Results for 'Antoine C. Dussault'

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  1. Fitting-Attitude Analyses and the Relation Between Final and Intrinsic Value.Antoine C. Dussault - 2014 - Les ateliers de l'éthique/The Ethics Forum 9 (2):166-189.
    This paper examines the debate as to whether something can have final value in virtue of its relational (i.e., non-intrinsic) properties, or, more briefly put, whether final value must be intrinsic. The paper adopts the perspective of the fitting-attitude analysis (FA analysis) of value, and argues that from this perspective, there is no ground for the requirement that things may have final value only in virtue of their intrinsic properties, but that there might be some grounds for the alternate requirement (...)
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  2. Functional diversity: An epistemic roadmap.Christophe Malaterre, Antoine C. Dussault, Sophia Rousseau-Mermans, Gillian Barker, Beatrix E. Beisner, Frédéric Bouchard, Eric Desjardins, Tanya I. Handa, Steven W. Kembel, Geneviève Lajoie, Virginie Maris, Alison D. Munson, Jay Odenbaugh, Timothée Poisot, B. Jesse Shapiro & Curtis A. Suttle - 2019 - BioScience 10 (69):800-811.
    Functional diversity holds the promise of understanding ecosystems in ways unattainable by taxonomic diversity studies. Underlying this promise is the intuition that investigating the diversity of what organisms actually do—i.e. their functional traits—within ecosystems will generate more reliable insights into the ways these ecosystems behave, compared to considering only species diversity. But this promise also rests on several conceptual and methodological—i.e. epistemic—assumptions that cut across various theories and domains of ecology. These assumptions should be clearly addressed, notably for the sake (...)
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  3. L’art et la nature. [REVIEW]Ely Mermans & Antoine C. Dussault - 2016 - la Vie des Idées 1:1-6.
    À propos de : Catherine et Raphaël Larrère, Penser et agir avec la nature : Une enquête philosophique, Paris, La Découverte, 2015. -/- L’idée d’une nature sauvage à protéger des avancées techniques ne prend en compte ni la complexité des artefacts, ni ce qu’implique aujourd’hui la protection de la nature. En mettant l’accent sur la notion de biodiversité, C. et R. Larrère cherchent à donner un nouveau fondement à l’écologie politique.
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  4. Discussion of “Biomedical informatics: We are what we publish”.Geissbuhler Antoine, W. E. Hammond, A. Hasman, R. Hussein, R. Koppel, C. A. Kulikowski, V. Maojo, F. Martin-Sanchez, P. W. Moorman, Moura La, F. G. De Quiros, M. J. Schuemle, Barry Smith & J. Talmon - 2013 - Methods of Information in Medicine 52 (6):547-562.
    This article is part of a For-Discussion-Section of Methods of Information in Medicine about the paper "Biomedical Informatics: We Are What We Publish", written by Peter L. Elkin, Steven H. Brown, and Graham Wright. It is introduced by an editorial. This article contains the combined commentaries invited to independently comment on the Elkin et al. paper. In subsequent issues the discussion can continue through letters to the editor.
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  5. Less is more, more or less.Michel-Antoine Xhignesse - forthcoming - Metascience.
    Review of Felice C. Frankel's "The visual elements—design: a handbook for communicating science and engineering.".
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  6. L'enjeu des manifestations antiracistes de juin 2020: résonance médiatique ou resocialisation des populations majoritaires?Antoine Louette - 2022 - Les Cahiers de la Lcd 15 (1):45 à 63.
    En supposant que les manifestations antiracistes des 2 et 13 juin 2020 aient été l’occasion d’une prise de conscience du racisme structurel par les populations majoritaires, notamment en ce qui concerne les violences policières, cet article pose la question de son mécanisme. Le retentissement des manifestations de juin, sur les réseaux sociaux comme dans les « grands » médias, laisserait penser que c’est principalement en fournissant matière à une importante résonance médiatique qu’elles ont permis aux populations majoritaires de prendre conscience (...)
