The desideratum of semantic interoperability has been intensively discussed in medical informatics circles in recent years. Originally, experts assumed that this issue could be sufficiently addressed by insisting simply on the application of shared clinical terminologies or clinical information models. However, the use of the term ‘ontology’ has been steadily increasing more recently. We discuss criteria for distinguishing clinical ontologies from clinical terminologies and information models. Then, we briefly present the role clinical ontologies play in two multicentric research projects. Finally, (...) we discuss the interactions between these different kinds of knowledge representation artifacts and the stakeholders involved in developing interoperational real-world clinical applications. We provide ontology engineering examples from two EU-funded projects. (shrink)

Propomos uma tipologia dos artefatos de representação para as áreas de saúde e ciências biológicas, e a associação dessa tipologia com diferentes tipos de ontologia formal e lógica, chegando a conclusões quanto aos pontos fortes e limitações da ontologia de diferentes tipos de recursos lógicos, enquanto mantemos o foco na lógica descritiva. Consideramos quatro tipos de representação de área: (i) representação léxico-semântica, (ii) representação de tipos de entidades, (iii) representação de conhecimento prévio, e (iv) representação de indivíduos. Defendemos uma clara (...) distinção entre os quatro tipos de representação, de forma a oferecer uma base mais racional para o uso das ontologias e artefatos relacionados no avanço da integração de dados e interoperabilidade de sistemas de raciocínio associados. Destacamos que apenas uma pequena porção de fatos cientificamente relevantes em áreas como a biomedicina pode ser adequadamente representada por ontologias formais, quando estas últimas são concebidas como representações de tipos de entidades. Particularmente, a tentativa de codificar conhecimento padrão ou probabilístico pela utilização de ontologias assim concebidas é fadada à produção de modelos não intencionais e errôneos. (shrink)

The desideratum of semantic interoperability has been intensively discussed in medical informatics circles in recent years. Originally, experts assumed that this issue could be sufficiently addressed by insisting simply on the application of shared clinical terminologies or clinical information models. However, the use of the term ‘ontology’ has been steadily increasing more recently. We discuss criteria for distinguishing clinical ontologies from clinical terminologies and information models. Then, we briefly present the role clinical ontologies play in two multicentric research projects. Finally, (...) we discuss the interactions between these different kinds of knowledge representation artifacts and the stakeholders involved in developing interoperational real-world clinical applications. We provide ontology engineering examples from two EU-funded projects. (shrink)

Most epistemologists hold that knowledge entails belief. However, proponents of this claim rarely offer a positive argument in support of it. Rather, they tend to treat the view as obvious and assert that there are no convincing counterexamples. We find this strategy to be problematic. We do not find the standard view obvious, and moreover, we think there are cases in which it is intuitively plausible that a subject knows some proposition P without—or at least without determinately—believing that P. Accordingly, (...) we present five plausible examples of knowledge without (determinate) belief, and we present empirical evidence suggesting that our intuitions about these scenarios are not atypical. (shrink)

In this paper, we propose a regularity theory of causation. The theory aims to be reductive and to align with our pre‐theoretic understanding of the causal relation. We show that our theory can account for a wide range of causal scenarios, including isomorphic scenarios, omissions, and scenarios which suggest that causation is not transitive.

During much of the past century, it was widely believed that phonemes--the human speech sounds that constitute words--have no inherent semantic meaning, and that the relationship between a combination of phonemes (a word) and its referent is simply arbitrary. Although recent work has challenged this picture by revealing psychological associations between certain phonemes and particular semantic contents, the precise mechanisms underlying these associations have not been fully elucidated. Here we provide novel evidence that certain phonemes have an inherent, non-arbitrary emotional (...) quality. Moreover, we show that the perceived emotional valence of certain phoneme combinations depends on a specific acoustic feature--namely, the dynamic shift within the phonemes' first two frequency components. These data suggest a phoneme-relevant acoustic property influencing the communication of emotion in humans, and provide further evidence against previously held assumptions regarding the structure of human language. This finding has potential applications for a variety of social, educational, clinical, and marketing contexts. (shrink)

