user is required to (i) upload one or more ontology OWL source files; (ii) input an ontology term IRI mapping; and (where needed) (iii) provide update (...) settings for ontology headers and XML namespace IDs. Using this information, the backend Ontobull Java program automatically updates the OWL ontology files with desired term IRIs and ontology metadata. The Ontobull subprogram BFOConvert supports the conversion of an ontology that imports a previous version of BFO. A use case is provided to demonstrate the features of Ontobull and BFOConvert. (shrink)

Ordinary action explanation formulated as "I am doing A because I am doing B" is explanation of an action in terms of another action-in-progress. According to Michael Thompson, the explained action is a teleological part of the explaining complex action, which is composed of different parts. Thompson's analysis focuses on the part-whole relation between the explained action and the explaining action, thus ignores a possibility: these two actions can be two different parts of a complex action. I shall argue that (...) the interrelation between different parts of a complex action corresponds to a new kind of action explanation of the formulas: "I am doing A because I am doing B" and "I am doing B because I have done A", where A and B are two different parts of a complex action. This kind of action explanation is associated with the temporal schema of an action-type, for example, X: First, do A; second, do B; then, C; finally, D. This is an attempt to probe into the inner structure of complex action. (shrink)

The most important stage of the sound phenomenon for children covers the time that starts from the mother's womb and continues until the school period. A child starting school (6:5 or 7 years old) is just learning to write. However, he acquired the language/s/ almost entirely thanks to the sound in the mentioned period. In this respect, the processing of language and sound in the brain of newborn babies becomes important. The language acquisition level of newborns may vary in terms (...) of such reasons as genetics, ability, and frequency of exposure, environmental factors, and whether they are physically and mentally healthy or not. This study deals with the question of what kind of a connection is there between the phenomenon of sound, especially the sound of music, and the acquisition of two languages in early childhood. In short, the subjects of language acquisition and musical sound in early childhood have been investigated in the literature with a qualitative method. Another question is how do the two languages acquired in early childhood stay with each other in a developmental relation. In the study, it was understood that there is not a single result from the studies on children grown up monolingual or bilingual in early childhood. The opinion that the sooner one or two languages are learned in early childhood (usually by exposure to the sound) the better the acquisition would be is outweighed, though there are different opinions about the results of the scientists. In addition, since it was concluded that there is a developmentally parallel relationship between the sound of music and the acquisition of language by newborns, it means that ontology gives us the summary of phylogenesis. (shrink)

The concept of gender (male and female) is an issue that can be handled biologically, socially and individually. Whether the gender - based language production differences are linguistic, social hierarchy or culture has long been discussed and debated by different scientific circles. Studies on whether men and women produce different languages coincide with the 1970s, when the feminism movement emerged in the world. In the same period, sociolinguistic researches were carried out at scientific levels. These sociolinguistic studies are considered to (...) be the first important studies on malefemale language production differences. Looking at language and gender studies, it is seen that there is a general, intensified focus on two questions: First, do men and women use language differently (in different dimensions)? Secondly, is the language that describes the man and the language that describes the woman different from each other in written or oral modules in social life? An attempt was made to find an answer to the question “do men and women really speak differently” in this qualitative study, based on the literature. Although there are various studies on gender-based language use differences, it seems that this issue is open to discussion. It is possible to say that the difference in gender-based language use is not certain due to reasons such as the fact that most of the studies were conducted with small data and different methods, up-to-date data were not used, and most of the data were collected from the English language. (shrink)

Prepositions as function words and single monomorphemic words are the most basic words of the human language, especially in the context of maintaining daily life. They are probably the first lexes/words entered to the human’s linguistic repertoire, as their requirements in the language are so essential. Prepositions shows various relationships between lexes or phrases in sentences. Among these relationships time, points, position, direction and various degrees of mental or emotional attitudes seem to be significant. The purpose of the research is (...) try to reveal what kind of challenges English prepositions have for the learners and also to confirm if they are as difficult as some linguists have stated before. Another purpose is to find out which features are more difficult among all their entity properties. The results of this study disclose that English prepositions possess very complex structures, different meanings and an associating duty of various types of part of speeches. In particular, those that construct the phrasal verbs require great effort for learning due to the loss of the meaning (sometimes partially, sometimes completely) they undergo. It has been understood that their properties such as steadily changing meaning and function make them quite difficult elements for learners of English. (shrink)

