Theoretical arguments and empirical investigations indicate that a high proportion of published findings do not replicate and are likely false. The current position paper provides a broad perspective on scientific error, which may lead to replication failures. This broad perspective focuses on reform history and on opportunities for future reform. We organize our perspective along four main themes: institutional reform, methodological reform, statistical reform and publishing reform. For each theme, we illustrate potential errors by narrating the story of a fictional (...) researcher during the research cycle. We discuss future opportunities for reform. The resulting agenda provides a resource to usher in an era that is marked by a research culture that is less error-prone and a scientific publication landscape with fewer spurious findings. (shrink)

Robert Talisse and Scott Aikin have argued that substantive versions of value pluralism are incompatible with pragmatism, and that all such versions of pluralism must necessarily collapse into versions of strong metaphysical pluralism. They also argue that any strong version of value pluralism is incompatible with pragmatism’s meliorist commitment and will block the road of inquiry. I defend the compatibility of a version of value pluralism (the strong epistemic pluralism of John Rawls) with pragmatism, and offer counterarguments to (...) all of these claims. (shrink)

In The Libertarian Idea, Jan Narveson explains his interpretation of social contract theory this way: "The general idea of this theory is that the principles of morality are (or should be) those principles for directing everyone's conduct which it is reasonable for everyone to accept. They are the rules that everyone has good reason for wanting everyone to act on, and thus to internalize in himself or herself, and thus to reinforce in the case of everyone." It is plain, here, (...) that Narveson believes that social contract is to provide justification -- a foundation, in fact -- for 'the principles of morality'. The burden assumed in this essay is to examine how far Narveson has succeeded in making this foundational claim plausible. (shrink)

Stanislaw Lesniewski’s interests were, for the most part, more philosophical than mathematical. Prior to taking his doctorate at Jan Kazimierz University in Lvov, Lesniewski had spent time at several continental universities, apparently becoming relatively attached to the philosophy of one of his teachers, Hans Comelius, to the chapters of John Stuart Mill’s System of Logic that dealt specifically with semantics, and, in general, to studies of general grammar and philosophy of language. In these several early interests are already to (...) be found the roots of the work that was to occupy Lesniewski’s life: a search for a definitive doctrine of what sorts of things there are in the world, or better, of what language must be like if it is adequately and efficiently to represent the world. (shrink)

Benjamin Franklin's social and political thought was shaped by contacts with and knowledge of ancient aboriginal traditions. Indeed, a strong case can be made that key features of the social structure eventually outlined in the United States Constitution arose not from European sources, and not full-grown from the foreheads of European-American "founding fathers", but from aboriginal sources, communicated to the authors of the Constitution to a significant extent through Franklin. A brief sketch of the main argument to this effect is (...) offered in this essay. (shrink)

Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

In this review, we describe some of the central philosophical issues facing origins-of-life research and provide a targeted history of the developments that have led to the multidisciplinary field of origins-of-life studies. We outline these issues and developments to guide researchers and students from all fields. With respect to philosophy, we provide brief summaries of debates with respect to (1) definitions (or theories) of life, what life is and how research should be conducted in the absence of an accepted theory (...) of life, (2) the distinctions between synthetic, historical, and universal projects in origins-of-life studies, issues with strategies for inferring the origins of life, such as (3) the nature of the first living entities (the “bottom up” approach) and (4) how to infer the nature of the last universal common ancestor (the “top down” approach), and (5) the status of origins of life as a science. Each of these debates influences the others. Although there are clusters of researchers that agree on some answers to these issues, each of these debates is still open. With respect to history, we outline several independent paths that have led to some of the approaches now prevalent in origins-of-life studies. These include one path from early views of life through the scientific revolutions brought about by Linnaeus (von Linn.), Wöhler, Miller, and others. In this approach, new theories, tools, and evidence guide new thoughts about the nature of life and its origin.We also describe another family of paths motivated by a” circularity” approach to life, which is guided by such thinkers as Maturana & Varela, Gánti, Rosen, and others. These views echo ideas developed by Kant and Aristotle, though they do so using modern science in ways that produce exciting avenues of investigation. By exploring the history of these ideas, we can see how many of the issues that currently interest us have been guided by the contexts in which the ideas were developed. The disciplinary backgrounds of each of these scholars has influenced the questions they sought to answer, the experiments they envisioned, and the kinds of data they collected. We conclude by encouraging scientists and scholars in the humanities and social sciences to explore ways in which they can interact to provide a deeper understanding of the conceptual assumptions, structure, and history of origins-of-life research. This may be useful to help frame future research agendas and bring awareness to the multifaceted issues facing this challenging scientific question. (shrink)

Introduction to the Scientific Proof of the Natural Moral Law This paper proves that Aquinas has a means of demonstrating and deriving both moral goodness and the natural moral law from human nature alone. Aquinas scientifically proves the existence of the natural moral law as the natural rule of human operations from human nature alone. The distinction between moral goodness and transcendental goodness is affirmed. This provides the intellectual tools to refute the G.E. Moore (Principles of Ethics) attack against the (...) natural law as committing a "naturalistic fallacy". This article proves that instead Moore commits the fallacy of equivocation between moral goodness and transcendental goodness in his very assertion of a "naturalistic fallacy" by the proponents of the natural moral law. In the process the new deontological/kantian theory of natural law as articulated by John Finnis, Robert George, and Germain Grisez is false historically and philosophically. Ethical naturalism is affirmed as a result. (shrink)

Discerning the decisionmaking of Kim Jong-Un and the North Korean regime on issues of peaceful engagement and warlike actions endures as a mighty challenge for U.S. intelligence analysts and policymakers. In this report, we seek to inform analysis of Democratic People’s Republic of Korea (DPRK) leadership decisionmaking. To do so, we use three discussion papers that were written to facilitate discussion of an interagency working group. The three papers are assembled here in a single report. The first discussion paper describes (...) decisionmaking among different authoritarian regimes, including North Korea, and the opening up of those economies to outside engagement. The second paper outlines two different scenarios that might occur when conventional deterrence on the Korean Peninsula breaks down and the resulting decisions that North Korea’s leadership could face. The third paper assesses DPRK decisionmaking about nuclear weapon use. The report concludes with some observations, drawn from the issues covered in these three discussion papers, about DPRK decisionmaking and stability on the Korean Peninsula. (shrink)

