Results for 'Bert R. E. Klagges'

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  1.  48
    Philosophie und biomedizinische Forschung.Barry Smith & Bert R. E. Klagges - 2005 - Allgemeine Zeitschrift für Philosophie 30 (1):5–26.
    Die bahnbrechenden wissenschaftlichen Ergebnisse der letzten Jahre erzwingen eine neue philosophische Auseinandersetzung mit den Grundkategorien der Biologie und der benachbarten Disziplinen. Insbesondere die Anwendung neuer informationstechnischer Mittel in der biomedizinischen Forschung und die damit verbundene, kontinuierlich zunehmende Datenflut sowie die Notwendigkeit, ihrer Herr zu werden, erfordern ein konsequentes Nachdenken darüber, wie biologische Daten systematisiert und klassifiziert werden können. Dafür wiederum bedarf es robuster Theorien von Grundbegriffen wie Art, Spezies, Teil, Ganzes, Funktion, Prozess, Fragment, Sequenz, Expression, Grenze, Locus, Umwelt, System usw. (...)
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  2.  90
    Relations in Biomedical Ontologies.Barry Smith, Werner Ceusters, Bert Klagges, Jacob Köhler, Anand Kuma, Jane Lomax, Chris Mungall, , Fabian Neuhaus, Alan Rector & Cornelius Rosse - 2005 - Genome Biology 6 (5):R46.
    To enhance the treatment of relations in biomedical ontologies we advance a methodology for providing consistent and unambiguous formal definitions of the relational expressions used in such ontologies in a way designed to assist developers and users in avoiding errors in coding and annotation. The resulting Relation Ontology can promote interoperability of ontologies and support new types of automated reasoning about the spatial and temporal dimensions of biological and medical phenomena.
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  3. Free Will as Involving Determination and Inconceivable Without It.R. E. Hobart - 1934 - Mind 43 (169):1-27.
    The thesis of this article is that there has never been any ground for the controversy between the doctrine of free will and determinism, that it is based upon a misapprehension, that the two assertions are entirely consistent, that one of them strictly implies the other, that they have been opposed only because of our natural want of the analytical imagination. In so saying I do not tamper with the meaning of either phrase. That would be unpardonable. I mean free (...)
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  4.  63
    Philosophy and Biomedical Information Systems.Barry Smith & Bert Klagges - 2008 - In Katherine Munn & Barry Smith (eds.), Applied Ontology: An Introduction. Ontos. pp. 17-30.
    The pathbreaking scientific advances of recent years call for a new philosophical consideration of the fundamental categories of biology and its neighboring disciplines. Above all, the new information technologies used in biomedical research, and the necessity to master the continuously growing flood of data that is associated therewith, demand a profound and systematic reflection on the systematization and classification of biological data. This, however, demands robust theories of basic concepts such as kind, species, part, whole, function, process, fragment, sequence, expression, (...)
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  5.  55
    Better No Longer to Be.R. Mcgregor & E. Sullivan-Bissett - 2012 - South African Journal of Philosophy 31 (1):55-68.
    David Benatar argues that coming into existence is always a harm, and that – for all of us unfortunate enough to have come into existence – it would be better had we never come to be. We contend that if one accepts Benatar’s arguments for the asymmetry between the presence and absence of pleasure and pain, and the poor quality of life, one must also accept that suicide is preferable to continued existence, and that his view therefore implies both anti-natalism (...)
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  6. Moral Notions, with Three Papers on Plato.Alan Tapper, R. E. Ewin & Julius Kovesi (eds.) - 2004 - Christchurch, NZ: Cybereditions.
    Morality is often thought of as non-rational or sub-rational. In Moral Notions, first published in 1967, Julius Kovesi argues that the rationality of morality is built into the way we construct moral concepts. In showing this he also resolves the old Humean conundrum of the relation between 'facts' and 'values'. And he puts forward a method of reasoning that might make 'applied ethics' (at present largely a hodge-podge of opinions) into a constructive discipline. Kovesi's general theory of concepts - important (...)
