Kolloquiumsbeiträge des XV. Deutschen Kongresses für Philosophie 1990 in Hamburg. Mit Beiträgen von Herbert Schnädelbach, Hilary Putnam, Karl-Otto Apel, Walter Ch. Zimmerli, Rudolf A. Makkreel, Wolfgang Bartuschat, Elke Hahn und Klaus Vieweg, Roland Simon-Schaefer, Ruedi Imbach, Georg Wieland, Jan Peter Beckmann, Pierre Aubenque, Annemarie Gethmann-Siefert, Gernot Böhme, Dietrich Böhler, Jürgen Habermas, Friedrich Kambartel, Oswald Schwemmer, Dieter Birnbacher, Karl-Friedrich Wessel, Friedrich Rapp, Otfried Höffe, Henning Ottmann und Terry Pinkard.

Some have objected to human enhancement on the grounds that it violates the autonomy of the enhanced. These objections, however, overlook the interesting possibility that autonomy itself could be enhanced. How, exactly, to enhance autonomy is a difficult problem due to the numerous and diverse accounts of autonomy in the literature. Existing accounts of autonomy enhancement rely on narrow and controversial conceptions of autonomy. However, we identify one feature of autonomy common to many mainstream accounts: reasoning ability. Autonomy can then (...) be enhanced by improving people’s reasoning ability, in particular through cognitive enhancement; given how valuable autonomy is usually taken to be, this gives us extra reason to pursue such cognitive enhancements. Moreover, autonomy-based objections will be especially weak against such enhancements. As we will argue, those who are worried that enhancements will inhibit people’s autonomy should actually embrace those enhancements that will improve autonomy. (shrink)

The current prevailing view is that participation in biomedical research is above and beyond the call of duty. While some commentators have offered reasons against this, we propose a novel public goods argument for an obligation to participate in biomedical research. Biomedical knowledge is a public good, available to any individual even if that individual does not contribute to it. Participation in research is a critical way to support an important public good. Consequently, all have a duty to participate. The (...) current social norm is that individuals participate only if they have a good reason to do so. The public goods argument implies that individuals should participate unless they have a good reason not to. Such a shift would be of great aid to the progress of biomedical research, eventually making society significantly healthier and longer lived. (shrink)

While philosophers are often concerned with the conditions for moral knowledge or justification, in practice something arguably less demanding is just as, if not more, important – reliably making correct moral judgments. Judges and juries should hand down fair sentences, government officials should decide on just laws, members of ethics committees should make sound recommendations, and so on. We want such agents, more often than not and as often as possible, to make the right decisions. The purpose of this paper (...) is to propose a method of enhancing the moral reliability of such agents. In particular, we advocate for a procedural approach; certain internal processes generally contribute to people’s moral reliability. Building on the early work of Rawls, we identify several particular factors related to moral reasoning that are specific enough to be the target of practical intervention: logical competence, conceptual understanding, empirical competence, openness, empathy and bias. Improving on these processes can in turn make people more morally reliable in a variety of contexts and has implications for recent debates over moral enhancement. (shrink)

Moral enhancement is an ostensibly laudable project. Who wouldn’t want people to become more moral? Still, the project’s approach is crucial. We can distinguish between two approaches for moral enhancement: direct and indirect. Direct moral enhancements aim at bringing about particular ideas, motives or behaviors. Indirect moral enhancements, by contrast, aim at making people more reliably produce the morally correct ideas, motives or behaviors without committing to the content of those ideas, motives and/or actions. I will argue, on Millian grounds, (...) that the value of disagreement puts serious pressure on proposals for relatively widespread direct moral enhancement. A more acceptable path would be to focus instead on indirect moral enhancements while staying neutral, for the most part, on a wide range of substantive moral claims. I will outline what such indirect moral enhancement might look like, and why we should expect it to lead to general moral improvement. (shrink)

The COVID-19 pandemic revealed numerous weaknesses in pandemic preparedness and response, including underfunding, inadequate surveillance, and inequitable distribution of countermeasures. To overcome these weaknesses for future pandemics, WHO released a zero draft of a pandemic treaty in February, 2023, and subsequently a revised bureau's text in May, 2023. COVID-19 made clear that pandemic prevention, preparedness, and response reflect choices and value judgements. These decisions are therefore not a purely scientific or technical exercise, but are fundamentally grounded in ethics. The latest (...) treaty draft reflects these ethical considerations by including a section entitled Guiding Principles and Approaches. Most of these principles are ethical—they establish core values that undergird the treaty. Unfortunately, the treaty draft's set of principles are numerous, overlapping, and show inadequate coherence and consistency. We propose two improvements to this section of the draft pandemic treaty. First, key guiding ethical principles should be clearer and more precise than they currently are. Second, the link between ethical principles and policy implementation should be clearly established and define boundaries on acceptable interpretation, ensuring that signatories abide by these principles. (shrink)

The prospect of consumable meat produced in a laboratory setting without the need to raise and slaughter animals is both realistic and exciting. Not only could such in vitro meat become popular due to potential cost savings, but it also avoids many of the ethical and environmental problems with traditional meat productions. However, as with any new technology, in vitro meat is likely to face some detractors. We examine in detail three potential objections: 1) in vitro meat is disrespectful, either (...) to nature or to animals; 2) it will reduce the number of happy animals in the world; and 3) it will open the door to cannibalism. While each objection has some attraction, we ultimately find that all can be overcome. The upshot is that in vitro meat production is generally permissible and, especially for ethical vegetarians, worth promoting. (shrink)

It has recently been argued that reproductive genetic manipulation technologies like mitochondrial replacement and germline CRISPR modifications cannot be said to save anyone’s life because, counterfactually, no one would suffer more or die sooner absent the intervention. The present article argues that, on the contrary, reproductive genetic manipulations may be life-saving (and, from this, have therapeutic value) under an appropriate population health perspective. As such, popular reports of reproductive genetic manipulations potentially saving lives or preventing disease are not necessarily mistaken, (...) though such terminology still requires further empirical validation. (shrink)