Recent developments under the keywords dynamicism, embodiment and situated cognition suggest the view that cognitive systems are not confined to the neural sys‐tem but leak into the world beyond the traditional system boundaries. This is the thesis of extended cognition. Such an extension of the cognitive vehicles leads to a new kind of content externalism, known as active externalism. The essay pursues three objectives: firstly, to distinguish the theses of extended cognitive and active externalism. Secondly, to delineate active externalism from (...) its various passive-externalist precursors in the form of physical, historical and social externalism and to scrutinize its special position, which amounts to a comprehensive discussion and analysis of all variants of mental externalism. And thirdly, to show that social externalism as opposed to physical and historical externalism allows for a gradual transition from passive to active mental externalism. (shrink)

Multiple Realizability (MR) must still be regarded as one of the principal arguments against type reductionist accounts of higher-order properties and their special laws. Against this I argue that there is no unique MR but rather a multitude of MR categories. In a slogan: MR is itself “multi-realized”. If this is true then we cannot expect one unique reductionist strategy against MR as an anti-reductionist argument. The main task is rather to develop a taxonomy of the wide variety of MR (...) cases and to sketch possible reductionist answers for each class of cases. The paper outlines some first steps in this direction. (shrink)

In this paper, we analyse actual causation in terms of production. The latter concept is made precise by a strengthened Ramsey Test semantics of conditionals: \ iff, after suspending judgement about A and C, C is believed in the course of assuming A. This test allows us to verify or falsify that an event brings about another event. Complementing the concept of production by a weak condition of difference-making gives rise to a full-fledged analysis of causation.

Statements about the behavior of biochemical entities (e.g., about the interaction between two proteins) abound in the literature on molecular biology and are increasingly becoming the targets of information extraction and text mining techniques. We show that an accurate analysis of the semantics of such statements reveals a number of ambiguities that have to be taken into account in the practice of biomedical ontology engineering: Such statements can not only be understood as event reporting statements, but also as ascriptions of (...) dispositions or tendencies that may or may not refer to collectives of interacting molecules or even to collectives of interaction events. (shrink)

We define a formal semantics of conditionals based on _normatively ideal worlds_. Such worlds are described informally by Armgardt (Gabbay D, Magnani L, Park W, Pietarinen A-V (eds) Natural arguments: a tribute to john woods, College Publications, London, pp 699–708, 2018) to address well-known problems of the counterfactual approach to causation. Drawing on Armgardt’s proposal, we use iterated conditionals in order to analyse causal relations in scenarios of multi-agent interaction. This results in a refined counterfactual approach to causal responsibility in (...) legal contexts, which solves overdetermination problems in an intuitively accessible manner. (shrink)

The well-known formal semantics of conditionals due to Stalnaker Studies in logical theory, Blackwell, Oxford, 1968), Lewis, and Gärdenfors The logic and 1140 epistemology of scientific change, North-Holland, Amsterdam, 1978, Knowledge in flux, MIT Press, Cambridge, 1988) all fail to distinguish between trivially and nontrivially true indicative conditionals. This problem has been addressed by Rott :345–370, 1986) in terms of a strengthened Ramsey Test. In this paper, we refine Rott’s strengthened Ramsey Test and the corresponding analysis of explanatory relations. We (...) show that our final analysis captures the presumed asymmetry between explanans and explanandum much better than Rott’s original analysis. (shrink)

We will explicate Cantor’s principle of set existence using the Gödelian intensional notion of absolute provability and John Burgess’ plural logical concept of set formation. From this Cantorian Comprehension principle we will derive a conditional result about the question whether there are any absolutely unprovable mathematical truths. Finally, we will discuss the philosophical significance of the conditional result.

The aim of this paper is to scrutinize active externalism and its repercussions for externalism about mental content. I start from the claim that active externalism is a version of content externalism that follows from the extended cognition thesis as a thesis about cognitive vehicles. Various features of active content externalism are explored by comparison with the known forms of passive externalism – in particular with respect to the multiple realizability of the relevant external content-determining components and with respect to (...) mental causation. A crucial result is that social externalism is already a version of active externalism. I conclude with a first sketch of a general account of meaning inspired by extended cognition: a use theory supplemented by a functional-role account. (shrink)