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  7.  47
    Test.R. E. Ives - manuscript
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  8. The Use (and Misuse) of 'Cognitive Enhancers' by Students at an Academic Health Sciences Center.J. Bossaer, J. A. Gray, S. E. Miller, V. C. Gaddipati, R. E. Enck & G. G. Enck - 2013 - Academic Medicine (7):967-971.
    Purpose Prescription stimulant use as “cognitive enhancers” has been described among undergraduate college students. However, the use of prescription stimulants among future health care professionals is not well characterized. This study was designed to determine the prevalence of prescription stimulant misuse among students at an academic health sciences center. -/- Method Electronic surveys were e-mailed to 621 medical, pharmacy, and respiratory therapy students at East Tennessee State University for four consecutive weeks in fall 2011. Completing the survey was voluntary and (...)
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  9.  41
    MacIntyre and Kovesi on the Nature of Moral Concepts.Alan Tapper & R. E. Ewin - 2012 - In Alan Tapper & Brian Mooney (eds.), Meaning and Morality: Essays on the Philosophy of Julius Kovesi. Leiden: Brill. pp. 123-37.
    Julius Kovesi was a moral philosopher contemporary with Alasdair MacIntyre, and dealing with many of the same questions as MacIntyre. In our view, Kovesi’s moral philosophy is rich in ideas and worth revisiting. MacIntyre agrees: Kovesi’s Moral Notions, he has said, is ‘a minor classic in moral philosophy that has not yet received its due’. Kovesi was not a thinker whose work fits readily into any one tradition. Unlike the later MacIntyre, he was not a Thomistic Aristotelian, nor even an (...)
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  10.  65
    Sulla Filosofia Italiana Recente di E. O. Burman.Täljedal Inge-Bert - manuscript
    Erik Olof Burman (1845–1929) was professor of practical philosophy at the University of Uppsala, Sweden, between 1896 and 1910. In 1879 he published a long essay entitled ”Om den nyare italienska filosofien” (”On recent Italian philosophy”). About half the essay is devoted to the philosophical system of Antonio Rosmini (1797–1855), the second half to that of Vincenzo Gioberti (1801–1852). The text is mainly descriptive, apparently aiming at informing Swedish colleagues about the situation in Italy. However, there are also passages revealing (...)
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  11. Providing Free Heroin to Addicts Participating in Research - Ethical Concerns and the Question of Voluntariness.Edmund Henden & Bærøe Kristine - 2014 - The Psychiatric Bulletin 38 (4):1-4.
    Providing heroin to heroin addicts taking part in medical trials to assess the effectiveness of the drug as a treatment alternative, breaches ethical research standards, some ethicists maintain. Heroin addicts, they say, are unable to consent voluntarily to take part in these trials. Other ethicists disagree. In our view, both sides of the debate have an inadequate understanding of voluntariness. In this article we therefore offer a fuller conception, one which allows for a more flexible, case-to-case approach in which some (...)
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  12. Der „kontrollierte individuelle Heilversuch“ als neues Instrument bei der klinischen Erstanwendung risikoreicher Therapieformen – Ethische Analyse einer somatischen Gentherapie für das Wiskott-Aldrich-Syndrom.Thomas Heinemann, Bert Heinrichs, Christoph Klein, Michael Fuchs & Dietmar Hübner - 2006 - Jahrbuch für Wissenschaft Und Ethik 11 (1):153-199.