It is generally unquestioned that human subjects research review boards should assess the ethical acceptability of protocols. It says so right on the tin, after all: they are explicitly called research ethics committees in the UK. But it is precisely those sorts of unchallenged assumptions that should, from time to time, be assessed and critiqued, in case they are in fact unfounded. John Stuart Mill's objection to suppressers of dissent is instructive here: “If the opinion is right, they are deprived (...) of the opportunity of exchanging error for truth: if wrong, they lose, what is almost as great a benefit, the clearer perception and livelier impression of truth, produced by its collision with error”.1 Andrew Moore and Andrew Donnelly's compelling article, “The job of ‘ethics committees’”, is just this sort of challenge to conventional wisdom, a rejection of the notion that review boards should be considering ethical matters at all.2 If true, we should be substantially reforming our research ethics policies. And if false, rebuttals would help strengthen and ground the otherwise unquestioned assumption of the role of ethics committees. As it happens, I will argue that their critiques fall into the second category. While mistaken, they present a valuable opportunity to clarify the role of ethics committees and their relationship to relevant codes. In particular, I will defend a hybrid account where codes have strict primacy, but leave significant room for review boards …. (shrink)

With the recent report of a live birth after use of Mitochondrial replacement therapy, sometimes called ‘Three-parent IVF’, the clinical application of the technique is fast becoming a reality. While the United Kingdom allows the procedure under regulatory scrutiny, it remains effectively outlawed in many other countries. We argue that such prohibitions may violate individuals’ procreative rights, grounded in individuals’ interest in genetic affinity. The interest in genetic affinity was recently endorsed by Singapore’s highest court, reflecting an emphasis on the (...) importance of biological ties found across the globe. We apply that reasoning to make the case for a right to ‘Three-parent IVF’. (shrink)

Background Several jurisdictions, including Singapore, Australia, New Zealand and most recently Ireland, have a public interest or public good criterion for granting waivers of consent in biomedical research using secondary health data or tissue. However, the concept of the public interest is not well defined in this context, which creates difficulties for institutions, institutional review boards and regulators trying to implement the criterion. Main text This paper clarifies how the public interest criterion can be defensibly deployed. We first explain the (...) ethical basis for requiring waivers to only be granted to studies meeting the public interest criterion, then explore how further criteria may be set to determine the extent to which a given study can legitimately claim to be in the public interest. We propose an approach that does not attempt to measure magnitude of benefit directly, but rather takes into account metrics that are more straightforward to apply. To ensure consistent and justifiable interpretation, research institutions and IRBs should also incorporate procedural features such as transparency and public engagement in determining which studies satisfy the public interest requirement. Conclusion The requirement of public interest for consent waivers in secondary biomedical research should be guided by well-defined criteria for systematic evaluation. Such a criteria and its application need to be periodically subject to intra-committee and intra-institution review, reflection, deliberation and amendment. (shrink)

Michael Hauskeller (“Reflections from a Troubled Stream: Giubliani and Minerva on ‘After-Birth Abortion’) has recently suggested that we should resist rationalist tendencies in moral discourse: “[I]s not all morality ultimately irrational? Even the most strongly held moral convictions can be shown to lack a rational basis.” (Hauskeller 2012, p. 18) Hauskeller was responding to Alberto Giubliani and Francesca Minverva’s (2012) recent defense of the permissibility of killing infants, but his anti-rationality arguments have wide-reaching implications. Yet pace Hauskeller, rationality is indeed (...) of crucial importance to any ethical argument. We should not abandon rationality for the sake of refuting one discomforting hypothesis; instead, rationality must be rigorously employed, here and elsewhere, in the search for the truth. (shrink)

Transzendental wird hier, abweichend von Kant, im Sinn transzendentaler Argumente verstanden. Im Kontext der Letztbegründungsdiskussion sind diese dadurch definiert, dass ihre Verneinung zu einem pragmatischen Widerspruch führt. Nun ist Hegels Philosophie auf die ‚logische Idee‘ gegründet, also auf die in Hegels Verständnis fundamentale dialektische Logik. Sein philosophischer Systementwurf hat dadurch, wie gezeigt wird, transzendentalen Charakter und schließt dementsprechend auch eine transzendentale Naturphilosophie ein. Gezeigt wird weiter, dass Grundbe- stimmungen der Natur, die üblicherweise einfach vorausgesetzt werden, in diesem Rahmen grundsätzlich erklärt (...) werden können: die Existenz der Natur und ihr (räumlich-zeitliches) Auseinandersein, ferner die Erkenn- barkeit der Natur, ihre Gesetzmäßigkeit, Kontingenz und immanente Idea- lisierungstendenz. Dass sich so auch konkrete Naturphänomene erschließen, wird an zwei Exempeln verdeutlicht: in der Begründung dimensionaler Raumstrukturen und in der Begründung des Relativitätsprinzips der Bewe- gung – letzteres mit der Pointe (im Sinn einer Philosophie der (speziellen) Relativitätstheorie), dass die Relativität der Körperbewegung und die Absolutheit der Lichtbewegung so als logisch zusammengehörende Momente kinematischer Relativität verstehbar werden. (shrink)

What corresponds to the present-day ‘transcendental-pragmatic’ concept of ultimate grounding in Hegel is his claim to absoluteness of the logic. Hegel’s fundamental intuition is that of a ‘backward going grounding’ obtaining the initially unproved presuppositions, thereby ‘wrapping itself into a circle’ – the project of the self-grounding of logic, understood as the self-explication of logic by logical means. Yet this is not about one of the multiple ‘logics’ which as formal constructs cannot claim absoluteness. It is rather a fundamental logic (...) that only makes logical textures possible at all and so owns transcendental character. The non-contradiction-principle is an example for this. Es- sential is that it is ‘under-cover-effcient’ as soon as meaningful concepts are used. Self-explication of the fundamental logic then means explicating its implicit under-cover validity, in fact by means of the fundamental logic itself. As is shown this is the affair of dialectic which thereby is to be understood as ultimate grounding of the fundamental logic. This is analyzed in detail using the example of the being/non-being-dialectic. As is demonstrated each explication step generates a new implicit issue and therewith a new explication-discrepancy inducing an antinomical structure that anew forwards the explication procedure. So this is entirely determined by itself. Decisive for the ultimate grounding argumentation is that thereby an objectively verifyable procedure is found, which is apparently possible only in a Hegelian framework. In contrast the immediate evidence of a speech act claimed by the transcendental-pragmatic position has only private character, which is grounding-theoretically irrelevant. (shrink)

The predominant view is that a study using health data is observational research and should require individual consent unless it can be shown that gaining consent is impractical. But recent arguments have been made that citizens have an ethical obligation to share their health information for research purposes. In our view, this obligation is sufficient ground to expand the circumstances where secondary use research with identifiable health information is permitted without explicit subject consent. As such, for some studies the Institutional (...) Review Board/Research Ethics Committee review process should not assess the practicality of gaining consent for data use. Instead the review process should focus on assessing the public good of the research, public engagement and transparency. (shrink)