Gegenstand dieses Beitrags ist eine Auseinandersetzung mit der Wissenschaftlichkeit der Medizin. Den Leitfaden der Analyse bildet dabei ein jüngerer Ansatz in der analytischen Wissenschaftstheorie, wonach Systematizität als zentrales Kriterium von Wissenschaft anzusehen ist (Hoyningen-Huene 2013). Ich werde im Detail zeigen, dass die Medizin dieses mehrdimensionale Kriterium insgesamt erfüllt, dass aus der Wissenschaftlichkeit der Medizin aber gleichwohl normative Konsequenzen folgen, die beispielsweise zur Abgrenzung von der Homöopathie und einer kritischen Bewertung des biopsychosozialen Modells führen. Zudem resultieren der Anwendungscharakter der Medizin und (...) die zentrale Bedeutung des Arzt-Patienten-Verhältnisses nicht in einer Schwächung des Anspruchs der Medizin als Wissenschaft. (shrink)

Statements about the behavior of biological entities, e.g. about the interaction between two proteins, abound in the literature on molecular biology and are increasingly becoming the targets of information extraction and text mining techniques. We show that an accurate analysis of the semantics of such statements reveals a number of ambiguities that is necessary to take into account in the practice of biomedical ontology engineering. Several concurring formalizations are proposed. Emphasis is laid on the discussion of biological dispositions.

Structural Realism (SR) is typically rated as a moderate realist doctrine about the ultimate entities of nature described by fundamental physics. Whether it must be extended to the higher-level special sciences is not so clear. In this short paper I argue that there is no need to ‘structuralize’ the special sciences. By mounting concrete examples I show that structural descriptions and structural laws certainly play a role in the special sciences, but that they don’t play any exclusive role nor that (...) they give us any reason to believe that all that there is on the various levels is structure. I fortify my points by arguing that structures are global entities (in order for SR not to collapse into a bundle ontology) and that the assumption of higher-level structures as genuinely global or holistic entities is even more arcane. (shrink)

According to the Thomistic tradition, the Principle of Totality (TPoT) articulates a secondary principle of natural law which guides the exercise of human ownership or dominium over creation. In its general signification, TPoT is a principle of distributive justice determining the right ordering of wholes to their parts. In the medical field it is traditionally understood as entailing an absolute prohibition of bodily mutilation as irrational and immoral, and an imperfect obligation to use the parts of one’s body for the (...) perfection of the bodily whole. TPoT is thus a key element of the system of principles within which an individual exercises her right to life: it helps specify the nature, scope and limits of those actions by which an agent permissibly acts in order to preserve her life. While the Thomistic tradition and the Catholic Church have drawn clear conclusions from the principle regarding, e.g., direct sterilization and non-therapeutic experimentation on human subjects, less attention has been given to the implications of TPoT for non-therapeutic procedures that may positively impact biological functioning or supra-biological goals–that is, for human “enhancement.” We will explore the degree to which TPoT non-univocally guides our use of both artifacts and bodies. We will argue that a careful analysis of these distinct kinds of totalities suggests that the application of TPoT to artifacts and bodies is strongly isomorphic, which is what tempts advocates of the Principle of Autonomy to invalidly infer the absolute dominium of the individual over her body. The inference is invalid because this isomorphism also includes a principle of intrinsic value whose function is to resist the instrumentalization of both artifacts and bodies in some contexts; we are not even related to artifacts as advocates of absolute autonomy believe we are, let alone to our bodies. Rather, the limits of human dominium are determined by the nature and finalities, inherent or acquired, of the objects in question, and it will be argued that articulating these limits raises important, understudied, and fascinating questions about the permissibility of various kinds of human enhancement. (shrink)

The pivotal role of the relation part-of in the description of living organisms is widely acknowledged. Organisms are open systems, which means that in contradistinction to mechanical artifacts they are characterized by a continuous flow and exchange of matter. A closer analysis of the spatial relations in biological organisms reveals that the decision as to whether a given particular is part-of a second particular or whether it is only contained-in the second particular is often controversial. We here propose a rule-based (...) approach which allows us to decide on the basis of well-defined criteria which of the two relations holds between two anatomical objects, given that one spatially includes the other. We discuss the advantages and limitations of this approach, using concrete examples from human anatomy. (shrink)