    Das Wiskott-Aldrich-Syndrom (WAS), ein genetisch bedingter Immundefekt mit klinischer Manifestation im Kleinkindalter, wird voraussichtlich in näherer Zukunft erstmals versuchsweise durch eine somatische Gentherapie behandelt werden. Im vor- liegenden Beitrag werden die wichtigsten medizinisch-naturwissenschaftlichen Fakten dieses Krankheitsbildes sowie die bisherigen Erfahrungen mit somatischen Gentherapien bei anderen Immunmangelsyndromen ausführlich dargestellt. Sodann erfolgt eine ethische Analyse eines möglichen gentherapeutischen Eingriffs bei WAS-Patienten, bei der die spezifischen Aspekte des Wiskott-Aldrich-Syndroms – insbesondere die fast ausschließliche Betroffenheit von Kindern sowie die unterschiedlich aussichtsreiche Alter- nativoption einer (...)
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  13. Comparing the Understanding of Subjects Receiving a Candidate Malaria Vaccine in the United States and Mali.R. D. Ellis, I. Sagara, A. Durbin, A. Dicko, D. Shaffer, L. Miller, M. H. Assadou, M. Kone, B. Kamate, O. Guindo, M. P. Fay, D. A. Diallo, O. K. Doumbo, E. J. Emanuel & J. Millum - 2010 - American Journal of Tropical Medicine and Hygiene 83 (4):868-72.
    Initial responses to questionnaires used to assess participants' understanding of informed consent for malaria vaccine trials conducted in the United States and Mali were tallied. Total scores were analyzed by age, sex, literacy (if known), and location. Ninety-two percent (92%) of answers by United States participants and 85% of answers by Malian participants were correct. Questions more likely to be answered incorrectly in Mali related to risk, and to the type of vaccine. For adult participants, independent predictors of higher scores (...)
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  14.  78
    Rosmini in Swedish Perspective.Täljedal Inge-Bert - 2016 - Rosmini Studies 3:249–257.
    Antonio Rosmini is practically unknown in Lutheran Sweden. Apparently, only one significant Swedish text has been published about his philosophy, an essay in 1879 by Professor E.O. Burman at the University of Uppsala. After a brief introduction of Burman, some illustrative excerpts from his essay are presented in Italian translation.
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  15. Spatial Opinion Dynamics and the Effects of Two Types of Mixing.Bert Baumgaertner, Peter A. Fetros, Stephen M. Krone & Rebecca T. Tyson - 2018 - Physical Review E 98 (2):022310.
    Spatially situated opinions that can be held with different degrees of conviction lead to spatiotemporal patterns such as clustering (homophily), polarization, and deadlock. Our goal is to understand how sensitive these patterns are to changes in the local nature of interactions. We introduce two different mixing mechanisms, spatial relocation and nonlocal interaction (“telephoning”), to an earlier fully spatial model (no mixing). Interestingly, the mechanisms that create deadlock in the fully spatial model have the opposite effect when there is a sufficient (...)
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  16. Contemplative Science: An Insider's Prospectus.W. B. Britton, A. C. Brown, C. T. Kaplan, R. E. Goldman, M. Deluca, R. Rojiani, H. Reis, M. Xi, J. C. Chou, F. McKenna, P. Hitchcock, Tomas Rocha, J. Himmelfarb, D. M. Margolis, N. F. Halsey, A. M. Eckert & T. Frank - 2013 - New Directions for Teaching and Learning 134:13-29.
    This chapter describes the potential far‐reaching consequences of contemplative higher education for the fields of science and medicine.
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  17. Aporia and Conversion: A Critical Discussion of R. E. Allen's "Plato's Parmenides".Mitchell Miller - 1987 - Review of Metaphysics 41 (2):355 - 368.
    A appreciation and critical discussion of RE Allen's Plato's Parmenides. I argue that, contra Allen, the Parmenides is not an aporetic dialogue and that the eight hypotheses are not governed by the so-called "dilemma of participation." Rather, the apparent contradictions between and within the hypotheses function to elicit from the reader a distinction in kind between the sorts of one that forms, on the one hand, and their sensible participants, on the other, are and to illumine the 'relation' of participation.
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  18. Evolution of Individuality: A Case Study in the Volvocine Green Algae.Erik R. Hanschen, Dinah R. Davison, Zachariah I. Grochau-Wright & Richard E. Michod - 2017 - Philosophy, Theory, and Practice in Biology 9 (3).