Given the sordid history of injustices linking genetics to race and ethnicity, considerations of justice are central to ensuring the responsible development of precision medicine programmes around the world. While considerations of justice may be in tension with other areas of concern, such as scientific value or privacy, there are also tensions between different aspects of justice. This paper focuses on three particular aspects of justice relevant to this precision medicine: social justice, distributive justice and human rights. We describe the (...) implications of each for the use of race and ethnicity in precision medicine, and also how they intersect and potentially conflict with each another. By attending to these intersections, we aim to enrich and add nuance to debates over how best to proceed with precision medicine initiatives. (shrink)

First I argue that the prohibition of linguistic self-reference as a solution to the antinomy problem contains a pragmatic contradiction and is thus not only too restrictive, but just inconsistent (chap.1). Furthermore, the possibilities of non-restrictive strategies for antinomy avoidance are discussed, whereby the explicit inclusion of the – pragmatically presuposed – consistency requirement proves to be the optimal strategy (chap.2). The central question here is that about the actual reason for antinomic structures. It turns out to be a form (...) of negative self-conditioning (chap.3). This makes it necessary to clarify the status of negative concepts (chap.4). The generalization of these considerations (chap.5) leads to the actual analysis of the antinomic basic structure (chap.6): Decisively for the pragmatics of the concept is that it positively owns a meaning, so that positivity is always constituted by the concept qua concept. Thus a negative concept is characterized by a fundamental ambivalence: From a semantic point of view it has negative character, in its pragmatic status as a concept, however, it has positive character. If the meaning is especially that of a negative self-reference, the ambivalence leads to the antinomic constellation of a negative self-condition – that is the crux of the matter here! The concept thus possesses the property defined by it exactly when it does not possess it and vice versa. A closer analysis shows that the function of reflective structures for the occurrence of antinomies has to be judged much more differentiated than previous opinions suggest. Not only are four forms of reflectivity to be distinguished in this context – ontic, semantic, pragmatic reflectivity, and especially the form of negative self-condition; but it is also apparent that these are intertwined with each other in a way that is difficult to be understood. The astonishing variety of relationships associated with this makes the irritation that has always emanated from the antinomy problem appear more comprehensible. In the developed pragmatic perspective furtheron parallels to the structure of self-consciousness become visible (chap.7). I conclude with considerations about the significance of the antinomic structure for the problem of dialectics, especially for the synthesis formation of mutually exclusive terms (chap.8). ---------- Zunächst wird gezeigt, dass das Verbot sprachlicher Selbstreferenz als Lösung des Antinomienproblems einen pragmatischen Widerspruch enthält und damit nicht nur zu restriktiv, sondern geradezu inkonsistent ist (Kap.1). Ferner werden Möglichkeiten nicht-restriktiver Strategien zur Antinomienvermeidung diskutiert, wobei sich die explizite Einbindung der – pragmatisch präsupponierten – Konsistenzforderung als optimale Strategie erweist (Kap.2). Zentral ist hier die Frage nach dem eigentlichen Grund antinomischer Strukturen. Er erweist sich als eine Form von negativer Selbst-Bedingung (Kap.3). Dies nötigt zu einer Klärung des Status negativer Begriffe (Kap.4). Die Verallgemeinerung dieser Überlegungen (Kap.5) leitet über zur eigentlichen Analyse der antinomischen Grundstruktur (Kap.6): Entscheidend zur Pragmatik des Begriffs gehört, dass ihm eine Bedeutung positiv zukommt, sodass durch den Begriff qua Begriff stets auch Positivität konstituiert ist. Dadurch ist ein negativer Begriff durch eine prinzipielle Ambivalenz gekennzeichnet: In semantischer Hinsicht hat er negativen Charakter, in seinem pragmatischen Status als Begriff hingegen positiven Charakter. Ist die Bedeutung insbesondere die eines negativen Selbstbezugs, führt die Ambivalenz zur antinomischen Konstellation einer negativen Selbst-Bedingung – das ist hier der springende Punkt! Der Begriff besitzt so die durch ihn definierte Eigenschaft genau dann, wenn er sie nicht besitzt und umgekehrt. Die nähere Analyse zeigt, dass hierbei die Funktion reflexiver Strukturen für das Auftreten von Antinomien weitaus differenzierter zu beurteilen ist, als bisherige Auffassungen nahelegen. Nicht nur dass in diesem Kontext vier Formen von Reflexivität – ontische, semantische, pragmatische Reflexivität und insbesondere auch die Form negativer Selbstbedingung – unterschieden werden müssen; es zeigt sich auch, dass diese in schwer durchschaubarer Weise ineinander verschränkt sind. Die damit verbundene erstaunliche Beziehungsvielfalt läßt die Irritation, die seit je vom Antinomienproblem ausging, begreiflicher erscheinen. In der entwickelten pragmatischen Perspektive werden ferner Parallelen zur Struktur von Selbstbewußtsein sichtbar (Kap.7). Ich schließe mit Überlegungen zur Bedeutung der antinomischen Struktur für das Problem der Dialektik, insbesondere zur Synthesebildung einander ausschließender Bestimmungen (Kap.8). (shrink)

Volume 20, Issue 2, February 2020, Page 20-22.

[[[ (Here only the chapters 3 – 8, see *** ) First I argue that the prohibition of linguistic self-reference as a solution to the antinomy problem contains a pragmatic contradiction and is thus not only too restrictive, but just inconsistent (chap.1). Furthermore, the possibilities of non-restrictive strategies for antinomy avoidance are discussed, whereby the explicit inclusion of the – pragmatically presuposed – consistency requirement proves to be the optimal strategy (chap.2). ]]] The central question here is that about the (...) actual reason for antinomic structures. It turns out to be a form of negative self-conditioning (chap.3). This makes it necessary to clarify the status of negative concepts (chap.4). The generalization of these considerations (chap.5) leads to the actual analysis of the antinomic basic structure (chap.6): Decisively for the pragmatics of the concept is that it positively owns a meaning, so that positivity is always constituted by the concept qua concept. Thus a negative concept is characterized by a fundamental ambivalence: From a semantic point of view it has negative character, in its pragmatic status as a concept, however, it has positive character. If the meaning is especially that of a negative self-reference, the ambivalence leads to the antinomic constellation of a negative self-condition – that is the crux of the matter here! The concept thus possesses the property defined by it exactly when it does not possess it and vice versa. A closer analysis shows that the function of reflective structures for the occurrence of antinomies has to be judged much more differentiated than previous opinions suggest. Not only are four forms of reflectivity to be distinguished in this context – ontic, semantic, pragmatic reflectivity, and especially the form of negative self-condition; but it is also apparent that these are intertwined with each other in a way that is difficult to be understood. The astonishing variety of relationships associated with this makes the irritation that has always emanated from the antinomy problem appear more comprehensible. In the developed pragmatic perspective furtheron parallels to the structure of self-consciousness become visible (chap.7). I conclude with considerations about the significance of the antinomic structure for the problem of dialectics, especially for the synthesis formation of mutually exclusive terms (chap.8). (shrink)

