This paper examines how a person’s life may be shaped by living with a sense of the mystery of reality. What virtues, if any, are encouraged by such a sense? The first section rehearses a radical ”doctrine of mystery’, according to which reality as it anyway is, independently of human perspectives, is ineffable. It is then argued that a sense of mystery may provide ”measure’ for human lives. For it is possible for a life to be ”consonant’ with this sense (...) -- through exercising humility, for example -- and even to emulate mystery. A further section corrects a misunderstanding about the connection between a sense of mystery and the virtues it invites, while a final section considers the relationship between living with mystery and religious faith. (shrink)

A study is reported testing two hypotheses about a close parallel relation between indicative conditionals, if A then B , and conditional bets, I bet you that if A then B . The first is that both the indicative conditional and the conditional bet are related to the conditional probability, P(B|A). The second is that de Finetti's three-valued truth table has psychological reality for both types of conditional— true , false , or void for indicative conditionals and win , lose (...) , or void for conditional bets. The participants were presented with an array of chips in two different colours and two different shapes, and an indicative conditional or a conditional bet about a random chip. They had to make judgements in two conditions: either about the chances of making the indicative conditional true or false or about the chances of winning or losing the conditional bet. The observed distributions of responses in the two conditions were generally related to the conditional probability, supporting the first hypothesis. In addition, a majority of participants in further conditions chose the third option, “void”, when the antecedent of the conditional was false, supporting the second hypothesis. (shrink)

● Any given placement (e.g. Sun in Taurus; Mars in Capricorn; Mercury in the third house) is necessarily common to tens of thousands of people. Saturn in the ninth house, for example, will not behave the same or produce the same effects in the twenty or one hundred charts in which we find it there. In each case Saturn will behave in accordance with the rest of the astrographic/chart composition (as if we stayed in the same hotel in different epochs (...) or different people contracted the same disease; our stay will be different each time, according to the epoch, and each person’s symptoms will too, be different, according to their individual biochemistry; not to mention that each chart or astrography, like each genetic code or sequence, is unrepeatable). Certainly, “no planet can produce, on its own, what only the combined or concerted action of all can” (BUSTAMANTE, 2023, SPICA magazine, pp. 93-111). Hence the synergistic nature of the interpretative exercise (i.e., the whole is greater than all its parts). The fundamental component of the mathematical expression of the interpretive exercise is: astrological triangulation, the functional denomination for what we know as synthesis (WEISS, 1946; LEO, 1983, HAND, 1981). In order to demonstrate its usefulness, as well as the convenience of its mathematical expression, we have chosen two individuals (JEFFREY DAHMER, STEVEN SPIELBERG) whose astrographies do not—according to the community—explain their lives. The rest of the astrographies correspond to those of serial killers JOHN WAYNE GACY, DAVID CARPENTER, and TED BUNDY. ● We explain, by means of algebraic notations, the synthesis and the functional values that make up the synthesis. ● We take the Moon and Neptune as relevant bodies for the purpose of diagnosing or studying endocrine or neurohormonal issues, and Mars, Pluto, and Saturn as relevant planets for the purpose of inferring violence or sinister behaviour, upon the case, and quadratures or oppositions—and conjunctions—between Venus and the Moon, the Moon and Neptune, and the Sun or Venus and Neptune or Uranus as indicators of neurohormonal disorders and/or sexual deviance (APA definition) . ● We consider quadratures (90º) or oppositions (180º)—and conjunctions—between Mercury or the Moon and Saturn, or between Mars or the Moon and Saturn, Uranus, Neptune, and/or Pluto as powerful indications of violence or mental disorders, upon the case. ● We have also regarded Sagittarius as a sign as expansive and abundant as its ruler, Jupiter, according to the best of its characterisations (or as an exceptionally swift and wild sign, according to other characterisations), and the fifth region of a natal chart as one closely related to fortune in a broad sense (material and immaterial). ● Because we advocate the idea that orbs should be predicated of the planet (size, speed), not the aspect itself, the gas giants (Jupiter, Saturn, Uranus, and Neptune) and the Sun have been granted up to 10º of orb (or 12º, in the case of broad influence ). We understand aspectual relationships as angular relationships held between two or more celestial bodies placed in signs with at least one property in common (according to our molecular theory of the ecliptic, compatible with the optical theory of the aspects from the Hellenistic tradition). (shrink)

