Results for 'David Diehl'

966 found
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  1. Novel sequence feature variant type analysis of the HLA genetic association in systemic sclerosis.R. Karp David, Marthandan Nishanth, G. E. Marsh Steven, Ahn Chul, C. Arnett Frank, S. DeLuca David, D. Diehl Alexander, Dunivin Raymond, Eilbeck Karen, Feolo Michael & Barry Smith - 2009 - Human Molecular Genetics 19 (4):707-719.
    Significant associations have been found between specific human leukocyte antigen (HLA) alleles and organ transplant rejection, autoimmune disease development, and the response to infection. Traditional searches for disease associations have conventionally measured risk associated with the presence of individual HLA alleles. However, given the high level of HLA polymorphism, the pattern of amino acid variability, and the fact that most of the HLA variation occurs at functionally important sites, it may be that a combination of variable amino acid sites shared (...)
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  2. OBO Foundry in 2021: Operationalizing Open Data Principles to Evaluate Ontologies.Rebecca C. Jackson, Nicolas Matentzoglu, James A. Overton, Randi Vita, James P. Balhoff, Pier Luigi Buttigieg, Seth Carbon, Melanie Courtot, Alexander D. Diehl, Damion Dooley, William Duncan, Nomi L. Harris, Melissa A. Haendel, Suzanna E. Lewis, Darren A. Natale, David Osumi-Sutherland, Alan Ruttenberg, Lynn M. Schriml, Barry Smith, Christian J. Stoeckert, Nicole A. Vasilevsky, Ramona L. Walls, Jie Zheng, Christopher J. Mungall & Bjoern Peters - 2021 - BioaRxiv.
    Biological ontologies are used to organize, curate, and interpret the vast quantities of data arising from biological experiments. While this works well when using a single ontology, integrating multiple ontologies can be problematic, as they are developed independently, which can lead to incompatibilities. The Open Biological and Biomedical Ontologies Foundry was created to address this by facilitating the development, harmonization, application, and sharing of ontologies, guided by a set of overarching principles. One challenge in reaching these goals was that the (...)
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  3. Phenomenal Structuralism.David J. Chalmers - 2012 - In David Chalmers (ed.), Constructing the World. Oxford: Oxford University Press. pp. 412-422.
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  4. The computational and the representational language-of-thought hypotheses.David J. Chalmers - 2023 - Behavioral and Brain Sciences 46:e269.
    There are two versions of the language-of-thought hypothesis (LOT): Representational LOT (roughly, structured representation), introduced by Ockham, and computational LOT (roughly, symbolic computation) introduced by Fodor. Like many others, I oppose the latter but not the former. Quilty-Dunn et al. defend representational LOT, but they do not defend the strong computational LOT thesis central to the classical-connectionist debate.
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  5. Extended Cognition and Extended Consciousness.David Chalmers - 2019 - In Matteo Colombo, Elizabeth Irvine & Mog Stapleton (eds.), Andy Clark and his Critics. New York, NY: Oxford University Press.
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  6. Eight Arguments for First‐Person Realism.David Builes - 2024 - Philosophy Compass 19 (1):e12959.
    According to First-Person Realism, one's own first-person perspective on the world is metaphysically privileged in some way. After clarifying First-Person Realism by reference to parallel debates in the metaphysics of modality and time, I survey eight different arguments in favor of First-Person Realism.
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  7. Does thought require sensory grounding? From pure thinkers to large language models.David J. Chalmers - 2023 - Proceedings and Addresses of the American Philosophical Association 97:22-45.
    Does the capacity to think require the capacity to sense? A lively debate on this topic runs throughout the history of philosophy and now animates discussions of artificial intelligence. Many have argued that AI systems such as large language models cannot think and understand if they lack sensory grounding. I argue that thought does not require sensory grounding: there can be pure thinkers who can think without any sensory capacities. As a result, the absence of sensory grounding does not entail (...)
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  8. Evolving resolve.Walter Veit & David Spurrett - 2021 - Behavioral and Brain Sciences 44.