The study ties in with former considerations concerning the problem of phenomenal perception of higher animals. Accordingly the phenomenal character, qualia included, results from the adjustment of perceptions to (typal) behavioral dispositions under the principle of self-preservation: an emergence phenomenon provided by the constitutive system unity of perception and behavior, here characterized as percept-act-system. Thereby the subject of behavior can be explained as an emergent instance of the – system-theoretically highest rank – percept-act-level. In terms of the principle of self-preservation (...) it subjects all sensations to an valuation. Perception thus gaining existential sense for the subject, a psychic sense-dimension is spanned which as such does not own physical but ideal character. Accessing Hegel this is further interpreted: Accordingly the ontological basis of this view is the lawfulness of nature, understood as the ideal essence underlying it. In virtue of this – basically Hegelian-type idealistic – conception the material being of nature always encloses the possibility of the psychic, according to that ideal substratum of nature. (shrink)

The future of health research will be characterised by three continuing trends: rising demand for health data; increasing impracticability of obtaining specific consent for secondary research; and decreasing capacity to effectively anonymise data. In this context, governments, clinicians and the research community must demonstrate that they can be responsible stewards of health data. IRBs and RECs sit at heart of this process because in many jurisdictions they have the capacity to grant consent waivers when research is judged to be of (...) particular value. However, several different terms are used to refer to this value, indicating a lack of conceptual clarity regarding the appropriate test for access to health data for research without consent. In this paper we do three things. First we describe the current confusion and instability in terminology relating to public interest in the context of consent waivers. Second we argue for harmonisation of terminology on the grounds of clarity, transparency and consistency. Third we argue that the term ‘public interest’ best reflects the normative work required to justify consent waivers because it is the broadest of the competing terms. ‘Public interest’ contains within its scope positive and negative implications of a study, as well as welfare, justice and rights considerations. In making this argument, we explain the normative basis for consent waivers, and provide a starting place for further discussion about the precise conditions in which a given study can be said to advance the public interest. Ipsos MORI study found that: … the public would be broadly happy with administrative data linking for research projects provided Those projects have social value, broadly defined. Data are de-identified. Data are kept secure. Businesses are not able to access the data for profit. (shrink)

Summary: Kant's characterization of organic entities by the principle of an inner, and that is to say, immanently natural and mind-independent purposiveness has continued to retain validity. Difficulties however exist for Kant's theory from the conditions of their realization. The following inquiry attempts to describe to what extent this difficulty has currently found a system-theoretical solution: The realizability of cyclical causal relationships proves itself here to be a fundamental prerequisite. The possibility for self-regulating systems thus consequently ensues. Decisive for the (...) cybernetical reconstructability of inner purposiveness is however the evidence that the principle of self-regulation - which has apparently been misunderstood in recent discussions (Jonas, Spaemann, Löw) includes not only the possibility of active goal pursuance (robots) but, additionally, the possibility forexistential self-reference (organism). This has fostered greater insight into how normative instances can be established upon a purely physical basis. The status of information will then accordingly be questioned. This inquiry closes with a look to possible ontological consequences. (shrink)

The center of this investigation is the ‘real hard problem’ of phenomenal perception (Chalmers), i.e. of the qualitative kind of perception presenting the subject with forms, colors, smell, pleasurable or negative feelings etc.; the problem of Human consciousness, however, will explicitly not be treated. The ‘explanatory gap’ (Levine) complained by the philosophy of mind, that is to say the failure of all attempts to supply a neuronal explanation of experiences, is emergence-theoretically treated: Systems own properties and laws different from their (...) components; so the emergence concept shows promise also for the explanatory potential with respect to neuronal systems. Here the phenomenal character of perception is explained from the systemic co-action of perception and behavior, whereby also an interpretation is opened to Davidson’s anomal monism. Qualitative feelings, as is further shown, are not to be understood as needless ‘epiphenomena’, but as a necessary completion of per-ception when, as in the case of higher animals, the behavior is primarily controlled by phenomenal perception. (shrink)

The well-known empiricist apories of the lawfulness of nature prevent an adequate philosophical interpretation of empirical science until this day. Clarification can only be expected through an immanent refutation of the empiricist point of view. My argument is that Hume’s claim, paradigmatic for modern empiricism, is not just inconsequent, but simply contradictory: Empiricism denies that a lawlike character of nature can be substantiated. But, as is shown, anyone who claimes experience to be the basis of knowledge (as the empiricist naturally (...) does), has, in fact, always already presupposed the lawfullness of nature, i.e. has assumed the ontology of a nature lawful in itself. If lawfulness is, more closely, understood as dependency on conditions, then the functional character of the laws of nature is involved with the consequence that verification is not to be taken as a mere repetition of measurements but as clarification of the conditional structure of the physical process. Furthermore the functionality of the laws of nature also includes a statement on their invariance (relative to certain transformations) and so their lawlikeness. This throws a new light on the problem of induction. Seen in this way it is hardly surprising that the notorious neglect of the functional aspect in empiricism has led to fundamental problems with the concept of the law of nature. (shrink)

The right to withdraw from participation in research is recognized in virtually all national and international guidelines for research on human subjects. It is therefore surprising that there has been little justification for that right in the literature. We argue that the right to withdraw should protect research participants from information imbalance, inability to hedge, inherent uncertainty, and untoward bodily invasion, and it serves to bolster public trust in the research enterprise. Although this argument is not radical, it provides a (...) useful way to determine how the right should be applied in various cases. (shrink)

