Results for 'David Diehl'

954 found
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  1. Novel sequence feature variant type analysis of the HLA genetic association in systemic sclerosis.R. Karp David, Marthandan Nishanth, G. E. Marsh Steven, Ahn Chul, C. Arnett Frank, S. DeLuca David, D. Diehl Alexander, Dunivin Raymond, Eilbeck Karen, Feolo Michael & Barry Smith - 2009 - Human Molecular Genetics 19 (4):707-719.
    Significant associations have been found between specific human leukocyte antigen (HLA) alleles and organ transplant rejection, autoimmune disease development, and the response to infection. Traditional searches for disease associations have conventionally measured risk associated with the presence of individual HLA alleles. However, given the high level of HLA polymorphism, the pattern of amino acid variability, and the fact that most of the HLA variation occurs at functionally important sites, it may be that a combination of variable amino acid sites shared (...)
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  2. OBO Foundry in 2021: Operationalizing Open Data Principles to Evaluate Ontologies.Rebecca C. Jackson, Nicolas Matentzoglu, James A. Overton, Randi Vita, James P. Balhoff, Pier Luigi Buttigieg, Seth Carbon, Melanie Courtot, Alexander D. Diehl, Damion Dooley, William Duncan, Nomi L. Harris, Melissa A. Haendel, Suzanna E. Lewis, Darren A. Natale, David Osumi-Sutherland, Alan Ruttenberg, Lynn M. Schriml, Barry Smith, Christian J. Stoeckert, Nicole A. Vasilevsky, Ramona L. Walls, Jie Zheng, Christopher J. Mungall & Bjoern Peters - 2021 - BioaRxiv.
    Biological ontologies are used to organize, curate, and interpret the vast quantities of data arising from biological experiments. While this works well when using a single ontology, integrating multiple ontologies can be problematic, as they are developed independently, which can lead to incompatibilities. The Open Biological and Biomedical Ontologies Foundry was created to address this by facilitating the development, harmonization, application, and sharing of ontologies, guided by a set of overarching principles. One challenge in reaching these goals was that the (...)
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  3. (1 other version)Epistemology of disagreement: The good news.David Christensen - 2007 - Philosophical Review 116 (2):187-217.
    How should one react when one has a belief, but knows that other people—who have roughly the same evidence as one has, and seem roughly as likely to react to it correctly—disagree? This paper argues that the disagreement of other competent inquirers often requires one to be much less confident in one’s opinions than one would otherwise be.
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  4. Humean Rationalism.David Builes - 2024 - Philosophical Studies 181 (10):2563-2576.
    According to the Principle of Sufficient Reason, every fact has an explanation. An important challenge to this principle is that it risks being a counterexample to itself. What explains why everything needs to be explained? My first goal is to distinguish two broad kinds of answers to this question, which I call “Humean Rationalism” and “Non-Humean Rationalism”. My second goal will be to defend the prospects of Humean Rationalism.
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  5. (1 other version)Are we free to break the laws?David Lewis - 1981 - Theoria 47 (3):113-21.
    I insist that I was able to raise my hand, and I acknowledge that a law would have been broken had I done so, but I deny that I am therefore able to break a law. To uphold my instance of soft determinism, I need not claim any incredible powers. To uphold the compatibilism that I actually believe, I need not claim that such powers are even possible. My incompatibilist opponent is a creature of fiction, but he has his prototypes (...)
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  6. On distinguishing epistemic from pragmatic action.David Kirsh & Paul Maglio - 1994 - Cognitive Science 18 (4):513-49.
    We present data and argument to show that in Tetris - a real-time interactive video game - certain cognitive and perceptual problems are more quickly, easily, and reliably solved by performing actions in the world rather than by performing computational actions in the head alone. We have found that some translations and rotations are best understood as using the world to improve cognition. These actions are not used to implement a plan, or to implement a reaction; they are used to (...)
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  7. Virtue and Meaning: A Neo-Aristotelian Perspective.David McPherson - 2020 - Cambridge, UK: Cambridge University Press.