    The broad spectrum revolution brought greater dependence on skill and knowledge, and more demanding, often social, choices. We adopt Sterelny's account of how cooperative foraging paid the costs associated with longer dependency, and transformed the problem of skill learning. Scaffolded learning can facilitate cognitive control including suppression, whereas scaffolded exchange and trade, including inter-temporal exchange, can help develop resolve.
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  9. Motivational Limitations on the Demands of Justice.David Wiens - 2016 - European Journal of Political Theory 15 (3):333-352.
    Do motivational limitations due to human nature constrain the demands of justice? Among those who say no, David Estlund offers perhaps the most compelling argument. Taking Estlund’s analysis of “ability” as a starting point, I show that motivational deficiencies can constrain the demands of justice under at least one common circumstance — that the motivationally-deficient agent makes a good faith effort to overcome her deficiency. In fact, my argument implies something stronger; namely, that the demands of justice are constrained (...)
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  10. High Risk, Low Reward: A Challenge to the Astronomical Value of Existential Risk Mitigation.David Thorstad - 2023 - Philosophy and Public Affairs 51 (4):373-412.
    Philosophy &Public Affairs, Volume 51, Issue 4, Page 373-412, Fall 2023.
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  11. The Role of Consciousness in Grasping and Understanding.David Bourget - 2017 - Philosophy and Phenomenological Research 95 (2):285-318.
    One sometimes believes a proposition without grasping it. For example, a complete achromat might believe that ripe tomatoes are red without grasping this proposition. My aim in this paper is to shed light on the difference between merely believing a proposition and grasping it. I focus on two possible theories of grasping: the inferential theory, which explains grasping in terms of inferential role, and the phenomenal theory, which explains grasping in terms of phenomenal consciousness. I argue that the phenomenal theory (...)
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  12. Two Views on the Cognitive Brain.David L. Barack & John Krakauer - 2021 - Nature Reviews Neuroscience 22 (6).
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  13. Human Nature and the Limits (If Any) of Political Philosophy.David Estlund - 2011 - Philosophy and Public Affairs 39 (3):207-237.
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  14. Existential risk pessimism and the time of perils.David Thorstad - manuscript
    When our choice affects some other person and the outcome is unknown, it has been argued that we should defer to their risk attitude, if known, or else default to use of a risk avoidant risk function. This, in turn, has been claimed to require the use of a risk avoidant risk function when making decisions that primarily affect future people, and to decrease the desirability of efforts to prevent human extinction, owing to the significant risks associated with continued human (...)
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  15. Grounding and the argument from explanatoriness.David Mark Kovacs - 2017 - Philosophical Studies 174 (12):2927-2952.
    In recent years, metaphysics has undergone what some describe as a revolution: it has become standard to understand a vast array of questions as questions about grounding, a metaphysical notion of determination. Why should we believe in grounding, though? Supporters of the revolution often gesture at what I call the Argument from Explanatoriness: the notion of grounding is somehow indispensable to a metaphysical type of explanation. I challenge this argument and along the way develop a “reactionary” view, according to which (...)
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  16. How to ground powers.David Builes - 2024 - Analysis 84 (2):231-238.
    According to the grounding theory of powers, fundamental physical properties should be thought of as qualities that ground dispositions. Although this view has recently been defended by many different philosophers, there is no consensus for how the view should be developed within a broader metaphysics of properties. Recently, Tugby has argued that the view should be developed in the context of a Platonic theory of properties, where properties are abstract universals. I will argue that the view should not be developed (...)
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  17. Can We Detect Bias in Political Fact-Checking? Evidence from a Spanish Case Study.David Teira, Alejandro Fernandez-Roldan, Carlos Elías & Carlos Santiago-Caballero - 2023 - Journalism Practice 10.
    Political fact-checkers evaluate the truthfulness of politicians’ claims. This paper contributes to an emerging scholarly debate on whether fact-checkers treat political parties differently in a systematic manner depending on their ideology (bias). We first examine the available approaches to analyze bias and then present a new approach in two steps. First, we propose a logistic regression model to analyze the outcomes of fact-checks and calculate how likely each political party will obtain a truth score. We test our model with a (...)
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  18. Is Memory Merely Testimony from One's Former Self?David James Barnett - 2015 - Philosophical Review 124 (3):353-392.