Ethical decision-making frameworks assist in identifying the issues at stake in a particular setting and thinking through, in a methodical manner, the ethical issues that require consideration as well as the values that need to be considered and promoted. Decisions made about the use, sharing, and re-use of big data are complex and laden with values. This paper sets out an Ethics Framework for Big Data in Health and Research developed by a working group convened by the Science, Health and (...) Policy-relevant Ethics in Singapore Initiative. It presents the aim and rationale for this framework supported by the underlying ethical concerns that relate to all health and research contexts. It also describes a set of substantive and procedural values that can be weighed up in addressing these concerns, and a step-by-step process for identifying, considering, and resolving the ethical issues arising from big data uses in health and research. This Framework is subsequently applied in the papers published in this Special Issue. These papers each address one of six domains where big data is currently employed: openness in big data and data repositories, precision medicine and big data, real-world data to generate evidence about healthcare interventions, AI-assisted decision-making in healthcare, public-private partnerships in healthcare and research, and cross-sectoral big data. (shrink)

The Cartesian concept of nature, which has determined modern thinking until the present time, has become obsolete. It shall be shown that Hegel's objective-idealistic conception of nature discloses, in comparison to that of Descartes, new perspectives for the comprehension of nature and that this, in turn, results in possibilities of actualizing Hegel's philosophy of nature. If the argumentation concerning philosophy of nature is intended to catch up with the concrete Being-of-nature and to meet it in its concretion, then this is (...) impossible for the finite spirit in a strictly a priori sense – this is the thesis supported here which is not at all close to Hegel. As the argumentation rather has to consider the conditions of realization concerning the Being-of-nature, too, it is compelled to take up empirical elements – concerning the organism, for instance, system-theoretical aspects, physical and chemical features of the nervous system, etc. With that, on the one hand, empirical-scientific premises are assumed (e.g. the lawlikeness of nature), which on the other hand become (now close to Hegel) possibly able to be founded in the frame of a Hegelian-idealistic conception. In this sense, a double strategy of empirical-scientific concretization and objective-idealistic foundation is followed up, which represents the methodical basic principle of the developed considerations. In the course of the undertaking, the main aspects of the whole Hegelian design concerning the philosophy of nature are considered – space and time, mass and motion, force and law of nature, the organism, the pro-blem of evolution, psychic being – as well as Hegel's basic thesis concerning the philosophy of nature, that therein a tendency toward coherence and idealization manifests itself in the sense of a (categorically) gradually rising succession of nature: from the separateness of space to the ideality of sensation. In the sense of the double strategy of concretization and foundation it is shown that on the one hand possibilities of philosophical penetration concerning actual empirical-scientific results are opened, and on the other hand – in turn – a re-interpretation of Hegel's theorem on the basis of physical, evolution-theoretical and system-theoretical argumentation also becomes possible. In this mutual crossing-over and elucidation of empirical and Hegelian argumentation not only do perspectives of a new comprehension of nature become visible, but also, at the same time – as an essential consequence of this methodical principle – thoughts on the possibilities of actualizing Hegel's philosophy of nature. (shrink)

There are many treatises concerning the soul. Plato was not the first to write on the subject. From Greek philosophy and religion the soul wandered over to Christianity. According to this religion, the soul accompanies the body, which it inhabits for a short while in order to then return to its primary homeland embodied in areas of primary existence and truth. There are many treatises concerning the soul. Plato was not the first to write on the subject. Wisława Szymborska, in (...) her collection of poems published in 2002 and titled A Moment, poses the most essential questions: Why does man exist? Why isn’t there nothingness? She also asks: What is the soul? Does man really possess a soul? What is the relationship between man and soul – to whom does the soul really belong? This is a treatise in the form of a poem which appears to be plain and modest, yet the questions it asks are fundamental. This interpretation aims to develop and translate from the language of poetry the religious and philosophical questions embraced by Szymborska’s poem. (shrink)

The scope of my considerations here is defined along two lines, which seem to me of essential relevance for a theory of dialectic. On the one hand, the form of negation that – as self-referring antinomical negation – gains a quasi-semantic expulsory force [Sprengkraft] and therewith a forwarding [weiterverweisenden] character; on the other hand, the notion that every logical category is defective insofar as the explicit meaning of a category does not express everything that is already implicitly presupposed for its (...) meaning. Both lines are tightly interwoven. This I would like to demonstrate with the example of the dialectic of Being and Non-Being at the beginning of the Hegelian Logic. I will first make visible the basic structures of dialectical argumentation (sections II and III) – whereby certain revisions will turn out to be necessary in comparison with Hegel’s actual argument. Thereby it proves essential that the whole apparatus of logical categories and principles must be always already available and utilized for the dialectical explication: proving dialectic as a self-explication of logic by logical means: dialectic, as it were, as the self-fulfillment of logic (sections IV–VI). (shrink)

As opposed to a ‘one size fits all’ approach, precision medicine uses relevant biological, medical, behavioural and environmental information about a person to further personalize their healthcare. This could mean better prediction of someone’s disease risk and more effective diagnosis and treatment if they have a condition. Big data allows for far more precision and tailoring than was ever before possible by linking together diverse datasets to reveal hitherto-unknown correlations and causal pathways. But it also raises ethical issues relating to (...) the balancing of interests, viability of anonymization, familial and group implications, as well as genetic discrimination. This article analyses these issues in light of the values of public benefit, justice, harm minimization, transparency, engagement and reflexivity and applies the deliberative balancing approach found in theEthical Framework for Big Data in Health and Research to a case study on clinical genomic data sharing. Please refer to that article for an explanation of how this framework is to be used, including a full explanation of the key values involved and the balancing approach used in the case study at the end. Our discussion is meant to be of use to those involved in the practice as well as governance and oversight of precision medicine to address ethical concerns that arise in a coherent and systematic manner. (shrink)

My argument is that Chalmers' zombie fiction and his rigid-designator-argument going back on Kripke comes down to a petitio principii. Rather, at the core it appears to be more related to the essential 'privacy' of the phenomenal internal perspective. In return for Chalmers I argue that the 'principle self-preservation' of living organisms necessarily implies subjectivity and the emergence of sense. The comparison with a robot proves instructive. The mode of 'mere physical' being is transcended if, in the form of phenomenal (...) perception, sense appears on the stage of higher animals – a transition explained here as an emergence phenomenon based on the systemic co-operation of perception, valuation and action ('perc-val-act system'). Some fundamental considerations are added: Those consequences implied by the principle self-preservation reveal the natural-biological origin of the organism – primarily seeming a more insignificant circumstance – as a momentous fundamental difference (end-in-itself-character, subjectivity, constitution of sense) compared to technical artefacts (robot). And the emergentist approach indicates the – maybe paradoxical – possibility of a dualism of physical and psychical phenomena in an overall physical system, that is not dualistic at the same time. (shrink)