    The revival of Aristotelian virtue ethics can be seen as a response to the modern problem of disenchantment, that is, the perceived loss of meaning in modernity. However, in Virtue and Meaning, David McPherson contends that the dominant approach still embraces an overly disenchanted view. In a wide-ranging discussion, McPherson argues for a more fully re-enchanted perspective that gives better recognition to the meanings by which we live and after which we seek, and to the fact that human beings (...)
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  8. Consciousness is Underived Intentionality.David Bourget - 2010 - Noûs 44 (1):32 - 58.
    Representationalists argue that phenomenal states are intentional states of a special kind. This paper offers an account of the kind of intentional state phenomenal states are: I argue that they are underived intentional states. This account of phenomenal states is equivalent to two theses: first, all possible phenomenal states are underived intentional states; second, all possible underived intentional states are phenomenal states. I clarify these claims and argue for each of them. I also address objections which touch on a range (...)
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  9. Clever bookies and coherent beliefs.David Christensen - 1991 - Philosophical Review 100 (2):229-247.
    A critical examination of the Reflection principle in Bayesian epistemology, and of the diachronic Dutch-book-style arguments that have been invoked to support Reflection and Conditionalization.
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  10. Building Compressed Causal Models of the World.David Kinney & Tania Lombrozo - forthcoming - Cognitive Psychology.
    A given causal system can be represented in a variety of ways. How do agents determine which variables to include in their causal representations, and at what level of granularity? Using techniques from Bayesian networks, information theory, and decision theory, we develop a formal theory according to which causal representations reflect a trade-off between compression and informativeness, where the optimal trade-off depends on the decision-theoretic value of information for a given agent in a given context. This theory predicts that, all (...)
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  11. Exploitative informing.David Thorstad - forthcoming - British Journal for the Philosophy of Science.
    Informing others about the world is often a helpful act. In this paper, I study agents who conduct experiments to gather information about the world, committing in advance to fully disclose the nature of the experiment together with all experimental findings. While this appears to be a benign activity, I characterize a type of exploitative informing that is possible even within this restricted setup. I show how exploitative informants use public experiments to predictably manipulate interlocutors’ beliefs and actions to their (...)
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  12. Measuring confirmation.David Christensen - 1999 - Journal of Philosophy 96 (9):437-461.
    The old evidence problem affects any probabilistic confirmation measure based on comparing pr(H/E) and pr(H). The article argues for the following points: (1) measures based on likelihood ratios also suffer old evidence difficulties; (2) the less-discussed synchronic old evidence problem is, in an important sense, the most acute; (3) prominent attempts to solve or dissolve the synchronic problem fail; (4) a little-discussed variant of the standard measure avoids the problem, in an appealing way; and (5) this measure nevertheless reveals a (...)
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  13. Full information accounts of well-being.David Sobel - 1994 - Ethics 104 (4):784-810.
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  14. Dissolving the moral-conventional distinction.David C. Sackris - 2024 - Philosophical Psychology.
    One way in which philosophers have often sought to distinguish moral judgments from non-moral judgments is by using the “moral-conventional” distinction. I seek to raise serious questions about the significance of the moral-conventional distinction, at least for philosophers interested in moral judgment. I survey recent developments in the fields of philosophy, psychology, and cognitive science that have led many to the conclusion that moral judgment is not a distinctive kind of judgment or the result of a specific, identifiable cognitive process. (...)
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  15. Rational dynamics in efficient inquiry.David Barack - forthcoming - Analysis.
    Which premisses should we use to start our inquiries? Which transitions during inquiry should we take next? When should we switch lines of inquiry? In this paper, I address these open questions about inquiry, formulating novel norms for such decisions during deductive reasoning. I use the first-order predicate calculus, in combination with Carnap’s state description framework, to state such norms. Using that framework, I first demonstrate some properties of sets of sentences used in deduction. I then state some norms for (...)
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  16. Explanationism about Freedom and Orthonomy.David Heering - forthcoming - Journal of Philosophy.