    All disciplines must define their basic units and core processes. In evolutionary biology, the core process is natural selection and the basic unit of selection and adaptation is the individual. To operationalize the theory of natural selection we must count individuals, as they are the bearers of fitness. While canonical individuals have often been taken to be multicellular organisms, the hierarchy of life shows that new kinds of individuals have evolved. A variety of criteria have been used to define biological (...)
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  19. Paraconsistent Belief Revision Based on a Formal Consistency Operator.Rafael R. Testa, Marcelo E. Coniglio & Márcio M. Ribeiro - 2015 - CLE E-Prints 15 (8):01-11.
    In this paper two systems of AGM-like Paraconsistent Belief Revision are overviewed, both defined over Logics of Formal Inconsistency (LFIs) due to the possibility of defining a formal consistency operator within these logics. The AGM° system is strongly based on this operator and internalize the notion of formal consistency in the explicit constructions and postulates. Alternatively, the AGMp system uses the AGM-compliance of LFIs and thus assumes a wider notion of paraconsistency - not necessarily related to the notion of formal (...)
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  20. Political Legitimacy in Decisions About Experiments in Solar Radiation Management.David R. Morrow, Robert E. Kopp & Michael Oppenheimer - 2013 - In William C. G. Burns & Andrew Strauss (eds.), Climate Change Geoengineering: Philosophical Perspectives, Legal Issues, and Governance Frameworks. Cambridge University Press.
    Some types of solar radiation management (SRM) research are ethically problematic because they expose persons, animals, and ecosystems to significant risks. In our earlier work, we argued for ethical norms for SRM research based on norms for biomedical research. Biomedical researchers may not conduct research on persons without their consent, but universal consent is impractical for SRM research. We argue that instead of requiring universal consent, ethical norms for SRM research require only political legitimacy in decision-making about global SRM trials. (...)
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  21. I and Tao: Martin Buber's Encounter with Chuang Tzu.Robert E. Allinson & Jonathan R. Herman - 1998 - Philosophy East and West 48 (3):529.
    This review confirms Herman’s work as a praiseworthy contribution to East-West and comparative philosophical literature. Due credit is given to Herman for providing English readers with access to Buber’s commentary on, a personal translation of, the Chuang-Tzu; Herman’s insight into the later influence of I and Thou on Buber’s understanding of Chuang-Tzu and Taoism is also appropriately commended. In latter half of this review, constructive criticisms of Herman’s work are put forward, such as formatting inconsistencies, a tendency toward verbosity and (...)
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  22. Externalizing Psychopatholog Yand the Error-Related Negativity.J. R. Hall, E. M. Bernat & C. J. Patrick - 2007 - Psychological Science 18 (4):326-333.
    Prior research has demonstrated that antisocial behavior, substance-use disorders, and personality dimensions of aggression and impulsivity are indicators of a highly heritable underlying dimension of risk, labeled externalizing. Other work has shown that individual trait constructs within this psychopathology spectrum are associated with reduced self-monitoring, as reflected by amplitude of the error-related negativity (ERN) brain response. In this study of undergraduate subjects, reduced ERN amplitude was associated with higher scores on a self-report measure of the broad externalizing construct that links (...)
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  23. An Ethical Framework for Global Vaccine Allocation.Ezekiel J. Emanuel, Govind Persad, Adam Kern, Allen E. Buchanan, Cecile Fabre, Daniel Halliday, Joseph Heath, Lisa M. Herzog, R. J. Leland, Ephrem T. Lemango, Florencia Luna, Matthew McCoy, Ole F. Norheim, Trygve Ottersen, G. Owen Schaefer, Kok-Chor Tan, Christopher Heath Wellman, Jonathan Wolff & Henry S. Richardson - 2020 - Science 1:DOI: 10.1126/science.abe2803.