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  7. Quatremère de Quincy’s Moral Considerations on the Place and Purpose of Works of Art: Introduction and Translation. [REVIEW]Michel-Antoine Xhignesse - 2022 - Journal of Aesthetics and Art Criticism 80 (4):520-523.
    In 2006, David Carrier (Carrier, 2006, Museum Skepticism: A History of the Display of Art in Public Galleries. Durham: Duke University Press.) coined the term ‘museum skepticism’ to describe the idea that moving artworks into museum settings strips them of essential facets of their meaning; among art historians, this is better known as ‘decontextualization’, ‘denaturing’, or ‘museumization’. Although they do not usually name it directly, many contemporary debates in the philosophy of art are informed by an inclination towards museum skepticism, (...)
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  8. Marco P. Vianna Franco and Antoine Missemer, A History of Ecological Economic Thought (Oxfordshire: Routledge, 2022), pp. 200, 120£ (hardcover). ISBN: 9780367363925. [REVIEW]C. Tyler DesRoches - 2023 - Journal of the History of Economic Thought:1-3.
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  9. Biografia sobre René Descartes.Emanuel Isaque Cordeiro da Silva -
    RENÉ DESCARTES: UMA BIOGRAFIA -/- RENÉ DESCARTES: A BIOGRAPHY -/- Emanuel Isaque Cordeiro da Silva - CAP-UFPE, IFPE-BJ e UFRPE. E-mails: eisaque335@gmail.com e eics@discente.ifpe.edu.br. WhatsApp: (82)98143-8399. -/- -/- Nascido em 1596 em Haia, nas fronteiras de Touraine e Poitou, em uma família nobre, René Descartes vem ao mundo ao mesmo ano em que Johannes Kepler (1671-1630), em seu primeiro trabalho publicado (Mysterium cosmographicum), prova a superioridade da astronomia moderna (a de Nicolau Copérnico (1473-1543)) da astronomia antiga (a de Ptolomeu (90-168 (...)
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  10. Romanian diplomatic envoys to the United States of America.Alexandru Cristian - unknown - Encyclopedia of Romanian-American Relations.
    The very first permanent Romanian representation to the United States of America was established in Washington D.C. pursuant to the Royal Decree no. 1027 of 24 September 1917, led by Dr. Constantin Angelescu (1869-1948) in capacity as of head of legation with the rank of plenipotentiary minister. The game of history made it so that he took office on 15 January 1918 – the birth anniversary of our great Romanian poet Mihai Eminescu. The Secretary of the legation was Prince Anton (...)
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  11. The Groundless Normativity of Instrumental Rationality.Donald C. Hubin - 2001 - Journal of Philosophy 98 (9):445.
    Neo-Humean instrumentalist theories of reasons for acting have been presented with a dilemma: either they are normatively trivial and, hence, inadequate as a normative theory or they covertly commit themselves to a noninstrumentalist normative principle. The claimed result is that no purely instrumentalist theory of reasons for acting can be normatively adequate. This dilemma dissolves when we understand what question neo-Humean instrumentalists are addressing. The dilemma presupposes that neo-Humeans are attempting to address the question of how to act, 'simpliciter'. Instead, (...)
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  12. The Ethics of Vaccination Nudges in Pediatric Practice.Mark C. Navin - 2017 - HEC Forum 29 (1):43-57.
    Techniques from behavioral economics—nudges—may help physicians increase pediatric vaccine compliance, but critics have objected that nudges can undermine autonomy. Since autonomy is a centrally important value in healthcare decision-making contexts, it counts against pediatric vaccination nudges if they undermine parental autonomy. Advocates for healthcare nudges have resisted the charge that nudges undermine autonomy, and the recent bioethics literature illustrates the current intractability of this debate. This article rejects a principle to which parties on both sides of this debate sometimes seem (...)
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  13. What we talk about when we talk about epistemic justification.Jack C. Lyons - 2016 - Inquiry: An Interdisciplinary Journal of Philosophy 59 (7-8):867-888.