A strength of liberal political institutions is their ability to accommodate pluralism, both allowing divergent comprehensive doctrines as well as constructing the common ground necessary for diverse people to live together. A pressing question is how far such pluralism extends. Which comprehensive doctrines are simply beyond the pale and need not be accommodated by a political consensus? Rawls attempted to keep the boundaries of reasonable disagreement quite broad by infamously denying that political liberalism need make reference to the concept of (...) truth, a claim that has been criticized by Joseph Raz, Joshua Cohen, and David Estlund. In this paper, we argue that these criticisms fail due to the fact that political liberalism can remain non-committal on the nature of truth, leaving the concept of truth in the domain of comprehensive doctrines while still avoiding the issues raised by Raz, Cohen, and Estlund. Further substantiating this point is the fact that Rawls would, and should, include parties in the overlapping consensus whose views on truth may be incoherent. Once it is seen that political liberalism allows such incoherence to reasonable parties, it is clear that the inclusion of truth and the requirement of coherence urged by Raz, Cohen, and Estlund requires more of reasonable people than is necessary for a political consensus. (shrink)

The zombie, mocking all nomological arguments, gives rise to axiological considerations that also result in a vindication of the nomological paradigm. So the ‘philosophical benefit of zombies’ ultimately proves to be that they lead to an understanding they were originally invented to refute.

Our starting point is the question ‘What is mass’, what in particular enables mass to constitute duration: so that mass can be regarded as moving as well as at rest (the kinematic principle of relativity). In a thought experiment, this question is attacked here not from the perspective of mass itself, but from that of a standing light wave. In this model, mass-analogous structures can be re- constructed that can be in relative motion to each other. The (empirically known) constancy (...) of the speed of light in every reference system is not as- sumed here. However, it can be shown that the speed of light is identical in all systems constituted by mass-analogous structures that move uniformly relative to each other and that the speed of light moreover is the limiting speed of mo- tions. This indepence of the motion of light from the system of reference, this character of absoluteness, and the relativity of mass motions thus prove to be contrary but inextricably linked moments of the kinematic principle of relativi- ty: an interesting perspective concerning a philosophy of relativity theory. - The mathematical relationships are explained in more detail in the appendix. (shrink)

Ausgangspunkt ist die Frage, was Masse ist, wodurch sie insbesondere befähigt ist, Dauer zu konstituieren und deshalb - im Sinn des kinematischen Relativitätdprinzips - ebenso als bewegt wie als ruhend betrachtet werden kann. In einem Gedankenexperiment wird diese Frage, in Umkehrung der Perspektive, hier nicht von der Masse selbst, sondern von einer stehenden Lichtwelle her angegangen. In diesem Modell lassen sich masse-analoge Strukturen rekonstruieren, die in relativer Bewegung sein können. Die (empirisch bekannte) Unabhängigkeit der Lichtgeschwindigkeit vom Bezugssystem ist dabei nicht (...) vorausgesetzt. Doch kann gezeigt werden, dass die Lichtgeschwindigkeit Grenzgeschwindigkeit solcher relativer Bewegungen ist, dass dies für alle durch masse-analoge Strukturen konstituierte, relativ zueinander gleichförmig bewegten Bezugssysteme gilt und dass die Lichtgeschwindigkeit selbst in allen diesen Systemen gleich ist. Die Absolutheit der Lichtgeschwindigkeit und die Relativität der Massebewegungen erweisen sich so als zwar differente, aber intrinsisch zusammengehörende Momente des kinematischen Relativitätsprinzips: ein Beitrag zu einer Philosophie der Relativitätstheorie. - Die mathematischen Zusammenhänge werden im Anhang ausführlicher dargelegt. (shrink)

Mitochondrial replacement therapy requires oocytes of women whose mitochondrial DNA will be transmitted to resultant children. These techniques are scientifically, ethically and socially controversial; it is likely that some women who donate their oocytes for general in vitro fertilisation usage would nevertheless oppose their genetic material being used in MRT. The possibility of oocytes being used in MRT is therefore relevant to oocyte donation and should be included in the consent process when applicable. In present circumstances, specific consent should be (...) obtained. However, once MRT becomes more routine, such consent could be incorporated into the general consent process for oocyte donation. The reported lack of proper consent for MRT from the oocyte donor in the first baby born via the technique is an ethical failing and should be corrected in any future practice of MRT. (shrink)

Ethics committees like Institutional Review Boards and Research Ethics Committees are typically empowered to approve or reject proposed studies, typically conditional on certain conditions or revisions being met. While some have argued this power should be primarily a function of applying clear, codified requirements, most institutions and legal regimes allow discretion for IRBs to ethically evaluate studies, such as to ensure a favourable risk-benefit ratio, fair subject selection, adequate informed consent, and so forth. As a result, ethics committees typically make (...) moral demands on researchers: require them to act in a way the committee considers ethically right or appropriate. This paper argues that moral demands are legitimate only if publicly justifiable; and as a result, committee decisions are subject to a public justification requirement. Ethics committees can permissibly request for more information, changes to the research protocol or that the research is delayed or even stopped only if these demands are publicly justifiable. This latter claim is in turn justified on the basis that moral demands to φ are permissible only if we are in a position to know that the addressee ought to φ and that we are in a position to know a proposition only if it is publicly justifiable. This argument suggests that ethics committees must consciously and explicitly appeal to public reasons in their decision-making. In cases where public reasons cannot be offered, committees would not be permitted to reject a given study or make approval conditional on an amendment. (shrink)

Volume 19, Issue 7, July 2019, Page 28-30.