    According to a popular idea, freedom is grounded in orthonomy – the ability to be responsive to normative demands. But how exactly must an agent’s action relate to their reasons in order for this orthonomous relationship to hold? In this paper, I propose a novel explanationist answer to this question. I argue that extant answers – causalism and modalism about orthonomy – fail because they fail to account for the fact that intuitions about freedom and orthonomy track facts about explanation. (...)
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  17. How Are Basic Belief-Forming Methods Justified?David Enoch & Joshua Schechter - 2008 - Philosophy and Phenomenological Research 76 (3):547–579.
    In this paper, we develop an account of the justification thinkers have for employing certain basic belief-forming methods. The guiding idea is inspired by Reichenbach's work on induction. There are certain projects in which thinkers are rationally required to engage. Thinkers are epistemically justified in employing any belief-forming method such that "if it doesn't work, nothing will" for successfully engaging in such a project. We present a detailed account based on this intuitive thought and address objections to it. We conclude (...)
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  18. (1 other version)Lifeworld, Place, and Phenomenology: Holistic and Dialectical Perspectives.David Seamon - 2024 - Journal of Philosophical Investigations at University of Tabriz 18 (48):31-52.
    In this article, I clarify the phenomenological concept of lifeworld by drawing on the geographical themes of place, place experience, and place meaning. Most simply, lifeworld refers to a person or group’s day-to-day, taken-for-granted experience that typically goes unnoticed. One aim of phenomenological research is to examine the lifeworld as a means to identify and clarify the tacit, unnoticed aspects of human life so that they can be accounted for theoretically and practically. Here, I discuss some key phenomenological principles and (...)
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  19. Debate: Liberalism, equality, and fraternity in Cohen's critique of Rawls.David Estlund - 1998 - Journal of Political Philosophy 6 (1):99–112.
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  20. Why AIs Cannot Play Games.David Koepsell - manuscript
    This paper explores the human experience of game-playing and its implications for artificial intelligence. The author uses phenomenology to examine game-playing from a human-centered perspective and applies it to language games played by artificial intelligences and humans. The paper argues that AI cannot truly play games because it lacks the intentionality, embodied experience, and social interaction that are fundamental to human game-playing. Furthermore, current AI lacks the ability to converse, which is argued to be equivalent to Wittgenstein’s view of engaging (...)
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  21. The insularity of the reasonable: Why political liberalism must admit the truth.David Estlund - 1998 - Ethics 108 (2):252-275.
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  22. The impotence of the demandingness objection.David Sobel - 2007 - Philosophers' Imprint 7:1-17.
    Consequentialism, many philosophers have claimed, asks too much of us to be a plausible ethical theory. Indeed, the theory's severe demandingness is often claimed to be its chief flaw. My thesis is that as we come to better understand this objection, we see that, even if it signals or tracks the existence of a real problem for Consequentialism, it cannot itself be a fundamental problem with the view. The objection cannot itself provide good reason to break with Consequentialism, because it (...)
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  23. On following orders in an unjust war.David Estlund - 2007 - Journal of Political Philosophy 15 (2):213–234.
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  24. Conservatism in epistemology.David Christensen - 1994 - Noûs 28 (1):69-89.
    A wide range of prominent epistemological theories include a principle of conservatism. Such principles take the fact that an agent currently holds a certain belief to constitute at least some measure of epistemic justification for her to maintain that belief. I examine the main arguments that have been made in conservatism's behalf, and find them unsound. Most interestingly, conservatism does not fall out of confirmational holism (the view that the justification of each of our beliefs is in part determined by (...)
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  25. Two construals of Hempel’s dilemma: a challenge to physicalism, not dualism.David Buzaglo - 2024 - European Journal for Philosophy of Science 14 (2):1-17.
    In a recent paper, Firt, Hemmo and Shenker argue that Hempel’s dilemma, typically thought to primarily undermine physicalism, is generalizable and impacts mind-body dualism and many other theories equally. I challenge this view and argue that Hempel’s dilemma admits of at least two distinct construals: a general-skeptical construal, underpinned by historically driven arguments such as the pessimistic induction, and a non-skeptical construal, driven by the specific puzzles and volatility of current physics. While the general-skeptical construal applies to all changeable deep-structure (...)