In der modernen Physik spielen Symmetrien eine herausragende Rolle zur Identifikation und Klassifizierung der fundamentalen Theorien und Entitäten. Symmetrien dienen der Darstellung invarianter Strukturen, das geeignete mathematische Werkzeug hierfür ist die Gruppentheorie. Eine Struktur lässt sich als eine Menge von Relationen verstehen, die einer Menge von Objekten aufgeprägt sind. Strukturell charakterisierte Objekte sind daher wesentlich über ihre relationalen Eigenschaften charakterisiert. Sieht man die theoretischen Entitäten wissenschaftlicher Theorien vornehmlich in dieser strukturellen Weise an, vertritt man eine moderate Variante eines wissenschaftlichen Realismus, (...) die als Strukturenrealismus bekannt ist. Im Umfeld dieser drei Konzepte – Symmetrien, Strukturen, Realismus – bewegt sich der folgende Aufsatz. (shrink)

The paper presents and discusses the “which-is-which content of handedness,” the meaning of left as left and right as right, as a possible candidate for the idea of a genuine embodied cognitive content. After showing that the Ozma barrier, the non-transferability of the meaning of left and right, provides a kind of proof of the non-descriptive, indexical nature of the which-is-which content of handedness, arguments are presented which suggest that the classical representationalist account of cognition faces a perplexing problem of (...) underdetermination of reference of left and right in the which-is-which sense. By way of contrast, no such problems occur in a framework were embodied contents are not mediated by some extra body model which carries the representational power, but are instead directly represented. (shrink)

Im ersten Abschnitt illustrierte ich die These der erweiterten Kognition und diskutiere einige mögliche Missverständnisse. Im zweiten Abschnitt werde ich vier Domänen kognitiver Erweiterung auseinanderhalten, nämlich eine Erweiterung in die körperliche, physikalische, 'informatorische' und soziale Umgebung betreffend. Um die These der erweiterten Kognition vor dem Einwand der kognitiven Inflation zu schützen, muss man für jeden dieser Bereiche (und gegebenenfalls noch spezieller) spezifische Bedingungen und Mechanismen der kognitiven Kopplung an die externen Komponenten angeben. Im dritten Abschnitt unterscheide ich die These der (...) erweiterten Kognition, von der sich im ersten Abschnitt bereits zeigen wird, dass sie eine These kognitiver Vehikel ist, von einer externalistischen Gehaltsthese. Letztere bezeichne ich im Anklang an Clark und Chalmers als aktiven Externalismus und illustriere dessen Unterschiede und Besonderheiten gegenüber den bekannten 'passiven' Formen des semantischen oder mentalen Externalismus in der Philosophie des Geistes, die sich mit den Namen Putnam, Millikan und Burge verbinden. Im vierten Abschnitt verfolge ich die spezifische Idee, die Mechanismen geteilter Intentionalität als Kopplungsmechanismen kognitiver Erweiterung in die soziale Umgebung, speziell soziale Interaktionspartner, anzusehen. Dazu mache ich in einigem Detail von Bratmans bekannter Plan-Konzeption geteilter Intentionalität Gebrauch. Anhand der Ergebnisse dieser Analyse wird sich im fünften und letzten Abschnitt zeigen, in welchem Sinne es sich dabei im Keim bereits um einen sozialen Externalismus handelt. Der soziale Externalismus, so der Clou, stellt bereits eine verkappte Variante eines aktiven Externalismus dar. (shrink)

The paper deals with Weizsäcker’s position within the philosophy of mind. It turns out that Weizsäcker’s ontology is based on an unorthodox conception both in the philosophy of physics and in the philosophy of mind. His quantum information theoretic reductionism is based on a subtle combination of atomism and holism, his philosophy of mind connected to this is a neutral monism, which proposes a bold intertwining of mind, matter, and space.

Der Aufsatz lotet den zeitgenössischen Reduktionismus aus. Im ersten Teil wird in zentrale Stationen der wissenschaftstheoretischen Debatte um Theorien-Reduktion eingeleitet, wobei das Schaffner-Hooker-Modell und die Bedeutung von Näherungsbegriffen hervorgehoben werden. Der zweite Teil behandelt die multiple Realisierbarkeit als eines der nach wie vor zentralen anti-reduktionistischen Argumente. Die Analyse soll zeigen, dass es sich hierbei nicht um ein einheitliches Phänomen handelt, sondern dass sehr verschiedene Kategorien von Multirealisierbarkeit zu unterscheiden sind. In einem vereinfachten Slogan: multiple Realisierbarkeit ist ihrerseits multirealisiert. Der Aufsatz (...) entwickelt eine rohe Taxonomie von Typen multipler Realisierbarkeit und möglicher reduktionistischer Strategien, wobei genuine Fälle von Multirealisierbarkeit auf geteilte Eigenschaften zurückgeführt werden. Im letzten Teil wird die besondere Rolle von Näherungen im Zusammenhang mit der explanatorischen Spannung zwischen ontischem Reduktionismus und epistemischen Anti-Reduktionismus verdeutlicht. (shrink)