A woman is listening to Sinatra before work. As she later describes it, ‘suddenly from nowhere I could hear my mother singing along to it … I was there again home again, hearing my mother … God knows why I should choose to remember that … then, to actually hear her and I had this image in my head … of being at home … with her singing away … like being transported back you know I got one of those (...) … like shivery feelings really suddenly’ (Anderson 2004, 9-10). An older couple, discussing their honeymoon forty years ago, each say that they can’t remember the show they saw, until through iterative, puzzled cross-cuing they finally get there – ‘Desert Song, that’s it’ (Harris et al 2011, 292). An elderly English veteran of a prisoner of war camp in Japan, finishing up morning tea with a young Japanese social scientist interested in reconciliation, suddenly calls out loudly - in Japanese - ‘stand to attention’. He stands to attention in front of her: like many of the men she interviews, he physically re-enacts fragments of that long-past world of the camp, bringing that absent past into this new present context with a visceral shock (Murakami 2001, 2012; Middleton & Brown 2005, 133-136). (shrink)

In recent years, there has been a heated debate about how to interpret findings that seem to show that humans rapidly and automatically calculate the visual perspectives of others. In the current study, we investigated the question of whether automatic interference effects found in the dot-perspective task (Samson, Apperly, Braithwaite, Andrews, & Bodley Scott, 2010) are the product of domain-specific perspective-taking processes or of domain-general “submentalizing” processes (Heyes, 2014). Previous attempts to address this question have done so by implementing (...) inanimate controls, such as arrows, as stimuli. The rationale for this is that submentalizing processes that respond to directionality should be engaged by such stimuli, whereas domain-specific perspective-taking mechanisms, if they exist, should not. These previous attempts have been limited, however, by the implied intentionality of the stimuli they have used (e.g. arrows), which may have invited participants to imbue them with perspectival agency. Drawing inspiration from “novel entity” paradigms from infant gaze-following research, we designed a version of the dot-perspective task that allowed us to precisely control whether a central stimulus was viewed as animate or inanimate. Across four experiments, we found no evidence that automatic “perspective-taking” effects in the dot-perspective task are modulated by beliefs about the animacy of the central stimulus. Our results also suggest that these effects may be due to the task-switching elements of the dot-perspective paradigm, rather than automatic directional orienting. Together, these results indicate that neither the perspective-taking nor the standard submentalizing interpretations of the dot-perspective task are fully correct. (shrink)

Mostly philosophers cause trouble. I know because on alternate Thursdays I am one -- and I live in a philosophy department where I watch all of them cause trouble. Everyone in artificial intelligence knows how much trouble philosophers can cause (and in particular, we know how much trouble one philosopher -- John Searle -- has caused). And, we know where they tend to cause it: in knowledge representation and the semantics of data structures. This essay is about a recent (...) case of this sort of thing. One of the take-home messages will be that AI ought to redouble its efforts t o understand concepts. (shrink)

A Mathematical Review by John Corcoran, SUNY/Buffalo -/- Macbeth, Danielle Diagrammatic reasoning in Frege's Begriffsschrift. Synthese 186 (2012), no. 1, 289–314. ABSTRACT This review begins with two quotations from the paper: its abstract and the first paragraph of the conclusion. The point of the quotations is to make clear by the “give-them-enough-rope” strategy how murky, incompetent, and badly written the paper is. I know I am asking a lot, but I have to ask you to read the quoted passages—aloud (...) if possible. Don’t miss the silly attempt to recycle Kant’s quip “Concepts without intuitions are empty; intuitions without concepts are blind”. What the paper was aiming at includes the absurdity: “Proofs without definitions are empty; definitions without proofs are, if not blind, then dumb.” But the author even bollixed this. The editor didn’t even notice. The copy-editor missed it. And the author’s proof-reading did not catch it. In order not to torment you I will quote the sentence as it appears: “In a slogan: proofs without definitions are empty, merely the aimless manipulation of signs according to rules; and definitions without proofs are, if no blind, then dumb.”[sic] The rest of my review discusses the paper’s astounding misattribution to contemporary logicians of the information-theoretic approach. This approach was cruelly trashed by Quine in his 1970 Philosophy of Logic, and thereafter ignored by every text I know of. The paper under review attributes generally to modern philosophers and logicians views that were never espoused by any of the prominent logicians—such as Hilbert, Gödel, Tarski, Church, and Quine—apparently in an attempt to distance them from Frege: the focus of the article. On page 310 we find the following paragraph. “In our logics it is assumed that inference potential is given by truth-conditions. Hence, we think, deduction can be nothing more than a matter of making explicit information that is already contained in one’s premises. If the deduction is valid then the information contained in the conclusion must be contained already in the premises; if that information is not contained already in the premises […], then the argument cannot be valid.” Although the paper is meticulous in citing supporting literature for less questionable points, no references are given for this. In fact, the view that deduction is the making explicit of information that is only implicit in premises has not been espoused by any standard symbolic logic books. It has only recently been articulated by a small number of philosophical logicians from a younger generation, for example, in the prize-winning essay by J. Sagüillo, Methodological practice and complementary concepts of logical consequence: Tarski’s model-theoretic consequence and Corcoran’s information-theoretic consequence, History and Philosophy of Logic, 30 (2009), pp. 21–48. The paper omits definitions of key terms including ‘ampliative’, ‘explicatory’, ‘inference potential’, ‘truth-condition’, and ‘information’. The definition of prime number on page 292 is as follows: “To say that a number is prime is to say that it is not divisible without remainder by another number”. This would make one be the only prime number. The paper being reviewed had the benefit of two anonymous referees who contributed “very helpful comments on an earlier draft”. Could these anonymous referees have read the paper? -/- J. Corcoran, U of Buffalo, SUNY -/- PS By the way, if anyone has a paper that has been turned down by other journals, any journal that would publish something like this might be worth trying. (shrink)