● Un emplazamiento cualquiera (v. gr. sol en Tauro; Marte en Capricornio; Mercurio en la tercera casa) es necesariamente común a decenas de miles de personas. Saturno hospedado en la novena casa, por ejemplo, no se comportará de la misma manera o no producirá los mismos efectos en las veinte o cien cartas en que allí lo encontremos, sino en concordancia con el resto de la composición astrográfica (como hospedarnos en el mismo hotel en diferentes épocas o diferentes personas haber (...) contraído la misma enfermedad; nuestra estadía será diferente cada vez, según la época, y no todos los enfermos presentarán los mismos síntomas, según su metabolismo; por no mencionar que cada astrografía, como cada código o secuencia genética, es irrepetible). Ciertamente, “ningún planeta puede, por sí solo, producir lo que solamente la acción mancomunada o conjunta de todos puede” (BUSTAMANTE, 2023, revista SPICA, págs. 93-111). He aquí la naturaleza o condición sinérgica del ejercicio interpretativo (i.e., el todo es poco más que la suma de todas sus partes). ● El componente fundamental de la expresión matemática del ejercicio interpretativo lo constituye la triangulación astrológica, denominación funcional de lo que conocemos como síntesis (WEISS, 1946; LEO, 1983; HAND, 1981). ● Con el fin de demostrar su utilidad, así como la conveniencia de su expresión matemática, hemos escogido dos individuos (JEFFREY DAHMER, STEVEN SPIELBERG) cuyas astrografías no explican, según la comunidad, sus vidas. El resto de las astrografías corresponden a las de los asesinos en serie JOHN WAYNE GACY, DAVID CARPENTER y TED BUNDY. ● A través de notaciones algebraicas, explicamos la síntesis y los valores funcionales que la componen. ● Tomamos la luna y Neptuno como planetas relevantes a propósito del diagnóstico o el estudio de asuntos endocrinos o neurohormonales y a Marte, Plutón y Saturno como planetas relevantes a los fines de inferir violencia o comportamiento siniestro, según el caso, y las cuadraturas u oposiciones —y conjunciones— entre Venus y la luna, la luna y Neptuno o entre el sol o Venus y Neptuno o Urano como indicadores de desórdenes neurohormonales y/o de desviación sexual (definición APA) . ● Consideramos las cuadraturas u oposiciones —y conjunciones— entre: Mercurio o la luna y Saturno, o entre Marte o la luna y Saturno, Urano, Neptuno y/o Plutón como poderosos indicios de violencia o de desequilibrio, según el caso. ● También hemos considerado a Sagitario como un signo tan expansivo y abundante como su regente, Júpiter, según la mejor de sus caracterizaciones (o excepcionalmente raudo y salvaje, según otras), y a la quinta región de un mapa natal como una estrechamente relacionada con la fortuna en sentido amplio (material e inmaterial). ● Debido a que defendemos la idea según la cual los orbes deben predicarse del planeta (tamaño, velocidad), no del aspecto, a los gigantes gaseosos (Júpiter, Saturno, Urano y Neptuno) y al sol les hemos concedido hasta 10º de orbe (o 12º, en el caso de la influencia amplia ). ● Entendemos las relaciones aspectuales como relaciones angulares sostenidas entre dos o más cuerpos celestes emplazados en signos con al menos una propiedad en común (según nuestra teoría molecular de la eclíptica, compatible con la teoría óptica de los aspectos de la tradición helenística). (shrink)

● Este ensayo corre el velo de una estrecha relación entre los símbolos astrológicos y el mundo fenoménico y explica cómo dicotomías características de los siglos XVIII y XX han dificultado esta y otras comprensiones de nuestra realidad. ● Las observaciones se apoyan en los hallazgos producidos durante los últimos cuarenta años con relación a los planetas, sus características astronómicas y propiedades astrofísicas, hallazgos que corroboran casi integralmente los esbozos que sobre los planetas hiciera, entre otros autores, VETIO VALENTE (s. (...) II a.C.) en su afamada Antología. ● Como el sol alcanza su mayor fuerza durante el verano y su menor fuerza durante el invierno, también el resto de los miembros de nuestro sistema solar cobran fuerzas en diferentes segmentos de la eclíptica, contribuyendo en matices específicos de las condiciones del clima en diferentes épocas, lo que nutre las significaciones (o propiedades) zodiacales. ● Apoyándonos en hechos constatados por la física y el magnetismo molecular, defendemos la eclíptica (Zodiaco) como una realidad físico química cuyos doce segmentos afianzan o menoscaban el poder aparentemente electromagnético de algunos planetas con relación a la Tierra en diferentes épocas según la revolución solar de cada uno. ● Con el fin de favorecer la comprensión, prejuicios comunes necesitan ser tratados, y de ahí los tres acápites que componen la introducción del ensayo, uno de los cuales aborda un recurso del lenguaje, la alegoría, con el fin de demostrar su recurrente necesidad tanto en el pasado como en el presente sin que dicha práctica constituya una infidelidad fenoménica. ● Por último, ofrecemos la explicación más plausible producida hasta ahora sobre el mecanismo de acción responsable de la astrología, es decir, de la influencia de los cuerpos celestes (más allá de la luna y del sol) sobre la vida en la Tierra: «quantum entanglement», o la “acción misteriosa a distancia” incrédulamente formulada por EINSTEIN en 1935, cuya comprobación les ganó el Premio Nobel de Física 2022 a ANTON ZEILINGER y JOHN CLAUSER. ● Utilizamos un número considerable de ilustraciones a los fines de apoyar la comprensión del lector, que puede no ser astrólogo sino un curioso, y esperamos que sean más los curiosos que los astrólogos, especialmente si hacen parte de la comunidad científica. (shrink)

In Beyond Physicalism, an interdisciplinary group of physical scientists, behavioral and social scientists, and humanists from the Esalen Institute’s Center for Theory and Research argue that physicalism must be replaced by an expanded scientific naturalism that accommodates something spiritual at the heart of nature.