Dieser Band versammelt Beiträge zu den drei klassischen Disziplinen der Philosophie – dem Wahren, dem Guten, dem Schönen. Ihre Autoren zeichnet aus, dass sie aus dem akademischen Umfeld Michael Sukales zu seiner Zeit am Institut für Philosophie an der Carl-von-Ossietzky-Universität Oldenburg stammen. Ihm ist dieses Buch zum Abschied von seiner aktiven Lehrtätigkeit in Oldenburg gewidmet. Die thematische Vielfalt der enthaltenen Texte spiegelt die Bandbreite seines philosophischen Schaffens wider.

Landgrebe and Smith provide an argument for the impossibility of Artificial General Intelligence based on the limits of simulating complex systems. However, their argument presupposes a very contemporary vision of artificial intelligence as a model trained on data to produce an algorithm executable in a modern digital computing system. The present contribution explores what it means to be artificial. Current artificial intelligence approaches on modern computing systems are not the only conceivable way in which artificial intelligence technology might be created. (...) If there are conceivable routes by which an artificial intelligence might be developed that are not constrained in the same way as the current generation of artificial neural networks, then these might be plausible routes towards the engineered generation of artificial general intelligence that are not precluded by the Landgrebe and Smith argument against the possibility of artificial general intelligence. (shrink)

The integration of standardized biomedical terminologies into a single, unified knowledge representation system has formed a key area of applied informatics research in recent years. The Unified Medical Language System (UMLS) is the most advanced and most prominent effort in this direction, bringing together within its Metathesaurus a large number of distinct source-terminologies. The UMLS Semantic Network, which is designed to support the integration of these source-terminologies, has proved to be a highly successful combination of formal coherence and broad scope. (...) We argue here, however, that its organization manifests certain structural problems, and we describe revisions which we believe are needed if the network is to be maximally successful in realizing its goals of supporting terminology integration. (shrink)

Problems in normative ethics paradigmatically concern what it is obligatory or permissible for an individual to do. Yet sometimes, each of us ought to do something individually in virtue of what we ought to do together. Unfortunately, traversing these two different levels at which a moral obligation can arise – individual and collective – is fraught with difficulties that easily lure us into conclusions muddying our understanding of collective obligations. This paper seeks to clearly lay out a systematic problem central (...) to the relation between collective and individual duties in view of alleviating some such confusion and facilitating more concerted attempts at resolving it: Collective duties require individuals to act in order for the collective duty to be fulfilled. Yet typically, a collective duty does not entail any one set of individual duties that would prescribe such contributory actions: The work we need to do in order to fulfil a duty can be allocated differently to the individuals collectively bearing it. Much like in matters of distributive justice, then, deriving individual duties from a collective one requires us to employ a distributive scheme, which raises separate normative concerns that have rarely taken centre stage in the debate so far. (shrink)

How a Semantic Search Algorithm for unedited sources may look. - The basics for the Philosophy Dictionary of Arguments.

Where humans can manipulate and integrate the information they receive in subtle and ever changing ways from context to context, computers need structured and context-free background information of a sort which ontologies can help to provide. A domain ontology captures the stable, highly general and commonly accepted core knowledge for an application domain. The domain at issue here is that of the life sciences, in particular molecular biology and bioinformatics. Contemporary life science research includes components drawn from physics, chemistry, mathematics, (...) medicine and many other areas, and all of these dimensions, as well as fundamental philosophical issues, must be taken into account in the construction of a domain ontology. Here we describe the basic features of domain ontologies in the life sciences and show how they can be used. (shrink)