    Stewart Cohen argues that much contemporary epistemological theorizing is hampered by the fact that ‘epistemic justification’ is a term of art and one that is never given any serious explication in a non-tendentious, theory-neutral way. He suggests that epistemologists are therefore better off theorizing in terms of rationality, rather than in terms of ‘epistemic justification’. Against this, I argue that even if the term ‘epistemic justification’ is not broadly known, the concept it picks out is quite familiar, and partly because (...)
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  14. Philosophy for children meets the art of living: a holistic approach to an education for life.L. D'Olimpio & C. Teschers - 2016 - Philosophical Inquiry in Education 23 (2):114-124.
    This article explores the meeting of two approaches towards philosophy and education: the philosophy for children approach advocated by Lipman and others, and Schmid’s philosophical concept of Lebenskunst. Schmid explores the concept of the beautiful or good life by asking what is necessary for each individual to be able to develop their own art of living and which aspects of life are significant when shaping a good and beautiful life. One element of Schmid’s theory is the practical application of philosophy (...)
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  15. Fiat and Bona Fide Boundaries.Barry Smith & Achille C. Varzi - 2000 - Philosophy and Phenomenological Research 60 (2):401-420.
    There is a basic distinction, in the realm of spatial boundaries, between bona fide boundaries on the one hand, and fiat boundaries on the other. The former are just the physical boundaries of old. The latter are exemplified especially by boundaries induced through human demarcation, for example in the geographic domain. The classical problems connected with the notions of adjacency, contact, separation and division can be resolved in an intuitive way by recognizing this two-sorted ontology of boundaries. Bona fide boundaries (...)
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  16.  23
    Bien reçu? Trois éditions de Descartes au XIXe siècle en France.Delphine Antoine-Mahut - 2020 - Fabula 6551 (Accuser réception).
    Les études dites de réception se trouvent aujourd’hui dans une situation paradoxale. Au premier regard le tableau paraît souriant. Anciens ou modernes, les textes sont aujourd’hui communément abordés sous l’angle de leurs lectures immédiates (réception médiatique notamment) et, surtout, de leurs aménagements posthumes (avatars éditoriaux, propositions herméneutiques, usages sociaux). La multiplication de pareils travaux manifeste un engouement qui ne semble pas près de se démentir. Spectaculaire si l’on considère le nombre de thèses et de colloques qui entretiennent cette vague, pareil (...)
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  17. The ethics of expanding access to cheaper, less effective treatments.Govind C. Persad & Ezekiel J. Emanuel - 2016 - The Lancet (10047):S0140-6736(15)01025-9.
    This article examines a fundamental question of justice in global health. Is it ethically preferable to provide a larger number of people with cheaper treatments that are less effective (or more toxic), or to restrict treatments to a smaller group to provide a more expensive but more effective or less toxic alternative? We argue that choosing to provide less effective or more toxic interventions to a larger number of people is favored by the principles of utility, equality, and priority for (...)
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  18. Introduction: Debates on Experience and Empiricism in Nineteenth Century France.Delphine Antoine-Mahut & Silvia Manzo - 2019 - Perspectives on Science 27 (5):643-654.
    The lasting effects of the debate over canon-formation during the 1980s affected the whole field of Humanities, which became increasingly engaged in interrogating the origin and function of the Western canon. In philosophy, a great deal of criticism was, as a result, directed at the traditional narrative of seventeenth-and eighteenth-century philosophies—a critique informed by postcolonialism as well as feminist historiography. D. F. Norton, L. Loeb and many others1 attempted to demonstrate the weaknesses of the tripartite division between rationalism, empiricism and (...)
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  19. Inexplicit information.Robert C. Cummins - 1986 - In Myles Brand (ed.), The Representation Of Knowledge And Belief. Tucson: University Of Arizona Press.
    A discussion of a number of ways that information can be present in a computer program without being explicitly represented.
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  20. Science, method and critical thinking.Antoine Danchin - 2023 - Microbial Biotechnology 16 (10):1888-1894.