... The Philosophers’ Quarrel is an enjoyable tour through the salons, great cities and country retreats of the Enlightenment, in the company of some of its brightest stars. Although much of the tale turns on some tedious details of the various intrigues of Hume and Rousseau, together with their friends and collaborators, Zaretsky and Scott manage to provide their account with a number of interesting and valuable insights into the character of the thinkers involved and the social and cultural (...) life of Enlightenment Europe at this time. I particularly recommend this book to contemporary academics, who may be comforted and reassured to see that prickly, neurotic and insecure dispositions are not the invention of contemporary academic life. (shrink)

THE MIND-BODY PROBLEM: A GUIDE TO THE CURRENT DEBATE (EDITED BY RICHARD WARNER AND TA D E U S Z SZUBKA) contains recent essays by the key players in the the field of the Mind-Body problem: Searle, Fodor, Problem Honderich, Nagel, McGinn, Stich, Rorty and others. But there are a few interesting exceptions, for example Edelman, Popper, Putnam and Dennett. Nevertheless, these thinkers do get a mention here and there, and nearly all the exciting topical issues are dealt with, including (...) externalism, functionalism, intentionality, Turing computational models, and the relationship between these philosophical problems and psychology. I am particularly struck by the tendency to engage in an evasive stratagem when it comes to stating the physicalist thesis. Instead of a clear definitive position about what kind of physical science would achieve the hoped-for reduction, what I found was variations on Lewis's claim that the reduction would be effected by a "unified body of scientific theories of the sort we now accept". Materialism used to be a clear doctrine: a clockwork Universe of impenetrable particles. But materialism transcended itself. First through Hobbes' and Leibniz's criticisms of Descartes, then Newton's demolition of the Cartesian idea that matter was essentially extension by introducing gravity (action at a distance) and then through the field theories of Faraday and Maxwell, and more recently through Einstein's work, which undermined the "substance" view of matter, something that remained permanent while other changes occurred. I contrast the perspectives of the Churchlands with those of Donald T. Campbell, Karl Popper and other evolutionary and emergentist views. -/- . (shrink)

This study aimed to unveil the sentiments of college students' feedback on their teacher's teaching performance during online classes. The research utilized a qualitative approach, explicitly employing text mining. Orange software determined the most frequently used words illustrating teachers' teaching performance during online courses. Moreover, Latent Semantic Indexing (LSI) was utilized to reveal how those frequently used words were structured. Meanwhile, the study showed that the words "teacher," "class," "us," "student," "online," "teaching," "happy," "learning," "understand," and "good" were most frequently (...) used in college students' sentiments regarding their teacher's performance during online classes. The study also indicated that most students have positive feedback on their teachers' teaching performance in online courses. Therefore, the findings suggest that teachers have the abilities and knowledge to successfully impart lessons to their students despite the enormous dilemma the pandemic has brought about in every sector, especially in education. (shrink)

This paper develops a new structural psychology, and therein proposes a specific model for the scientific study of consciousness. The presented model uses Earth's geologic history of mass-extinction & recovery (evolutionary dynamics) in determining humanity’s adaptive response (conscious and non-conscious traits). It argues humanity adaptively mirrors Earth’s basic evolutionary dynamics, in a “mythologizing of natural adversity” as foundation for all human knowledge – a process that continues well into the modern era. The intellectual lineage used to develop this model includes: (...) • Evolutionary biology offers a context for this study – answering Chalmers’ “hard question,” • Paleoanthropology defines the circumstance of human emergence from Gaia, • Environmental forces on neurophysiology derive an ambiguous but instructive narrative logic (mythic sensibility), • Psychology tracks humanity’s shift from animal-self to modern creative-self, using work of Hegel > Freud > Jung > Rank > Joseph Campbell > Arnold Mindell as a new structural psychology, • Fractal geometry offers a holographic design for modeling consciousness, • Memetics presents a tool for measuring conscious traits, in a variation of the Hall-Tonna values inventory, • Finally, Structured Opportunistic Thinking, a hybrid of NTL’s T-group, and Pierce’s Power Equity Group Theory, suggests a developmental methodology. This work presents a “general hypothesizing model” of human consciousness, in attempting a science of consciousness. (shrink)

La aproximación filosófica con respecto al hombre tiene diversas metodologías, las más actuales son de índole existencial y hacen especial hincapié en el análisis fenomenológico y hermenéutico en sus distintas modalidades. Principalmente a partir del siglo XX la crítica y la minusvaloración de la metafísica como vía adecuada de conocimiento de la realidad han sido reiteradas. Sin embargo, al estudiar y conocer al hombre desde las citadas aproximaciones, hay quienes no quedan satisfechos y desean profundizar todavía más. Para ello, vuelven (...) la mirada a los autores clásicos del pensamiento antiguo, entre los que destacan Platón, Aristóteles y San Agustín. ¿Con qué se encuentran? Con la “menospreciada” metafísica, y su mayor sorpresa consiste en descubrir una serie de ideas que explican minuciosamente los distintos motivos y formas de la actuación humana. Los antiguos tenían un profundo conocimiento del hombre y sus aportaciones siguen siendo actuales. No hace falta eliminar las diferentes aproximaciones metodológicas, ya que pueden ser complementarias, y, por el contrario, plantearlas como antagónicas implicaría correr el riesgo de perder grandes y genuinos conocimientos. -/- La Antropología Metafísica es el estudio del hombre desde el punto de vista del análisis esencial del mismo. Antiguamente se la conocía con el nombre de Psicología, término que después pasó a denominar la Psicología Experimental moderna y ahora se refiere al estudio de la conducta y el comportamiento humanos. Pero originalmente, la Psicología tenía por objeto el alma, ese principio vital que mantiene la unidad de los seres vivos, en concreto, del ser humano. El estudio del alma o de la vida se puede efectuar a partir de la manifestación de sus capacidades, facultades o potencias, que a su vez se expresan mediante actos u operaciones. Y las potencias operativas no son otra cosa que capacidades que posee el hombre mediante las cuales despliega su obrar en la existencia. -/- Entre los autores clásicos medievales, destaca Tomás de Aquino, quien, en distintas obras, hace un análisis profundo del hombre. Más tarde sus seguidores y comentarista compendiaron sus trabajos en lo que se conoce como “Psicología tomista”, una psicología con ideas sorprendentes, muchas de las cuales ya habían sido preformuladas por Aristóteles. -/- Este trabajo se desarrolla bajo la perspectiva de la metafísica realista clásica desarrollada sobre todo por Aristóteles y Tomás de Aquino. Se trata de una síntesis acerca de las principales potencias operativas que intervienen en la acción humana. Se presentan de manera sucinta las tres principales potencias operativas en cuanto a su estructura y su dinámica. No se trata de una investigación exhaustiva, sino más bien de un estudio con intenciones propedéuticas, por eso se presenta en forma sintética, para que ayude a comprender a través de una aproximación general pero sistemática cómo son y actúan dichas potencias. (shrink)