Acronym is a very important word derivation mechanism usually applied to the new names of private or public institutions and they can be used to shorten the names of people, places, or institutions. This linguistic opportunity, which can be found in every language of the world, is quite useful in terms of its easiness and economic use of the languages. It provides the people ease of language use with reducing the length of some nouns and phrases and helping to memorize (...) them. It functions as phonemic and graphemic shortening. In Turkish, there are a great number of domestic acronyms (e.g. ÖSYM, PTT, and TBMM) and English/international ones as well (e.g. BBC, NATO, and NASA). The purpose of this study is to reveal if the Turkish speakers (L1) will prefer the articulation of English acronyms as in English or as in Turkish. A qualitative research method was preferred with using a quantitative data collection tool. 24 sentences, in each one was embedded an acronym, were prepared and given to 24 participants who were newly registered students (at the university). This study shows that these students pronounced nearly all of the acronyms as in English rather than Turkish. This is probably because they deem English more prestigious. The other reason might be that there is no consistency (or willingness) in terms of the utilisation of English acronyms among the public agencies alongside with the mass media and official institutions in Turkey. (shrink)

Social developments/events of three different periods (Elizabethan Period (1558-1603), Jacobean Period (1603-1625) and Caroline Period (1625-1649) might have had great impact on Ben Jonson’s writing the play Volpone. In this qualitative study (conducted with literature research on the topic), Volpone through which he best reflected his corrupted society at that time will be examined. The play will be analysed to illuminate the native features related to the market economy. The economic sight based on commodity has such a great power in (...) changing the characters of the people, losing their morals because of their greed towards the power and wealth during the mentioned period. Another point to be discussed is to reckon whether Ben Jonson as a Dramatist had contrary opinions against the developing capitalist world. In the study, it has been found that the play of Volpone (the fox) depicts one of the best evidence how the characters can be changed through materialism. As a main character, he is a wealthy Venetian nobleman and exceptionally cunning, who devises a plan (pretending to die) with the assistance of his henchman (Mosca/ fly) to exploit his relatives waiting to be an heir of him. The play shows how his relatives flatter him and give him the most expensive gifts. He deceives each of them at the end. The play draws attention to the materialistic power of the 16th century. (shrink)

In the globalizing world foreign language learning is becoming more and more important. This case leads to new developments in language learning research. The purpose of this study is to depict whether the second language learning would occur better in the childhood or later. In other words to investigate the question of in which period of bilingualism it will be better. In order to answer this question, important sources in the linguistic field, related to the topic, were highlighted. The important (...) researches and theories mentioned in the literature have been examined, evaluated, information about the first and second language learning has been given and the subject has been discussed from the scientific point of view. In this context, it has been understood that many reasons exist affecting the level of proficiency of preand post- 12 year's language learning (in mono-, bi-, tri-, quadra- or multi-, lingualism) such as age, brain function, individual differences, ambience differences; social, political, economic background and how to regard the language. The idea that bilingualism after the critical period (around the age of 12) could not be as that of the childhood has been gained weight, due to the system differences between two languages, especially the difficulties in intoning and pronouncing. (shrink)

It is known that Turkish, like all languages, has changed and is in a process of change. The direction of the change in question is both from verbal language to written language and from written language to verbal language. Changes are studied in linguistics by two different types of research approaches, namely diachronic and synchronic. This qualitative study using the quantitative data collection tool focused on the phenomenon of synchronic change. The aim of this descriptive study is to reveal to (...) what extend the reductions in verbal Turkish has reflected on written language. For this purpose, four words with adverbial functions (daha, beri, kadar ve kere), whose use in daily speech is gradually decreasing, from everyday language in standard Turkish of Turkey have been chosen, a " grammatical judgement test " has been prepared and applied to sample group that consists of 24 undergraduate students studying in Turkish Language and Literature department. As a result of the research, is has been determined that the functions of these words dropped in daily language use are provided with suffixes. It was observed that a significant part of the participants tended to accept the sentences whose words with adverbial were omitted. (shrink)