    A natural view of testimony holds that a source's statements provide one with evidence about what the source believes, which in turn provides one with evidence about what is true. But some theorists have gone further and developed a broadly analogous view of memory. According to this view, which this essay calls the “diary model,” one's memory ordinarily serves as a means for one's present self to gain evidence about one's past judgments, and in turn about the truth. This essay (...)
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  19. The scope of longtermism.David Thorstad - forthcoming - Australasian Journal of Philosophy.
    Longtermism is the thesis that in a large class of decision situations, the best thing we can do is what is best for the long-term future. The scope question for longtermism asks: how large is the class of decision situations for which this is true? In this paper, I suggest that the scope of longtermism may be narrower than many longtermists suppose. I identify a restricted version of longtermism: swamping axiological strong longtermism (swamping ASL). I identify three scope-limiting factors - (...)
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  20. (1 other version)Ontological Choices and the Value-Free Ideal.David Ludwig - 2015 - Erkenntnis (6):1-20.
    The aim of this article is to argue that ontological choices in scientific practice undermine common formulations of the value-free ideal in science. First, I argue that the truth values of scientific statements depend on ontological choices. For example, statements about entities such as species, race, memory, intelligence, depression, or obesity are true or false relative to the choice of a biological, psychological, or medical ontology. Second, I show that ontological choices often depend on non-epistemic values. On the basis of (...)
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  21. The Quality of Thought.David Pitt - 2024 - Oxford, UK: Oxford University Press.
    This is a corrected version of the final proofs. I've fixed a number of typos, and corrected a blunder in chapter 4. In chapter 4 I say that 'this is this' is analytic, and 'this is not this' is antonymous. This is inconsistent with what I say in chapter 5, and not what I actually think. Rather, 'this is this' is taugologous, and 'this is not this' is contradictory. Analyticity and autnonmy are sense properties while tautologousness and contradictoriness are formal (...)
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  22. What Is It To Have A Language?David Balcarras - 2023 - Pacific Philosophical Quarterly 104 (4):837-866.
    This article defends the view that having a language just is knowing how to engage in communication with it. It also argues that, despite claims to the contrary, this view is compatible and complementary with the Chomskyan conception of language on which humans have languages in virtue of being in brain states realizing tacit knowledge of grammars for those languages.
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  23. From Multilevel Explanation to Downward Causation.David Yates - 2024 - In Alastair Wilson & Katie Robertson (eds.), Levels of Explanation. Oxford University Press.
    The causal closure of the physical poses a familiar causal exclusion problem for the special sciences that stems from the idea that if closure is true, then fundamental physical properties do all the causal work involved in bringing about physical effects. In this paper I aim to show that the strongest causal closure principle that is not ruled out by some simple physics in fact allows for a certain kind of downward causation, which in turn makes room for robust special (...)
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  24. On Our Moral Entanglements with Wild Animals.Gary David O’Brien - 2023 - Food Ethics 8 (15):1-8.
    In Just Fodder, Milburn argues for a relational account of our duties to animals. Following Clare Palmer, he argues that, though all animals have negative rights that we have a duty not to violate, we only gain positive obligations towards animals in the contexts of our relationships with them, which can be personal or political. He argues that human beings have collective positive duties towards domesticated animals, in virtue of the kind of relationship between us established by domestication. However, when (...)
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  25. Against the newer evidentialists.David Thorstad - 2023 - Philosophical Studies 180 (12):3511-3532.
    A new wave of evidentialist theorizing concedes that evidentialism may be extensionally incorrect as an account of all-things-considered rational belief. Nevertheless, these _newer evidentialists_ maintain that there is an importantly distinct type of epistemic rationality about which evidentialism may be the correct account. I argue that natural ways of developing the newer evidentialist position face opposite problems. One version, due to Christensen (Philos Phenomenol Res 103:501–517, 2021), may correctly describe what rationality requires, but does not entail the existence of a (...)
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  26. Inferential Justification and the Transparency of Belief.David James Barnett - 2016 - Noûs 50 (1):184-212.