Do psychological traits predict philosophical views? We administered the PhilPapers Survey, created by David Bourget and David Chalmers, which consists of 30 views on central philosophical topics (e.g., epistemology, ethics, metaphysics, philosophy of mind, and philosophy of language) to a sample of professional philosophers (N = 314). We extended the PhilPapers survey to measure a number of psychological traits, such as personality, numeracy, well-being, lifestyle, and life experiences. We also included non-technical ‘translations’ of these views for eventual use (...) in other populations. We found limited to no support for the notion that personality or demographics predict philosophical views. We did, however, find that some psychological traits were predictive of philosophical views, even after strict correction for multiple comparisons. Findings include: higher interest in numeracy predicted physicalism, naturalism, and consequentialism; lower levels of well-being and higher levels of mental illness predicted hard determinism; using substances such as psychedelics and marijuana predicted non-realist and subjectivist views of morality and aesthetics; having had a transformative or self-transcendent experience predicted theism and idealism. We discuss whether or not these empirical results have philosophical implications, while noting that 68% of our sample of professional philosophers indicated that such findings would indeed have philosophical value. (shrink)

For many years there has been a debate about the role of the parietal lobe in the generation of behavior. Does it generate movement plans (intention) or choose objects in the environment for further processing? To answer this, we focus on the lateral intraparietal area (LIP), an area that has been shown to play independent roles in target selection for saccades and the generation of visual attention. Based on results from a variety of tasks, we propose that LIP acts as (...) a priority map in which objects are represented by activity proportional to their behavioral priority. We present evidence to show that the priority map combines bottom-up inputs like a rapid visual response with an array of top-down signals like a saccade plan. The spatial location representing the peak of the map is used by the oculomotor system to target saccades and by the visual system to guide visual attention. (shrink)

In the remainder of this article, we will disarm an important motivation for epistemic contextualism and interest-relative invariantism. We will accomplish this by presenting a stringent test of whether there is a stakes effect on ordinary knowledge ascription. Having shown that, even on a stringent way of testing, stakes fail to impact ordinary knowledge ascription, we will conclude that we should take another look at classical invariantism. Here is how we will proceed. Section 1 lays out some limitations of previous (...) research on stakes. Section 2 presents our study and concludes that there is little evidence for a substantial stakes effect. Section 3 responds to objections. The conclusion clears the way for classical invariantism. (shrink)

Machine learning algorithms may radically improve our ability to diagnose and treat disease. For moral, legal, and scientific reasons, it is essential that doctors and patients be able to understand and explain the predictions of these models. Scalable, customisable, and ethical solutions can be achieved by working together with relevant stakeholders, including patients, data scientists, and policy makers.

Is behavioral integration (i.e., which occurs when a subjects assertion that p matches her non-verbal behavior) a necessary feature of belief in folk psychology? Our data from nearly 6,000 people across twenty-six samples, spanning twenty-two countries suggests that it is not. Given the surprising cross-cultural robustness of our findings, we suggest that the types of evidence for the ascription of a belief are, at least in some circumstances, lexicographically ordered: assertions are first taken into account, and when an agent sincerely (...) asserts that p, non-linguistic behavioral evidence is disregarded. In light of this, we take ourselves to have discovered a universal principle governing the ascription of beliefs in folk psychology. (shrink)

Does the Ship of Theseus present a genuine puzzle about persistence due to conflicting intuitions based on “continuity of form” and “continuity of matter” pulling in opposite directions? Philosophers are divided. Some claim that it presents a genuine puzzle but disagree over whether there is a solution. Others claim that there is no puzzle at all since the case has an obvious solution. To assess these proposals, we conducted a cross-cultural study involving nearly 3,000 people across twenty-two countries, speaking eighteen (...) different languages. Our results speak against the proposal that there is no puzzle at all and against the proposal that there is a puzzle but one that has no solution. Our results suggest that there are two criteria—“continuity of form” and “continuity of matter”— that constitute our concept of persistence and these two criteria receive different weightings in settling matters concerning persistence. (shrink)

Some types of solar radiation management (SRM) research are ethically problematic because they expose persons, animals, and ecosystems to significant risks. In our earlier work, we argued for ethical norms for SRM research based on norms for biomedical research. Biomedical researchers may not conduct research on persons without their consent, but universal consent is impractical for SRM research. We argue that instead of requiring universal consent, ethical norms for SRM research require only political legitimacy in decision-making about global SRM trials. (...) Using Allen Buchanan & Robert Keohane's model of global political legitimacy, we examine several existing global institutions as possible analogues for a politically legitimate SRM decision-making body. (shrink)

This chapter discusses the Ganser syndrome and gives a brief account on its clinical features. A significant number of clinicians in Europe continued accepting Ganser's basic postulates that the patients showed significant memory disorder and 'answers towards the question' within the framework of traumatic or reactive hysteria. In elderly patients, Ganser type symptoms may be indicative of the onset of dementia. Ganser syndrome raises the question of the interaction between concepts, ideology and clinical observation. The clinician must be aware that (...) a misdiagnosed case of Ganser-type hysteria may result in lawsuits, unnecessary surgical interventions, inappropriate use of minor and major tranquillizers, and social consequences that may be destabilizing for the patient and family. Positive results in the organic investigation should lead to a firm diagnosis and disconfirmation of Ganser syndrome. Persistent negative results and dramatic improvement should tend to confirm the diagnosis. (shrink)

Learn the business language you need to feel confident in taking the first steps toward becoming successful business majors and successful business people with Boone and Kurtz's best-selling CONTEMPORARY BUSINESS and its accompanying Audio CD-ROM. You'll find all the most important introductory business topics, using the most current and interesting examples happening right now in the business world! With this textbook, you'll hone skills that will make you more successful as students and employees.