    In this article, we propose the Fair Priority Model for COVID-19 vaccine distribution, and emphasize three fundamental values we believe should be considered when distributing a COVID-19 vaccine among countries: Benefiting people and limiting harm, prioritizing the disadvantaged, and equal moral concern for all individuals. The Priority Model addresses these values by focusing on mitigating three types of harms caused by COVID-19: death and permanent organ damage, indirect health consequences, such as health care system strain and stress, as well as (...)
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  24. Promoting Coherent Minimum Reporting Guidelines for Biological and Biomedical Investigations: The MIBBI Project.Chris F. Taylor, Dawn Field, Susanna-Assunta Sansone, Jan Aerts, Rolf Apweiler, Michael Ashburner, Catherine A. Ball, Pierre-Alain Binz, Molly Bogue, Tim Booth, Alvis Brazma, Ryan R. Brinkman, Adam Michael Clark, Eric W. Deutsch, Oliver Fiehn, Jennifer Fostel, Peter Ghazal, Frank Gibson, Tanya Gray, Graeme Grimes, John M. Hancock, Nigel W. Hardy, Henning Hermjakob, Randall K. Julian, Matthew Kane, Carsten Kettner, Christopher Kinsinger, Eugene Kolker, Martin Kuiper, Nicolas Le Novere, Jim Leebens-Mack, Suzanna E. Lewis, Phillip Lord, Ann-Marie Mallon, Nishanth Marthandan, Hiroshi Masuya, Ruth McNally, Alexander Mehrle, Norman Morrison, Sandra Orchard, John Quackenbush, James M. Reecy, Donald G. Robertson, Philippe Rocca-Serra, Henry Rodriguez, Heiko Rosenfelder, Javier Santoyo-Lopez, Richard H. Scheuermann, Daniel Schober, Barry Smith & Jason Snape - 2008 - Nature Biotechnology 26 (8):889-896.
    Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...)
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  25. Review of Bert van den Brink and David Owen (eds.), Recognition and Power. Axel Honneth and the Tradition of Critical Social Theory. [REVIEW]Marco Solinas - 2010 - Iride: Filosofia e Discussione Pubblica (59):223-224.
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  26. Musica E Weltanschauung. Opera Musicale, Filosofia, Cultura.R. Martinelli - 2013 - Aisthesis: Pratiche, Linguaggi E Saperi Dell’Estetico 6:303-315.
    Can music express the world-view of a certain composer, or of a certain historical era – and how? In 19th Century, the wide-ranging philosophical implications of this question raised an intriguing quarrel between the formalists’ scepticism as to this point and their various opponents. Starting from the case study of the German psychologist and philosopher of music Georg Anschütz, it is argued that allowing for a systematic link of music and the world-views easily turns into the far more demanding claim (...)
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  27.  15
    To Die or Not to Die. [REVIEW]Larry R. Churchill, Daniel Callahan, Elizabeth A. Linehan, Anne E. Thal, Frances A. Graves, Alice V. Prendergast, Donald G. Flory & John Hardwig - 1997 - Hastings Center Report 27 (6):4.
    Letters commenting on Hardwig, J "Is There a Duty to Die?" with a reply to those letters by the author.
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  28.  13
    Trinta e Cinco Anos de Pesquisas Sobre Kant: Uma Interpretação Retrospectiva.Stephen R. Palmquist - 2017 - Kant E-Prints: Revista Internacional de Filosofia 12:56-73.
    The autobiographical essay, "Thirty-five Years of Research on Kant: a Retrospective Overview", is here translated into Portuguese by Henrique Azevedo. The English version has not been published, but can be provided to interested readers, upon request.
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  29. Neural Correlates of Error-Related Learning Deficits in Individuals with Psychopathy.A. K. L. von Borries, Inti A. Brazil, B. H. Bulten, J. K. Buitelaar, R. J. Verkes & E. R. A. de Bruijn - 2010 - Psychological Medicine 40:1559–1568.