What role should legislation or policy play in avoiding the complications of in-vitro fertilization? In this article, we focus on single versus double embryo transfer, and assess three arguments in favour of mandatory single embryo transfer: risks to the mother, risks to resultant children, and costs to society. We highlight significant ethical concerns about each of these. Reproductive autonomy and non-paternalism are strong enough to outweigh the health concerns for the woman. Complications due to non-identity cast doubt on the extent (...) to which children are harmed. Twinning may offer an overall benefit rather than burden to society. Finally, including the future health costs for children in reproductive policy is inconsistent with other decisions. We conclude that mandatory single embryo transfer is not justified and that a number of countries should reconsider their current embryo transfer policy. (shrink)

The present investigation brings into view the philosophy of nature of German Idealism, a philosophical movement which emerged around the beginning of the nineteenth century. German Idealism appro- priated certain motivations of the Kantian philosophy and developed them further in a "speculative" manner (Engelhardt 1972, 1976, 2002). This powerful philosophical movement, associated above all with the names of Fichte, Schelling and Hegel - and moreover having nothing whatsoever to do with the "subjective idealism" of George Berkeley - was replaced by (...) philosophical positions designated roughly as metaphysics of the will, Marxism, life-philosophy, phenomenology and existentialism, as well as positivism, empiricism, philosophy of science, the linguistic turn, and analytic philosophy. These philosophical positions more or less still shape us today. German Idealism amounts to a virtual intellectual-historical antithesis to these movements and thus presents itself in retrospect as a striking alternative. The basis of Idealism - in its various respective forms - is the ideal <Ideelle>, and thus the opposite of that which is real. It continually takes as its task explaining the real in terms of the ideal, and this is especially true of the Idealists' philosophy of nature.' Is this a hopeless undertaking? Does Idealism not lack an empirical basis? Can one secure any solid ground whatsoever in the ether of the ideal? In what follows, I explain how, more than anyone else, Schelling and Hegel sought to handle this problem and to cope with it. By way of anticipation, a clear preference for the Hegelian philosophy of nature will emerge in what follows, a preference which may come as some surprise considering how much controversy has surrounded the significance of that view. The project of renewing a thoroughgoing philosophy of nature can meaningfully begin here. (shrink)

There are arguments for determinism. Admittedly, this is opposed by the fact of everyday experience of autonomy. In the following, it is argued for the compatibility of determinism and autonomy. Taking up considerations of Donald MacKay, a fatalistic attitude can be refuted as false. Repeatedly, attempts have been made to defend the possibility of autonomy with reference to quantum physical indeterminacy. But its statistical randomness clearly misses the meaning of autonomy. What is decisive, on the other hand, is the possibility (...) of knowledge, which opens up opportunities for planning, freedom of choice and ultimately 'self-choice'. Results of neurobiological research, especially Benjamin Libet's and more recently John-Dylan Haynes', seem to refute this: Actions are unconsciously initiated before conscious decision. But, as Libet has also shown, consciousness always has the possibility of a veto – and thus also of knowledge-driven action control. Ultimately, the idea of possible self-choice can thus become the determining condition. Only such a form of rational self-determination establishes a spiritual identity and at the same time represents the maximum of autonomy possible for human beings. (shrink)

Krause’s philosophy deserves to be memorized as the first link in a chain of thinking on animal rights that is still on the way today. Though Krause was not the first to talk of animal rights in the history of animal ethics, his theory of animal rights is pathbreaking in embedding a conception of animal rights in an all-encompassing metaphysical system. The essay situates Krause’s theory of animal rights in the framework of his general theory of rights and points to (...) the challenges Krause’s theory faces by the inevitability of trade-offs between animal and human rights. (shrink)

Seele kommt zweifellos schon ‚höheren‘ Tieren zu, die als solche über phänomenale Wahrnehmung verfügen. Als aufschlussreich erweist sich der kontrastierende Vergleich von Tier und Roboter: Was hat das Tier, was der Roboter nicht hat? Schlüsselfunktion kommt hier Hegels Deutung zu, die als eine Phänomenologie der ‚animalischen Seele‘ angesprochen werden kann. Sein Diktum ‚Nur ein Lebendiges fühlt Mangel‘ verweist auf das alles Organische durchwaltende Prinzip Selbsterhaltung als Grund des Seelischen: Alles, was das Tier wahrnimmt, hat dadurch existentiellen Sinn, Selbsterhaltungs-Sinn. Zugleich wird (...) deutlich, dass die Roboter-Wahrneh- mung nicht zur Sinn-Konstitution befähigt, sondern durch Sinn-Demenz charakterisiert ist. Konkret-systemtheoretisch wird die Sinnbezogenheit des Tiersubjekts hier als Emergenzphänomen desjenigen Systems gedeutet, das durch die Kooperative von Wahrnehmung, Bewertung und Verhalten (Perc-Eval-Act-System) konstituiert wird. In dieser emergentistischen Perspektive gibt es so gleichsam den Dualismus des ‚bloß Physischen‘ und des Ideell-Seelischen, der im Hinblick auf die insgesamt physische Basis zugleich ein Monismus ist. (shrink)

Previous efforts to bring the Hegelian dialectic closer to a clarification give reason for skepticism. The question: "What is dialectic", according to Dieter Henrich, "has remained without an answer so far". Hegel's objective-idealistic program is, however, so much linked to the possibility of a dialectical logic that it is an urgent desideratum to gain clarity about the stringency of dialectical argumentation. But this is only possible on the basis of a theory of dialectic. Hegel's own reflection on methods cannot (...) be considered sufficient in this respect. It does not enable us to defend the dialectical procedure against objections or to answer questions of method. In the following, a detailed reconstruction of the dialectic of 'being' and 'nothing' in Hegel's 'Science of Logic' will reveal basic structures of dialectical argumentation. As will be shown, antinomic structures play a key role. Such a 'reconstruction', however, will not be a simple confirmation of Hegelian texts, but will always have the character of a critique. In fact, it will turn out that in comparison with Hegel's development of categories, radical revisions are to be expected. ----- Bisherige Bemühungen, das Verfahren Hegelscher Dialektik einer Klärung näherzubringen, geben Anlass zur Skepsis. Die Frage: „Was ist Dialektik?“, so Dieter Henrich, sei „bisher ohne Antwort geblieben“. Das objektiv-idealistische Programm Hegels ist indes so sehr mit der Möglichkeit einer dialektischen Logik verknüpft, daß über die Stringenz dialektischer Argumentation Klarheit zu gewinnen ein dringliches Desiderat darstellt. Das aber ist nur auf der Grundlage einer Theorie der Dialektik möglich. Hegels eigene Methodenreflexion kann diesbezüglich nicht als zureichend erachtet werden. Sie versetzt uns nicht in die Lage, das dialektische Verfahren gegen Einwände zu verteidigen oder Methodenfragen zu beantworten. Im Folgenden sollen in einer detaillierten Rekonstruktion der Dialektik von ‘Sein’ und ‘Nichts’ in Hegels ‘Wissenschaft der Logik’ Grundstrukturen dialektischer Argumentation sichtbar gemacht werden. Wie gezeigt wird, kommt dabei antinomischen Strukturen eine Schlüsselfunktion zu. Eine solche 'Rekonstruktion' wird allerdings nicht eine umstandslose Bestätigung der Hegelschen Textvorlage sein können, sondern immer auch den Charakter einer Kritik haben. In der Tat wird sich ergeben, daß im Vergleich mit Hegels Kategorienentwicklung einschneidende Revisionen zu gewärtigen sind. (shrink)