Significant associations have been found between specific human leukocyte antigen (HLA) alleles and organ transplant rejection, autoimmune disease development, and the response to infection. Traditional searches for disease associations have conventionally measured risk associated with the presence of individual HLA alleles. However, given the high level of HLA polymorphism, the pattern of amino acid variability, and the fact that most of the HLA variation occurs at functionally important sites, it may be that a combination of variable amino acid sites shared (...) by several alleles (shared epitopes) are better descriptors of the actual causative genetic variants. Here we describe a novel approach to genetic association analysis in which genes/proteins are broken down into smaller sequence features and then variant types defined for each feature, allowing for independent analysis of disease association with each sequence feature variant type. We have used this approach to analyze a cohort of systemic sclerosis patients and show that a sequence feature composed of specific amino acid residues in peptide binding pockets 4 and 7 of HLA-DRB1 explains much of the molecular determinant of risk for systemic sclerosis. (shrink)

One of the most expected properties of a logical system is that it can be algebraizable, in the sense that an algebraic counterpart of the deductive machinery could be found. Since the inception of da Costa's paraconsistent calculi, an algebraic equivalent for such systems have been searched. It is known that these systems are non self-extensional (i.e., they do not satisfy the replacement property). More than this, they are not algebraizable in the sense of Blok-Pigozzi. The same negative results hold (...) for several systems of the hierarchy of paraconsistent logics known as Logics of Formal Inconsistency (LFIs). Because of this, these logics are uniquely characterized by semantics of non-deterministic kind. This paper offers a solution for two open problems in the domain of paraconsistency, in particular connected to algebraization of LFIs, by obtaining several LFIs weaker than C1, each of one is algebraizable in the standard Lindenbaum-Tarski's sense by a suitable variety of Boolean algebras extended with operators. This means that such LFIs satisfy the replacement property. The weakest LFI satisfying replacement presented here is called RmbC, which is obtained from the basic LFI called mbC. Some axiomatic extensions of RmbC are also studied, and in addition a neighborhood semantics is defined for such systems. It is shown that RmbC can be defined within the minimal bimodal non-normal logic E+E defined by the fusion of the non-normal modal logic E with itself. Finally, the framework is extended to first-order languages. RQmbC, the quantified extension of RmbC, is shown to be sound and complete w.r.t. BALFI semantics. (shrink)

Graduates' employability indicates the excellent education and relevant preparation they obtained from their respective degrees. Tracer studies have enabled higher education institutions to profile their graduates while also reflecting on the quality of education they provide. With the foregoing, a tracer study determined the demographic and academic profile of teacher education graduates from 2017 to 2020 in a state university in the West Philippines. It also ascertained the advanced studies they attended after college, their employment data, the relevance of college (...) preparation with their current employment, difficulties they encountered while securing employment and in their present job, and recommendations to strengthen the teacher education program. The study utilized a descriptive survey research design with 80 non-random samples chosen based on availability. The survey was based on the Philippine Commission on Higher Education with modifications elucidated from previous studies. Results showed that graduates took the teacher education program with a strong passion for the teaching profession. More graduates received honors and awards, passed the licensure examinations for teachers, attended advanced studies for professional development, and are employable. Besides, the graduates’ college preparation is relevant to their current employment. Further, difficulties and problems encountered and recommendations to strengthen the teacher education program were noted. These findings may serve as a baseline for curriculum review and give suggestions for future tracer studies. (shrink)

Ontology is one strategy for promoting interoperability of heterogeneous data through consistent tagging. An ontology is a controlled structured vocabulary consisting of general terms (such as “cell” or “image” or “tissue” or “microscope”) that form the basis for such tagging. These terms are designed to represent the types of entities in the domain of reality that the ontology has been devised to capture; the terms are provided with logical defi nitions thereby also supporting reasoning over the tagged data. Aim: This (...) paper provides a survey of the biomedical imaging ontologies that have been developed thus far. It outlines the challenges, particularly faced by ontologies in the fields of histopathological imaging and image analysis, and suggests a strategy for addressing these challenges in the example domain of quantitative histopathology imaging. The ultimate goal is to support the multiscale understanding of disease that comes from using interoperable ontologies to integrate imaging data with clinical and genomics data. (shrink)

A representationalist-friendly introduction to representationalism which covers a number of central problems and objections.