The purpose of this paper is to bring to the light what difficulties or burden the English Adverbial Clauses have for foreign language learners (FLLs) or second language learners (SLLs) In this context, the syntactic structure of such grammatical category has been examined. This has been done by examining the syntactic properties of adverbial clauses as grammatical unity by emphasising their structures. The most important books that are available in the English speaking world have been inquired. This corpus analysis has (...) depicted that steadily changing of some adverbial clauses as subordinates is a problem for the learners in sentence processing. The varieties of the construction have proved to be a burden for the foreign learners. Moreover, the study underlines that the adverbial constructions contradict with the typological word order (SVO) of English language i.e. the canonical word order of English is violated through these operations. Again the classifications, the reduction and the inversion of them are great challenges for the foreign learners. (shrink)

The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely defined meanings to describe all aspects of how investigations in the biological and medical domains are conducted. OBI re-uses ontologies that provide a representation of biomedical knowledge from the Open Biological and Biomedical Ontologies (OBO) project and adds the ability to describe how this knowledge was derived. We here describe the state of OBI and several applications that are using it, such as adding semantic expressivity to (...) existing databases, building data entry forms, and enabling interoperability between knowledge resources. OBI covers all phases of the investigation process, such as planning, execution and reporting. It represents information and material entities that participate in these processes, as well as roles and functions. Prior to OBI, it was not possible to use a single internally consistent resource that could be applied to multiple types of experiments for these applications. OBI has made this possible by creating terms for entities involved in biological and medical investigations and by importing parts of other biomedical ontologies such as GO, Chemical Entities of Biological Interest (ChEBI) and Phenotype Attribute and Trait Ontology (PATO) without altering their meaning. OBI is being used in a wide range of projects covering genomics, multi-omics, immunology, and catalogs of services. OBI has also spawned other ontologies (Information Artifact Ontology) and methods for importing parts of ontologies (Minimum information to reference an external ontology term (MIREOT)). The OBI project is an open cross-disciplinary collaborative effort, encompassing multiple research communities from around the globe. To date, OBI has created 2366 classes and 40 relations along with textual and formal definitions. The OBI Consortium maintains a web resource providing details on the people, policies, and issues being addressed in association with OBI. (shrink)

Shihab al-Din al-Suhrawardi was born around 1154, probably in northwestern Iran. Spurred by a dream in which Aristotle appeared to him, he rejected the Avicennan Peripatetic philosophy of his youth and undertook the task of reviving the philosophical tradition of the "Ancients." Suhruwardi's philosophy grants an epistemological role to immediate and atemporal intuition. It is explicitly anti-Peripatetic and is identified with the pre-Aristotelian sages, particularly Plato. The subject of his hikmat al-Ishraq --now available for the first time in English--is the (...) "science of lights," a science that Suhrawardi first learned through mystical exercises reinforced later by logical proofs and confirmed by what he saw as the parallel experiences of the Ancients. It was completed on 15 September 1186 and at sunset that evening, in the western sky, the sun, the moon, and the five visible planets came together in a magnificent conjunction in the constellation of Libra. The stars soon turned against Suhrawardi, however, who was reluctantly put to death by the son of Saladin, the sultan of Egypt, in 1191. (shrink)

In the contemporary free will debate between compatibilism — the thesis that free will is compatible with determinism, and incompatibilism — that free will is incompatible with determinism, many scholars are sympathetic to compatibilism, yet disagree in how the position is best characterized. As one of the most important branches of source compatibilism, reasons-responsive theories attempt to address an important issue, namely, what type of person can be regarded as moral agents. There are several controversial points within the theory. This (...) paper aims to show that reasons-responsive theories fail as a solution to the free will debate, to the extent that they remain silent on the issue of the nature of reasons. It is this silence and inadequacy that constitute a rebuttal to reasons-responsive theories. In what follows I will propose a dilemma to reasons-responsive theories: if moral reasons are objective in the sense that one could be wrong about them, it appears that one must be a moral expert to possess the so-called “reasons-reactivity”, a necessary condition for the possession of free will. This will later be shown to be deeply implausible. If moral reasons are instead subjective in the sense that whether one has a moral reason to do X crucially depends on his mental states, then reasons-responsiveness seems to have no connection with free will at all. In addition, there are independent grounds on which the subjective account of the nature of reason can be challenged. Therefore, no matter which road reasons-responsive theorists choose to go down, there are serious objections that cast doubt on their plausibility. At the end of the paper, I will touch on the question of why reasons-responsive theories are doomed to failure due to their lack of concern with the agent’s own psychology. (shrink)