Background Analysis of aphasic narratives can be a challenge for clinicians. Previous studies have mainly employed measures that categorized speech samples at the word level. They included quantification of the use and misuse of different word classes, presence and absence of narrative contents and errors, paraphasias, and perseverations, as well as morphological structures and errors within a narrative. In other words, a great amount of research has been conducted in the aphasiology literature focusing on micro-linguistic structures of oral narratives. Aspects (...) of macro- linguistic structures, such as the analysis of content information by a speaker, consistency of using cohesive devices to present information within a narrative, and order of presenting information necessary to form a coherent discourse, have not been extensively investigated. The current investigation proposes a clinical analytic system to target three aspects of macro-linguistic structures in narratives among speakers with aphasia. Specifically, (1) the presence of search events (i.e., the mentioning of key events that allow the listener to understand; Capilouto, Wright, &Wagovich, 2006) within a narrative, (2) the sequence of the mentioned events, and (3) the informativeness (i.e., the fulfillment of lexical items that allow the user to understand what the event is detailing) of the event contents, were focused in the proposed framework. Method Ten controls transcripts from were selected from the AphasiaBank (MacWhinney, Fromm, Forbes, & Holland, 2011). Three narrative tasks, including sequential picture description of ‘Refused Umbrella’, procedural narrative of making a ‘Peanut Butter and Jelly Sandwich’, and telling of ‘Cinderella’ story, were used to establish normative data for the basis of analysis. Specifically, the Search Events (e) and Informative Words (i) used by at least 70% of the speakers were listed for each genre. The sequential order of mentioning the Search Events, i.e., common order of events in 90% of the speakers, (s.total) was determined. Twelve speakers with aphasia (nine fluent and three non-fluent) were recruited and administered the Western Aphasia Battery and Object and Action Naming Battery. Their performance in the above three discourse tasks were orthographically transcribed and analyzed using the following measures: e.total, e.matched with norm, e.missed, e.irrlevant, e.extra, s.total, i.pb&j, i.umbr, i.cind, and i.total. Three samples were randomly chosen to be re-analyzed for inter- and intra-rater reliability. Results Results of an independent t-test suggested significant differences between the fluent and non-fluent subjects in sequential order of Search Events for all genres (s.total) and i.total, suggesting sensitivity of this framework to differentiate between the two fluency groups. Results of Pearson product-moment correlations revealed significant relation between Informative Words and WAB spontaneous speech scores, AQ, as well as OAB scores, for both aphasic groups. The mean value of coefficients for intra-rater reliability (0.992), with significant correlations on e.match, e.miss, and e.extra, was higher than that of inter-rater reliability (0.897). Discussion Based on our preliminary results, this objective framework allowed clinical evaluation of impairment in macro-linguistic structures present in aphasic discourse. Further extension should involve more subjects encompassing a wider range of severity with different types of aphasia. (shrink)

The work described in this report is motivated by the desire to test the expressive possibilities of action language C+. The Causal Calculator (CCalc) is a system that answers queries about action domains described in a fragment of that language. The Zoo World and the Traffic World have been proposed by Erik Sandewall in his Logic Modelling Workshop—an environment for communicating axiomatizations of action domains of nontrivial size. -/- The Zoo World consists of several cages and the exterior, gates between (...) them, and animals of several species, including humans. Actions in this domain include moving within and between cages, opening and closing gates, and mounting and riding animals. The Traffic World includes vehicles moving continuously between road crossings subject to a number of restrictions, such as speed limits and keeping a fixed safety distance away from other vehicles on the road. We show how to represent the two domains in the input language of CCalc, and how to use CCalc to test these representations. (shrink)

This paper studies the context-dependence of the first-person indexical 'I,' while attempting to make the identifiability criteria for specificity and definiteness clearer for this important indexical. Having been influenced by John Perry's work on indexicals, we'll show that this (seemingly) clearest case of an indexical poses a difficulty.

This chapter examines whether high prices for gene therapies are justified and whether the problems associated with high prices can be solved by the "pay for performance" (P4P) reimbursement model. To this end, we first describe how prices for new drugs, including gene therapies, are set in Germany (section 2.). P4P is then presented as an example of a reimbursement model (section 3.). The subsequent ethical analysis (section 4.) first examines whether P4P models can sustainably guarantee the right to health (...) and healthcare for all people (section 4.1; cf. on the "sustainable right to health" already Alex, 2021). It is then shown that cost-benefit analyses for setting prices for new gene therapies must be viewed critically from an ethical perspective and pose a problem for equity of access and thus also for the sustainable guarantee of a right to health (section 4.2). The final question is whether P4P is compatible with the idea of human dignity (Article 1 I 1 of the German Basic Law) (section 4.3; cf. already König et al., 2020). -/- Alex, K. (2021): Ethical conceptualization of a sustainable right to health(care). In: Schildmann, J. et al. (eds.): Defining the value of medical interventions. Normative and empirical challenges. Kohlhammer, Stuttgart: 29-48. PMID: 36256802 König, J. et al. (2020): Am individuellen Therapieergebnis orientierte Erstattungsverfahren in der Onkologie: ethische Implikationen am Beispiel der CAR-T-Zelltherapie. In: Ethik Med 32: 85–92. doi: 10.1007/s00481-020-00565-3. (shrink)

Abstract: In this paper, the definition of triple Aboodh transform of fractional order α, where α ϵ [0, 1], is introduced for functions which are fractional differentiable. We also present several properties of this transform. Furthermore, some main theorems and their proofs are discussed.