If death is a harm then it is a harm that cannot be experienced. The proponent of death's harm must therefore provide an answer to Epicurus, when he says that ‘death, is nothing to us, since when we are, death is not present, and when death is present, then we are not’. In this paper I respond to the two main ways philosophers have attempted to answer Epicurus, regarding the subject of death's harm: either directly or via analogy. The direct (...) way argues that there is a truth-maker (or difference-maker) for death's harm, namely in virtue of the intrinsic value the subject's life would have had if they had not died. The analogy argues that there are cases analogous to death, where the subject is harmed although they experience no pain as a result. I argue that both accounts beg the question against the Epicurean: the first by presupposing that one can be harmed while experiencing no displeasure as a result and the second by conflating a de re with a de dicto reading of death's harm. Thus, I argue, until better arguments are provided, one is best to agree with Epicurus and those who follow him that death is not a harm. (shrink)

In her book Specifications Grading, Linda B. Nilson advocates for a grading regimen she claims will save faculty time, increase student motivation, and improve the quality and rigor of student work. If she is right, there is a strong case for many faculty to adopt some version of the system she recommends. In this paper, we argue that she is mostly right and recommend that faculty move away from traditional grading. We begin by rehearsing the central features of specifications grading (...) and providing two examples of how to implement it in philosophy classes. In light of the examples, we argue that specifications grading fulfills two of Nilson’s central desiderata but not the third. Since specifications grading generates two benefits that when combined increase student learning, without adding or increasing burdens, we conclude that student learning increases when courses are revised to include aspects of specifications grading. (shrink)

Under the assumptions of the standard Condorcet Jury Theorem, majority verdicts are virtually certain to be correct if the competence of voters is greater than one-half, and virtually certain to be incorrect if voter competence is less than one-half. But which is the case? Here we turn the Jury Theorem on its head, to provide one way of addressing that question. The same logic implies that, if the outcome saw 60 percent of voters supporting one proposition and 40 percent the (...) other, then average voter competence must either be 0.60 or 0.40. We still have to decide which, but limiting the choice to those two values is a considerable aid in that. Key Words: Condorcet Jury Theorem • epistemic democracy • voter competence. (shrink)

Chapter 20 David Kovacs’ “Essence, Grounding, and Explanation” sets out four different ways in which essence might be taken to relate to the notion of grounding or metaphysical explanation, i.e., the type of connection that is often expressed by means of non-causal “in virtue of” or “because”-claims: (i) Unity: essence and grounding belong to a unified set of explanatory concepts; (ii) Supplementation: essence and grounding both contribute in their own way to a distinctive type of explanation; (iii) Independence: essence (...) is a sui generis notion with no straightforward conceptual links to grounding; and (iv) Irrelevance: essence is not an explanatory notion at all and therefore should not be viewed as connected to explanatory notions like grounding. As Kovacs brings out in the chapter, a wide variety of attitudes are represented in the literature even among philosophers who are sympathetic to the recent “hyperintensional” turn in metaphysics when it comes to the question of how the notions of essence and grounding interact with one another. (shrink)

Recent years have seen a surge in online collaboration between experts and amateurs on scientific research. In this article, we analyse the epistemological implications of these crowdsourced projects, with a focus on Zooniverse, the world’s largest citizen science web portal. We use quantitative methods to evaluate the platform’s success in producing large volumes of observation statements and high impact scientific discoveries relative to more conventional means of data processing. Through empirical evidence, Bayesian reasoning, and conceptual analysis, we show how information (...) and communication technologies enhance the reliability, scalability, and connectivity of crowdsourced e-research, giving online citizen science projects powerful epistemic advantages over more traditional modes of scientific investigation. These results highlight the essential role played by technologically mediated social interaction in contemporary knowledge production. We conclude by calling for an explicitly sociotechnical turn in the philosophy of science that combines insights from statistics and logic to analyse the latest developments in scientific research. (shrink)

This article examines whether people share the Gettier intuition (viz. that someone who has a true justified belief that p may nonetheless fail to know that p) in 24 sites, located in 23 countries (counting Hong-Kong as a distinct country) and across 17 languages. We also consider the possible influence of gender and personality on this intuition with a very large sample size. Finally, we examine whether the Gettier intuition varies across people as a function of their disposition to engage (...) in “reflective” thinking. (shrink)

The purpose of this paper is to review and discuss Luciano Floridi’s 2019 book The Logic of Information: A Theory of Philosophy as Conceptual Design, the latest instalment in his philosophy of information (PI) tetralogy, particularly with respect to its implications for library and information studies (LIS) .

This essay aims to vindicate the thesis that cognitive computational properties are abstract objects implemented in physical systems. I avail of Voevodsky's Univalence Axiom and function type equivalence in Homotopy Type Theory, in order to specify an abstraction principle for epistemic (hyper-)intensions. The homotopic abstraction principle for epistemic (hyper-)intensions provides an epistemic conduit for our knowledge of (hyper-)intensions as abstract objects. Higher observational type theory might be one way to make first-order abstraction principles defined via inference rules, although not higher-order (...) abstraction principles, computable. The truth of my first-order abstraction principle for hyperintensions is grounded in its being possibly recursively enumerable i.e. Turing computable and the Turing machine being physically implementable. Epistemic modality and hyperintensionality can thus be shown to be both a compelling and a materially adequate candidate for the fundamental structure of mental representational states, comprising a fragment of the language of thought. (shrink)