    Science is founded on a method based on critical thinking. A prerequisite for this is not only a sufficient command of language but also the comprehension of the basic concepts underlying our understanding of reality. This constraint implies an awareness of the fact that the truth of the World is not directly accessible to us, but can only be glimpsed through the construction of mod- els designed to anticipate its behaviour. Because the relationship between models and reality rests on the (...)
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  21. Parts, Wholes, and Part-Whole Relations: The Prospects of Mereotopology.Achille C. Varzi - 1996 - Data and Knowledge Engineering 20:259–286.
    We can see mereology as a theory of parthood and topology as a theory of wholeness. How can these be combined to obtain a unified theory of parts and wholes? This paper examines various non-equivalent ways of pursuing this task, with specific reference to its relevance to spatio-temporal reasoning. In particular, three main strategies are compared: (i) mereology and topology as two independent (though mutually related) chapters; (ii) mereology as a general theory subsuming topology; (iii) topology as a general theory (...)
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  22. Boundaries, continuity, and contact.Achille C. Varzi - 1997 - Noûs 31 (1):26-58.
    There are conflicting intuitions concerning the status of a boundary separating two adjacent entities (or two parts of the same entity). The boundary cannot belong to both things, for adjacency excludes overlap; and it cannot belong to neither, for nothing lies between two adjacent things. Yet how can the dilemma be avoided without assigning the boundary to one thing or the other at random? Some philosophers regard this as a reductio of the very notion of a boundary, which should accordingly (...)
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  23. Hagia Sophia.Wolf Leslau, C. F. Beckingham & G. W. B. Huntingford - manuscript
    Three separate churches erected in Constantinople were all dedicated to the wisdom of Christ and erected on the same site one after the other. These churches were built between 360 and 537 AD by three different emperors: Constantius II, Theodosius the Younger, and Justinian I. The first two churches were consumed in flames after relatively short lives, but the final and greatest church still stands today, despite a history of extensive damage. This final edifice is the main focus of this (...)
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  24. Vagueness in Geography.Achille C. Varzi - 2001 - Philosophy and Geography 4 (1):49–65.
    Some have argued that the vagueness exhibited by geographic names and descriptions such as ‘Albuquerque’, ‘the Outback’, or ‘Mount Everest’ is ultimately ontological: these terms are vague because they refer to vague objects, objects with fuzzy boundaries. I take the opposite stand and hold the view that geographic vagueness is exclusively semantic, or conceptual at large. There is no such thing as a vague mountain. Rather, there are many things where we conceive a mountain to be, each with its precise (...)
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  25. Hypothetical motivation.Donald C. Hubin - 1996 - Noûs 30 (1):31-54.
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  26. Irrational desires.Donald C. Hubin - 1991 - Philosophical Studies 62 (1):23 - 44.
    Many believe that the rational evaluation of actions depends on the rational evaluation of even basic desires. Hume, though, viewed desires as "original existences" which cannot be contrary to either truth or reason. Contemporary critics of Hume, including Norman, Brandt and Parfit, have sought a basis for the rational evaluation of desires that would deny some basic desires reason-giving force. I side with Hume against these modern critics. Hume's concept of rational evaluation is admittedly too narrow; even basic desires are, (...)
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  27. What’s Special about Humeanism.Donald C. Hubin - 1999 - Noûs 33 (1):30-45.
    One of the attractions of the Humean instrumentalist theory of practical rationality is that it appears to offer a special connection between an agent's reasons and her motivation. The assumption that Humeanism is able to assert a strong connection between reason and motivation has been challenged, most notably by Christine Korsgaard. She argues that Humeanism is not special in the connection it allows to motivation. On the contrary, Humean theories of practical rationality do connect reasons and motivation in a unique (...)
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  28. The Problem of Contraries and Prime Matter in the Reception of Aristotle’s Physical Corpus in the Work of Thomas Aquinas.Ana Maria C. Minecan - 2016 - Svmma Revista de Cultures Medievals 7:20-39.
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  29. Boundaries, Conventions, and Realism.Achille C. Varzi - 2011 - In Joseph Keim Campbell, Michael O'Rourke & Matthew H. Slater (eds.), Carving nature at its joints: natural kinds in metaphysics and science. Cambridge, MA, USA: MIT Press. pp. 129–153.