The target of Second- Language Acquisition (SLA), emerged in the second half of the 20th century, was to be helpful in foreign- language education/ teaching. It denotes mostly the study of individuals (or sometimes groups) who are learning a language consequent to learning their first language when they are young children. At the same time, it signifies the process of learning a second language. The added language is named a second language, but it might indeed be the third, fourth or (...) more which is going to be acquired. The range of SLA comprises informal Second- Language Learning occurring in natural milieus, formal second- language learning occurring in classroom or the one that contains a combination of them both, that is, settings and conditions. The three main aspects for the study of SLA process are the linguistic, psychological and social aspects. The Monitor Theory/ Model postulated by Krashen in the 1970s is a psychological approach in nature. With its five hypotheses (The Acquisition– Learning Hypothesis, The Monitor Hypothesis, The Natural Order Hypothesis, The Input Hypothesis, and The Affective Filter Hypothesis), it tries to find answers to the problems of SLA, such as what does a second- language learner come to know, how the acquisition process takes place, and why some learners are more successful than others? The Monitor Theory (MT) received extensively many criticisms after its appearance and was rejected. Its teaching implications were also at the centre of criticisms. What place does MT occupy in SLA today? This study aims to try to find an answer. The other questions are: How important is the MT for SLA? What kind of criticisms are expressed against it? How fair is the criticism by McLaughlin (1978, 1987)? The working hypotheses of the present work are: The hypotheses developed by Krashen are not/ will not be rejected. Because science is still lying in the so- called agony phase, and cannot find any answers to all questions in psychology (e.g. how exactly is the processing of language; in particular and of mind in general). Moreover, the problems related to memory etc., the thoughts emanated from the MT can probably not be refuted. They have evolved so far and will be evolved further, perhaps with small differences. This research is completely based on the literature written since the time the theory was developed. In other words, it was carried out using a descriptive method without using a special data collection tool. The sources written on the subject were reviewed and an answer to the research questions was tried to be found. Even though the theory is expressed with different names and different meanings today, it has survived all the criticisms made, and it has been concluded that it still occupies an important place in the discipline of second- language acquisition (SLA) and foreign- language teaching. Again, the inquiries carried out since the 1970s delineate that the implications in favour of language education are not very different from those stated by Krashen (1982), which were the products of his opinions in that period. There are still basic consequences grounded on MT for language teaching today. (shrink)

Purpose. To determine the potential of deforming broaching for the improvement of efficiency of cutter chisels in the mining industry. Methodology. The study of the application of the technological process of deforming broaching was carried out based on the experimental research into conditions of assembly of press couplings corresponding to cutting rock-destroying tools, the working surface of which is reinforced with solid-alloy inserts. Findings. Based on the conducted research, a new process of assembling the crowns of cutter chisels with the (...) use of deforming broaching was developed. Originality. It was determined that the range of angles of inclination of generatrix of the working cone of the deforming element and the roll-treading lip of the insert, which are necessary for efficient machining and pressing in crowns of cutters, is 4–16°. It was proven that the “solid alloy-steel” press couplings for cutter chisels will have the maximum bearing capacity at total tension a/d0 ≤ 3 %. It was found that it is necessary to foresee the following distribution of tensions: to perform 2 % of deformation by preliminary deforming broaching, and 1 % ‒ by pressing in an insert Practical value. The use of deforming broaching makes it possible to increase the strength of fastening the inserts of cutter chisels by 2 times, to reduce specific consumption of the tool by 4.4 times, and to increase the average drilling rate by 4 times. (shrink)