Without doubt already ‘higher’ animals which as such have phenomenal perception possess an animalic soul. The contrasting comparison of animal and robot proves to be revealing: What does the animal have that the robot does not? A key role here plays Hegel’s interpretation, which can be addressed as a phenomenology of the ‘animalic soul’. His dictum ‘Only what is living feels a lack’ refers to the principle of self-preservation which governs everything organic. Concerning higher animals this too appears as the (...) basis of the soul: Everything, which the animal perceives thus has existential sense, self-preservation-sense. At the same time it becomes clear that robot perception is not capable of a constitution of sense, but is characterized by dementia of sense. Concretely systemtheoretically regarded, the relatedness to sense of the animal subject is here interpreted as an emergence phenomenon of the system constituted by the cooperative of perception, valuation and behavior (perc-val-act-system). In this emergentist perspective, there is, as it were, the dualism of solely-physical being and of immaterial-mental being, which at the same time is a monism with regard to the physical basis alltogether. (shrink)

Ziel der Untersuchung ist zu zeigen, inwiefern Hegels Charakterisierung des Schönen als ‚das sinnliche Scheinen der Idee‘ auch für die Deutung des Naturschönen Erklärungswert hat. Vorausgesetzt ist die für den Idea- lismus Hegelscher Prägung zentrale Doktrin, derzufolge der Natur Ideel- les zugrunde liegt. Schön sind dann Naturphänomene, in denen jener ideelle Grund der Natur durchscheint. Das Erfassen von Ideellem scheint ein Privileg geistiger Wesen zu sein. Dem stehen evolutionsbiologische Argumente entgegen, die dem Schönen einen positiven Selektionswert, etwa bei der sexuellen (...) Partnerwahl, zusprechen. Auch der Mensch hat stammesgeschichtliche Wurzeln, die in ihm weiter wirken. Doch sobald der Geist auf der evolutionären Bühne erscheint, herrscht das Biologische nicht länger mit der uneingeschränkten Macht, die es im Rahmen natürli- cher Selektion hat. Hegels Deutung des Schönen, auch des Naturschönen, ist wesentlich bezogen auf den Geist. Ich verdeutliche dies an einigen Exempeln (Schneekristall, musikalische Harmonie, Abendhimmel, Ge- birgslandschaft, organische Blüten- und Körperformen). Aber wodurch sind Naturschönheit und Kunstschönheit dann voneinander unterschie- den? Die Hervorbringungen der Natur sind lediglich Zufallskonstellatio- nen. Allerdings, so Hegel, hat der Zufall es ‘recht’ gemacht, d.h. hat er etwas reizend Stimmiges gefügt, gewahrt der Geist darin das im Sinnli- chen durchscheinende Ideelle. Eben darin wird, mit Adorno gesprochen, die gemeinsame Wurzel des Kunstschönen und des Naturschönen erkennbar. Wer das Naturschöne preist, begebe sich „an den Rand der Afterpoe- sie“, des Kitsches, meint Adorno. Gleichwohl sei es wahr zu sagen, „die Landschaft der Toscana sei schöner als die Umgebung von Gelsenkirchen“ (Adorno 1993, 110, 112). In der Tat. Doch was meinen wir, wenn wir Landschaften, Blumen, Sonnenuntergänge ‘schön’ nennen, und welche Kriterien bringen wir dafür in Anschlag? Im Folgenden möchte ich darle- gen, inwiefern Hegels Charakterisierung des Schönen als „das sinnliche Scheinen der Idee“ diesbezüglich erhellend und klärend ist. Hinweise auf Adornos ästhetische Theorie ergänzen diese Überlegungen. Dem stehen evolutionsbiologische Argumente entgegen, die zunehmend Einfluss auf die ästhetische Diskussion gewinnen. (shrink)

In this article, we propose the Fair Priority Model for COVID-19 vaccine distribution, and emphasize three fundamental values we believe should be considered when distributing a COVID-19 vaccine among countries: Benefiting people and limiting harm, prioritizing the disadvantaged, and equal moral concern for all individuals. The Priority Model addresses these values by focusing on mitigating three types of harms caused by COVID-19: death and permanent organ damage, indirect health consequences, such as health care system strain and stress, as well as (...) economic destruction. It proposes proceeding in three phases: the first addresses premature death, the second long-term health issues and economic harms, and the third aims to contain viral transmission fully and restore pre-pandemic activity. -/- To those who may deem an ethical framework irrelevant because of the belief that many countries will pursue "vaccine nationalism," we argue such a framework still has broad relevance. Reasonable national partiality would permit countries to focus on vaccine distribution within their borders up until the rate of transmission is below 1, at which point there would not be sufficient vaccine-preventable harm to justify retaining a vaccine. When a government reaches the limit of national partiality, it should release vaccines for other countries. -/- We also argue against two other recent proposals. Distributing a vaccine proportional to a country's population mistakenly assumes that equality requires treating differently situated countries identically. Prioritizing countries according to the number of front-line health care workers, the proportion of the population over 65, and the number of people with comorbidities within each country may exacerbate disadvantage and end up giving the vaccine in large part to wealthy nations. (shrink)

Hegel's Science of Logic makes the just not low claim to be an absolute, ultimate-grounded knowledge. This project, which could not be more ambitious, has no good press in our post-metaphysical age. However: That absolute knowledge absolutely cannot exist, cannot be claimed without self-contradiction. On the other hand, there can be no doubt about the fundamental finiteness of knowledge. But can absolute knowledge be finite knowledge? This leads to the problem of a self-explication of logic (in the sense of Hegel) (...) and further, as will be shown, to a new definition of the dialectical procedure. The stringency of which results from the fact that always exactly that implicit content is explicated that was generated by the preceding explication step itself and is thus concretely comprehensible. At the same time, a new implicit content is generated by this act of explication, which requires a new explication step, and so forth. In the dialectical procedure reinterpreted in this way, dialectical arguments are not beheld, guessed at or even surreptitiously obtained, but are methodically accountable. Thereby dialectics is understood as a self-explication of logic by logical means and thus as a proof of the possibility of ultimate-grounding in the form of absolute and nevertheless finite – and thus also fallible – knowledge. (shrink)