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  26. When Words Speak Louder Than Actions: Delusion, Belief, and the Power of Assertion.David Rose, Wesley Buckwalter & John Turri - 2014 - Australasian Journal of Philosophy (4):1-18.
    People suffering from severe monothematic delusions, such as Capgras, Fregoli, or Cotard patients, regularly assert extraordinary and unlikely things. For example, some say that their loved ones have been replaced by impostors. A popular view in philosophy and cognitive science is that such monothematic delusions aren't beliefs because they don't guide behaviour and affect in the way that beliefs do. Or, if they are beliefs, they are somehow anomalous, atypical, or marginal beliefs. We present evidence from five studies that folk (...)
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  27. The Perniciousness of Higher-Order Evidence on Aesthetic Appreciation.Sackris David & Larsen Rasmus - 2023 - Dialogue:1-20.
    We demonstrate that many philosophers accept the following claim: When an aesthetic object is apprehended correctly, taking pleasure in said object is a reliable sign that the object is aesthetically successful. We undermine this position by showing that what grounds our pleasurable experience is opaque: In many cases, the experienced pleasure is attributable to factors that have little to do with the aesthetic object. The evidence appealed to is a form of Higher-Order Evidence (HOE) and we consider attempts to overcome (...)
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  28. Quine, Putnam, and the ‘Quine–Putnam’ Indispensability Argument.David Liggins - 2008 - Erkenntnis 68 (1):113 - 127.
    Much recent discussion in the philosophy of mathematics has concerned the indispensability argument—an argument which aims to establish the existence of abstract mathematical objects through appealing to the role that mathematics plays in empirical science. The indispensability argument is standardly attributed to W. V. Quine and Hilary Putnam. In this paper, I show that this attribution is mistaken. Quine's argument for the existence of abstract mathematical objects differs from the argument which many philosophers of mathematics ascribe to him. Contrary to (...)
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  29. Dutch-book arguments depragmatized: Epistemic consistency for partial believers.David Christensen - 1996 - Journal of Philosophy 93 (9):450-479.
    The most immediately appealing model for formal constraints on degrees of belief is provided by probability theory, which tells us, for instance, that the probability of P can never be greater than that of (P v Q). But while this model has much intuitive appeal, many have been concerned to provide arguments showing that ideally rational degrees of belief would conform to the calculus of probabilities. The arguments most frequently used to make this claim plausible are the so-called "Dutch Book" (...)
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  30. Intentional Psychologism.David Pitt - 2009 - Philosophical Studies 146 (1):117-138.
    In the past few years, a number of philosophers ; Horgan and Tienson 2002; Pitt 2004) have maintained the following three theses: there is a distinctive sort of phenomenology characteristic of conscious thought, as opposed to other sorts of conscious mental states; different conscious thoughts have different phenomenologies; and thoughts with the same phenomenology have the same intentional content. The last of these three claims is open to at least two different interpretations. It might mean that the phenomenology of a (...)
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  31. Morality and virtue: An assessment of some recent work in virtue ethics.David Copp & David Sobel - 2004 - Ethics 114 (3):514-554.
    This essay focuses on three recent books on morality and virtue, Michael Slote's 'Morals from Motives', Rosalind Hursthouse's 'On Virtue Ethics', and Philippa Foot's 'Natural Goodness'. Slote proposes an "agent-based" ethical theory according to which the ethical status of acts is derivative from assessments of virtue. Following Foot's lead, Hursthouse aims to vindicate an ethical naturalism that explains human goodness on the basis of views about human nature. Both Hursthouse and Slote take virtue to be morally basic in a way (...)
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  32. Moral responsibility and buffered alternatives.David P. Hunt - 2005 - Midwest Studies in Philosophy 29 (1):126–145.
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  33. Self to self.David Velleman - 1996 - Philosophical Review 105 (1):39-76.
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  34. Confirmational holism and bayesian epistemology.David Christensen - 1992 - Philosophy of Science 59 (4):540-557.