Biological ontologies are used to organize, curate, and interpret the vast quantities of data arising from biological experiments. While this works well when using a single ontology, integrating multiple ontologies can be problematic, as they are developed independently, which can lead to incompatibilities. The Open Biological and Biomedical Ontologies Foundry was created to address this by facilitating the development, harmonization, application, and sharing of ontologies, guided by a set of overarching principles. One challenge in reaching these goals was that the (...) OBO principles were not originally encoded in a precise fashion, and interpretation was subjective. Here we show how we have addressed this by formally encoding the OBO principles as operational rules and implementing a suite of automated validation checks and a dashboard for objectively evaluating each ontology’s compliance with each principle. This entailed a substantial effort to curate metadata across all ontologies and to coordinate with individual stakeholders. We have applied these checks across the full OBO suite of ontologies, revealing areas where individual ontologies require changes to conform to our principles. Our work demonstrates how a sizable federated community can be organized and evaluated on objective criteria that help improve overall quality and interoperability, which is vital for the sustenance of the OBO project and towards the overall goals of making data FAIR. Competing Interest StatementThe authors have declared no competing interest. (shrink)

This paper is a study about Philadelphia’s comprehensive user engagement sites (CUESs) as the authors address and examine issues related to the upcoming implementation of a CUES while seeking solutions for its disputed questions and plans. Beginning with the federal drug schedules, the authors visit some of the medical and public health issues vis-à-vis safe injection facilities (SIFs). Insite, a successful Canadian SIF, has been thoroughly researched as it represents a paradigm for which a Philadelphia CUES can expand upon. Also, (...) the existing criticisms against SIFs are revisited while critically unpackaged and responded to in favor of the establishment. In the main section, the authors propose the layout and services of the upcoming CUES, much of which would be in congruent to Vancouver’s Insite. On the other hand, the CUES would be distinct from Insite, as the authors emphasize, in that it will offer an information center run by individuals in recovery and place additional emphasis on early education for young healthcare professionals by providing them a platform to work at the site. The paper will also briefly investigate the implementation of a CUES site under an ethical scope of the Harm Reduction Theory. Lastly, the authors recommend some strategic plans that the Philadelphia City government may consider employing at this crucial stage. (shrink)

The current COVID-19 pandemic and the previous SARS/MERS outbreaks of 2003 and 2012 have resulted in a series of major global public health crises. We argue that in the interest of developing effective and safe vaccines and drugs and to better understand coronaviruses and associated disease mechenisms it is necessary to integrate the large and exponentially growing body of heterogeneous coronavirus data. Ontologies play an important role in standard-based knowledge and data representation, integration, sharing, and analysis. Accordingly, we initiated the (...) development of the community-based Coronavirus Infectious Disease Ontology in early 2020. -/- As an Open Biomedical Ontology (OBO) library ontology, CIDO is open source and interoperable with other existing OBO ontologies. CIDO is aligned with the Basic Formal Ontology and Viral Infectious Disease Ontology. CIDO has imported terms from over 30 OBO ontologies. For example, CIDO imports all SARS-CoV-2 protein terms from the Protein Ontology, COVID-19-related phenotype terms from the Human Phenotype Ontology, and over 100 COVID-19 terms for vaccines (both authorized and in clinical trial) from the Vaccine Ontology. CIDO systematically represents variants of SARS-CoV-2 viruses and over 300 amino acid substitutions therein, along with over 300 diagnostic kits and methods. CIDO also describes hundreds of host-coronavirus protein-protein interactions (PPIs) and the drugs that target proteins in these PPIs. CIDO has been used to model COVID-19 related phenomena in areas such as epidemiology. The scope of CIDO was evaluated by visual analysis supported by a summarization network method. CIDO has been used in various applications such as term standardization, inference, natural language processing (NLP) and clinical data integration. We have applied the amino acid variant knowledge present in CIDO to analyze differences between SARS-CoV-2 Delta and Omicron variants. CIDO's integrative host-coronavirus PPIs and drug-target knowledge has also been used to support drug repurposing for COVID-19 treatment. -/- CIDO represents entities and relations in the domain of coronavirus diseases with a special focus on COVID-19. It supports shared knowledge representation, data and metadata standardization and integration, and has been used in a range of applications. (shrink)