    The results are interpreted in terms of a deficit in initial rule learning and subsequent generalization of these rules to new stimuli. Negative feedback is adequately processed at a neural level but this information is not used to improve behaviour on subsequent trials. As learning is degraded, the process of error detection at the moment of the actual response is diminished. Therefore, the current study demonstrates that disturbed error-monitoring processes play a central role in the often reported learning deficits in (...)
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  30. Platos Idee des Guten.R. FERBER - 2015 - St. Augustin: Academia Verlag.
    At the centre of the monograph (1984, first edition) lies a detailed interpretation and critique of the idea of the Good in the Republic. The main thesis of the interpretation runs as follows: The idea of the Good functions as a third item between thinking and being. The main purpose of the monograph is to introduce the systematic problem of the third item via the historical problem of the idea of the Good. The second, enlarged edition (1989) gives a new (...)
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  31. AGM-Like Paraconsistent Belief Change.Rafael R. Testa, Marcelo E. Coniglio & Marcio M. Ribeiro - 2017 - Logic Journal of the IGPL 25 (4):632-672.
    Two systems of belief change based on paraconsistent logics are introduced in this article by means of AGM-like postulates. The first one, AGMp, is defined over any paraconsistent logic which extends classical logic such that the law of excluded middle holds w.r.t. the paraconsistent negation. The second one, AGMo , is specifically designed for paraconsistent logics known as Logics of Formal Inconsistency (LFIs), which have a formal consistency operator that allows to recover all the classical inferences. Besides the three usual (...)
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  32. Abnormal Ventromedial Prefrontal Cortex Function in Children With Psychopathic Traits During Reversal Learning.Elizabeth C. Finger, Abigail A. Marsh, Derek G. Mitchell, Marguerite E. Reid, Courtney Sims, Salima Budhani, David S. Kosson, Gang Chen, Kenneth E. Towbin, Ellen Leibenluft, Daniel S. Pine & James R. Blair - 2008 - Archives of General Psychiatry 65: 586–594.
    Context — Children and adults with psychopathic traits and conduct or oppositional defiant disorder demonstrate poor decision making and are impaired in reversal learning. However, the neural basis of this impairment has not previously been investigated. Furthermore, despite high comorbidity of psychopathic traits and attention deficit/hyperactivity disorder, to our knowledge, no research has attempted to distinguish neural correlates of childhood psychopathic traits and attention-deficit/hyperactivity disorder. Objective—To determine the neural regions that underlie the reversal learning impairments in children with psychopathic traits (...)
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  33. La Prudenza Del Carattere. Kant E I Due Volti Dell'antropologia Pragmatica.R. Martinelli - 2013 - In S. Guidi & A. Lucci (eds.), The Domain of the Human. Anthropological Frontiers in Modern and Contemporary Thought. pp. 93-104.
    The essay investigates the question of the transition from a physiological view of anthropology to one ‘from a pragmatic point of view’ in the work of Immanuel Kant. The concepts this thinking hinges on are those of ‘prudence’ and ‘character’, which are crucial for the break that Kant’s anthropological thought represents with that of earlier and later philosophy.
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  34. Metafisica Ingenua. Il Problema Delle Categorie in Paolo Bozzi E Carl Stumpf.R. Martinelli - 2013 - Teorie and Modelli 18 (1):63-76.
    The paper compares the ideas developed by Bozzi and Stumpf with regard to unity, identity, and causality. Although Bozzi’s formulation is independent from the one made by Stumpf in his Erkenntnislehre, these two positions share the same innovative importance granted to perceptual experience and to the problem of the origin of categories. Thus, despite different levels of awareness and formalization, in both authors we see the features of what we can call – analogous- ly to Bozzi’s naïve physics – a (...)
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  35. Foucault, Michel . Fearless Speech Cambridge, MA: Semiotext(E), 2001.Fernando R. Zapata - 2005 - Foucault Studies 2:150-153.
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  36. Criatividade, Transhumanismo e a metáfora Co-criador Criado.Eduardo R. Cruz - 2017 - Quaerentibus 5 (9):42-64.