    Are there any bona fide boundaries, i.e., boundaries that carve at the joints? Or is any boundary —hence any object—the result of a fiat articulation reflecting our cognitive biases and our so-cial practices and conventions? Does the choice between these two options amount to a choice between realism and wholesome relativism?
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  30. “Jacob klapwijk’s invitation: Come to the party!” – Introduction by guest-editor.Bruce C. Wearne - 2011 - Philosophia Reformata 76 (1):1-10.
    This is the Guest Editor's Introduction to a volume of Philosophia Reformata that considers Jaap Klapwijk's book in which he seeks to discuss evolutionary biology in relation to Christian philosophy.
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  31. (1 other version)Dr. Henk E. S. Woldring. Karl Mannheim: the Development of his Thought Philosophy, Sociology and Social Ethics. Assen: Van Gorcum, 1986.Bruce C. Wearne - 1988 - Philosophia Reformata 53 (1):59-69.
    This is a review of Henk Woldring's book on Karl Mannheim.
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  32. Is there a future for AI without representation?Vincent C. Müller - 2007 - Minds and Machines 17 (1):101-115.
    This paper investigates the prospects of Rodney Brooks’ proposal for AI without representation. It turns out that the supposedly characteristic features of “new AI” (embodiment, situatedness, absence of reasoning, and absence of representation) are all present in conventional systems: “New AI” is just like old AI. Brooks proposal boils down to the architectural rejection of central control in intelligent agents—Which, however, turns out to be crucial. Some of more recent cognitive science suggests that we might do well to dispose of (...)
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  33. Events and Event Talk: An Introduction.Fabio Pianesi & Achille C. Varzi - 2000 - In James Higginbotham, Fabio Pianesi & Achille C. Varzi (eds.), Speaking of events. New York: Oxford University Press. pp. 3–47.
    A critical review of the main themes arising out of recent literature on the semantics of ordinary event talk. The material is organized in four sections: (i) the nature of events, with emphasis on the opposition between events as particulars and events as universals; (ii) identity and indeterminacy, with emphasis on the unifier/multiplier controversy; (iii) events and logical form, with emphasis on Davidson’s treatment of the form of action sentences; (iv) linguistic applications, with emphasis on issues concerning aspectual phenomena, the (...)
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  34. No wisdom in the crowd: genome annotation at the time of big data - current status and future prospects.Antoine Danchin - 2018 - Microbial Biotechnology 11 (4):588-605.
    Science and engineering rely on the accumulation and dissemination of knowledge to make discoveries and create new designs. Discovery-driven genome research rests on knowledge passed on via gene annotations. In response to the deluge of sequencing big data, standard annotation practice employs automated procedures that rely on majority rules. We argue this hinders progress through the generation and propagation of errors, leading investigators into blind alleys. More subtly, this inductive process discourages the discovery of novelty, which remains essential in biological (...)
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  35. Reasoning about Space: The Hole Story.Achille C. Varzi - 1996 - Logic and Logical Philosophy 4:3-39.
    This is a revised and extended version of the formal theory of holes outlined in the Appendix to the book "Holes and Other Superficialities". The first part summarizes the basic framework (ontology, mereology, topology, morphology). The second part emphasizes its relevance to spatial reasoning and to the semantics of spatial prepositions in natural language. In particular, I discuss the semantics of ‘in’ and provide an account of such fallacious arguments as “There is a hole in the sheet. The sheet is (...)
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  36. La guerre biologique au temps de la biologie synthétique.Antoine Danchin - 2023 - Raison Présente 225 (1):47-56.
    Dans un monde dominé par les conflits, il arrive qu’il faille se défendre. L’invention des armes a évolué en parallèle avec le savoir technique, puis scientifique, et il est même arrivé que la recherche d’applications militaires ait joué un rôle moteur dans la découverte scientifique. Lorsque les armes ne servent pas à attaquer d’autres nations, leur fabrication et leur commerce se justifient morale- ment. Il faut cependant qu’elles ne puissent échapper à ceux qui les construisent et doivent en contrôler la (...)