A scarcity mindset is considered to impact consumer behaviors. Our research aimed to examine the moderating effect of the scarcity mindset on the relationship between mental accounting and hedonic (vs. utilitarian) consumption. We conducted an online experimental design (mental accounting: windfall gains vs. hard-earning gains; consumption: hedonic products vs. utilitarian products) and verified our hypotheses in two distinct samples: a student sample and an adult sample. Our results showed that consumers who received windfall gains tended to use it for hedonic (...) consumption rather than utilitarian consumption. Intriguingly, such an effect was insignificant under a high level of a scarcity mindset but significant under a low level of the scarcity mindset. Moreover, consumers who received hard-earning gains tended to spend the money on utilitarian (vs. hedonic) consumption. However, we did not detect the impact of the scarcity mindset on such effects. Our research suggested an asymmetric effect of the scarcity mindset on hedonic (vs. utilitarian) consumption under two different mental accounts. It highlights the important role of the scarcity mindset in consumer behaviors, which leaves avenues for future research to understand marketing promotion strategies for distinct products. (shrink)

The translational research community, in general, and the Clinical and Translational Science Awards (CTSA) community, in particular, share the vision of repurposing EHRs for research that will improve the quality of clinical practice. Many members of these communities are also aware that electronic health records (EHRs) suffer limitations of data becoming poorly structured, biased, and unusable out of original context. This creates obstacles to the continuity of care, utility, quality improvement, and translational research. Analogous limitations to sharing objective data in (...) other areas of the natural sciences have been successfully overcome by developing and using common ontologies. This White Paper presents the authors’ rationale for the use of ontologies with computable semantics for the improvement of clinical data quality and EHR usability formulated for researchers with a stake in clinical and translational science and who are advocates for the use of information technology in medicine but at the same time are concerned by current major shortfalls. This White Paper outlines pitfalls, opportunities, and solutions and recommends increased investment in research and development of ontologies with computable semantics for a new generation of EHRs. (shrink)

Introduction: The development of advanced sewage technologies empowers the industry to produce high-quality recycled water, which greatly influences human’s life and health. Thus, this study investigates the mechanism of individuals’ adoption of recycled water from the technology adoption perspective. -/- Methods: Employing the mixed method of structural equation modeling and artificial neural network analysis, we examined a research model developed from the extended Unified Theory of Acceptance and Use of Technology (UTAUT2) framework. To examine the research model, this study employs (...) a leading web-survey company (Sojump) to collect 308 valid samples from the residents in mainland China. -/- Results: The structural equation modeling results verified the associations between the six predictors (performance expectancy, effort expectancy, social influence, facilitating conditions, environmental motivation, and price value), individuals’ cognitive and emotional attitudes, and acceptance intention. The artificial neural network analysis validates and complements the structural equation modeling results by unveiling the importance rank of the significant determinants of the acceptance decisions. -/- Discussion: The study provides theoretical implications for recycled water research and useful insights for practitioners and policymakers to reduce the environmental hazards of water scarcity. (shrink)

¿Cuál debe ser la actitud de un pensamiento genuinamente postmoderno ante el fenómeno religioso? ¿Debe contribuir a desterrarlo de nuestras sociedades (en alianza con cierto racionalismo ilustrado que siempre miró con suspicacia cuanto no cabía dentro de sus estrechos criterios) o, por el contrario, debe colaborar en su emergente renacimiento (y aliarse, por tanto, con los diversos tradicionalismos que lo reivindican)? La filosofía de Gianni Vattimo constituye una respuesta a esta disyuntiva (típicamente moderna) desde una perspectiva que pretende distorsionar (verwinden) (...) tal dicotomía. La idea clave para ello es el concepto de secularización que, a la vez que reconoce nuestra dependencia, como occidentales, de un cierto discurso religioso, lo debilita con el fin de eliminar de él su violencia (pues, de modo circular, reconoce que dentro de él ya existía in nuce el proyecto de esta eliminación, el proyecto de la kénosis). El presente artículo analiza someramente estas ideas y traza algunas de sus conexiones (no siempre explicitadas por el propio Vattimo) con el pensamiento teológico más reciente, para después reseñar algunas de las consecuencias que han tenido en los debates filosóficos hispanos. (shrink)

Analysis in English of Annalisa D. Quagliata Blanco’s experimental feature film ¡Aoquic iez in Mexico! /¡Ya México no existirá más! (2024).

Spanish version of essay on the film ¡Aoquic iez in Mexico! / ¡Ya México no existirá más! (Annalisa D. Quagliata Blanco, 2024).