    The goal of Transhumanism is to change the human condition through radical enhancement of its positive traits and through AI (Artificial Intelligence). Among these traits the transhumanists highlight creativity. Here we first describe human creativity at more fundamental levels than those related to the arts and sciences when, for example, childhood is taken into account. We then admit that creativity is experienced on both its bright and dark sides. In a second moment we describe attempts to improve creativity both at (...)
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  37. Finding Our Way Through Phenotypes.Andrew R. Deans, Suzanna E. Lewis, Eva Huala, Salvatore S. Anzaldo, Michael Ashburner, James P. Balhoff, David C. Blackburn, Judith A. Blake, J. Gordon Burleigh, Bruno Chanet, Laurel D. Cooper, Mélanie Courtot, Sándor Csösz, Hong Cui, Barry Smith & Others - 2015 - PLoS Biol 13 (1):e1002033.
    Despite a large and multifaceted effort to understand the vast landscape of phenotypic data, their current form inhibits productive data analysis. The lack of a community-wide, consensus-based, human- and machine-interpretable language for describing phenotypes and their genomic and environmental contexts is perhaps the most pressing scientific bottleneck to integration across many key fields in biology, including genomics, systems biology, development, medicine, evolution, ecology, and systematics. Here we survey the current phenomics landscape, including data resources and handling, and the progress that (...)
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  38. Discussion of “Biomedical Informatics: We Are What We Publish”.Geissbuhler Antoine, W. E. Hammond, A. Hasman, R. Hussein, R. Koppel, C. A. Kulikowski, V. Maojo, F. Martin-Sanchez, P. W. Moorman, Moura La, F. G. De Quiros, M. J. Schuemle, Barry Smith & J. Talmon - 2013 - Methods of Information in Medicine 52 (6):547-562.
    This article is part of a For-Discussion-Section of Methods of Information in Medicine about the paper "Biomedical Informatics: We Are What We Publish", written by Peter L. Elkin, Steven H. Brown, and Graham Wright. It is introduced by an editorial. This article contains the combined commentaries invited to independently comment on the Elkin et al. paper. In subsequent issues the discussion can continue through letters to the editor.
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  39. Novel Sequence Feature Variant Type Analysis of the HLA Genetic Association in Systemic Sclerosis.R. Karp David, Marthandan Nishanth, G. E. Marsh Steven, Ahn Chul, C. Arnett Frank, S. DeLuca David, D. Diehl Alexander, Dunivin Raymond, Eilbeck Karen, Feolo Michael & Barry Smith - 2009 - Human Molecular Genetics 19 (4):707-719.
    Significant associations have been found between specific human leukocyte antigen (HLA) alleles and organ transplant rejection, autoimmune disease development, and the response to infection. Traditional searches for disease associations have conventionally measured risk associated with the presence of individual HLA alleles. However, given the high level of HLA polymorphism, the pattern of amino acid variability, and the fact that most of the HLA variation occurs at functionally important sites, it may be that a combination of variable amino acid sites shared (...)
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  40.  48
    Review of R. Joyce, The Evolution of Morality (The MIT Press, 2006). [REVIEW]Diego E. Machuca - 2008 - Philosophy in Review 28 (5):343–346.
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  41. Review of R. Joyce & S. Kirchin (Eds.), A World Without Values: Essays on John Mackie’s Moral Error Theory (Springer, 2010). [REVIEW]Diego E. Machuca - 2011 - Philosophy in Review 31 (5):354-358.
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  42. Review of R. Bett (Trans.), Sextus Empiricus: Against the Physicists (CUP, 2012). [REVIEW]Diego E. Machuca - 2014 - British Journal for the History of Philosophy 22 (3):614-617.
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  43. Review of R. Bett (Ed.), The Cambridge Companion to Ancient Scepticism (CUP, 2010). [REVIEW]Diego E. Machuca - 2011 - British Journal for the History of Philosophy 19 (3):573 - 579.