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  37. Kant, Herbart and Riemann.Erik C. Banks - 2005 - Kant Studien 96 (2):208-234.
    A look at the dynamical concept of space and space-generating processes to be found in Kant, J.F. Herbart and the mathematician Bernhard Riemann's philosophical writings.
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  38. Information of the chassis and information of the program in synthetic cells.Antoine Danchin - 2009 - Systems and Synthetic Biology 3:125-134.
    Synthetic biology aims at reconstructing life to put to the test the limits of our understanding. It is based on premises similar to those which permitted invention of computers, where a machine, which reproduces over time, runs a program, which replicates. The underlying heuristics explored here is that an authentic category of reality, information, must be coupled with the standard categories, matter, energy, space and time to account for what life is. The use of this still elusive category permits us (...)
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  39. Unsharpenable Vagueness.John Collins & Achille C. Varzi - 2000 - Philosophical Topics 28 (1):1-10.
    A plausible thought about vagueness is that it involves semantic incompleteness. To say that a predicate is vague is to say (at the very least) that its extension is incompletely specified. Where there is incomplete specification of extension there is indeterminacy, an indeterminacy between various ways in which the specification of the predicate might be completed or sharpened. In this paper we show that this idea is bound to founder by presenting an argument to the effect that there are vague (...)
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  40. Putting form before function: Logical grammar in Frege, Russell, and Wittgenstein.Kevin C. Klement - 2004 - Philosophers' Imprint 4:1-47.
    The positions of Frege, Russell and Wittgenstein on the priority of complexes over (propositional) functions are sketched, challenging those who take the "judgment centered" aspects of the Tractatus to be inherited from Frege not Russell. Frege's views on the priority of judgments are problematic, and unlike Wittgenstein's. Russell's views on these matters, and their development, are discussed in detail, and shown to be more sophisticated than usually supposed. Certain misreadings of Russell, including those regarding the relationship between propositional functions and (...)
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  41. SynBio 2.0, a new era for synthetic life: Neglected essential functions for resilience.Antoine Danchin & Jian Dong Huang - 2022 - Environmental Microbiology 25 (1):64-78.
    Synthetic biology (SynBio) covers two main areas: application engineering, exemplified by metabolic engi- neering, and the design of life from artificial building blocks. As the general public is often reluctant to embrace synthetic approaches, preferring nature to artifice, its immediate future will depend very much on the public’s reaction to the unmet needs created by the pervasive demands of sustainability. On the other hand, this reluctance should not have a negative impact on research that will now take into account the (...)
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  42. Supervaluationism and Paraconsistency.Achille C. Varzi - 2000 - In Diderik Batens, Chris Mortensen, Graham Priest & Jean Paul Van Bendegem (eds.), Frontiers in Paraconsistent Logic. Research Studies Press. pp. 279–297.
    Since its first appearance in 1966, the notion of a supervaluation has been regarded by many as a powerful tool for dealing with semantic gaps. Only recently, however, applications to semantic gluts have also been considered. In previous work I proposed a general framework exploiting the intrinsic gap/glut duality. Here I also examine an alternative account where gaps and gluts are treated on a par: although they reflect opposite situations, the semantic upshot is the same in both cases--the value of (...)
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  43. The Quest for universality: Reflections on the universal draft declaration on bioethics and human rights.Mary C. Rawlinson & Anne Donchin - 2005 - Developing World Bioethics 5 (3):258–266.
    ABSTRACT This essay focuses on two underlying presumptions that impinge on the effort of UNESCO to engender universal agreement on a set of bioethical norms: the conception of universality that pervades much of the document, and its disregard of structural inequalities that significantly impact health. Drawing on other UN system documents and recent feminist bioethics scholarship, we argue that the formulation of universal principles should not rely solely on shared ethical values, as the draft document affirms, but also on differences (...)
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  44. The number of senses.Kevin C. Klement - 2003 - Erkenntnis 58 (3):303 - 323.