    Much contemporary epistemology is informed by a kind of confirmational holism, and a consequent rejection of the assumption that all confirmation rests on experiential certainties. Another prominent theme is that belief comes in degrees, and that rationality requires apportioning one's degrees of belief reasonably. Bayesian confirmation models based on Jeffrey Conditionalization attempt to bring together these two appealing strands. I argue, however, that these models cannot account for a certain aspect of confirmation that would be accounted for in any adequate (...)
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  35. Testimony, memory and the limits of the a priori.David Christensen & Hilary Kornblith - 1997 - Philosophical Studies 86 (1):1-20.
    A number of philosophers, from Thomas Reid1 through C. A. J. Coady2, have argued that one is justified in relying on the testimony of others, and furthermore, that this should be taken as a basic epistemic presumption. If such a general presumption were not ultimately dependent on evidence for the reliability of other people, the ground for this presumption would be a priori. Such a presumption would then have a status like that which Roderick Chisholm claims for the epistemic principle (...)
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  36. Is there a good epistemological argument against platonism?David Liggins - 2006 - Analysis 66 (2):135–141.
    Platonism in the philosophy of mathematics is the doctrine that there are mathematical objects such as numbers. John Burgess and Gideon Rosen have argued that that there is no good epistemological argument against platonism. They propose a dilemma, claiming that epistemological arguments against platonism either rely on a dubious epistemology, or resemble a dubious sceptical argument concerning perceptual knowledge. Against Burgess and Rosen, I show that an epistemological anti- platonist argument proposed by Hartry Field avoids both horns of their dilemma.
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  37. (1 other version)Forms of Luminosity: Epistemic Modality and Hyperintensionality in Mathematics.David Elohim - 2017 - Dissertation, Arché, University of St Andrews
    This book concerns the foundations of epistemic modality and hyperintensionality and their applications to the philosophy of mathematics. David Elohim examines the nature of epistemic modality, when the modal operator is interpreted as concerning both apriority and conceivability, as well as states of knowledge and belief. The book demonstrates how epistemic modality and hyperintensionality relate to the computational theory of mind; metaphysical modality and hyperintensionality; the types of mathematical modality and hyperintensionality; to the epistemic status of large cardinal axioms, (...)
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  38. Lying, liars and language.David Simpson - 1992 - Philosophy and Phenomenological Research 52 (3):623-639.
    This paper considers the phenomenon of lying and the implications it has for those subjects who are capable of lying. It is argued that lying is not just intentional untruthfulness, but is intentional untruthfulness plus an insincere invocation of trust. Understood in this way, lying demands of liars a sophistication in relation to themselves, to language, and to those to whom they lie which exceeds the demands on mere truth-tellers.
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  39. Truthmakers and explanation.David Liggins - 2005 - In Helen Beebee & Julian Dodd (eds.), Truthmakers: The Contemporary Debate. Oxford, GB: Clarendon Press. pp. 105--115.
    Truthmaker theory promises to do some useful philosophical work: equipping us to argue against phenomenalism and Rylean behaviourism, for instance, and helping us decide what exists (Lewis 1999, 207; Armstrong 1997, 113-119). But it has proved hard to formulate a truthmaker theory that is both useful and believable. I want to suggest that a neglected approach to truthmakers – that of Ian McFetridge – can surmount some of the problems that make other theories of truthmaking unattractive. To begin with, I’ll (...)
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  40. You are simple.David Barnett - 2010 - In Robert C. Koons & George Bealer (eds.), The waning of materialism. New York: Oxford University Press. pp. 161--174.
    I argue that, unlike your brain, you are not composed of other things: you are simple. My argument centers on what I take to be an uncontroversial datum: for any pair of conscious beings, it is impossible for the pair itself to be conscious. Consider, for instance, the pair comprising you and me. You might pinch your arm and feel a pain. I might simultaneously pinch my arm and feel a qualitatively identical pain. But the pair we form would not (...)
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  41. Varieties of hedonism.David Sobel - 2002 - Journal of Social Philosophy 33 (2):240–256.
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  42. Democracy without preference.David M. Estlund - 1990 - Philosophical Review 99 (3):397-423.