    British Journal for the History of Philosophy, Volume 19, Issue 3, Page 573-579, May 2011.
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  44. Review of R. Fogelin, Walking the Tightrope of Reason: The Precarious Life of a Rational Animal (OUP, 2003). [REVIEW]Diego E. Machuca - 2006 - Dialogue 45 (1):188-191.
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  45. How Different Kinds of Disagreement Impact Folk Metaethical Judgments.James R. Beebe - 2014 - In Jennifer Cole Wright & Hagop Sarkissian (eds.), Advances in Experimental Moral Psychology. Bloomsbury Academic. pp. 167-187.
    Th e present article reports a series of experiments designed to extend the empirical investigation of folk metaethical intuitions by examining how different kinds of ethical disagreement can impact attributions of objectivity to ethical claims.
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  46. Happiness is Not Well-Being.Jason R. Raibley - 2012 - Journal of Happiness Studies 13 (6):1105-1129.
    This paper attempts to explain the conceptual connections between happiness and well-being. It first distinguishes episodic happiness from happiness in the personal attribute sense. It then evaluates two recent proposals about the connection between happiness and well-being: (1) the idea that episodic happiness and well-being both have the same fundamental determinants, so that a person is well-off to a particular degree in virtue of the fact that they are happy to that degree, and (2) the idea that happiness in the (...)
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  47.  70
    O Livre-Arbítrio em John R. Searle: Uma Contraposição do Naturalismo Biológico ao Fisicalismo e ao Funcionalismo.Daniel P. Nunes - 2014 - Dissertation, UNIVERSIDADE DE CAXIAS DO SUL
    This dissertation aims to examine whether John Searle’s biological naturalism is a more viable alternative to current physicalist and functionalist positions in dealing with the issue of free will. Thus, my strategy is to identify the assumptions of these lines of thought and their philosophical consequences. In order to accomplish this goal the concept of intrinsic intentionality is taken as a guide. I begin by defining what is meant by free will and go on to broadly characterize physicalist and functionalist (...)
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  48.  39
    Review of The Art of the Infinite by R. Kaplan, E. Kaplan 324p(2003).Michael Starks - 2016 - In Suicidal Utopian Delusions in the 21st Century: Philosophy, Human Nature and the Collapse of Civilization-- Articles and Reviews 2006-2017 2nd Edition Feb 2018. Michael Starks. pp. 619.
    This book tries to present math to the millions and does a pretty good job. It is simple and sometimes witty but often the literary allusions intrude and the text bogs down in pages of relentless math--lovely if you like it and horrid if you don´t. If you already know alot of math you will still probably find the discussions of general math, geometry, projective geometry, and infinite series to be a nice refresher. If you don´t know any and don´t (...)
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  49.  65
    Metaphysics of States of Affairs: Truthmaking, Universals, and a Farewell to Bradley’s Regress.Bo R. Meinertsen - 2018 - Springer Singapore.
    This book addresses the metaphysics of Armstrongian states of affairs, i.e. instantiations of naturalist universals by particulars. The author argues that states of affairs are the best candidate for truthmakers and, in the spirit of logical atomism, that we need no molecular truthmakers for positive truths. In the book's context, this has the pleasing result that there are no molecular states of affairs. Following this account of truthmaking, the author first shows that the particulars in (first-order) states of affairs are (...)
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  50. Realism, Ontology, and the Concept of Reality.R. Martinelli - 2014 - Etica E Politica 16 (2):526-532.
    This essay focuses on realism in ontology and on the problem of defining reality. According to the definition given by many realists, reality is independent of our thoughts, conceptual schemes, linguistic practices, etc. Yet, this merely negative definition of reality has some disadvantages: it implies a dualistic view, and it is incompatible with scientific realism. As an alternative, I introduce and discuss the traditional definition of reality as effectiveness, or capability of acting. I then attempt to determine to what extent (...)
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