Enis Doko bu kitapta 1) ahlakın doğasından hareketle nesnel ahlaki olguların varlığına (ahlaki gerçekçilik), 2) ahlaki gerçekçilikten hareketle ahlaki olguların doğal olgular olamayacağına, 3) doğal olmayan ahlaki olguların varlığından hareketle de Tanrı'nın varlığına ulaşmaya çalışıyor. Göreceğimiz gibi bu üç adımın her biriyle ilgili ciddi sorunlar var.

Notwithstanding its value as the earliest extant New Persian treatment of the art of rhetoric, Rādūyānī’s Interpreter of Rhetoric (Tarjumān al-Balāgha) has yet to be read from the vantage point of comparative poetics. Composed in the Ferghana region of modern Central Asia between the end of the eleventh century and the beginning of the twelfth century, Rādūyānī’s vernacularization of classical Arabic norms inaugurated literary theory in the New Persian language. I argue here that Rādūyānī’s vernacularization is most consequential with respect (...) to its transformation of the classical Arabic tropes of metaphor (istiʿāra) and comparison (tashbīh) to suit the new exigencies of a New Persian literary culture. In reversing the relation between metaphor and comparison enshrined in Arabic aesthetics, Rādūyānī concretized the Persian contribution to the global study of literary form. -/- . (shrink)

History of science students will want to read this book. Professor Zuo animates the life, career, and thought of SHEN Gua in this delightful historical, biographical work. SHEN Gua embodied the classical spirit of the scholar-official during the Song dynasty. Shen is the author of Brush Talks from Dream Brook, a canonical text in the study of the history of science in China and in the Notebook style of writing. Zuo argues, using a double-narrative structure, that Shen’s intellectual life and (...) career are fused in his scientific empiricism. This book is a complete study containing a List of Tables and Figures, three pages of Acknowledgments, a List of terms. (shrink)

Hace ya más de 40 años desde que se comenzase a explorar las posibilidades de emplear inteligencia artificial en el campo del derecho. Existen numerosos usos y propuestas en el marco de la IA y el derecho, desde la automatización de la búsqueda de la información jurídica hasta la personalización del derecho. Estas propuestas plantean diversas cuestiones relacionadas con la filosofía del derecho. La proliferación de propuestas, en ocasiones, dificulta identificar la relación existente entre cada una de ellas con debates (...) específicos de la filosofía del derecho. Este trabajo ofrece una clasificación de usos de la IA jurídica que facilita la identificación de los temas de filosofía de derecho especialmente afectados por cada uso. Se propone distinguir tres grandes categorías: derecho formalizado, práctica jurídica algorítmica, y derecho personalizado. Esta propuesta incorpora los avances recientes en machine learning y propuestas novedosas como la personalización del derecho. Con esta clasificación resulta más sencillo identificar las premisas iusfilosóficas en que se asientan o sobre las que deben reflexionar los diversos proyectos de empleo de IA en el derecho. (shrink)

Il ya quelques années, j’ai atteint le point où je peux généralement dire à partir du titre d’un livre, ou du moins à partir des titres chapitre, quels types d’erreurs philosophiques seront faites et à quelle fréquence. Dans le cas des travaux théoriquement scientifiques, ceux-ci peuvent être largement limités à certains chapitres qui cire philosophique ou essayer de tirer des conclusions générales sur le sens ou la signification à long terme de l’œuvre. Normalement, cependant, les questions scientifiques de fait sont (...) généreusement entrecoupées de charabia philosophique quant à ce que ces faits signifient. Les distinctions claires que Wittgenstein a décrites il y a environ 80 ans entre les questions scientifiques et leurs descriptions par divers jeux linguistiques sont rarement prises en considération, et on est donc tour à tour séduit par la science et consterné par son analyse incohérente. Il en est de même pour ce volume. Si l’on veut créer un esprit plus ou moins comme le nôtre, il faut avoir une structure logique de rationalité et une compréhension des deux systèmes de pensée (théorie du double processus). Si l’on veut philosopher à ce sujet, il faut comprendre la distinction entre les questions scientifiques de fait et la question philosophique de la façon dont le langage fonctionne dans le contexte en cause, et de la façon d’éviter les pièges du réductionnisme et du scientisme, mais Kurzweil, comme la plupart des étudiants de comportement, est largement désemparé. Il est enchanté par les modèles, les théories et les concepts, et l’envie d’expliquer, tandis que Wittgenstein nous a montré que nous n’avons qu’à décrire, et que les théories, les concepts, etc., ne sont que des moyens d’utiliser le langage (jeux linguistiques) qui n’ont de valeur que dans la mesure où ils ont un test clair (les véridiques clairs, ou comme John Searle (le critique le plus célèbre de l’IA) aime à dire, claire conditions de satisfaction (COS)). J’ai essayé de donner un début à ce sujet dans mes écrits récents. (shrink)