Where humans can manipulate and integrate the information they receive in subtle and ever-changing ways from context to context, computers need structured and context-free background information of a sort which ontologies can help to provide. A domain ontology captures the stable, highly general and commonly accepted core knowledge for an application domain. The domain at issue here is that of the life sciences, in particular molecular biology and bioinformatics. Contemporary life science research includes components drawn from physics, chemistry, mathematics, medicine (...) and many other areas, and all of these dimensions, as well as fundamental philosophical issues, must be taken into account in the construction of a domain ontology. Here we describe the basic features of domain ontologies in the life sciences and show how they can be used. (shrink)

This is a proposal for rethinking the main lines of Plato’s philosophy, including some of the conceptual tools he uses for building and maintaining it. Drawing on a new interpretive paradigm for Plato’s overall vision, the central focus is on the so-called Forms. Regarding the guiding paradigm, we propose replacing the dualism of a world of Forms separated from a world of particulars, with the monistic model of a hierarchically structured universe comprising interdependent levels of reality. Regarding the tools of (...) the trade, we distinguish between three constructs that have come, one and all, and largely indiscriminately, to be regarded as Forms: Ideal Forms, Conceptual Forms, and Relational Forms. This recalibration of what we know of Plato’s outlook, tools, and methods, together with a realignment of these with his general aims, will also help restore the philosopher’s emphasis on that which is good, a perspective often blurred in the structure of two worlds. (shrink)

The Foundational Model of Anatomy (FMA) is a map of the human body. Like maps of other sorts – including the map-like representations we find in familiar anatomical atlases – it is a representation of a certain portion of spatial reality as it exists at a certain (idealized) instant of time. But unlike other maps, the FMA comes in the form of a sophisticated ontology of its objectdomain, comprising some 1.5 million statements of anatomical relations among some 70,000 anatomical kinds. (...) It is further distinguished from other maps in that it represents not some specific portion of spatial reality (say: Leeds in 1996), but rather the generalized or idealized spatial reality associated with a generalized or idealized human being at some generalized or idealized instant of time. It will be our concern in what follows to outline the approach to ontology that is represented by the FMA and to argue that it can serve as the basis for a new type of anatomical information science. We also draw some implications for our understanding of spatial reasoning and spatial ontologies in general. (shrink)

This essay articulates and defends Aristotle’s argument in Politics 7.4 that there is a rational limit to the size of the political community. Aristotle argues that size can negatively affect the ability of an organized being to attain its proper end. After examining the metaphysical grounds for this principle in both natural beings and artifacts, we defend Aristotle’s extension of the principle to the polis. He argues that the state is in the relevant sense an organism, one whose primary end (...) is to make good reasons available to individuals and promote them as choiceworthy. The size of a polis can affect its ability to perform this function, since growth promotes anonymity among citizens, which in turn frustrates the familiarity between citizens required for the exercise of distributive and restorative justice as well as political prudence. This paper suggests several ways in which Aristotle’s argument, if sound, is important for contemporary issues in moral psychology, Ralwsian political philosophy, and big data analytics. (shrink)

I develop a distinction between two types of psychological hedonism. Inferential hedonism (or “I-hedonism”) holds that each person only has ultimate desires regarding his or her own hedonic states (pleasure and pain). Reinforcement hedonism (or “R–hedonism”) holds that each person's ultimate desires, whatever their contents are, are differentially reinforced in that person’s cognitive system only by virtue of their association with hedonic states. I’ll argue that accepting R-hedonism and rejecting I-hedonism provides a conciliatory position on the traditional altruism debate, and (...) that it coheres well with the neuroscientist Anthony Dickinson’s theory about the evolutionary function of hedonic states, the “hedonic interface theory.” Finally, I’ll defend R-hedonism from potential objections. (shrink)

In this article I argue that including relaxed epistemic values in the justification of democracy through a pragmatist and non-monist approach is compatible with the democratic values of self-rule and pluralism (which are often seen as incompatible with "political truth"). First, I contend that pragmatist epistemology offers a more suitable approach to politics instead of the correspondence theory of finding "the one truth". Secondly, I argue that instead of choosing between monist (purely epistemic or procedural) accounts of justification of democracy (...) we should see epistemic values as part of a hybrid interpretation. Thirdly, I argue that epistemic values in democracy should be interpreted in a non-demanding way. Fourth and corresponding to previous points, I claim weak political cognitivism is phenomenologically most plausible for the democratic participant. I then continue to show that both the values of autonomy and pluralism, which are often considered antithetical to truth-claims, can be accommodated and even enhanced by epistemic values in the justification of democracy. (shrink)