    Many philosophers still countenance senses or meanings in the broadly Fregean vein. However, it is difficult to posit the existence of senses without positing quite a lot of them, including at least one presenting every entity in existence. I discuss a number of Cantorian paradoxes that seem to result from an overly large metaphysics of senses, and various possible solutions. Certain more deflationary and nontraditional understanding of senses, and to what extent they fare better in solving the problems, are also (...)
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  45. (1 other version)Conjunction and Contradiction.Achille C. Varzi - 2004 - In Graham Priest, Jc Beall & Bradley P. Armour-Garb (eds.), The law of non-contradiction : new philosophical essays. New York: Oxford University Press. pp. 93–110.
    There are two ways of understanding the notion of a contradiction: as a conjunction of a statement and its negation, or as a pair of statements one of which is the negation of the other. Correspondingly, there are two ways of understanding the Law of Non-Contradiction (LNC), i.e., the law that says that no contradictions can be true. In this paper I offer some arguments to the effect that on the first (collective) reading LNC is non-negotiable, but on the second (...)
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  46. Antifragility and Tinkering in Biology (and in Business) Flexibility Provides an Efficient Epigenetic Way to Manage Risk.Antoine Danchin, Philippe M. Binder & Stanislas Noria - 2011 - Genes 2 (4):998-1016.
    The notion of antifragility, an attribute of systems that makes them thrive under variable conditions, has recently been proposed by Nassim Taleb in a business context. This idea requires the ability of such systems to ‘tinker’, i.e., to creatively respond to changes in their environment. A fairly obvious example of this is natural selection-driven evolution. In this ubiquitous process, an original entity, challenged by an ever-changing environment, creates variants that evolve into novel entities. Analyzing functions that are essential during stationary-state (...)
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  47.  94
    Artificial intelligence-based prediction of pathogen emergence and evolution in the world of synthetic biology.Antoine Danchin - 2024 - Microbial Biotechnology 17 (10):e70014.
    The emergence of new techniques in both microbial biotechnology and artificial intelligence (AI) is opening up a completely new field for monitoring and sometimes even controlling the evolution of pathogens. However, the now famous generative AI extracts and reorganizes prior knowledge from large datasets, making it poorly suited to making predictions in an unreliable future. In contrast, an unfamiliar perspective can help us identify key issues related to the emergence of new technologies, such as those arising from synthetic biology, whilst (...)
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  48. Basic Problems of Mereotopology.Achille C. Varzi - 1998 - In Nicola Guarino (ed.), Formal Ontology in Information Systems. IOS Press. pp. 29–38.
    Mereotopology is today regarded as a major tool for ontological analysis, and for many good reasons. There are, however, a number of open questions that call for an answer. Some are philosophical, others have direct applicative import, but all are crucial for a proper assessment of the strengths and limits of mereotopology. This paper is an attempt to put sum order in this area.
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  49. Three overlooked key functional classes for building up minimal synthetic cells.Antoine Danchin - 2021 - Synthetic Biology 6 (1):ysab010.
    Assembly of minimal genomes revealed many genes encoding unknown functions. Three overlooked functional categories account for some of them. Cells are prone to make errors and age. As a first key function, discrimination between proper and changed entities is indispensable. Discrimination requires management of information, an authentic, yet abstract, cur- rency of reality. For example proteins age, sometimes very fast. The cell must identify, then get rid of old proteins without destroying young ones. Implementing discrimination in cells leads to the (...)
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  50. Motivated research.Antoine Danchin - 2010 - EMBO Reports 11 (7):488.
    The dichotomy between the research to generate knowledge and the application of that knowledge to benefit mankind seems to be a recent development. In fact, more than 100 years ago Louis Pasteur avoided this debate altogether: one of his major, yet forgotten, contributions to science was the insight that research and its applications are not opposed, but orthogonal to each other (Stokes, 1997). If Niels Bohr ‘invented’ basic academic research—which was nevertheless the basis for many technological inventions and industrial applications—Pasteur (...)
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