Biological ontologies are used to organize, curate, and interpret the vast quantities of data arising from biological experiments. While this works well when using a single ontology, integrating multiple ontologies can be problematic, as they are developed independently, which can lead to incompatibilities. The Open Biological and Biomedical Ontologies Foundry was created to address this by facilitating the development, harmonization, application, and sharing of ontologies, guided by a set of overarching principles. One challenge in reaching these goals was that the (...) OBO principles were not originally encoded in a precise fashion, and interpretation was subjective. Here we show how we have addressed this by formally encoding the OBO principles as operational rules and implementing a suite of automated validation checks and a dashboard for objectively evaluating each ontology’s compliance with each principle. This entailed a substantial effort to curate metadata across all ontologies and to coordinate with individual stakeholders. We have applied these checks across the full OBO suite of ontologies, revealing areas where individual ontologies require changes to conform to our principles. Our work demonstrates how a sizable federated community can be organized and evaluated on objective criteria that help improve overall quality and interoperability, which is vital for the sustenance of the OBO project and towards the overall goals of making data FAIR. Competing Interest StatementThe authors have declared no competing interest. (shrink)

The article tries to reconstruct the Wirkungsgeschichte of the De pace fidei and it focuses on some fundamental moments of its fate. Nicholas of Cusa was one of the first not just to recognize other religions' value, but also to individuate a source of richness in religious pluralism. His work had fortune since the years after its draft, the 1453, known and quoted by Eimerico da Campo, Giovanni of Segovia, Juan de Torquemada and Pope Pius II. The debate, alive and (...) still open, around the possible influence of the work to Italian humanistic context is reconstructed, in particular about Pico and Ficino. Trusted traces of reception of the work can be individuated in France, in authors like Bodin and Postel. Finally the article is focused on modern fate of the work in Germany: beyond the cultural contest into reception and translation had done, the work analyze the reception by the German philosopher Lessing and on his comparison with Cusanian ideas about the vision of tolerance elaborated by the last one. (shrink)

Tradução para o português da obra "História natural da religião", de David Hume. Tradução, apresentação e notas: Jaimir Conte. Editora da UNESP: São Paulo, 1ª ed. 2005.

Despite a large and multifaceted effort to understand the vast landscape of phenotypic data, their current form inhibits productive data analysis. The lack of a community-wide, consensus-based, human- and machine-interpretable language for describing phenotypes and their genomic and environmental contexts is perhaps the most pressing scientific bottleneck to integration across many key fields in biology, including genomics, systems biology, development, medicine, evolution, ecology, and systematics. Here we survey the current phenomics landscape, including data resources and handling, and the progress that (...) has been made to accurately capture relevant data descriptions for phenotypes. We present an example of the kind of integration across domains that computable phenotypes would enable, and we call upon the broader biology community, publishers, and relevant funding agencies to support efforts to surmount today's data barriers and facilitate analytical reproducibility. (shrink)

Critical race theorists and standpoint epistemologists argue that agents who are members of dominant social groups are often in a state of ignorance about the extent of their social dominance, where this ignorance is explained by these agents' membership in a socially dominant group (e.g., Mills 2007). To illustrate this claim bluntly, it is argued: 1) that many white men do not know the extent of their social dominance, 2) that they remain ignorant as to the extent of their dominant (...) social position even where this information is freely attainable, and 3) that this ignorance is due in part to the fact that they are white men. We argue that on Buchak's (2010, 2013) model of risk averse instrumental rationality, ignorance of one's privileges can be rational. This argument yields a new account of elite-group ignorance, why it may occur, and how it might be alleviated. (shrink)

ENG: We all have our own ideas about what it is like to be intelligent. Indeed, even the experts disagree on this topic. This has generated diverse theories on the nature of intelligence and its genetic and environmental bases. Many scientific and philosophical questions thus remain unaddressed: is it possible to characterize intelligence in scientific terms? What do IQ tests measure? How is intelligence influenced by genetics, epigenetics, and the environment? What are the ethical and social implications of the research (...) on this topic? This book aims to provide the readers with the conceptual resources to critically analyze scientific findings and orientate themselves in this multi-faceted debate across biology, psychology, neuroscience, philosophy, and anthropology. -/- ITA: Ognuno di noi ha una propria idea di cosa significhi essere intelligenti, tanto che anche gli scienziati esperti in materia hanno opinioni differenti al riguardo. Ciò ha contribuito a generare teorie contrastanti sulla natura dell’intelligenza e su quali siano le sue basi genetiche e ambientali. Non è un caso, dunque, che diverse domande scientifiche e filosofiche restino ancora aperte: è possibile caratterizzare scientificamente l’intelligenza? Cosa misurano i test del QI? In che modo genetica, epigenetica e ambiente influenzano l’intelligenza? Quali sono le implicazioni etiche e sociali della ricerca sull’argomento? Oltre ad analizzare questi problemi, il testo intende fornire gli strumenti concettuali necessari per leggere criticamente i dati scientifici e orientarsi in uno sfaccettato e affascinante dibattito a cavallo tra biologia, psicologia, neuroscienze, filosofia e antropologia. (shrink)