You can demonstrate a subjective quality like redness is different from red light. If you add a device that converts a red signal into a green one, between the retina and the optic nerve, the strawberry will seem green. It’s not about light hitting the retina, it’s about how the signal is processed. In this case, the greenness must be a quality of our conscious knowledge of the strawberry, not of the red light landing on the retina. If you use (...) sufficient, well defined terminology, you can objectively communicate the nature of subjective qualities. For example, even though you know what it is like to see something that is red you cannot know that what happens inside my brain is the same as yours. It may be that “My redness is like your greenness, both of which we call red.” The properties of the red light are the same, but the experience the light produces could be different. What we lack is a universal dictionary to define what “redness” is, and how it differs from “red”. This is because physicists can’t yet answer: “Which of all our descriptions of stuff in the brain, including possible descriptions of yet unknown processes, is a description of redness?” Consciousness isn’t a ‘hard problem’ it is a color problem. Because if you understand color, that model of computation can extend to the rest of consciousness. (shrink)

In this paper, I argue that causal theories of memory are typically committed to two independent, non-mutually entailing theses. The first thesis pertains to the necessity of appropriate causation in memory, specifying a condition token memories need to satisfy. The second pertains to the explanation of memory reliability in causal terms and it concerns memory as a type of mental state. Post-causal theories of memory can reject only the first (weak post-causalism) or both (strong post-causalism) theses. Upon this backdrop, I (...) examine Werning’s (2020) causalist argument from probabilistic correlation. I argue that it doesn’t establish the necessity of appropriate causation and thus it can only target strong post-causalist theories. I end up by presenting some general considerations, suggesting that memories may not always be causally linked to past experiences. (shrink)

SUMMARY The research focuses on the three main political parties in Albania, namely Socialist Party, Democratic Party and Socialist Movement for Integration. Its objectives are to measure the Intra-Party Democracy(IPD) in the Albanian political parties and to explore the meaning that party members attach to it. The IPD is understood and broken down into categories and sub-categories so that parties in particular and all interested actors in the field of political parties and democracy could understand, which component of IPD parties (...) are performing better and where they are performing worse. IPD is measured against two dimensions: inclusiveness and decentralization. Inclusiveness denotes the extent to which party members have the right to express their opinions and participate in the decision-making process. With decentralization is understood the process which makes possible the decentralization of the decision-making process from the highest national party level to party sub-national levels and party members. In a decentralized party, subnational party units enjoy a certain level of autonomy from the party in the center. The analysis is based on both primary and secondary data. Content analysis of party statutes particularly focuses on measuring IPD, while focus groups with party members and interviews with high-ranking officials of the political parties are used to explore the meaning that party members have on IPD, as well as validate content analysis findings. The main findings are: -/- Content Analysis of Party Statutes: Parties do have rules that govern their internal life, however these rules need to be improved in order to strengthen IPD. Especially problematic were the provisions for the role of the executive committee and party president, which provide these two institutions, especially the leader of the party with powers that don’t hold him/her accountable to the party members and middle level organs. Furthermore, members were not sufficiently involved in the procedures of candidate nominations for MPs, in the election of the national Executive and Executive Committee and in the election of the Party President. The analysis also finds that voting procedures are not sufficiently at place to allow members express their will and participate in the decision-making process and that members are not or little consulted in terms of programmatic issues. The analysis of the relationship between the national and subnational levels of party organization revealed that the center of the party has accumulated power to the detriment of the subnational units which enjoy little autonomy in the decision-making process. -/- Focus Groups and Interviews: The study finds that party members linked system-level democracy with IPD and that they have a very clear understanding if IPD: what it is and how it could be achieved. They linked IPD with the structure and organization of the party, seeing it as an important instrument that allows for decentralization of power and integration of rank and file into the decision-making process. The party members considered the statute as an important educational political tool and invoked it whenever disputes rose or decisions had to be taken. They linked IPD with the electoral system and considered that closed list proportional was a system that strengthened the power in the hands of the few at the party top executive level and weakened IPD. (shrink)

This study investigated the effectiveness of utilizing induced magnetism on the seed germination of radish (Raphanussativus) in terms of growth rate, growth speed, shoot growth, and overall development. This study utilized two groups that consisted of an experimental group where induced magnetism was present one control group where there was an absence of induced magnetism in the seed germination of Radish (Raphanus sativus). Moreover, this study aimed to determine the significant difference between the two in terms growth rate, growth speed, (...) shoot growth, and overall development. Both groups had the same amount of radish (Raphanus sativus) seeds planted in a rectangular wooden container with the same amount of measurement and soil content. This study used an experimental research design by utilizing the functions of an Electromagnetic Induction Device (EID) comprised of a 12v motor battery, light bulb, coiled wire, and switch. The EID was turned on for 10 minutes every day where the electric volts generated by the 12v motor battery were transported through the coiled wire and distributed to the metallic iron screen surrounding the area of the experimental group. The data gathered during the 12-day observation of the growth of radish (Raphanus sativus) were tabulated, analyzed, and evaluated using mean tests, standard deviation, and T-test. Based on the result and analyses of the gathered data, it was found that the experimental group, the one with the presence of induced magnetism, surpassed the control group in terms of growth speed, shoot growth, and overall seed development. However, it was also revealed that in terms of growth rate, there is no significant difference between the control group and experimental group. Therefore, the utilization of Induced Magnetism on the seed germination of radish (Raphanus sativus) is effective in terms of growth speed, shoot growth, and overall development. (shrink)