The rapidly increasing wealth of genomic data has driven the development of tools to assist in the task of representing and processing information about genes, their products and their functions. One of the most important of these tools is the Gene Ontology (GO), which is being developed in tandem with work on a variety of bioinformatics databases. An examination of the structure of GO, however, reveals a number of problems, which we believe can be resolved by taking account of certain (...) organizing principles drawn from philosophical ontology. We shall explore the results of applying such principles to GO with a view to improving GO’s consistency and coherence and thus its future applicability in the automated processing of biological data. (shrink)

Welche Theorien widersprechen einander? Welcher Autor ist welcher Theorie zuzuordnen? Wo gibt es stillschweigende Kontroversen und Übereinstimmungen? Wo verlaufen die wissenschaftlichen Lager? Die Grundlagen für das Lexikon der Argumente.

Wie könnte ein Suchalgorithmus für wissenschaftliche Quellen aussehen? Wie findet man nicht erwähnte Begriffe? Wie erschließen sich implizite Kontroversen? Die Grundlagen für das Lexikon der Argumente.

The Basics for the Philosophy Dictionary of Arguments - How to find non-mentioned concepts.

In this paper we present applications of the ACGT Master Ontology (MO) which is a new terminology resource for a transnational network providing data exchange in oncology, emphasizing the integration of both clinical and molecular data. The development of a new ontology was necessary due to problems with existing biomedical ontologies in oncology. The ACGT MO is a test case for the application of best practices in ontology development. This paper provides an overview of the application of the ontology within (...) the ACGT project thus far. (shrink)

Previous research in Explainable Artificial Intelligence (XAI) suggests that a main aim of explainability approaches is to satisfy specific interests, goals, expectations, needs, and demands regarding artificial systems (we call these “stakeholders' desiderata”) in a variety of contexts. However, the literature on XAI is vast, spreads out across multiple largely disconnected disciplines, and it often remains unclear how explainability approaches are supposed to achieve the goal of satisfying stakeholders' desiderata. This paper discusses the main classes of stakeholders calling for explainability (...) of artificial systems and reviews their desiderata. We provide a model that explicitly spells out the main concepts and relations necessary to consider and investigate when evaluating, adjusting, choosing, and developing explainability approaches that aim to satisfy stakeholders' desiderata. This model can serve researchers from the variety of different disciplines involved in XAI as a common ground. It emphasizes where there is interdisciplinary potential in the evaluation and the development of explainability approaches. (shrink)

Recreational Drugs European Network (ReDNet) project aims to use the Psychonaut Web Mapping Project database (Psychonaut Web Mapping Group, 2009) containing novel psychoactive compounds usually not mentioned in the scientific literature and thus unknown to clinicians as a unique source of information. The database will be used to develop an integrated ICT prevention approach targeted at vulnerable individuals and focused on novel synthetic and herbal compounds and combinations. Particular care will be taken in keeping the health professionals working directly with (...) young people showing problematic behaviors regularly updated in terms of novel compounds and combinations as well. A user-friendly project website will be developed aimed primarily at delivering the information/prevention approaches, but will also be a way of communicating with project partners and relevant stakeholders (e.g. thematic forum facilities, instant messages, blogs, video chat, wikiblog, newsletters distributed via mailing list). The website will support various ICT prevention tools, including an SMS alert service. Different areas and sections will be aimed specifically at the different target groups. -/- . (shrink)

The translational research community, in general, and the Clinical and Translational Science Awards (CTSA) community, in particular, share the vision of repurposing EHRs for research that will improve the quality of clinical practice. Many members of these communities are also aware that electronic health records (EHRs) suffer limitations of data becoming poorly structured, biased, and unusable out of original context. This creates obstacles to the continuity of care, utility, quality improvement, and translational research. Analogous limitations to sharing objective data in (...) other areas of the natural sciences have been successfully overcome by developing and using common ontologies. This White Paper presents the authors’ rationale for the use of ontologies with computable semantics for the improvement of clinical data quality and EHR usability formulated for researchers with a stake in clinical and translational science and who are advocates for the use of information technology in medicine but at the same time are concerned by current major shortfalls. This White Paper outlines pitfalls, opportunities, and solutions and recommends increased investment in research and development of ontologies with computable semantics for a new generation of EHRs. (shrink)