ITA: In che modo il nostro cervello è in grado di produrre quel tipo di comportamento flessibile e volto a specifici scopi che chiamiamo intelligenza? Le differenze cognitive tra individui sono dovute a una varietà di abilità mentali o a una sola? Questo articolo discute gli elementi centrali della teoria dell’intelligenza generale proposta da John Duncan nel volume How intelligence happens, tradotto recentemente in italiano e corredato da un capitolo conclusivo inedito. Prendendo le mosse dalla ricerca di Charles Spearman sull’intelligenza (...) generale e sui test d’intelligenza, Duncan caratterizza l’intelligenza nei termini di integrazione e controllo cognitivo. I dati neuroscientifici raccolti da Duncan suggeriscono che questi aspetti chiave del comportamento intelligente siano realizzati da un circuito cerebrale, chiamato multiple-demand system, in grado di scomporre problemi complessi in sotto-problemi più semplici e integrare informazioni da varie aree del cervello. ENG: How does our brain generate that sort of flexible and goal-directed behaviour that we call intelligence? Are individual differences in intelligence due to a variety of cognitive abilities or do they depend on one single mental ability? In this commentary, I revise and critically assess the key elements of John Duncan’s theory of general intelligence presented in the popular-science book How intelligence happens, recently translated into Italian and edited by F. Pavani, with a new final chapter. Starting from Charles Spearman’s research on a general intelligence factor and psychometric tests, Duncan advances a theory that characterises intelligence in terms of integration and cognitive control. Neuropsychological and neuroimaging data suggest that such key aspects of intelligent behaviour are realised by a brain network called a multiple-demand system, which is capable of decomposing complex problems into simpler sub-problems and then integrating information from different brain areas. (shrink)

Shepherd appears to endorse something like the following biconditonal regarding qualities and objects. □(An object, O, exists ↔ Some bundle of qualities, Q1, Q2, … Qn exists). There is a growing consensus in the secondary literature that she also takes the right side of this biconditional to ground the left side. I.e. Shepherd is a bundle theorist who takes an object to be nothing but a mass of qualities, or causal powers. I argue here that despite appearances, this interpretation reverses (...) Shepherd's actual view. I.e. I argue that for Shepherd qualities, or causal powers, are grounded in the intrinsic constitutions of objects. In the case of "external objects", these intrinsic constitutions are unknowable to us; in the case of "internal objects", we have direct knowledge of them. (shrink)

Natural/social kind essentialism is the view that natural kind categories, both living and non-living natural kinds, as well as social kinds (e.g., race, gender), are essentialized. On this view, artifactual kinds are not essentialized. Our view—teleological essentialism—is that a broad range of categories are essentialized in terms of teleology, including artifacts. Utilizing the same kinds of experiments typically used to provide evidence of essentialist thinking—involving superficial change (study 1), transformation of insides (study 2) and inferences about offspring (study 3)—we find (...) support for the view that a broad range of categories—living natural kinds, non-living natural kinds and artifactual kinds—are essentialized in terms of teleology. Study 4 tests a unique prediction of teleological essentialism and also provides evidence that people make inferences about purposes which in turn guide categorization judgments. (shrink)

Questa conferenza, in diretta dagli Stati Uniti (11/11), rappresenta la versione italiana della ricerca, precedentemente pubblicata in inglese dall'Accademia Tiberina, nel 2022.

This paper presents a uniform general account of regress problems in the form of a pentalemma—i.e., a set of five mutually inconsistent claims. Specific regress problems can be analyzed as instances of such a general schema, and this Regress Pentalemma Schema can be employed to generate deductively valid arguments from the truth of a subset of four claims to the falsity of the fifth. Thus, a uniform account of the nature of regress problems allows for an improved understanding of specific (...) regress objections or arguments, and, correspondingly, of the general logical geography of the debate about infinite regresses. This uniform approach is illustrated by a treatment of the classical epistemological problem of justification, but it encompasses a whole variety of cases including explanation and ontological grounding. Furthermore, this general account is compared and contrasted with the existing literature discussing argument schemata for regress objections, particularly with the work of Jan Willem Wieland. It is shown how such other schemata can be incorporated and superseded by the general Regress Pentalemma Schema. (shrink)

In the recent literature, it has been shown that the wave function in the de Broglie–Bohm theory can be regarded as a new kind of field, i.e., a "multi-field", in three-dimensional space. In this paper, I argue that the natural framework for the multi-field is the original second-order Bohm’s theory. In this context, it is possible: i) to construe the multi-field as a real-valued scalar field; ii) to explain the physical interaction between the multi-field and the Bohmian particles; and iii) (...) to clarify the status of the energy-momentum conservation and the dynamics of the theory. (shrink)

Nosotres, biólogues, ecologistas y otres profesionales dedicados a proteger la vida, les escribimos con una solicitud urgente. Les pedimos muy comedidamente que su organización o institución emita un comunicado oficial condenando la crisis en curso y abordando los impactos ambientales y humanitarios en Palestina.