In Search of the Girl Soldiers of Aboke Abstract In a story about class, power, belonging, disappearance, and political tension, journalist Els De Temmerman tells the story of one hundred and thirty-nine girls abducted from the Aboke School in Uganda, raped, given as wives to the soldiers, and forced to kill other children. Collectively, their stories become the voice of all children abducted into heinous armies; this is a summary of their disappearance, struggle, death, and, for some, liberation. The Lord’s (...) Resistance Army is run by Joseph Kony, a man with meager education and plans to “overthrow the government in Uganda and then rule the country by the Ten Commandments” (Temmerman 15). Temmerman begins each chapter with a Scripture, such as “‘The lion has come up from the thicket, and the destroyer of the gentiles is on his way; he is gone forth from his place to make thy land desolate’” (Temmerman 1). Kony believes his twisted movement has Biblical backing, thus justifying their crimes. These Scriptures describe what is taking place throughout Uganda. Like Ocol in Ugandan Okot p’Bitek’s Song of Lawino, the LRA think they are bringing civilization, “drunk with the illusion of real power” (p’Bitek 136), cleansing the world of evil. They believe that they are God’s chosen people. This is also the story of Sister Rachele’s plea to the Pope and the rulers of nations to rescue these children. President Obama is the first U. S. President to send in American troops. In Search of the Girl Soldiers of Aboke Works Cited . (shrink)

Mainstream epistemologists don’t tend to discuss feminist epistemologies. They often don’t mention them in introductory courses or textbooks, and they almost invariably don’t take themselves to work on them. This is probably due to a suspicion that ‘feminist’ epistemologies are clouded by political motivations. In this paper I will argue two things. First, that this suspicion is misguided – a number of ‘mainstream’ epistemologists (specifically, hinge epistemologists), are in fact doing work which is entirely compatible with feminist epistemologies, and the (...) ‘extra ingredient’ required to turn a hinge epistemology into a feminist epistemology needn’t involve political motivations. And second, that bringing feminist epistemologies into the mainstream can benefit hinge epistemologies – by adding the extra ingredient which turns a hinge epistemology into a feminist epistemology, hinge epistemologists increase the motivations they can appeal to in support of their responses to scepticism. (shrink)

Desire comes in two kinds: attraction and aversion. But contemporary theories of desire have paid little attention to the distinction, and some philosophers doubt that it is psychologically real. I argue that one reason to think there is a difference between the attitudes, and to care about it, is that attractions and aversions contribute in radically different ways to our well-being. Attraction-motivated activity adds to the good life in a way that aversion-driven activity doesn’t. I argue further that the value (...) of attraction-motivated activity is irreducible to the prudential value of pleasure or desire-satisfaction. Rather it contributes in a distinctive way to the felt meaningfulness of life. In the end I offer a hypothesis: when we are attracted to something, we see it as (non-comparatively) good; and it is only when we pursue the apparent good that we see ourselves as engaged with value that makes our lives and the universe worth maintaining. -/- . (shrink)

I’m at the playground with my baby, and a smiling adult inquires, “Is it a boy or a girl?” Scientific studies show that if I say X, they will see my baby as doing A, being A, feeling A—versus if I say Y.1 They’ll likely make different assumptions about whether my baby is able to climb up the playground structures and sit without support, and they’ll encourage my baby to engage in different activities.2 And of course, they’ll respond to them (...) differently depending on whether they think the baby is a boy or a girl. What do I do if I don’t want that to happen? One way to respond to the question is not to reveal the gender, or rather, to reject the assumption that my baby already has a gender, which is arguably a weird move, breaking out of a smoothly functioning, well-oiled social exchange. Here I want to talk about this weird move: How weird it is? What are some of the reasons to make the move anyway, and what are some of the concerns? (shrink)

A 2012 review article for Metascience which explains Mach's realistic brand of empiricism, contrasting it with the common phenomenalist reading of Mach by John Blackmore in two recent books.

In this article, I aim to show how Patocˇka’s work since the 1960 s has reconceptualized the theory of intentionality. Never abandoning the referential character of the intentional relation, the Bohemian philosopher situates intentionality in its original matrix: the world. This change has the effect of moving the cause of appearing from consciousness to the world, framing it as what appears and what makes appear. Intentionality is not only connected to transcendental consciousness; intentions also must be interpreted as lines of (...) force (Kraftlinien) inside the field of appearing. Patocˇka moreover locates the origin of all intentional theory in the Aristotelian theory of the soul. Patocˇka thus wants, on the one hand, to overcome the substantialist argument that considers consciousness a permanent presence and, on the other, to move beyond an idealistic conception of consciousness. Movement is the category that allows us to express these aspects of intentionality. Inserting motion into being is a privilege unique to the soul. (shrink)

Monists and pluralists disagree concerning how many ordinary objects there are in a single situation. For instance, pluralists argue that a statue and the clay it is made of have different properties, and thereby are different. The standard monist’s response is to hold that there is just a single object, and that, under the description “being a statue”, this object is, e.g., aesthetically valuable, and that, under the description “being a piece of clay”, it is not aesthetically valuable. However, Fine (...) provided an ontological reading of the expression “an object under a description”: the theory of rigid embodiments. The debate between monists and pluralists reduplicates in the domain of ordinary occurrences, like walks and conferences. Specifically, they disagree whether an occurrence in progress (also called “process”) like John’s walk that is happening at tn is identical to some completed occurrence (also called “event”) like John’s walk that happened between, e.g., t1 and tn. Under the adoption of the pluralist’s position, the article aims to provide a novel theory of ordinary occurrences that develops the ontological reading of “under a description” to account for occurrences in progress and completed occurrences. As a first result, we formulate a theory according to which both occurrences in progress and completed occurrences are rigid embodiments. As a second result, we argue that the suggested theory is explanatorily powerful to the extent it solves two puzzles that we call “the Puzzle from the Completion of a Process” and “the Metaphysical-cum-Semantical Puzzle”. (shrink)

This paper is a commentary on the target article by Michael Arbib, “Levels of modeling of mechanisms of visually guided behavior”, in the same issue of the journal, pp. 407–465. -/- I focus on the importance of the inclusion of an ability of a system to entertain, at a given time, multiple instantiations of a given schema (situation template, frame, script, action plan, etc.), and complications introduced into neural/connectionist network systems by such inclusion.