    This paper critically examines currently influential transparency accounts of our knowledge of our own beliefs that say that self-ascriptions of belief typically are arrived at by “looking outward” onto the world. For example, one version of the transparency account says that one self-ascribes beliefs via an inference from a premise to the conclusion that one believes that premise. This rule of inference reliably yields accurate self-ascriptions because you cannot infer a conclusion from a premise without believing the premise, and so (...)
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  27. Necessary Conditions for Morally Responsible Animal Research.David Degrazia & Jeff Sebo - 2015 - Cambridge Quarterly of Healthcare Ethics 24 (4):420-430.
    In this paper, we present three necessary conditions for morally responsible animal research that we believe people on both sides of this debate can accept. Specifically, we argue that, even if human beings have higher moral status than nonhuman animals, animal research is morally permissible only if it satisfies (a) an expectation of sufficient net benefit, (b) a worthwhile-life condition, and (c) a no unnecessary-harm/qualified-basic-needs condition. We then claim that, whether or not these necessary conditions are jointly sufficient conditions of (...)
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  28. Disagreement and Public Controversy.David Christensen - 2014 - In Jennifer Lackey (ed.), Essays in Collective Epistemology. Oxford: Oxford University Press.
    One of Mill’s main arguments for free speech springs from taking disagreement as an epistemically valuable resource for fallible thinkers. Contemporary conciliationist treatments of disagreement spring from the same motivation, but end up seeing the epistemic implications of disagreement quite differently. Conciliationism also encounters complexities when transposed from the 2-person toy examples featured in the literature to the public disagreements among groups that give the issue much of its urgency. Group disagreements turn out to be in some ways more powerful (...)
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  29. Against direction of fit accounts of belief and desire.David Sobel & Copp - 2001 - Analysis 61 (1):44-53.
    The authors argue against direction of fit accounts of the distinction between belief and desire.
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  30. Belief is prior to knowledge.David Rose - 2015 - Episteme 12 (3):385-399.
    Orthodoxy has it that knowledge is a composite of belief and non-mental factors. However, Timothy Williamson suggests that orthodoxy implies that the concept of belief is acquired before the concept of knowledge, whereas developmental data suggest the reverse. More recently, Jennifer Nagel reviews the psychological evidence, building a psychological case that the concept of knowledge emerges prior to belief. I assess the psychological state of the art and find support for the opposite conclusion. Overall the empirical evidence supports the orthodox (...)
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  31. Cosmology and convention.David Merritt - 2017 - Studies in History and Philosophy of Science Part B: Studies in History and Philosophy of Modern Physics 57:41-52.
    I argue that some important elements of the current cosmological model are 'conventionalist’ in the sense defined by Karl Popper. These elements include dark matter and dark energy; both are auxiliary hypotheses that were invoked in response to observations that falsified the standard model as it existed at the time.
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  32. The Asceticism of the Phaedo: Pleasure, Purification, and the Soul’s Proper Activity.David Ebrey - 2017 - Archiv für Geschichte der Philosophie 99 (1):1-30.
    I argue that according to Socrates in the Phaedo we should not merely evaluate bodily pleasures and desires as worthless or bad, but actively avoid them. We need to avoid them because they change our values and make us believe falsehoods. This change in values and acceptance of falsehoods undermines the soul’s proper activity, making virtue and happiness impossible for us. I situate this account of why we should avoid bodily pleasures within Plato’s project in the Phaedo of providing Pythagorean (...)
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  33. The Unity of the Moral Domain.Jeremy David Fix - forthcoming - European Journal of Philosophy.
    What is the function of morality—what is it all about? What is the basis of morality—what explains our moral agency and patiency? This essay defends a unique Kantian answer to these questions. Morality is about securing our independence from each other by giving each other equal discretion over whether and how we interact. The basis of our moral agency and patiency is practical reason. The first half addresses objections that this account cannot explain the moral patiency of beings who are (...)
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  34. Existentialism: A Reconstruction.David Edward Cooper - 1990 - Malden, Mass.: Wiley-Blackwell.
    First published in 1990, _Existentialism_ is widely regarded as a classic introductory survey of the topic, and has helped to renew interest in existentialist philosophy. The author places existentialism within the great traditions of philosophy, and argues that it deserves as much attention from analytic philosophers as it has always received on the continent.