Many philosophers insist that the revisionary metaphysician—i.e., the metaphysician who offers a metaphysical theory which conflicts with folk intuitions—bears a special burden to explain why certain folk intuitions are mistaken. I show how evidence from cognitive science can help revisionist discharge this explanatory burden. Focusing on composition and persistence, I argue that empirical evidence indicates that the folk operate with a promiscuous teleomentalist view of composition and persistence. The folk view, I argue, deserves to be debunked. In this way, I (...) take myself to have illustrated one key role cognitive science can play in metaphysics; namely by helping the revisionary metaphysician discharge the explanatory burden of providing a plausible explanation of how the folk have gone wrong. (shrink)

Epistemic constitutivism (EC) holds that the nature of believing is such that it gives rise to a standard of correctness and that other epistemic normative notions (e.g., reasons for belief) can be explained in terms of this standard. If defensible, this view promises an attractive and unifying account of epistemic normativity. However, EC faces a forceful objection: that constitutive standards of correctness are never enough for generating normative reasons. This paper aims to defend EC in the face of this objection. (...) I do so in two steps. First, I dispute a crucial assumption underlying the case against EC: that constitutive standards of correctness in general are ‘reason-giving’ only if and because there is also a prior reason to comply with them. Second, I outline a strategy of how EC can meet the challenge of explaining what’s special about the activity of believing such that, unlike other standard-governed activities, it is capable of generating normative reasons. (shrink)

Computers may help us to better understand (not just verify) arguments. In this article we defend this claim by showcasing the application of a new, computer-assisted interpretive method to an exemplary natural-language ar- gument with strong ties to metaphysics and religion: E. J. Lowe’s modern variant of St. Anselm’s ontological argument for the existence of God. Our new method, which we call computational hermeneutics, has been particularly conceived for use in interactive-automated proof assistants. It aims at shedding light on the (...) meanings of words and sentences by framing their inferential role in a given argument. By employing automated theorem reasoning technology within interactive proof assistants, we are able to drastically reduce (by several orders of magnitude) the time needed to test the logical validity of an argu- ment’s formalization. As a result, a new approach to logical analysis, inspired by Donald Davidson’s account of radical interpretation, has been enabled. In computational hermeneutics, the utilization of automated reasoning tools ef- fectively boosts our capacity to expose the assumptions we indirectly commit ourselves to every time we engage in rational argumentation and it fosters the explicitation and revision of our concepts and commitments. (shrink)

Context — Children and adults with psychopathic traits and conduct or oppositional defiant disorder demonstrate poor decision making and are impaired in reversal learning. However, the neural basis of this impairment has not previously been investigated. Furthermore, despite high comorbidity of psychopathic traits and attention deficit/hyperactivity disorder, to our knowledge, no research has attempted to distinguish neural correlates of childhood psychopathic traits and attention-deficit/hyperactivity disorder. Objective—To determine the neural regions that underlie the reversal learning impairments in children with psychopathic traits (...) plus conduct or oppositional defiant disorder. Design — Case-control study. Setting — Government clinical research institute. Participants — Forty-two adolescents aged 10 to 17 years: 14 with psychopathic traits and oppositional defiant disorder or conduct disorder, 14 with attention-deficit/hyperactivity disorder only, and 14 healthy controls. Main Outcome Measure — Blood oxygenation level–dependent signal as measured via functional magnetic resonance imaging during a probabilistic reversal task. Results — Children with psychopathic traits showed abnormal responses within the ventromedial prefrontal cortex (Brodmann area 10) during punished reversal errors compared with children wit hattention deficit/hyperactivity disorder and healthy children (P < .05 corrected for multiple comparisons). Conclusions — To our knowledge, this study provides the first evidence of abnormal ventromedial prefrontal cortex responsiveness in children with psychopathic traits and demonstrates this dysfunction was not attributable to comorbid attention-deficit/hyperactivity disorder. These findings suggest that reversal learning impairments in patients with developmental psychopathic traits relate to abnormal processing of reinforcement information. (shrink)

Among the many forms of artistic expression that characterize the digital era, remix occupies a rather central position. At the same time, however, the success of remix as an artistic practice raises several hard questions. What is original and what is derived? How can we sort out and make sense of questions concerning origination and derivation in situations where one thing is appropriated, reused, and repurposed for something else? What theory of moral and aesthetic value can accommodate and explain these (...) situations where authorship, authority, and origination are already distributed across a network of derivations, borrowings, and re-appropriated found objects? This paper develops a response to these questions, and it does so in three steps or movements. The first briefly introduces the concept of remix and the opportunities and challenges that this now wide-spread, content creation practice presents to existing models and theories of moral and aesthetic value. The second outlines the three elements of what I call “remixology”—a new axiology (or theory of moral and aesthetic value) that is designed to scale to these new opportunities and challenges. The third and final movement investigates the consequences of this proposal, demonstrating how remixology can be read backwards through time, providing us with some new perspectives on artistry and creativity in all human endeavors, and read forwards into the emerging challenges that have been made available by innovations in algorithmic content generation and computational creativity. (shrink)

• Aggregates of previously isolated cells of Hydra are capable, under suitable solvant conditions, of regeneration forming complete animals. In a first stage, ecto- and endodermal cells sort out, producing the bilayered hollow structure characteristic of Hydra tissue; thereafter, heads are formed (even if the original cell preparation contained no head cells), eventually leading to the separation of normal animals with head, body column and foot. Hydra appears to be the highest type of organism that allows for regeneration of the (...) entire structure from random cell aggregates. The system is particularly useful for studying cell interactions, tissue polarity, pattern formation, and cell differentiation. (shrink)