I present a novel position vis-à-vis the views in the Latin American philosophy literature regarding whether subjects more aptly use "Hispanic" or "Latinx" to refer to Hispanic- or-Latinx people. To this end, I will argue (C) the term "Afro-Latinx" is more apt than "Hispanic" or "Latinx" in a significant number of cases. This conclusion is based on three premises. The first premise (P1) is that use of "Afro-Latinx" provides subjects with understanding of how certain events depend on anti-Black racism, US (...) society's racially unjust structure and US colonial policy. The second premise (P2) is that that neither the term "Hispanic" nor the term "Latinx" provide subjects with this understanding of how certain events depend on anti-Black racism, US society's racially unjust structure and US colonial policy. The third premise (P3) is that the term "Afro-Latinx" provides subjects with more understanding of these events than the terms, "Hispanic" and "Latinx.” I present three cases which feature the experiences of Afro-Dominican people. The 1992 murder of Dominican man Kiko García by New York Police officer O’Keefe is first case. The second case is the Washington Heights Uprising that ensued Kiko García’ murder. An instance where a nightclub bouncer in the Dominican Republic denies a Dominican women entry because of her hair texture composes the third case. (shrink)

I argue racial injustice undermines the reliability of news source reports in the information domain of racial injustice. I argue that this in turn undermines subjects’ doxastic justification in inferences they base on these news sources in the racial injustice information domain. I explain that racial injustice does this undermining through the effect of racial prejudice on news organizations’ members and the effect of society's racially unjust structure on non-dominant racial group-controlled news sources.

Bernard Linsky and Edward Zalta have recently proposed a new form of actualism. I characterize the general form of their view and the motivations behind it. I argue that it is not quite new – it bears interesting similarities to Alvin Plantinga’s view – and that it definitely isn’t actualist.

This study was conducted to determine the effectiveness of utilizing the Dual-axis Solar Tracker in harnessing solar energy and storing it in lithium-ion batteries in terms of voltage and milliamps per hour gained. This study utilized two solar panel systems, the Static Solar Panel System and the Dual-Axis Solar Tracker and aimed to prove the significant difference generated by solar panel systems in terms of voltage and milliamps per hour. This study employed an Applied Experimental Research Design utilizing Arduino Uno, (...) light-dependent resistors, micro servos, and solar panels to create the Dual-Axis Solar Tracker. The data gathered from the electric quantities during the seven-day sun exposure were tabulated, analyzed, and computed using mean tests, standard deviation, and T-tests to find the significant difference between the two solar panels. Based on the analyses of the data, it was revealed that the Dual-Axis Solar Tracker was superior in terms of voltage and milliamps per hour generated compared to the Static Solar Panel System. Moreover, computations using the T-test found that in terms of voltage and milliamps per hour generated, there was a significant difference between the Dual-Axis Solar Tracker and the Static Solar Panel System. Based on the findings of the study, it is concluded that the utilization of the Dual-Axis Solar Tracker statistically increases the effectiveness of solar panels in harnessing energy generation. (shrink)

In assessing the veridicality of utterances, we normally seem to assess the satisfaction of conditions that the speaker had been concerned to get right in making the utterance. However, the debate about assessor-relativism about epistemic modals, predicates of taste, gradable adjectives and conditionals has been largely driven by cases in which seemingly felicitous assessments of utterances are insensitive to aspects of the context of utterance that were highly relevant to the speaker’s choice of words. In this paper, we offer an (...) explanation of why certain locutions invite insensitive assessments, focusing primarily on ’tasty’ and ’might’. We spell out some reasons why felicitous insensitive assessments are puzzling and argue briefly that recent attempts to accommodate such assessments (including attempts by John MacFarlane, Kai von Fintel and Anthony Gillies) all fail to provide more than hints at a solution to the puzzle. In the main part of the paper, we develop an account of felicitous insensitive assessments by identifying a number of pragmatic factors that influence the felicity of assessments. Before closing, we argue that the role of these factors extend beyond cases considered in the debate about assessor-relativism and fit comfortably with standard contextualist analyses of the relevant locutions. (shrink)

Mental (or semantic) holism is the doctrine that the identity of a belief content (or the meaning of a sentence that expresses it) is determined by its place in the web of beliefs or sentences comprising a whole theory or group of theories. It can be contrasted with two other views: atomism and molecularism. Molecularism characterizes meaning and content in terms of relatively small parts of the web in a way that allows many different theories to share those parts. For (...) example, the meaning of 'chase' might be said by a molecularist to be try to catch. Atomism characterizes meaning and content in terms of none of the web; it says that sentences and beliefs have meaning or content independently of their relations to other sentences or beliefs. One major motivation for holism has come from reflections on the natures of confirmation and learning. As Quine (1953) observed, claims about the world are confirmed not individually, but only in conjunction with theories of which they are a part. And typically, one cannot come to understand scientific claims without understanding a significant chunk of the theory of which they are a part. For example, in learning the Newtonian concepts of 'force', 'mass', kinetic energy' and 'momentum', one doesn't learn any definitions of these terms in terms that are understood beforehand, for there are no such definitions. Rather, these theoretical terms were all learned together in conjunction with procedures for solving problems. The major problem with holism is that it threatens to make generalization in psychology virtually impossible. If the content of any state depends on all others, it would be extremely unlikely that any two believers would ever share a state with the same content. Moreover, holism would appear to conflict with our ordinary conception of reasoning. What sentences one accepts influence what one infers. if i accept a sentence and then later reject it, i thereby change the inferential role of that sentence, so the meaning of what i accept wouldn't be the same as what i later reject. but then it would be difficult to understand on this view how one could rationally --or even irrationally!-- change one's mind. and agreement and translation are also problematic for much the same reason. holists have responded (1) by proposing that we should think not in terms of "same/different" meaning but in terms of a gradient of similarity of meaning, (2) by proposing "two factor" theories or (3) by simply accepting the consequence that there is no real difference between changing meanings and changing beliefs. (shrink)