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  43. Diachronic coherence versus epistemic impartiality.David Christensen - 2000 - Philosophical Review 109 (3):349-371.
    It is obvious that we would not want to demand that an agent' s beliefs at different times exhibit the same sort of consistency that we demand from an agent' s simultaneous beliefs; there' s nothing irrational about believing P at one time and not-P at another. Nevertheless, many have thought that some sort of coherence or stability of beliefs over time is an important component of epistemic rationality.
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  44. The Listening Self: Personal Growth, Social Change and the Closure of Metaphysics.David Michael Levin - 1989 - Routledge.
    In a study that goes beyond the ego affirmed by Freudian psychology, David Levin offers an account of personal growth and self-fulfillment based on the development of our capacity for listening. Drawing on the work of Dewey, Piaget, Erikson, and Kohlberg, he uses the vocabulary of phenomenological psychology to distinguish four stages in this developmental process and brings us the significance of these stages for music, psychotherapy, ethics, politics, and ecology. This analysis substantiates his claim that the development of (...)
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  45. Glymour on evidential relevance.David Christensen - 1983 - Philosophy of Science 50 (3):471-481.
    Glymour's "bootstrap" account of confirmation is designed to provide an analysis of evidential relevance, which has been a serious problem for hypothetico-deductivism. As set out in Theory and Evidence, however, the "bootstrap" condition allows confirmation in clear cases of evidential irrelevance. The difficulties with Glymour's account seem to be due to a basic feature which it shares with hypothetico-deductive accounts, and which may explain why neither can give a satisfactory analysis of evidential relevance.
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  46. The metaphysics of the social world.David-Hillel Ruben - 1985 - London: Routledge & Kegan Paul.
    A careful elaboration and defence of holism in the philosophy of the social sciences, with regard both to particulars and properties. The last chapter addresses the issue of the irreducibility of holistic explanation in the social sciences.
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  47. Does colour constancy exist?David H. Foster - 2003 - Trends in Cognitive Sciences 7 (10):439-443.
    For a stable visual world, the colours of objects should appear the same under different lights. This property of colour constancy has been assumed to be fundamental to vision, and many experimental attempts have been made to quantify it. I contend here, however, that the usual methods of measurement are either too coarse or concentrate not on colour constancy itself, but on other, complementary aspects of scene perception. Whether colour constancy exists other than in nominal terms remains unclear.
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  48. Nihilism without Self-Contradiction.David Liggins - 2008 - Royal Institute of Philosophy Supplement 62:177-196.
    in Robin Le Poidevin (ed.) Being: Developments in Contemporary Metaphysics. Cambridge: Cambridge University Press. Peter van Inwagen claims that there are no tables or chairs. He also claims that sentences such as ‘There are chairs here’, which seem to imply their existence, are often true. This combination of views opens van Inwagen to a charge of self-contradiction. I explain the charge, and van Inwagen’s response to it, which involves the claim that sentences like ‘There are tables’ shift their truth-conditions between (...)
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  49. Shepherd’s Claim that Sensations Are too Fleeting to Stand in Causal Relations with Other Sensations.David Landy - forthcoming - Journal of Scottish Philosophy.
    Shepherd argues that we can know that there exists a universe external to the mind because that universe is the only possible cause of our sensations. As a part of that argument, Shepherd eliminates the possibility that sensations might be caused by other sensations on the grounds that sensations are merely momentary existences and so not capable of standing in causal relations with each other. And yet she claims that sensations do stand in causal relations to other objects, both as (...)
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  50. Collective nouns and the distribution problem.David Nicolas & Jonathan D. Payton - forthcoming - Synthese.
    Intuitively, collective nouns are pseudo-singular: a collection of things (a pair of people, a flock of birds, etc.) just is the things that make ‘it’ up. But certain facts about natural language seem to count against this view. In short, distributive predicates and numerals interact with collective nouns in ways that they seemingly shouldn’t if those nouns are pseudo-singular. We call this set of issues ‘the distribution problem’. To solve it, we propose a modification to cover-based semantics. On this semantics, (...)
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