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  35. A theory of presumption for everyday argumentation.David M. Godden & Douglas N. Walton - 2007 - Pragmatics and Cognition 15 (2):313-346.
    The paper considers contemporary models of presumption in terms of their ability to contribute to a working theory of presumption for argumentation. Beginning with the Whatelian model, we consider its contemporary developments and alternatives, as proposed by Sidgwick, Kauffeld, Cronkhite, Rescher, Walton, Freeman, Ullmann-Margalit, and Hansen. Based on these accounts, we present a picture of presumptions characterized by their nature, function, foundation and force. On our account, presumption is a modal status that is attached to a claim and has the (...)
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  36. Counting distinctions: on the conceptual foundations of Shannon’s information theory.David Ellerman - 2009 - Synthese 168 (1):119-149.
    Categorical logic has shown that modern logic is essentially the logic of subsets (or "subobjects"). Partitions are dual to subsets so there is a dual logic of partitions where a "distinction" [an ordered pair of distinct elements (u,u′) from the universe U ] is dual to an "element". An element being in a subset is analogous to a partition π on U making a distinction, i.e., if u and u′ were in different blocks of π. Subset logic leads to finite (...)
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  37. A Language for Ontological Nihilism.Catharine Diehl - 2018 - Ergo: An Open Access Journal of Philosophy 5:971-996.
    According to ontological nihilism there are, fundamentally, no individuals. Both natural languages and standard predicate logic, however, appear to be committed to a picture of the world as containing individual objects. This leads to what I call the \emph{expressibility challenge} for ontological nihilism: what language can the ontological nihilist use to express her account of how matters fundamentally stand? One promising suggestion is for the nihilist to use a form of \emph{predicate functorese}, a language developed by Quine. This proposal faces (...)
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  38. The objectivity of local knowledge. Lessons from ethnobiology.David Ludwig - 2017 - Synthese 194 (12):4705-4720.
    This article develops an account of local epistemic practices on the basis of case studies from ethnobiology. I argue that current debates about objectivity often stand in the way of a more adequate understanding of local knowledge and ethnobiological practices in general. While local knowledge about the biological world often meets criteria for objectivity in philosophy of science, general debates about the objectivity of local knowledge can also obscure their unique epistemic features. In modification of Ian Hacking’s suggestion to discuss (...)
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  39. Thisnesses, Propositions, and Truth.David Ingram - 2018 - Pacific Philosophical Quarterly 99 (3):442-463.
    Presentists, who believe that only present objects exist, should accept a thisness ontology, since it can do considerable work in defence of presentism. In this paper, I propose a version of presentism that involves thisnesses of past and present entities and I argue this view solves important problems facing standard versions of presentism.
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  40. Demystifying Emergence.David Yates - 2016 - Ergo: An Open Access Journal of Philosophy 3:809-841.
    Are the special sciences autonomous from physics? Those who say they are need to explain how dependent special science properties could feature in irreducible causal explanations, but that’s no easy task. The demands of a broadly physicalist worldview require that such properties are not only dependent on the physical, but also physically realized. Realized properties are derivative, so it’s natural to suppose that they have derivative causal powers. Correspondingly, philosophical orthodoxy has it that if we want special science properties to (...)
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  41. Leibniz and the Stoics: Fate, Freedom, and Providence.David Forman - 2015 - In John Sellars (ed.), The Routledge Handbook of the Stoic Tradition. New York: Routledge. pp. 226-242.
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  42. A probabilistic analysis of argument cogency.David Godden & Frank Zenker - 2018 - Synthese 195 (4):1715-1740.
    This paper offers a probabilistic treatment of the conditions for argument cogency as endorsed in informal logic: acceptability, relevance, and sufficiency. Treating a natural language argument as a reason-claim-complex, our analysis identifies content features of defeasible argument on which the RSA conditions depend, namely: change in the commitment to the reason, the reason’s sensitivity and selectivity to the claim, one’s prior commitment to the claim, and the contextually determined thresholds of acceptability for reasons and for claims. Results contrast with, and (...)
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  43. The Stony Metaphysical Heart of Animalism.David Shoemaker - 2016 - In Stephan Blatti & Paul F. Snowdon (eds.), Animalism: New Essays on Persons, Animals, and Identity. Oxford, GB: Oxford University Press UK. pp. 303-328.