I sometimes hear the statement that good has no chance in the battle against evil. People often say “ You won’t change the world anyway” or “That’s what the system looks like”. In fact, some arguments are irresistible, but only in certain circumstances. However, when these circumstances do not occur, and they do not occur very often, it turns out that good has very strong tactics. When you apply it, then it is simply irresistible. What kind of tactics is it? (...) Is it worth using it? Is it worth being a moral person? Sometimes it seems that our evil actions won’t result in any negative consequences. However, evil provides services and demands profits in return. Thus, it is very selfish. How did we pay since we didn’t spend any penny? On the contrary, we even earned something. Isn’t it puzzling? This “profit” is an extremely mysterious phenomenon, yet very real. Therefore, I examined various situations that happened in life and enclosed my major observations in this book. I hope it won’t be only a fascinating reading but above all an abundant source of inspiration for everyone who seeks to understand a deeper sense of the surrounding world. (shrink)

Metaphysics-first approaches dominate the current literature in the epistemology of modality. According to metaphysics-firsters, metaphysical theses have an important role in the justification of modal epistemologies. For example, the thesis that essentialist truths constitute the metaphysical grounds of modal truths is meant to have an important role in the justification of essentialist modal epistemologies. In this article, we argue against this approach. We first pick up some of the groundwork on behalf of the metaphysics-firsters and explicitly spell out potential arguments (...) for their view. However, despite some initial plausibility, these arguments are ultimately found wanting. We conclude that the metaphysics-first approach lacks motivation and puts far too stringent demands upon modal epistemologists. (shrink)

Most descriptions of higher-order vagueness in terms of traditional modal logic generate so-called higher-order vagueness paradoxes. The one that doesn't is problematic otherwise. Consequently, the present trend is toward more complex, non-standard theories. However, there is no need for this.In this paper I introduce a theory of higher-order vagueness that is paradox-free and can be expressed in the first-order extension of a normal modal system that is complete with respect to single-domain Kripke-frame semantics. This is the system QS4M+BF+FIN. It corresponds (...) to the class of transitive, reflexive and final frames. With borderlineness defined logically as usual, it then follows that something is borderline precisely when it is higher-order borderline, and that a predicate is vague precisely when it is higher-order vague.Like Williamson's, the theory proposed here has no clear borderline cases in Sorites sequences. I argue that objections that there must be clear borderline cases ensue from the confusion of two notions of borderlineness—one associated with genuine higher-order vagueness, the other employed to sort objects into categories—and that the higher-order vagueness paradoxes result from superimposing the second notion onto the first. Lastly, I address some further potential objections. (shrink)

This essay traces the development of the philosophical debates concerning active powers and human agency in eighteenth-century Scotland. I examine how and why Scottish philosophers such as Francis Hutcheson, George Turnbull, David Hume, and Henry Home, Lord Kames, depart from John Locke’s and other traditional conceptions of the will and how Thomas Reid and Dugald Stewart reinstate Locke’s distinction between volition and desire. Moreover, I examine what role desires, passions, and motives play in the writings of these and other (...) Scottish Enlightenment philosophers on human agency and draw attention to their underlying disputes concerning liberty and necessity. I end by reflecting on how classifications of principles of actions changed in eighteenth and early nineteenth-century Scottish philosophy. (shrink)

My chapter examines Isaac Watts’s and Catharine Trotter Cockburn’s views concerning the metaphysics of the mind and their underlying accounts of powers and substances. In Philosophical Essays on Various Subjects Watts criticizes Locke’s account of substances and argues for his own preferred account of substance. Watts argues that there is no need to postulate an unknown substratum, as Locke does. Instead, Watts searches for a better explanation of what substances are. His proposal is that bodily substance just is solid extension (...) and that mental substance is identical with the power of thinking. This means that Watts believes that some powers can be substances. I will show how Watts defends his account of substances against various objections. Cockburn was not satisfied by Watts’s account of substance and disagrees with Watts’s understanding of powers. She believes that Watts is too quick to draw metaphysical conclusions. Cockburn takes seriously the limitations of human understanding and emphasizes that humans are ignorant about many metaphysical truths. I end by assessing the strengths and weaknesses of Watts’s and Cockburn’s accounts of powers and substances. (shrink)

Hume’s theory of personal identity is developed in response to Locke’s account of personal identity. Yet it is striking that Hume does not emphasize Locke’s distinction between persons and human beings. It seems even more striking that Hume’s account of the self in Books 2 and 3 of the Treatise has less scope for distinguishing persons from human beings than his account in Book 1. This is puzzling, because Locke originally introduced the distinction in order to answer questions of moral (...) accountability and Hume’s discussion of the self in Book 2 provides the foundation of his moral theory in Book 3. In response to the puzzle I show that Locke and Hume hold different moral and religious views and these differences are important to explain why their theories of personal identity differ. (shrink)

William Molyneux (1656–1698) was an Irish experimental philosopher and politician, who played a major role in the intellectual life in seventeenth-century Dublin. He became Locke’s friend and correspondent in 1692 and was probably Locke’s philosophically most significant correspondent. Locke approached Molyneux for advice for revising his Essay concerning Human Understanding as he was preparing the second and subsequent editions. Locke made several changes in response to Molyneux’s suggestions; they include major revisions of the chapter ‘Of Power’ (2.21), the addition of (...) the chapter ‘Of Identity and Diversity’ (2.27), and the addition of the so-called Molyneux Problem (2.9.8). Molyneux repeatedly requested that Locke develops his views on morality. Additionally, their correspondence turned to questions concerning education and Molyneux’s keen interest in the topic likely prompted Locke to publish Some Thoughts Concerning Education in 1693. Moreover, Molyneux drew on Locke’s anonymously published Two Treatises of Government in his The Case of Ireland’s Being Bound by Acts of Parliament in England, Stated, which was first published in the spring of 1698. Molyneux revealed Locke’s authorship of Two Treatises against Locke’s will, yet their friendship continued until Molyneux’s untimely death in October 1698. (shrink)