Ya desde los años sesenta, sólo un problema obsesionaba a Deleuze: el ejercicio del pensamiento, “¿qué significa pensar? ¿A qué llamamos pensar?”. Su preocupación se orientaba, por ello, a pensar de otro modo, de manera diferente. Su cometido era, en palabras de José Luis Pardo, “introducir una diferencia en la práctica de la filosofía”. Pero como preludio a esta tarea era preciso perder toda nuestra memoria, coagulada en palabras, prácticas y conceptos ya establecidos, era necesario alterar nuestros hábitos especulativos.

La confianza ciega ya no corre. Estamos en tiempos de crisis. La pérdida de confianza está generalizada, va desde lo privado a lo público. Pasa por las desconfianzas políticas, los organismos financieros y llega hasta nuestros líderes espirituales. La ruptura de la confianza, sobre todo ante situaciones de abuso, muchas veces parece definitiva, pero vivir en la total desconfianza es imposible. Conocido por haber denunciado públicamente los abusos de un poderoso sacerdote chileno, el filósofo José Andrés Murillo ha creado el (...) concepto de confianza lúcida, que limita con la desconfianza por un lado y con la confianza ciega por el otro. La confianza lúcida es el centro de este libro que surge en días marcados por el rechazo a los abusos de poder, la desconfianza, el miedo y la obsesión por la seguridad. Una declaración de principios según la cual ningún abuso tiene derecho a robar lo más preciado del ser humano: Confiar en otros y en uno mismo. (shrink)

It has often been argued that charitable donations are not a sufficient response to global poverty; individuals need to address structural injustice. Proponents of the Effective Altruism (EA) movement have raised two main problems with this focus on structural injustice. In this paper, we respond to these concerns. The first problem raised by EA proponents is that focusing on structural injustice absolves individuals of any responsibility other than political ones. In response, we argue that discharging this duty requires more commitment (...) than EA defenders think, and we do so by framing individual responsibility in global structural injustice through the lens of Robin Zheng’s Role-Ideal Model (RIM). The second response given by EA proponents is that a focus on structural injustice does not provide concrete ways for any given individual to discharge such duties. To address this worry, we argue that RIM can be complemented with the Rawlsian account of moral maturation. This new framework makes it clear how individuals can form the right concept of justice and become responsible citizens who act in accordance with RIM. (shrink)

Hace ya más de quince años que unos jóvenes cineastas dieron un giro inesperado al contexto cinematográfico uruguayo. Inés Bortagaray, figura clave del actual escenario cultural del país, formó parte de aquel fenómeno cuando, siendo estudiante de Ciencias de la Comunicación en la Universidad Católica del Uruguay, compartió clases, conversaciones sobre cine y buenos momentos de aprendizaje con un grupo de amigos que trastocarían el establishment del cine nacional afianzado durante años por la crítica conservadora. Inés Bortagaray nos habla de (...) su etapa de formación personal y artística junto a aquel grupo de amigos, pero también del significado del guion, de su proceso creativo en la soledad y en la compañía del director o de otros guionistas, y en definitiva, de la autoría compartida en aras de algo mayor: el cine. (shrink)

El problema antropológico ya está presente en Histoire de la folie, porque en la locura se objetiva una verdad antropológica, y por medio de la psicología el hombre fija una relación con su verdad científica a partir del loco. El hombre encuentra el primer acceso a su ser verdadero desde una experiencia de locura como objetivación espontánea de un enunciado antropológico. Por otro lado, los análisis de Foucault sobre la literatura le permiten transitar el problema antropológico a partir de una (...) serie de imágenes que dan cuenta de una "experiencia de la finitud". (shrink)