    Animalism—the view that the identity across time of individuals like us consists in the persistence of our animal organisms—does poorly at accounting for our identity-related practical concerns. The reason is straightforward: whereas our practical concerns seem to track the identity of psychological creatures—persons—animalism focuses on the identity of human organisms who are not essentially persons. This lack of fit between our practical concerns and animalism has been taken to reduce animalism’s plausibility (relative to psychological criteria of identity). In this paper, (...)
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  44. From punishment to universalism.David Rose & Shaun Nichols - 2018 - Mind and Language 34 (1):59-72.
    Many philosophers have claimed that the folk endorse moral universalism. Some have taken the folk view to support moral universalism; others have taken the folk view to reflect a deep confusion. And while some empirical evidence supports the claim that the folk endorse moral universalism, this work has uncovered intra-domain differences in folk judgments of moral universalism. In light of all this, our question is: why do the folk endorse moral universalism? Our hypothesis is that folk judgments of moral universalism (...)
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  45. Responsibility Without Identity.David Shoemaker - 2012 - The Harvard Review of Philosophy 18 (1):109-132.
    Many people believe that for someone to now be responsible for some past action, the agent of that action and the responsible agent now must be one and the same person. In other words, many people that moral responsibility presupposes numerical personal identity. In this paper, I show why this platitude is false. I then suggest an account of what actual metaphysical relationship moral responsibility presupposes instead.
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  46. Sentient Nonpersons and the Disvalue of Death.David DeGrazia - 2016 - Bioethics 30 (7):511-519.
    Implicit in our everyday attitudes and practices is the assumption that death ordinarily harms a person who dies. A far more contested matter is whether death harms sentient individuals who are not persons, a category that includes many animals and some human beings. On the basis of the deprivation account of the harm of death, I argue that death harms sentient nonpersons. I next consider possible bases for the commonsense judgment that death ordinarily harms persons more than it harms sentient (...)
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  47. Methodological moralism in political philosophy.David Estlund - 2017 - Critical Review of International Social and Political Philosophy 20 (3):385-402.
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  48. The Physical Action Theory of Trying.David-Hillel Ruben - 2015 - Methode 4 (6).
    Metaphysically speaking, just what is trying? There appear to be two options: to place it on the side of the mind or on the side of the world. Volitionists, who think that to try is to engage in a mental act, perhaps identical to willing and perhaps not, take the mind-side option. The second, or world-side option identifies trying to do something with one of the more basic actions by which one tries to do that thing. The trying is then (...)
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  49. Transdisciplinary Philosophy of Science: Meeting the Challenge of Indigenous Expertise.David Ludwig, Charbel El-Hani, Fabio Gatti, Catherine Kendig, Matthias Kramm, Lucia Neco, Abigail Nieves Delgado, Luana Poliseli, Vitor Renck, Adriana Ressiore C., Luis Reyes-Galindo, Thomas Loyd Rickard, Gabriela De La Rosa, Julia J. Turska, Francisco Vergara-Silva & Rob Wilson - 2024 - Philosophy of Science 91:1221-1231.
    Transdisciplinary research knits together knowledge from diverse epistemic communities in addressing social-environmental challenges, such as biodiversity loss, climate crises, food insecurity, and public health. This paper reflects on the roles of philosophy of science in transdisciplinary research while focusing on Indigenous and other subaltern forms of knowledge. We offer a critical assessment of demarcationist approaches in philosophy of science and outline a constructive alternative of transdisciplinary philosophy of science. While a demarcationist focus obscures the complex relations between epistemic communities, transdisciplinary (...)
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  50. The priority view.David McCarthy - 2017 - Economics and Philosophy 33 (2):215–57.
    According to the priority view, or prioritarianism, it matters more to benefit people the worse off they are. But how exactly should the priority view be defined? This article argues for a highly general characterization which essentially involves risk, but makes no use of evaluative measurements or the expected utility axioms. A representation theorem is provided, and when further assumptions are added, common accounts of the priority view are recovered. A defense of the key idea behind the priority view, the (...)
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